Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 149 (07 Oct 2020)
Sequence version 1 (01 Jun 2002)
Previous versions | rss
Add a publicationFeedback
Protein

Leucine-rich repeat-containing protein 20

Gene

LRRC20

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...
PathwayCommonsi
Q8TCA0

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Leucine-rich repeat-containing protein 20
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:LRRC20
ORF Names:UNQ2429/PRO4989
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 10

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000172731.13

Human Gene Nomenclature Database

More...
HGNCi
HGNC:23421, LRRC20

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q8TCA0

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
55222

Open Targets

More...
OpenTargetsi
ENSG00000172731

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA134935389

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q8TCA0, Tdark

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
LRRC20

Domain mapping of disease mutations (DMDM)

More...
DMDMi
74762612

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000844751 – 184Leucine-rich repeat-containing protein 20Add BLAST184

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei175PhosphoserineCombined sources1

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - PTMi

Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q8TCA0

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q8TCA0

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q8TCA0

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q8TCA0

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q8TCA0

PeptideAtlas

More...
PeptideAtlasi
Q8TCA0

PRoteomics IDEntifications database

More...
PRIDEi
Q8TCA0

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
74105 [Q8TCA0-1]
74106 [Q8TCA0-2]
74107 [Q8TCA0-3]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q8TCA0

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q8TCA0

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000172731, Expressed in quadriceps femoris and 214 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q8TCA0, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q8TCA0, HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
ENSG00000172731, Tissue enriched (skeletal)

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Hide details

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
120517, 8 interactors

Protein interaction database and analysis system

More...
IntActi
Q8TCA0, 4 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000348043

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q8TCA0, protein

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati51 – 72LRR 1Add BLAST22
Repeati75 – 96LRR 2Add BLAST22
Repeati98 – 120LRR 3Add BLAST23
Repeati121 – 141LRR 4Add BLAST21
Repeati145 – 167LRR 5Add BLAST23

Keywords - Domaini

Leucine-rich repeat, Repeat

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG4579, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00730000111199

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_070683_2_1_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q8TCA0

Identification of Orthologs from Complete Genome Data

More...
OMAi
QDNCNLD

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q8TCA0

TreeFam database of animal gene trees

More...
TreeFami
TF319816

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.80.10.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR001611, Leu-rich_rpt
IPR003591, Leu-rich_rpt_typical-subtyp
IPR032675, LRR_dom_sf
IPR037384, LRRC20

The PANTHER Classification System

More...
PANTHERi
PTHR16083:SF2, PTHR16083:SF2, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00560, LRR_1, 1 hit
PF13855, LRR_8, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00369, LRR_TYP, 3 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (3+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 3 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform. This section is only present in reviewed entries, i.e. in UniProtKB/Swiss-Prot.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 3 described isoforms and 2 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q8TCA0-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MLKKMGEAVA RVARKVNETV ESGSDTLDLA ECKLVSFPIG IYKVLRNVSG
60 70 80 90 100
QIHLITLANN ELKSLTSKFM TTFSQLRELH LEGNFLHRLP SEVSALQHLK
110 120 130 140 150
AIDLSRNQFQ DFPEQLTALP ALETINLEEN EIVDVPVEKL AAMPALRSIN
160 170 180
LRFNPLNAEV RVIAPPLIKF DMLMSPEGAR APLP
Length:184
Mass (Da):20,509
Last modified:June 1, 2002 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i1E0443D40FE672EC
GO
Isoform 2 (identifier: Q8TCA0-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     28-77: Missing.

Show »
Length:134
Mass (Da):14,887
Checksum:i16A5E552F6343379
GO
Isoform 3 (identifier: Q8TCA0-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     78-133: Missing.

Show »
Length:128
Mass (Da):14,105
Checksum:iDE63D1111E714C36
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A0A0MS58A0A0A0MS58_HUMAN
Leucine rich repeat containing 20, ...
LRRC20 hCG_1812779
115Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
X6RK58X6RK58_HUMAN
Leucine-rich repeat-containing prot...
LRRC20
174Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence BAA91849 differs from that shown. Reason: Erroneous termination. Extended C-terminus.Curated

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_01593328 – 77Missing in isoform 2. 1 PublicationAdd BLAST50
Alternative sequenceiVSP_01593478 – 133Missing in isoform 3. 1 PublicationAdd BLAST56

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AY358318 mRNA Translation: AAQ88684.1
AK001613 mRNA Translation: BAA91789.1
AK001706 mRNA Translation: BAA91849.1 Sequence problems.
AK094734 mRNA Translation: BAC04409.1
AC022532 Genomic DNA No translation available.
AL355138 Genomic DNA No translation available.
BC024001 mRNA Translation: AAH24001.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS7300.1 [Q8TCA0-3]
CCDS7301.1 [Q8TCA0-2]
CCDS7302.1 [Q8TCA0-1]

NCBI Reference Sequences

More...
RefSeqi
NP_001265140.1, NM_001278211.1 [Q8TCA0-1]
NP_001265141.1, NM_001278212.1 [Q8TCA0-1]
NP_001265142.1, NM_001278213.1 [Q8TCA0-2]
NP_001265143.1, NM_001278214.1
NP_060675.1, NM_018205.3 [Q8TCA0-3]
NP_060709.2, NM_018239.3 [Q8TCA0-2]
NP_997002.1, NM_207119.2 [Q8TCA0-1]
XP_016871863.1, XM_017016374.1 [Q8TCA0-1]
XP_016871864.1, XM_017016375.1 [Q8TCA0-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000355790; ENSP00000348043; ENSG00000172731 [Q8TCA0-1]
ENST00000357631; ENSP00000350255; ENSG00000172731 [Q8TCA0-3]
ENST00000358141; ENSP00000350860; ENSG00000172731 [Q8TCA0-2]
ENST00000373224; ENSP00000362321; ENSG00000172731 [Q8TCA0-1]
ENST00000395011; ENSP00000378458; ENSG00000172731 [Q8TCA0-2]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
55222

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:55222

UCSC genome browser

More...
UCSCi
uc001jqx.3, human [Q8TCA0-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY358318 mRNA Translation: AAQ88684.1
AK001613 mRNA Translation: BAA91789.1
AK001706 mRNA Translation: BAA91849.1 Sequence problems.
AK094734 mRNA Translation: BAC04409.1
AC022532 Genomic DNA No translation available.
AL355138 Genomic DNA No translation available.
BC024001 mRNA Translation: AAH24001.1
CCDSiCCDS7300.1 [Q8TCA0-3]
CCDS7301.1 [Q8TCA0-2]
CCDS7302.1 [Q8TCA0-1]
RefSeqiNP_001265140.1, NM_001278211.1 [Q8TCA0-1]
NP_001265141.1, NM_001278212.1 [Q8TCA0-1]
NP_001265142.1, NM_001278213.1 [Q8TCA0-2]
NP_001265143.1, NM_001278214.1
NP_060675.1, NM_018205.3 [Q8TCA0-3]
NP_060709.2, NM_018239.3 [Q8TCA0-2]
NP_997002.1, NM_207119.2 [Q8TCA0-1]
XP_016871863.1, XM_017016374.1 [Q8TCA0-1]
XP_016871864.1, XM_017016375.1 [Q8TCA0-1]

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

BioGRIDi120517, 8 interactors
IntActiQ8TCA0, 4 interactors
STRINGi9606.ENSP00000348043

PTM databases

iPTMnetiQ8TCA0
PhosphoSitePlusiQ8TCA0

Polymorphism and mutation databases

BioMutaiLRRC20
DMDMi74762612

Proteomic databases

EPDiQ8TCA0
jPOSTiQ8TCA0
MassIVEiQ8TCA0
MaxQBiQ8TCA0
PaxDbiQ8TCA0
PeptideAtlasiQ8TCA0
PRIDEiQ8TCA0
ProteomicsDBi74105 [Q8TCA0-1]
74106 [Q8TCA0-2]
74107 [Q8TCA0-3]

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
29015, 65 antibodies

The DNASU plasmid repository

More...
DNASUi
55222

Genome annotation databases

EnsembliENST00000355790; ENSP00000348043; ENSG00000172731 [Q8TCA0-1]
ENST00000357631; ENSP00000350255; ENSG00000172731 [Q8TCA0-3]
ENST00000358141; ENSP00000350860; ENSG00000172731 [Q8TCA0-2]
ENST00000373224; ENSP00000362321; ENSG00000172731 [Q8TCA0-1]
ENST00000395011; ENSP00000378458; ENSG00000172731 [Q8TCA0-2]
GeneIDi55222
KEGGihsa:55222
UCSCiuc001jqx.3, human [Q8TCA0-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
55222
DisGeNETi55222
EuPathDBiHostDB:ENSG00000172731.13

GeneCards: human genes, protein and diseases

More...
GeneCardsi
LRRC20
HGNCiHGNC:23421, LRRC20
HPAiENSG00000172731, Tissue enriched (skeletal)
neXtProtiNX_Q8TCA0
OpenTargetsiENSG00000172731
PharmGKBiPA134935389

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG4579, Eukaryota
GeneTreeiENSGT00730000111199
HOGENOMiCLU_070683_2_1_1
InParanoidiQ8TCA0
OMAiQDNCNLD
PhylomeDBiQ8TCA0
TreeFamiTF319816

Enzyme and pathway databases

PathwayCommonsiQ8TCA0

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
55222, 4 hits in 871 CRISPR screens

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
55222
PharosiQ8TCA0, Tdark

Protein Ontology

More...
PROi
PR:Q8TCA0
RNActiQ8TCA0, protein

Gene expression databases

BgeeiENSG00000172731, Expressed in quadriceps femoris and 214 other tissues
ExpressionAtlasiQ8TCA0, baseline and differential
GenevisibleiQ8TCA0, HS

Family and domain databases

Gene3Di3.80.10.10, 1 hit
InterProiView protein in InterPro
IPR001611, Leu-rich_rpt
IPR003591, Leu-rich_rpt_typical-subtyp
IPR032675, LRR_dom_sf
IPR037384, LRRC20
PANTHERiPTHR16083:SF2, PTHR16083:SF2, 1 hit
PfamiView protein in Pfam
PF00560, LRR_1, 1 hit
PF13855, LRR_8, 1 hit
SMARTiView protein in SMART
SM00369, LRR_TYP, 3 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiLRC20_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q8TCA0
Secondary accession number(s): Q5T6D4
, Q5T6D6, Q9NVA6, Q9NVG3
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 25, 2005
Last sequence update: June 1, 2002
Last modified: October 7, 2020
This is version 149 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human chromosome 10
    Human chromosome 10: entries, gene names and cross-references to MIM
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again