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Entry version 117 (29 Sep 2021)
Sequence version 1 (01 Jun 2002)
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Protein

Testis-expressed protein 47

Gene

TEX47

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...
PathwayCommonsi
Q8TBZ9

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Testis-expressed protein 47
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:TEX47Imported
Synonyms:C7orf62
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 7

Organism-specific databases

Human Gene Nomenclature Database

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HGNCi
HGNC:22402, TEX47

neXtProt; the human protein knowledge platform

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neXtProti
NX_Q8TBZ9

Eukaryotic Pathogen, Vector and Host Database Resources

More...
VEuPathDBi
HostDB:ENSG00000164645

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

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OpenTargetsi
ENSG00000164645

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA162380726

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q8TBZ9, Tdark

Genetic variation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
TEX47

Domain mapping of disease mutations (DMDM)

More...
DMDMi
74730535

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003218271 – 253Testis-expressed protein 47Add BLAST253

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

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jPOSTi
Q8TBZ9

MassIVE - Mass Spectrometry Interactive Virtual Environment

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MassIVEi
Q8TBZ9

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q8TBZ9

PeptideAtlas

More...
PeptideAtlasi
Q8TBZ9

PRoteomics IDEntifications database

More...
PRIDEi
Q8TBZ9

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
74063

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q8TBZ9

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q8TBZ9

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Testis-specific.Curated

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000164645, Expressed in testis and 31 other tissues

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q8TBZ9, HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
ENSG00000164645, Tissue enriched (testis)

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction_section">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

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BioGRIDi
128554, 1 interactor

Protein interaction database and analysis system

More...
IntActi
Q8TBZ9, 1 interactor

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000297203

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q8TBZ9, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q8TBZ9

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG502RYKR, Eukaryota

Ensembl GeneTree

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GeneTreei
ENSGT00390000005565

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_089495_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q8TBZ9

Identification of Orthologs from Complete Genome Data

More...
OMAi
KAPVMYL

Database of Orthologous Groups

More...
OrthoDBi
1274273at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q8TBZ9

TreeFam database of animal gene trees

More...
TreeFami
TF329731

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q8TBZ9-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSFSVHNQKG SKRPLPLEPL LFLQVPRSNY LHFQEEKQRL HLKKFLLDRM
60 70 80 90 100
FLVAKIQANV ERKDVADYYE QMFQSVLKHH LGEAVTGLLL IYPTSILHIL
110 120 130 140 150
ESSSDTLYKV LLDYIGHVKD ETVFFIQQMK IIVISHNIPM RLFMQWHVSV
160 170 180 190 200
IKVPVMYLDD VTQSQSLKEV ITDFLTQTHK LSLYLCQTMK VGTKGPGDNL
210 220 230 240 250
HQVAPDLLLP EQIIKYLCKS EEFMDPATFI NMYNRPIHIT LDSEVVWPAP

SRF
Length:253
Mass (Da):29,483
Last modified:June 1, 2002 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i6D92F6C65D6F7DD5
GO

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_03935148D → H. Corresponds to variant dbSNP:rs2373396Ensembl.1
Natural variantiVAR_039352126I → V. Corresponds to variant dbSNP:rs2293583Ensembl.1
Natural variantiVAR_039353186C → S. Corresponds to variant dbSNP:rs34276371Ensembl.1
Natural variantiVAR_039355221E → A. Corresponds to variant dbSNP:rs2373398Ensembl.1
Natural variantiVAR_039354221E → K. Corresponds to variant dbSNP:rs2373397Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AC002127 Genomic DNA No translation available.
CH236949 Genomic DNA Translation: EAL24169.1
CH471091 Genomic DNA Translation: EAW76902.1
BC028365 mRNA Translation: AAH28365.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS34678.1

NCBI Reference Sequences

More...
RefSeqi
NP_689919.1, NM_152706.3
XP_011514206.1, XM_011515904.2

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000297203; ENSP00000297203; ENSG00000164645

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
219557

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:219557

UCSC genome browser

More...
UCSCi
uc003ujv.4, human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC002127 Genomic DNA No translation available.
CH236949 Genomic DNA Translation: EAL24169.1
CH471091 Genomic DNA Translation: EAW76902.1
BC028365 mRNA Translation: AAH28365.1
CCDSiCCDS34678.1
RefSeqiNP_689919.1, NM_152706.3
XP_011514206.1, XM_011515904.2

3D structure databases

SMRiQ8TBZ9
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi128554, 1 interactor
IntActiQ8TBZ9, 1 interactor
STRINGi9606.ENSP00000297203

PTM databases

iPTMnetiQ8TBZ9
PhosphoSitePlusiQ8TBZ9

Genetic variation databases

BioMutaiTEX47
DMDMi74730535

Proteomic databases

jPOSTiQ8TBZ9
MassIVEiQ8TBZ9
PaxDbiQ8TBZ9
PeptideAtlasiQ8TBZ9
PRIDEiQ8TBZ9
ProteomicsDBi74063

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
15398, 60 antibodies

The DNASU plasmid repository

More...
DNASUi
219557

Genome annotation databases

EnsembliENST00000297203; ENSP00000297203; ENSG00000164645
GeneIDi219557
KEGGihsa:219557
UCSCiuc003ujv.4, human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
219557

GeneCards: human genes, protein and diseases

More...
GeneCardsi
TEX47
HGNCiHGNC:22402, TEX47
HPAiENSG00000164645, Tissue enriched (testis)
neXtProtiNX_Q8TBZ9
OpenTargetsiENSG00000164645
PharmGKBiPA162380726
VEuPathDBiHostDB:ENSG00000164645

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiENOG502RYKR, Eukaryota
GeneTreeiENSGT00390000005565
HOGENOMiCLU_089495_0_0_1
InParanoidiQ8TBZ9
OMAiKAPVMYL
OrthoDBi1274273at2759
PhylomeDBiQ8TBZ9
TreeFamiTF329731

Enzyme and pathway databases

PathwayCommonsiQ8TBZ9

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
219557, 8 hits in 990 CRISPR screens

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
219557
PharosiQ8TBZ9, Tdark

Protein Ontology

More...
PROi
PR:Q8TBZ9
RNActiQ8TBZ9, protein

Gene expression databases

BgeeiENSG00000164645, Expressed in testis and 31 other tissues
GenevisibleiQ8TBZ9, HS

Family and domain databases

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiTEX47_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q8TBZ9
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 26, 2008
Last sequence update: June 1, 2002
Last modified: September 29, 2021
This is version 117 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Technical termi

Reference proteome

Documents

  1. Human chromosome 7
    Human chromosome 7: entries, gene names and cross-references to MIM
  2. Human entries with genetic variants
    List of human entries with genetic variants
  3. Human variants curated from literature reports
    Index of human variants curated from literature reports
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