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UniProtKB - Q8TBK6 (ZCH10_HUMAN)

Entry version 138 (23 Feb 2022)
Sequence version 1 (01 Jun 2002)
Previous versions | rss
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Protein

Zinc finger CCHC domain-containing protein 10

Gene

ZCCHC10

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section specifies the position(s) and type(s) of zinc fingers within the protein.<p><a href='/help/zn_fing' target='_top'>More...</a></p>Zinc fingeri43 – 60CCHC-typeAdd BLAST18

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

LigandMetal-binding, Zinc

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...PathwayCommonsi		Q8TBK6

SignaLink: a signaling pathway resource with multi-layered regulatory networks

More...SignaLinki		Q8TBK6

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Zinc finger CCHC domain-containing protein 10
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ZCCHC10
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 5

Organism-specific databases

Human Gene Nomenclature Database

More...HGNCi		HGNC:25954, ZCCHC10

neXtProt; the human protein knowledge platform

More...neXtProti		NX_Q8TBK6

Eukaryotic Pathogen, Vector and Host Database Resources

More...VEuPathDBi		HostDB:ENSG00000155329

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...DisGeNETi		54819

Open Targets

More...OpenTargetsi		ENSG00000155329

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...PharmGKBi		PA134876515

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...Pharosi		Q8TBK6, Tdark

Genetic variation databases

BioMuta curated single-nucleotide variation and disease association database

More...BioMutai		ZCCHC10

Domain mapping of disease mutations (DMDM)

More...DMDMi		84028163

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001509671 – 192Zinc finger CCHC domain-containing protein 10Add BLAST192

Proteomic databases

Encyclopedia of Proteome Dynamics

More...EPDi		Q8TBK6

jPOST - Japan Proteome Standard Repository/Database

More...jPOSTi		Q8TBK6

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...MassIVEi		Q8TBK6

MaxQB - The MaxQuant DataBase

More...MaxQBi		Q8TBK6

PeptideAtlas

More...PeptideAtlasi		Q8TBK6

PRoteomics IDEntifications database

More...PRIDEi		Q8TBK6

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		74024 [Q8TBK6-1]
74025 [Q8TBK6-2]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		Q8TBK6

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		Q8TBK6

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSG00000155329, Expressed in amniotic fluid and 238 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		Q8TBK6, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		Q8TBK6, HS

Organism-specific databases

Human Protein Atlas

More...HPAi		ENSG00000155329, Low tissue specificity

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Hide details
Q8TBK6
With#Exp.IntAct
ANKRD36B - isoform 4 [Q8N2N9-4]3EBI-597063,EBI-12170453
BEND7 - isoform 2 [Q8N7W2-2]3EBI-597063,EBI-10181188
CAVIN1 [Q6NZI2]3EBI-597063,EBI-2559016
CEP63 [Q96MT8]3EBI-597063,EBI-741977
CEP70 [Q8NHQ1]4EBI-597063,EBI-739624
COIL [P38432]3EBI-597063,EBI-945751
DAB1 [O75553]3EBI-597063,EBI-7875264
DACH1 - isoform 2 [Q9UI36-2]3EBI-597063,EBI-10186082
DZIP3 [Q86Y13]6EBI-597063,EBI-948630
ELOA2 [Q8IYF1]3EBI-597063,EBI-741705
EPB41 - isoform 2 [P11171-2]3EBI-597063,EBI-10197451
FAM9B [Q8IZU0]3EBI-597063,EBI-10175124
GKAP1 [Q5VSY0]3EBI-597063,EBI-743722
HMGXB4 [Q9UGU5]5EBI-597063,EBI-7261162
KCTD6 [Q8NC69]3EBI-597063,EBI-2511344
KPNA3 [O00505]3EBI-597063,EBI-358297
LNX1 [Q8TBB1]3EBI-597063,EBI-739832
MAB21L3 [Q8N8X9]3EBI-597063,EBI-10268010
MCRS1 [Q96EZ8]3EBI-597063,EBI-348259
MEOX1 [P50221]3EBI-597063,EBI-2864512
NUDT14 [O95848]3EBI-597063,EBI-536866
PRR13 [Q9NZ81]4EBI-597063,EBI-740924
PSME3 [P61289]7EBI-597063,EBI-355546
PTPN3 [P26045]3EBI-597063,EBI-1047946
RBM39 [Q14498]4EBI-597063,EBI-395290
RBM39 - isoform 3 [Q14498-3]3EBI-597063,EBI-6654703
RPL22 [P35268]3EBI-597063,EBI-354533
SDCBP [O00560]3EBI-597063,EBI-727004
SDCBP2 [Q9H190]4EBI-597063,EBI-742426
SF3B4 [Q15427]3EBI-597063,EBI-348469
SFMBT1 [Q9UHJ3]6EBI-597063,EBI-747398
SIAH1 [Q8IUQ4]3EBI-597063,EBI-747107
STAC3 [Q96MF2]7EBI-597063,EBI-745680
STX11 [O75558]4EBI-597063,EBI-714135
TFCP2 [Q12800]4EBI-597063,EBI-717422
THAP1 [Q9NVV9]10EBI-597063,EBI-741515
ZBTB14 [O43829]3EBI-597063,EBI-10176632
ZBTB8A [Q96BR9]3EBI-597063,EBI-742740
ankX [Q5ZXN6] from Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513).2EBI-597063,EBI-26359852

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		120174, 232 interactors

Protein interaction database and analysis system

More...IntActi		Q8TBK6, 65 interactors

Molecular INTeraction database

More...MINTi		Q8TBK6

STRING: functional protein association networks

More...STRINGi		9606.ENSP00000423276

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		Q8TBK6, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni89 – 192DisorderedSequence analysisAdd BLAST104

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi107 – 180Polar residuesSequence analysisAdd BLAST74

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri43 – 60CCHC-typeAdd BLAST18

Keywords - Domaini

Zinc-finger

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG3116, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00730000111200

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_111178_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q8TBK6

Identification of Orthologs from Complete Genome Data

More...OMAi		TGHFTYQ

Database of Orthologous Groups

More...OrthoDBi		1638633at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		Q8TBK6

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR039715, ZCCHC10
IPR036875, Znf_CCHC_sf

The PANTHER Classification System

More...PANTHERi		PTHR13491, PTHR13491, 1 hit

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF57756, SSF57756, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 5 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q8TBK6-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <p><strong>What is the canonical sequence?</strong><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MATPMHRLIA RRQAFDTELQ PVKTFWILIQ PSIVISEANK QHVRCQKCLE 
        60         70         80         90        100
FGHWTYECTG KRKYLHRPSR TAELKKALKE KENRLLLQQS IGETNVERKA 
       110        120        130        140        150
KKKRSKSVTS SSSSSSDSSA SDSSSESEET STSSSSEDSD TDESSSSSSS 
       160        170        180        190 
SASSTTSSSS SDSDSDSSSS SSSSTSTDSS SDDEPPKKKK KK
Length:192
Mass (Da):20,967
Last modified:June 1, 2002 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iE600FD109936B53E
GO
Isoform 2 (identifier: Q8TBK6-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     15-36: Missing.

Show »
Length:170
Mass (Da):18,410
Checksum:iF1864E485E59C931
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 5 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
G3XAM1G3XAM1_HUMAN
Zinc finger CCHC domain-containing ...
ZCCHC10 hCG_1639963
156Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
B3KVL5B3KVL5_HUMAN
Zinc finger CCHC domain-containing ...
ZCCHC10 hCG_1639963
186Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
D6R9G7D6R9G7_HUMAN
Zinc finger CCHC domain-containing ...
ZCCHC10
114Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
D6RHC2D6RHC2_HUMAN
Zinc finger CCHC domain-containing ...
ZCCHC10 hCG_1639963
92Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
D6RIV3D6RIV3_HUMAN
Zinc finger CCHC domain-containing ...
ZCCHC10
72Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_01371815 – 36Missing in isoform 2. 2 PublicationsAdd BLAST22

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AK000101 mRNA Translation: BAA90946.1
BC005211 mRNA Translation: AAH05211.1
BC022443 mRNA Translation: AAH22443.1

The Consensus CDS (CCDS) project

More...CCDSi		CCDS4165.1 [Q8TBK6-2]
CCDS75301.1 [Q8TBK6-1]

NCBI Reference Sequences

More...RefSeqi		NP_001287745.1, NM_001300816.2 [Q8TBK6-1]
NP_001287746.1, NM_001300817.2
NP_001287747.1, NM_001300818.2
NP_001287748.1, NM_001300819.2
NP_001287751.1, NM_001300822.2
NP_001295056.1, NM_001308127.1
NP_001295057.1, NM_001308128.1
NP_001295058.1, NM_001308129.1
NP_001295059.1, NM_001308130.1
NP_060135.1, NM_017665.3 [Q8TBK6-2]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000324170; ENSP00000324274; ENSG00000155329 [Q8TBK6-2]
ENST00000509437; ENSP00000423276; ENSG00000155329

Database of genes from NCBI RefSeq genomes

More...GeneIDi		54819

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hsa:54819

Matched Annotation from NCBI and EMBL-EBI (MANE) - Phase one

More...MANE-Selecti		ENST00000509437.6; ENSP00000423276.1; NM_001300816.3; NP_001287745.1

UCSC genome browser

More...UCSCi		uc003kyg.4, human [Q8TBK6-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK000101 mRNA Translation: BAA90946.1
BC005211 mRNA Translation: AAH05211.1
BC022443 mRNA Translation: AAH22443.1
CCDSiCCDS4165.1 [Q8TBK6-2]
CCDS75301.1 [Q8TBK6-1]
RefSeqiNP_001287745.1, NM_001300816.2 [Q8TBK6-1]
NP_001287746.1, NM_001300817.2
NP_001287747.1, NM_001300818.2
NP_001287748.1, NM_001300819.2
NP_001287751.1, NM_001300822.2
NP_001295056.1, NM_001308127.1
NP_001295057.1, NM_001308128.1
NP_001295058.1, NM_001308129.1
NP_001295059.1, NM_001308130.1
NP_060135.1, NM_017665.3 [Q8TBK6-2]

3D structure databases

Database of comparative protein structure models

More...ModBasei		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

Protein-protein interaction databases

BioGRIDi120174, 232 interactors
IntActiQ8TBK6, 65 interactors
MINTiQ8TBK6
STRINGi9606.ENSP00000423276

PTM databases

iPTMnetiQ8TBK6
PhosphoSitePlusiQ8TBK6

Genetic variation databases

BioMutaiZCCHC10
DMDMi84028163

Proteomic databases

EPDiQ8TBK6
jPOSTiQ8TBK6
MassIVEiQ8TBK6
MaxQBiQ8TBK6
PeptideAtlasiQ8TBK6
PRIDEiQ8TBK6
ProteomicsDBi74024 [Q8TBK6-1]
74025 [Q8TBK6-2]

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...Antibodypediai		26217, 30 antibodies from 11 providers

The DNASU plasmid repository

More...DNASUi		54819

Genome annotation databases

EnsembliENST00000324170; ENSP00000324274; ENSG00000155329 [Q8TBK6-2]
ENST00000509437; ENSP00000423276; ENSG00000155329
GeneIDi54819
KEGGihsa:54819
MANE-SelectiENST00000509437.6; ENSP00000423276.1; NM_001300816.3; NP_001287745.1
UCSCiuc003kyg.4, human [Q8TBK6-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		54819
DisGeNETi54819

GeneCards: human genes, protein and diseases

More...GeneCardsi		ZCCHC10
HGNCiHGNC:25954, ZCCHC10
HPAiENSG00000155329, Low tissue specificity
neXtProtiNX_Q8TBK6
OpenTargetsiENSG00000155329
PharmGKBiPA134876515
VEuPathDBiHostDB:ENSG00000155329

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

eggNOGiKOG3116, Eukaryota
GeneTreeiENSGT00730000111200
HOGENOMiCLU_111178_0_0_1
InParanoidiQ8TBK6
OMAiTGHFTYQ
OrthoDBi1638633at2759
PhylomeDBiQ8TBK6

Enzyme and pathway databases

PathwayCommonsiQ8TBK6
SignaLinkiQ8TBK6

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		54819, 10 hits in 1044 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		ZCCHC10, human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		54819
PharosiQ8TBK6, Tdark

Protein Ontology

More...PROi		PR:Q8TBK6
RNActiQ8TBK6, protein

Gene expression databases

BgeeiENSG00000155329, Expressed in amniotic fluid and 238 other tissues
ExpressionAtlasiQ8TBK6, baseline and differential
GenevisibleiQ8TBK6, HS

Family and domain databases

InterProiView protein in InterPro
IPR039715, ZCCHC10
IPR036875, Znf_CCHC_sf
PANTHERiPTHR13491, PTHR13491, 1 hit
SUPFAMiSSF57756, SSF57756, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiZCH10_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q8TBK6
Secondary accession number(s): Q9NXR4
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 10, 2005
Last sequence update: June 1, 2002
Last modified: February 23, 2022
This is version 138 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human chromosome 5
    Human chromosome 5: entries, gene names and cross-references to MIM
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