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Entry version 142 (12 Aug 2020)
Sequence version 1 (01 Jun 2002)
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Protein

Solute carrier family 25 member 40

Gene

SLC25A40

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processTransport

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...
PathwayCommonsi
Q8TBP6

Protein family/group databases

Transport Classification Database

More...
TCDBi
2.A.29.14.6, the mitochondrial carrier (mc) family

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Solute carrier family 25 member 40
Alternative name(s):
Mitochondrial carrier family protein
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:SLC25A40
Synonyms:MCFP
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 7

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000075303.12

Human Gene Nomenclature Database

More...
HGNCi
HGNC:29680, SLC25A40

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
610821, gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q8TBP6

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei19 – 39Helical; Name=1Sequence analysisAdd BLAST21
Transmembranei103 – 123Helical; Name=2Sequence analysisAdd BLAST21
Transmembranei142 – 162Helical; Name=3Sequence analysisAdd BLAST21
Transmembranei199 – 220Helical; Name=4Sequence analysisAdd BLAST22
Transmembranei239 – 259Helical; Name=5Sequence analysisAdd BLAST21
Transmembranei298 – 318Helical; Name=6Sequence analysisAdd BLAST21

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion inner membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
55972

Open Targets

More...
OpenTargetsi
ENSG00000075303

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA162403655

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q8TBP6, Tdark

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
SLC25A40

Domain mapping of disease mutations (DMDM)

More...
DMDMi
74751387

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002918091 – 338Solute carrier family 25 member 40Add BLAST338

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q8TBP6

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q8TBP6

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q8TBP6

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q8TBP6

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q8TBP6

PeptideAtlas

More...
PeptideAtlasi
Q8TBP6

PRoteomics IDEntifications database

More...
PRIDEi
Q8TBP6

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
74037

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q8TBP6

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q8TBP6

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000075303, Expressed in adrenal tissue and 212 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q8TBP6, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q8TBP6, HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
ENSG00000075303, Low tissue specificity

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
121018, 2 interactors

Protein interaction database and analysis system

More...
IntActi
Q8TBP6, 2 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000344831

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q8TBP6, protein

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati13 – 131Solcar 1Add BLAST119
Repeati139 – 223Solcar 2Add BLAST85
Repeati233 – 327Solcar 3Add BLAST95

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Keywords - Domaini

Repeat, Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG0761, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000160249

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_015166_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q8TBP6

KEGG Orthology (KO)

More...
KOi
K15119

Identification of Orthologs from Complete Genome Data

More...
OMAi
WPIYEYL

Database of Orthologous Groups

More...
OrthoDBi
1007936at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q8TBP6

TreeFam database of animal gene trees

More...
TreeFami
TF314720

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.50.40.10, 2 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR002067, Mit_carrier
IPR018108, Mitochondrial_sb/sol_carrier
IPR023395, Mt_carrier_dom_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00153, Mito_carr, 3 hits

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR00926, MITOCARRIER

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF103506, SSF103506, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50920, SOLCAR, 3 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All

Q8TBP6-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MDPETRGQEI IKVTPLQQML ASCTGAILTS VIVTPLDVVK IRLQAQNNPL
60 70 80 90 100
PKGKCFVYSN GLMDHLCVCE EGGNKLWYKK PGNFQGTLDA FFKIIRNEGI
110 120 130 140 150
KSLWSGLPPT LVMAVPATVI YFTCYDQLSA LLRSKLGENE TCIPIVAGIV
160 170 180 190 200
ARFGAVTVIS PLELIRTKMQ SKKFSYVELH RFVSKKVSED GWISLWRGWA
210 220 230 240 250
PTVLRDVPFS AMYWYNYEIL KKWLCEKSGL YEPTFMINFT SGALSGSFAA
260 270 280 290 300
VATLPFDVVK TQKQTQLWTY ESHKISMPLH MSTWIIMKNI VAKNGFSGLF
310 320 330
SGLIPRLIKI APACAIMIST YEFGKAFFQK QNVRRQQY
Length:338
Mass (Da):38,125
Last modified:June 1, 2002 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i19F3AC921F5A6961
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
F8WEL8F8WEL8_HUMAN
Solute carrier family 25 member 40
SLC25A40
37Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F2Z3Q4F2Z3Q4_HUMAN
Solute carrier family 25 member 40
SLC25A40
36Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti71E → K in BAD96740 (Ref. 3) Curated1
Sequence conflicti161P → Q in AAF17225 (Ref. 1) Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_079372105S → N1 PublicationCorresponds to variant dbSNP:rs200954020Ensembl.1
Natural variantiVAR_032863123T → I. Corresponds to variant dbSNP:rs724665Ensembl.1
Natural variantiVAR_032864186K → Q. Corresponds to variant dbSNP:rs3213633Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AF125531 mRNA Translation: AAF17225.1
AK223020 mRNA Translation: BAD96740.1
AK290848 mRNA Translation: BAF83537.1
AC003083 Genomic DNA Translation: AAS07443.1
CH236949 Genomic DNA Translation: EAL24171.1
CH471091 Genomic DNA Translation: EAW76933.1
CH471091 Genomic DNA Translation: EAW76935.1
BC027322 mRNA Translation: AAH27322.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS5610.1

NCBI Reference Sequences

More...
RefSeqi
NP_061331.2, NM_018843.3

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000341119; ENSP00000344831; ENSG00000075303

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
55972

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:55972

UCSC genome browser

More...
UCSCi
uc003uje.4, human

Keywords - Coding sequence diversityi

Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF125531 mRNA Translation: AAF17225.1
AK223020 mRNA Translation: BAD96740.1
AK290848 mRNA Translation: BAF83537.1
AC003083 Genomic DNA Translation: AAS07443.1
CH236949 Genomic DNA Translation: EAL24171.1
CH471091 Genomic DNA Translation: EAW76933.1
CH471091 Genomic DNA Translation: EAW76935.1
BC027322 mRNA Translation: AAH27322.1
CCDSiCCDS5610.1
RefSeqiNP_061331.2, NM_018843.3

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

BioGRIDi121018, 2 interactors
IntActiQ8TBP6, 2 interactors
STRINGi9606.ENSP00000344831

Protein family/group databases

TCDBi2.A.29.14.6, the mitochondrial carrier (mc) family

PTM databases

iPTMnetiQ8TBP6
PhosphoSitePlusiQ8TBP6

Polymorphism and mutation databases

BioMutaiSLC25A40
DMDMi74751387

Proteomic databases

EPDiQ8TBP6
jPOSTiQ8TBP6
MassIVEiQ8TBP6
MaxQBiQ8TBP6
PaxDbiQ8TBP6
PeptideAtlasiQ8TBP6
PRIDEiQ8TBP6
ProteomicsDBi74037

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
29759, 37 antibodies

The DNASU plasmid repository

More...
DNASUi
55972

Genome annotation databases

EnsembliENST00000341119; ENSP00000344831; ENSG00000075303
GeneIDi55972
KEGGihsa:55972
UCSCiuc003uje.4, human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
55972
DisGeNETi55972
EuPathDBiHostDB:ENSG00000075303.12

GeneCards: human genes, protein and diseases

More...
GeneCardsi
SLC25A40
HGNCiHGNC:29680, SLC25A40
HPAiENSG00000075303, Low tissue specificity
MIMi610821, gene
neXtProtiNX_Q8TBP6
OpenTargetsiENSG00000075303
PharmGKBiPA162403655

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG0761, Eukaryota
GeneTreeiENSGT00940000160249
HOGENOMiCLU_015166_0_0_1
InParanoidiQ8TBP6
KOiK15119
OMAiWPIYEYL
OrthoDBi1007936at2759
PhylomeDBiQ8TBP6
TreeFamiTF314720

Enzyme and pathway databases

PathwayCommonsiQ8TBP6

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
55972, 32 hits in 875 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
SLC25A40, human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
55972
PharosiQ8TBP6, Tdark

Protein Ontology

More...
PROi
PR:Q8TBP6
RNActiQ8TBP6, protein

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSG00000075303, Expressed in adrenal tissue and 212 other tissues
ExpressionAtlasiQ8TBP6, baseline and differential
GenevisibleiQ8TBP6, HS

Family and domain databases

Gene3Di1.50.40.10, 2 hits
InterProiView protein in InterPro
IPR002067, Mit_carrier
IPR018108, Mitochondrial_sb/sol_carrier
IPR023395, Mt_carrier_dom_sf
PfamiView protein in Pfam
PF00153, Mito_carr, 3 hits
PRINTSiPR00926, MITOCARRIER
SUPFAMiSSF103506, SSF103506, 1 hit
PROSITEiView protein in PROSITE
PS50920, SOLCAR, 3 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiS2540_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q8TBP6
Secondary accession number(s): A8K483
, D6W5P6, Q53GB1, Q9UHR1
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 26, 2007
Last sequence update: June 1, 2002
Last modified: August 12, 2020
This is version 142 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human chromosome 7
    Human chromosome 7: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  5. SIMILARITY comments
    Index of protein domains and families
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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