Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Meiosis 1 arrest protein

Gene

M1AP

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Required for meiosis I progression during spermatogenesis.By similarity

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

  • identical protein binding Source: IntAct

GO - Biological processi

  • cell differentiation Source: UniProtKB-KW
  • chromatin assembly Source: UniProtKB
  • female gamete generation Source: UniProtKB
  • male meiosis chromosome separation Source: UniProtKB
  • meiosis I Source: InterPro
  • RNA processing Source: UniProtKB
  • spermatogenesis Source: UniProtKB

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processDifferentiation, Spermatogenesis

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Meiosis 1 arrest protein
Alternative name(s):
Meiosis 1-arresting protein
Meiosis 1-associated protein
Spermatogenesis-associated protein 37
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:M1AP
Synonyms:C2orf65, SPATA37
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 2

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000159374.17

Human Gene Nomenclature Database

More...
HGNCi
HGNC:25183 M1AP

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q8TC57

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Cytoplasm

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

More...
OpenTargetsi
ENSG00000159374

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA162379401

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
M1AP

Domain mapping of disease mutations (DMDM)

More...
DMDMi
74730556

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003492681 – 530Meiosis 1 arrest proteinAdd BLAST530

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q8TC57

PeptideAtlas

More...
PeptideAtlasi
Q8TC57

PRoteomics IDEntifications database

More...
PRIDEi
Q8TC57

ProteomicsDB human proteome resource

More...
ProteomicsDBi
74090
74091 [Q8TC57-2]
74092 [Q8TC57-3]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q8TC57

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q8TC57

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000159374 Expressed in 84 organ(s), highest expression level in testis

CleanEx database of gene expression profiles

More...
CleanExi
HS_C2orf65

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q8TC57 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q8TC57 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA045420
HPA059302

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction_section%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="http://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated on a monthly basis. Each binary interaction is displayed on a separate line.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

GO - Molecular functioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
126265, 3 interactors

Protein interaction database and analysis system

More...
IntActi
Q8TC57, 16 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000290536

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

More...
ProteinModelPortali
Q8TC57

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q8TC57

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410IGUR Eukaryota
ENOG4111HE9 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000005656

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000261652

The HOVERGEN Database of Homologous Vertebrate Genes

More...
HOVERGENi
HBG106165

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q8TC57

Identification of Orthologs from Complete Genome Data

More...
OMAi
VQNQHEC

Database of Orthologous Groups

More...
OrthoDBi
EOG091G0QM1

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q8TC57

TreeFam database of animal gene trees

More...
TreeFami
TF329502

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR033587 M1AP

The PANTHER Classification System

More...
PANTHERi
PTHR28642 PTHR28642, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (4+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 4 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 4 described isoforms and 3 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q8TC57-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MHPGRTTGKG PSTHTQIDQQ PPRLLIVHIA LPSWADICTN LCEALQNFFS
60 70 80 90 100
LACSLMGPSR MSLFSLYMVQ DQHECILPFV QVKGNFARLQ TCISELRMLQ
110 120 130 140 150
REGCFRSQGA SLRLAVEDGL QQFKQYSRHV TTRAALTYTS LEITILTSQP
160 170 180 190 200
GKEVVKQLEE GLKDTDLARV RRFQVVEVTK GILEHVDSAS PVEDTSNDES
210 220 230 240 250
SILGTDIDLQ TIDNDIVSME IFFKAWLHNS GTDQEQIHLL LSSQCFSNIS
260 270 280 290 300
RPRDNPMCLK CDLQERLLCP SLLAGTADGS LRMDDPKGDF ITLYQMASQS
310 320 330 340 350
SASHYKLQVI KALKSSGLCE SLTYGLPFIL RPTSCWQLDW DELETNQQHF
360 370 380 390 400
HALCHSLLKR EWLLLAKGEP PGPGHSQRIP ASTFYVIMPS HSLTLLVKAV
410 420 430 440 450
ATRELMLPST FPLLPEDPHD DSLKNVESML DSLELEPTYN PLHVQSHLYS
460 470 480 490 500
HLSSIYAKPQ GRLHPHWESR APRKHPCKTG QLQTNRARAT VAPLPMTPVP
510 520 530
GRASKMPAAS KSSSDAFFLP SEWEKDPSRP
Length:530
Mass (Da):59,386
Last modified:June 1, 2002 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i14FF53B1F34E1884
GO
Isoform 2 (identifier: Q8TC57-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     359-365: KREWLLL → VSTHVPR
     366-530: Missing.

Note: No experimental confirmation available.
Show »
Length:365
Mass (Da):41,000
Checksum:iC9067DED1B67E011
GO
Isoform 3 (identifier: Q8TC57-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-282: Missing.
     359-427: Missing.

Note: No experimental confirmation available.
Show »
Length:179
Mass (Da):20,195
Checksum:i082F9AAA1CE12302
GO
Isoform 4 (identifier: Q8TC57-4) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     474-477: Missing.

Note: No experimental confirmation available.
Show »
Length:526
Mass (Da):58,920
Checksum:iB5CC281CAE4A7BB6
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
C9JPR9C9JPR9_HUMAN
Meiosis 1 arrest protein
M1AP
142Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F8WBR6F8WBR6_HUMAN
Meiosis 1 arrest protein
M1AP
155Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F8WEA5F8WEA5_HUMAN
Meiosis 1 arrest protein
M1AP
93Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti359K → E in BAH13233 (PubMed:14702039).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_0463355R → Q. Corresponds to variant dbSNP:rs3025980Ensembl.1
Natural variantiVAR_046336195T → P. Corresponds to variant dbSNP:rs7602159Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting. The information stored in this subsection is used to automatically construct alternative protein sequence(s) for display.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0352911 – 282Missing in isoform 3. 1 PublicationAdd BLAST282
Alternative sequenceiVSP_035292359 – 427Missing in isoform 3. 1 PublicationAdd BLAST69
Alternative sequenceiVSP_035293359 – 365KREWLLL → VSTHVPR in isoform 2. 1 Publication7
Alternative sequenceiVSP_035294366 – 530Missing in isoform 2. 1 PublicationAdd BLAST165
Alternative sequenceiVSP_055677474 – 477Missing in isoform 4. 1 Publication4

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AK130161 mRNA Translation: BAC85295.1
AK300188 mRNA Translation: BAH13233.1
AC005033 Genomic DNA Translation: AAX93225.1
AC007387 Genomic DNA No translation available.
CH471053 Genomic DNA Translation: EAW99611.1
BC014602 mRNA Translation: AAH14602.1
BC025997 mRNA Translation: AAH25997.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS33229.1 [Q8TC57-1]
CCDS62941.1 [Q8TC57-4]

NCBI Reference Sequences

More...
RefSeqi
NP_001268224.1, NM_001281295.1 [Q8TC57-2]
NP_001268225.1, NM_001281296.1 [Q8TC57-4]
NP_001308668.1, NM_001321739.1 [Q8TC57-1]
NP_620159.2, NM_138804.4 [Q8TC57-1]
XP_011530852.1, XM_011532550.2 [Q8TC57-1]
XP_011530853.1, XM_011532551.2 [Q8TC57-1]

UniGene gene-oriented nucleotide sequence clusters

More...
UniGenei
Hs.348645

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000290536; ENSP00000290536; ENSG00000159374 [Q8TC57-1]
ENST00000409585; ENSP00000386793; ENSG00000159374 [Q8TC57-4]
ENST00000536235; ENSP00000445662; ENSG00000159374 [Q8TC57-4]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
130951

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:130951

UCSC genome browser

More...
UCSCi
uc002smy.3 human [Q8TC57-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK130161 mRNA Translation: BAC85295.1
AK300188 mRNA Translation: BAH13233.1
AC005033 Genomic DNA Translation: AAX93225.1
AC007387 Genomic DNA No translation available.
CH471053 Genomic DNA Translation: EAW99611.1
BC014602 mRNA Translation: AAH14602.1
BC025997 mRNA Translation: AAH25997.1
CCDSiCCDS33229.1 [Q8TC57-1]
CCDS62941.1 [Q8TC57-4]
RefSeqiNP_001268224.1, NM_001281295.1 [Q8TC57-2]
NP_001268225.1, NM_001281296.1 [Q8TC57-4]
NP_001308668.1, NM_001321739.1 [Q8TC57-1]
NP_620159.2, NM_138804.4 [Q8TC57-1]
XP_011530852.1, XM_011532550.2 [Q8TC57-1]
XP_011530853.1, XM_011532551.2 [Q8TC57-1]
UniGeneiHs.348645

3D structure databases

ProteinModelPortaliQ8TC57
SMRiQ8TC57
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi126265, 3 interactors
IntActiQ8TC57, 16 interactors
STRINGi9606.ENSP00000290536

PTM databases

iPTMnetiQ8TC57
PhosphoSitePlusiQ8TC57

Polymorphism and mutation databases

BioMutaiM1AP
DMDMi74730556

Proteomic databases

PaxDbiQ8TC57
PeptideAtlasiQ8TC57
PRIDEiQ8TC57
ProteomicsDBi74090
74091 [Q8TC57-2]
74092 [Q8TC57-3]

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000290536; ENSP00000290536; ENSG00000159374 [Q8TC57-1]
ENST00000409585; ENSP00000386793; ENSG00000159374 [Q8TC57-4]
ENST00000536235; ENSP00000445662; ENSG00000159374 [Q8TC57-4]
GeneIDi130951
KEGGihsa:130951
UCSCiuc002smy.3 human [Q8TC57-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
130951
EuPathDBiHostDB:ENSG00000159374.17

GeneCards: human genes, protein and diseases

More...
GeneCardsi
M1AP
HGNCiHGNC:25183 M1AP
HPAiHPA045420
HPA059302
neXtProtiNX_Q8TC57
OpenTargetsiENSG00000159374
PharmGKBiPA162379401

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiENOG410IGUR Eukaryota
ENOG4111HE9 LUCA
GeneTreeiENSGT00390000005656
HOGENOMiHOG000261652
HOVERGENiHBG106165
InParanoidiQ8TC57
OMAiVQNQHEC
OrthoDBiEOG091G0QM1
PhylomeDBiQ8TC57
TreeFamiTF329502

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
M1AP human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
130951

Protein Ontology

More...
PROi
PR:Q8TC57

Gene expression databases

BgeeiENSG00000159374 Expressed in 84 organ(s), highest expression level in testis
CleanExiHS_C2orf65
ExpressionAtlasiQ8TC57 baseline and differential
GenevisibleiQ8TC57 HS

Family and domain databases

InterProiView protein in InterPro
IPR033587 M1AP
PANTHERiPTHR28642 PTHR28642, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiM1AP_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q8TC57
Secondary accession number(s): B7Z6E7
, E9PGG8, Q6ZP30, Q96L07
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 2, 2008
Last sequence update: June 1, 2002
Last modified: November 7, 2018
This is version 106 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 2
    Human chromosome 2: entries, gene names and cross-references to MIM
  2. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  3. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again