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Entry version 118 (17 Jun 2020)
Sequence version 2 (17 Apr 2007)
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Protein

Protein pitchfork

Gene

PIFO

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

During primary cilia disassembly, involved in cilia disassembly. Required specifically to control cilia retraction as well as the liberation and duplication of the basal body/centrosome. May act by stimulating AURKA activity at the basal body in a cell cycle-dependent manner.1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processCilium biogenesis/degradation

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Protein pitchfork
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:PIFO
Synonyms:C1orf88
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 1

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000173947.13

Human Gene Nomenclature Database

More...
HGNCi
HGNC:27009 PIFO

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
614234 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q8TCI5

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Cytoplasmic vesicle, Golgi apparatus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
128344

Open Targets

More...
OpenTargetsi
ENSG00000173947

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA142672472

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q8TCI5 Tbio

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
PIFO

Domain mapping of disease mutations (DMDM)

More...
DMDMi
145558868

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002845261 – 191Protein pitchforkAdd BLAST191

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q8TCI5

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q8TCI5

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q8TCI5

PeptideAtlas

More...
PeptideAtlasi
Q8TCI5

PRoteomics IDEntifications database

More...
PRIDEi
Q8TCI5

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
74140 [Q8TCI5-1]
74141 [Q8TCI5-2]
74142 [Q8TCI5-3]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q8TCI5

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q8TCI5

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000173947 Expressed in bronchial epithelial cell and 127 other tissues

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q8TCI5 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
ENSG00000173947 Tissue enhanced (brain, fallopian tube)

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with proteins involved in ciliary transport, including ARL13B, CETN1, KIF3A, RAB6A, RAB8A, TUBB1 and TUBG1.

Interacts with AURKA.

1 Publication

GO - Molecular functioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
126109, 11 interactors

Protein interaction database and analysis system

More...
IntActi
Q8TCI5, 7 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000358753

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q8TCI5 protein

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410IZVF Eukaryota
ENOG4111RA1 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000001017

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_098763_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q8TCI5

Identification of Orthologs from Complete Genome Data

More...
OMAi
QKEMTPH

Database of Orthologous Groups

More...
OrthoDBi
1094638at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q8TCI5

TreeFam database of animal gene trees

More...
TreeFami
TF328853

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR033602 Pitchfork

The PANTHER Classification System

More...
PANTHERi
PTHR31508 PTHR31508, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (3)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 3 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform. This section is only present in reviewed entries, i.e. in UniProtKB/Swiss-Prot.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket
Isoform 1 (identifier: Q8TCI5-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MCFSRADAAD NYPFGTCQQR KLFPHFHPPN LIGNKFVPLR GSPHRGPGCY
60 70 80 90 100
FSDGYGLAYD LSKIPTSIKG YTLGARTAVR FKPIQKEMTP HAGRYQKVSP
110 120 130 140 150
QQEKHKQNFA PFNVLVPRFK NYPKDTYYPS PGAYNPEKKP PPKIAWPMKF
160 170 180 190
GSPDWAQVPC LQKRTLKAEL STDKDFRKHR NRVAYLSLYY N
Length:191
Mass (Da):21,973
Last modified:April 17, 2007 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iCEEDE39D1F7381C5
GO
Isoform 2 (identifier: Q8TCI5-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     130-191: SPGAYNPEKK...RVAYLSLYYN → RYVSSLLVHFNKKSNRRKRST

Show »
Length:150
Mass (Da):17,315
Checksum:iCF54AB66EAE5B0F3
GO
Isoform 3 (identifier: Q8TCI5-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     54-86: Missing.

Show »
Length:158
Mass (Da):18,377
Checksum:iE6EA45A81BCFA44D
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti63K → R in BAB85081 (PubMed:14702039).Curated1
Sequence conflicti121N → D in AAH50319 (PubMed:15489334).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_06648480R → K Found in patients with severe ciliopathies and left-right asymmetry defects; inhibits AURKA activity. 1 PublicationCorresponds to variant dbSNP:rs150508940Ensembl.1
Natural variantiVAR_03176797K → N. Corresponds to variant dbSNP:rs15396Ensembl.1
Natural variantiVAR_031768105H → N2 PublicationsCorresponds to variant dbSNP:rs2184884Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_04204054 – 86Missing in isoform 3. 1 PublicationAdd BLAST33
Alternative sequenceiVSP_024557130 – 191SPGAY…SLYYN → RYVSSLLVHFNKKSNRRKRS T in isoform 2. 1 PublicationAdd BLAST62

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
HM237139 mRNA Translation: ADI86276.1
HM237140 mRNA Translation: ADI86277.1
AK074433 mRNA Translation: BAB85081.1
AK303897 mRNA Translation: BAG64829.1
AL356387 Genomic DNA No translation available.
BC029237 mRNA Translation: AAH29237.1
BC050319 mRNA Translation: AAH50319.1
BC093891 mRNA Translation: AAH93891.1
BC101501 mRNA Translation: AAI01502.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS72836.1 [Q8TCI5-3]
CCDS833.1 [Q8TCI5-1]

NCBI Reference Sequences

More...
RefSeqi
NP_001287760.1, NM_001300831.1 [Q8TCI5-3]
NP_857594.2, NM_181643.5 [Q8TCI5-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000369737; ENSP00000358752; ENSG00000173947 [Q8TCI5-3]
ENST00000369738; ENSP00000358753; ENSG00000173947 [Q8TCI5-1]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
128344

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:128344

UCSC genome browser

More...
UCSCi
uc001eaw.3 human [Q8TCI5-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
HM237139 mRNA Translation: ADI86276.1
HM237140 mRNA Translation: ADI86277.1
AK074433 mRNA Translation: BAB85081.1
AK303897 mRNA Translation: BAG64829.1
AL356387 Genomic DNA No translation available.
BC029237 mRNA Translation: AAH29237.1
BC050319 mRNA Translation: AAH50319.1
BC093891 mRNA Translation: AAH93891.1
BC101501 mRNA Translation: AAI01502.1
CCDSiCCDS72836.1 [Q8TCI5-3]
CCDS833.1 [Q8TCI5-1]
RefSeqiNP_001287760.1, NM_001300831.1 [Q8TCI5-3]
NP_857594.2, NM_181643.5 [Q8TCI5-1]

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

BioGRIDi126109, 11 interactors
IntActiQ8TCI5, 7 interactors
STRINGi9606.ENSP00000358753

PTM databases

iPTMnetiQ8TCI5
PhosphoSitePlusiQ8TCI5

Polymorphism and mutation databases

BioMutaiPIFO
DMDMi145558868

Proteomic databases

jPOSTiQ8TCI5
MassIVEiQ8TCI5
PaxDbiQ8TCI5
PeptideAtlasiQ8TCI5
PRIDEiQ8TCI5
ProteomicsDBi74140 [Q8TCI5-1]
74141 [Q8TCI5-2]
74142 [Q8TCI5-3]

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
53752 4 antibodies

The DNASU plasmid repository

More...
DNASUi
128344

Genome annotation databases

EnsembliENST00000369737; ENSP00000358752; ENSG00000173947 [Q8TCI5-3]
ENST00000369738; ENSP00000358753; ENSG00000173947 [Q8TCI5-1]
GeneIDi128344
KEGGihsa:128344
UCSCiuc001eaw.3 human [Q8TCI5-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
128344
DisGeNETi128344
EuPathDBiHostDB:ENSG00000173947.13

GeneCards: human genes, protein and diseases

More...
GeneCardsi
PIFO
HGNCiHGNC:27009 PIFO
HPAiENSG00000173947 Tissue enhanced (brain, fallopian tube)
MIMi614234 gene
neXtProtiNX_Q8TCI5
OpenTargetsiENSG00000173947
PharmGKBiPA142672472

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiENOG410IZVF Eukaryota
ENOG4111RA1 LUCA
GeneTreeiENSGT00390000001017
HOGENOMiCLU_098763_0_0_1
InParanoidiQ8TCI5
OMAiQKEMTPH
OrthoDBi1094638at2759
PhylomeDBiQ8TCI5
TreeFamiTF328853

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
128344 34 hits in 789 CRISPR screens

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
128344
PharosiQ8TCI5 Tbio

Protein Ontology

More...
PROi
PR:Q8TCI5
RNActiQ8TCI5 protein

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSG00000173947 Expressed in bronchial epithelial cell and 127 other tissues
GenevisibleiQ8TCI5 HS

Family and domain databases

InterProiView protein in InterPro
IPR033602 Pitchfork
PANTHERiPTHR31508 PTHR31508, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiPIFO_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q8TCI5
Secondary accession number(s): D9J0A2
, D9J0A3, Q4G0K4, Q52LJ6, Q5T5D5, Q5T5D6, Q8N310
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 17, 2007
Last sequence update: April 17, 2007
Last modified: June 17, 2020
This is version 118 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human chromosome 1
    Human chromosome 1: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
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