Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

UniProtKB - Q8TBZ5 (ZN502_HUMAN)

Entry version 154 (02 Dec 2020)
Sequence version 1 (01 Jun 2002)
Previous versions | rss
Add a publicationFeedback
Protein

Zinc finger protein 502

Gene

ZNF502

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May be involved in transcriptional regulation.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section specifies the position(s) and type(s) of zinc fingers within the protein.<p><a href='/help/zn_fing' target='_top'>More...</a></p>Zinc fingeri155 – 177C2H2-type 1PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri183 – 205C2H2-type 2PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri211 – 233C2H2-type 3PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri239 – 261C2H2-type 4PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri267 – 289C2H2-type 5PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri295 – 317C2H2-type 6PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri323 – 345C2H2-type 7PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri351 – 373C2H2-type 8PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri379 – 401C2H2-type 9PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri407 – 429C2H2-type 10PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri435 – 457C2H2-type 11PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri463 – 485C2H2-type 12PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri491 – 513C2H2-type 13PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri519 – 541C2H2-type 14PROSITE-ProRule annotationAdd BLAST23

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDNA-binding
Biological processHost-virus interaction, Transcription, Transcription regulation
LigandMetal-binding, Zinc

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...PathwayCommonsi		Q8TBZ5

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Zinc finger protein 502
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ZNF502
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componentsi: Chromosome 3, Unplaced

Organism-specific databases

Eukaryotic Pathogen and Host Database Resources

More...EuPathDBi		HostDB:ENSG00000196653.11

Human Gene Nomenclature Database

More...HGNCi		HGNC:23718, ZNF502

neXtProt; the human protein knowledge platform

More...neXtProti		NX_Q8TBZ5

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...DisGeNETi		91392

Open Targets

More...OpenTargetsi		ENSG00000196653

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...PharmGKBi		PA134866656

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...Pharosi		Q8TBZ5, Tbio

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...BioMutai		ZNF502

Domain mapping of disease mutations (DMDM)

More...DMDMi		45477319

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000476231 – 544Zinc finger protein 502Add BLAST544

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section describes <strong>covalent linkages</strong> of various types formed <strong>between two proteins (interchain cross-links)</strong> or <strong>between two parts of the same protein (intrachain cross-links)</strong>, except the disulfide bonds that are annotated in the <a href="http://www.uniprot.org/manual/disulfid">'Disulfide bond'</a> subsection.<p><a href='/help/crosslnk' target='_top'>More...</a></p>Cross-linki43Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources

Keywords - PTMi

Isopeptide bond, Ubl conjugation

Proteomic databases

Encyclopedia of Proteome Dynamics

More...EPDi		Q8TBZ5

jPOST - Japan Proteome Standard Repository/Database

More...jPOSTi		Q8TBZ5

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...MassIVEi		Q8TBZ5

MaxQB - The MaxQuant DataBase

More...MaxQBi		Q8TBZ5

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		Q8TBZ5

PeptideAtlas

More...PeptideAtlasi		Q8TBZ5

PRoteomics IDEntifications database

More...PRIDEi		Q8TBZ5

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		74060

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		Q8TBZ5

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		Q8TBZ5

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSG00000196653, Expressed in secondary oocyte and 200 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		Q8TBZ5, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		Q8TBZ5, HS

Organism-specific databases

Human Protein Atlas

More...HPAi		ENSG00000196653, Low tissue specificity

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

(Microbial infection) Interacts with human respiratory syncytial virus (HRSV) matrix protein; this interaction probably facilitates viral release.

1 Publication

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Hide details

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		124825, 3 interactors

Protein interaction database and analysis system

More...IntActi		Q8TBZ5, 2 interactors

STRING: functional protein association networks

More...STRINGi		9606.ENSP00000296091

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		Q8TBZ5, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		Q8TBZ5

Database of comparative protein structure models

More...ModBasei		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the krueppel C2H2-type zinc-finger protein family.Curated

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri155 – 177C2H2-type 1PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri183 – 205C2H2-type 2PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri211 – 233C2H2-type 3PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri239 – 261C2H2-type 4PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri267 – 289C2H2-type 5PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri295 – 317C2H2-type 6PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri323 – 345C2H2-type 7PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri351 – 373C2H2-type 8PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri379 – 401C2H2-type 9PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri407 – 429C2H2-type 10PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri435 – 457C2H2-type 11PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri463 – 485C2H2-type 12PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri491 – 513C2H2-type 13PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri519 – 541C2H2-type 14PROSITE-ProRule annotationAdd BLAST23

Keywords - Domaini

Repeat, Zinc-finger

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG1721, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00940000163095

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_002678_44_0_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q8TBZ5

Identification of Orthologs from Complete Genome Data

More...OMAi		WETSNIH

Database of Orthologous Groups

More...OrthoDBi		1318335at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		Q8TBZ5

TreeFam database of animal gene trees

More...TreeFami		TF341817

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR036236, Znf_C2H2_sf
IPR013087, Znf_C2H2_type

Pfam protein domain database

More...Pfami		View protein in Pfam
PF00096, zf-C2H2, 12 hits

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00355, ZnF_C2H2, 14 hits

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF57667, SSF57667, 8 hits

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS00028, ZINC_FINGER_C2H2_1, 14 hits
PS50157, ZINC_FINGER_C2H2_2, 14 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

Q8TBZ5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MLNMQGAEER DIRRETCPGW VNKNKPALEQ DVCKIDSSGI VVKRFQEDEY 
        60         70         80         90        100
QDSTFEEKYA CEGMKENSPR EIAESCLFQE GGFGRITFIH KEAPPEIISQ 
       110        120        130        140        150
GYNFEKSLLL TSSLVTRLRV STEESLHQWE TSNIQTNDIS DQSKCPTLCT 
       160        170        180        190        200
QKKSWKCNEC GKTFTQSSSL TQHQRTHTGE RPYTCEECGK AFSRSSFLVQ 
       210        220        230        240        250
HQRIHTGVKP YGCEQCGKTF RCRSFLTQHQ RIHTGEKPYK CNECGNSFRN 
       260        270        280        290        300
HSHLTEHQRI HTGEKPYKCN RCGKAFNQNT HLIHHQRIHT GEKPYICSEC 
       310        320        330        340        350
GSSFRKHSNL TQHQRIHTGE KPHKCDECGK TFQTKANLSQ HQRIHSGEKP 
       360        370        380        390        400
YKCKECGKAF CQSPSLIKHQ RIHTGEKPYK CKECGKAFTQ STPLTKHQRI 
       410        420        430        440        450
HTGERPYKCS ECGKAFIQSI CLIRHQRSHT GEKPYKCNEC GKGFNQNTCL 
       460        470        480        490        500
TQHMRIHTGE KPYKCKECGK AFAHSSSLTE HHRTHTGEKL YKCSECEKTF 
       510        520        530        540 
RKYAHLSEHY RIHTGEKPYE CIECGKFFRH SSVLFRHQKL HSGD
Length:544
Mass (Da):62,920
Last modified:June 1, 2002 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i63437B670A6B22D0
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
C9JLT3C9JLT3_HUMAN
Zinc finger protein 502
ZNF502
155Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_03357428L → P. Corresponds to variant dbSNP:rs6798400Ensembl.1
Natural variantiVAR_061953174Q → R. Corresponds to variant dbSNP:rs56084453Ensembl.1
Natural variantiVAR_024220243E → A. Corresponds to variant dbSNP:rs7640654Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
BC028377 mRNA Translation: AAH28377.1

The Consensus CDS (CCDS) project

More...CCDSi		CCDS2719.1

NCBI Reference Sequences

More...RefSeqi		NP_001127912.1, NM_001134440.1
NP_001127913.1, NM_001134441.1
NP_001127914.1, NM_001134442.1
NP_001269809.1, NM_001282880.1
NP_149987.2, NM_033210.4
XP_016862929.1, XM_017007440.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000296091; ENSP00000296091; ENSG00000196653
ENST00000436624; ENSP00000406469; ENSG00000196653
ENST00000449836; ENSP00000397390; ENSG00000196653
ENST00000626630; ENSP00000487139; ENSG00000281448
ENST00000628995; ENSP00000485847; ENSG00000281448
ENST00000630464; ENSP00000486576; ENSG00000281448

Database of genes from NCBI RefSeq genomes

More...GeneIDi		91392

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hsa:91392

UCSC genome browser

More...UCSCi		uc003cns.4, human

Keywords - Coding sequence diversityi

Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC028377 mRNA Translation: AAH28377.1
CCDSiCCDS2719.1
RefSeqiNP_001127912.1, NM_001134440.1
NP_001127913.1, NM_001134441.1
NP_001127914.1, NM_001134442.1
NP_001269809.1, NM_001282880.1
NP_149987.2, NM_033210.4
XP_016862929.1, XM_017007440.1

3D structure databases

SMRiQ8TBZ5
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi124825, 3 interactors
IntActiQ8TBZ5, 2 interactors
STRINGi9606.ENSP00000296091

PTM databases

iPTMnetiQ8TBZ5
PhosphoSitePlusiQ8TBZ5

Polymorphism and mutation databases

BioMutaiZNF502
DMDMi45477319

Proteomic databases

EPDiQ8TBZ5
jPOSTiQ8TBZ5
MassIVEiQ8TBZ5
MaxQBiQ8TBZ5
PaxDbiQ8TBZ5
PeptideAtlasiQ8TBZ5
PRIDEiQ8TBZ5
ProteomicsDBi74060

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...Antibodypediai		29472, 110 antibodies

The DNASU plasmid repository

More...DNASUi		91392

Genome annotation databases

EnsembliENST00000296091; ENSP00000296091; ENSG00000196653
ENST00000436624; ENSP00000406469; ENSG00000196653
ENST00000449836; ENSP00000397390; ENSG00000196653
ENST00000626630; ENSP00000487139; ENSG00000281448
ENST00000628995; ENSP00000485847; ENSG00000281448
ENST00000630464; ENSP00000486576; ENSG00000281448
GeneIDi91392
KEGGihsa:91392
UCSCiuc003cns.4, human

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		91392
DisGeNETi91392
EuPathDBiHostDB:ENSG00000196653.11

GeneCards: human genes, protein and diseases

More...GeneCardsi		ZNF502
HGNCiHGNC:23718, ZNF502
HPAiENSG00000196653, Low tissue specificity
neXtProtiNX_Q8TBZ5
OpenTargetsiENSG00000196653
PharmGKBiPA134866656

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

eggNOGiKOG1721, Eukaryota
GeneTreeiENSGT00940000163095
HOGENOMiCLU_002678_44_0_1
InParanoidiQ8TBZ5
OMAiWETSNIH
OrthoDBi1318335at2759
PhylomeDBiQ8TBZ5
TreeFamiTF341817

Enzyme and pathway databases

PathwayCommonsiQ8TBZ5

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		91392, 1 hit in 865 CRISPR screens

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		91392
PharosiQ8TBZ5, Tbio

Protein Ontology

More...PROi		PR:Q8TBZ5
RNActiQ8TBZ5, protein

Gene expression databases

BgeeiENSG00000196653, Expressed in secondary oocyte and 200 other tissues
ExpressionAtlasiQ8TBZ5, baseline and differential
GenevisibleiQ8TBZ5, HS

Family and domain databases

InterProiView protein in InterPro
IPR036236, Znf_C2H2_sf
IPR013087, Znf_C2H2_type
PfamiView protein in Pfam
PF00096, zf-C2H2, 12 hits
SMARTiView protein in SMART
SM00355, ZnF_C2H2, 14 hits
SUPFAMiSSF57667, SSF57667, 8 hits
PROSITEiView protein in PROSITE
PS00028, ZINC_FINGER_C2H2_1, 14 hits
PS50157, ZINC_FINGER_C2H2_2, 14 hits

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiZN502_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q8TBZ5
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 15, 2004
Last sequence update: June 1, 2002
Last modified: December 2, 2020
This is version 154 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human chromosome 3
    Human chromosome 3: entries, gene names and cross-references to MIM
  2. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  3. SIMILARITY comments
    Index of protein domains and families
  4. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again