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Entry version 127 (12 Aug 2020)
Sequence version 2 (04 Nov 2008)
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Protein

Fibronectin type III domain-containing protein 9

Gene

FNDC9

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Caution

Encoded in intron of the gene CYFIP2 (opposite strand).Curated

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...
PathwayCommonsi
Q8TBE3

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Fibronectin type III domain-containing protein 9
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:FNDC9
Synonyms:C5orf40
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 5

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000172568.4

Human Gene Nomenclature Database

More...
HGNCi
HGNC:33547, FNDC9

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q8TBE3

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei113 – 133HelicalSequence analysisAdd BLAST21

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
408263

Open Targets

More...
OpenTargetsi
ENSG00000172568

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA162380178

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q8TBE3, Tdark

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
FNDC9

Domain mapping of disease mutations (DMDM)

More...
DMDMi
212276424

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002994091 – 224Fibronectin type III domain-containing protein 9Add BLAST224

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q8TBE3

PRoteomics IDEntifications database

More...
PRIDEi
Q8TBE3

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
74000

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q8TBE3

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q8TBE3

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000172568, Expressed in cerebellar vermis and 94 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q8TBE3, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q8TBE3, HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
ENSG00000172568, Group enriched (adrenal gland, brain, pituitary gland)

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Q8TBE3
With#Exp.IntAct
ADIPOQ [Q15848]3EBI-12142257,EBI-10827839
AGTRAP - isoform 2 [Q6RW13-2]3EBI-12142257,EBI-11522760
AIG1 - isoform 2 [Q9NVV5-2]3EBI-12142257,EBI-11957045
AOC3 [Q16853]3EBI-12142257,EBI-3921628
AQP1 [P29972]3EBI-12142257,EBI-745213
ASGR1 [P07306]3EBI-12142257,EBI-1172335
ATP6V0C [P27449]3EBI-12142257,EBI-721179
ATXN1 [P54253]3EBI-12142257,EBI-930964
BMP10 [O95393]3EBI-12142257,EBI-3922513
C1QL4 [Q86Z23]3EBI-12142257,EBI-12062109
CACNG1 [Q06432]3EBI-12142257,EBI-9686780
CD302 [Q8IX05]3EBI-12142257,EBI-14259393
CLDN1 [O95832]3EBI-12142257,EBI-723889
CLDN11 [O75508]3EBI-12142257,EBI-12820543
CLDN19 - isoform 2 [Q8N6F1-2]3EBI-12142257,EBI-12256978
CLEC1A [Q8NC01]3EBI-12142257,EBI-11996768
CLEC2D - isoform 2 [Q9UHP7-3]3EBI-12142257,EBI-11749983
CLEC7A - isoform 6 [Q9BXN2-6]3EBI-12142257,EBI-11989440
CLN6 [Q9NWW5]3EBI-12142257,EBI-6165897
CLRN2 [A0PK11]3EBI-12142257,EBI-12813623
CMTM5 - isoform 2 [Q96DZ9-2]3EBI-12142257,EBI-11522780
CNIH3 [Q8TBE1]3EBI-12142257,EBI-12208021
COL8A2 [Q4VAQ0]3EBI-12142257,EBI-10241815
CXCL9 [Q07325]3EBI-12142257,EBI-3911467
CYB5B [O43169]3EBI-12142257,EBI-1058710
DEFB132 [Q7Z7B7]3EBI-12142257,EBI-17250048
DOLK [Q9UPQ8]3EBI-12142257,EBI-8645574
EDDM3B [P56851]3EBI-12142257,EBI-10215665
EMP3 [P54852]3EBI-12142257,EBI-3907816
ENTPD3 - isoform 2 [O75355-2]3EBI-12142257,EBI-12279764
ERMP1 [Q7Z2K6]3EBI-12142257,EBI-10976398
EXTL1 [Q92935]3EBI-12142257,EBI-1760167
FAM3C [Q92520]3EBI-12142257,EBI-2876774
GALNT15 [Q8N3T1]3EBI-12142257,EBI-3925203
GCNT2 - isoform C [Q8N0V5-3]3EBI-12142257,EBI-17248158
HHATL [Q9HCP6]3EBI-12142257,EBI-5916693
IGFBP5 [P24593]3EBI-12142257,EBI-720480
ITM2A [O43736]3EBI-12142257,EBI-2431769
ITM2C - isoform 3 [Q9NQX7-3]3EBI-12142257,EBI-12811565
JAGN1 [Q8N5M9]3EBI-12142257,EBI-10266796
KRTCAP3 [Q53RY4]3EBI-12142257,EBI-12383540
LHFPL5 [Q8TAF8]3EBI-12142257,EBI-2820517
LPAR3 [Q9UBY5]3EBI-12142257,EBI-12033434
MAL [P21145]3EBI-12142257,EBI-3932027
MALL [Q13021]3EBI-12142257,EBI-750078
MOSPD3 [O75425]3EBI-12142257,EBI-12179105
MYADM [Q96S97]3EBI-12142257,EBI-13301517
NINJ1 [Q92982]3EBI-12142257,EBI-2802124
NINJ2 [Q9NZG7]3EBI-12142257,EBI-10317425
NKG7 [Q16617]3EBI-12142257,EBI-3919611
NSG1 [P42857]3EBI-12142257,EBI-6380741
OLFM4 [Q6UX06]3EBI-12142257,EBI-2804156
PGA4 [P0DJD7]3EBI-12142257,EBI-12957629
PGAP2 - isoform 5 [Q9UHJ9-5]3EBI-12142257,EBI-12092917
PLLP [Q9Y342]3EBI-12142257,EBI-3919291
PLN [P26678]3EBI-12142257,EBI-692836
PLP1 - isoform DM-20 [P60201-2]3EBI-12142257,EBI-12188331
PLP2 [Q04941]3EBI-12142257,EBI-608347
PLPP6 [Q8IY26]3EBI-12142257,EBI-11721828
PPGB [Q59EV6]3EBI-12142257,EBI-14210385
PROKR2 [Q8NFJ6]3EBI-12142257,EBI-12902928
RPRM [Q9NS64]3EBI-12142257,EBI-1052363
SEC22B [O75396]3EBI-12142257,EBI-1058865
SERP2 [Q8N6R1]3EBI-12142257,EBI-749270
SFTPC [P11686]3EBI-12142257,EBI-10197617
SLC30A8 [Q8IWU4]3EBI-12142257,EBI-10262251
SLC35A1 [P78382]3EBI-12142257,EBI-12870360
SLC41A2 [Q96JW4]3EBI-12142257,EBI-10290130
SMIM1 [B2RUZ4]3EBI-12142257,EBI-12188413
SMIM3 [Q9BZL3]3EBI-12142257,EBI-741850
ST6GAL2 - isoform 2 [Q96JF0-2]3EBI-12142257,EBI-12908338
STX8 [Q9UNK0]3EBI-12142257,EBI-727240
TMEM100 [Q9NV29]3EBI-12142257,EBI-8644968
TMEM140 [Q9NV12]3EBI-12142257,EBI-2844246
TMEM182 [Q6ZP80]3EBI-12142257,EBI-10255122
TMEM254 [Q8TBM7]3EBI-12142257,EBI-11956809
TMEM60 [Q9H2L4]3EBI-12142257,EBI-2852148
TMEM79 [Q9BSE2]3EBI-12142257,EBI-8649725
TMEM86A [Q8N2M4]3EBI-12142257,EBI-12015604
TMPRSS4 [Q9NRS4]3EBI-12142257,EBI-10313040
TNF [P01375]3EBI-12142257,EBI-359977
TREX1 - isoform 1 [Q9NSU2-1]3EBI-12142257,EBI-16746122
TSPO2 [Q5TGU0]3EBI-12142257,EBI-12195249
TTMP [Q5BVD1]3EBI-12142257,EBI-10243654
TUSC5 [A5PKU2]3EBI-12142257,EBI-11988865
TWSG1 [Q9GZX9]3EBI-12142257,EBI-10304067
UBIAD1 [Q9Y5Z9]3EBI-12142257,EBI-2819725
UPK1B [O75841]3EBI-12142257,EBI-12237619
UPK2 [O00526]3EBI-12142257,EBI-10179682
VAMP5 [O95183]3EBI-12142257,EBI-10191195
VSTM1 - isoform 3 [Q6UX27-3]3EBI-12142257,EBI-12190699
ZDHHC22 [Q8N966]3EBI-12142257,EBI-10268111
ZFPL1 [O95159]3EBI-12142257,EBI-718439

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
135924, 1 interactor

Protein interaction database and analysis system

More...
IntActi
Q8TBE3, 93 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000310594

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q8TBE3, protein

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini1 – 101Fibronectin type-IIIPROSITE-ProRule annotationAdd BLAST101

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG502RYGM, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000013517

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q8TBE3

Identification of Orthologs from Complete Genome Data

More...
OMAi
HVMYRPN

Database of Orthologous Groups

More...
OrthoDBi
1299680at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q8TBE3

TreeFam database of animal gene trees

More...
TreeFami
TF335961

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00063, FN3, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.60.40.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR003961, FN3_dom
IPR036116, FN3_sf
IPR013783, Ig-like_fold

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF49265, SSF49265, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50853, FN3, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

Q8TBE3-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MNIEVGNISY TGAIISWSSS EPCLEDYYHI MYRPNWNSIF SGYLRYSFHH
60 70 80 90 100
EEKVPRTISS VVLEHLAPST LYFLCISCKK AAFPYRHYCT MFHTLDKSPL
110 120 130 140 150
APGSSLVDPQ ISLWVLMAIL LACFTAVLAF ICLQFWCVRC HEPRWSYRAG
160 170 180 190 200
HMEEANGLVR WPEEAPDLGQ REEDLQGLPL VEMPRKNSRD GAELDPEANQ
210 220
DAPDAGALQR GGGDPPAILP HCGE
Length:224
Mass (Da):25,275
Last modified:November 4, 2008 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i54D6E1C3BD28101F
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
E5RIJ1E5RIJ1_HUMAN
Fibronectin type III domain-contain...
FNDC9
180Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_04713850H → N1 PublicationCorresponds to variant dbSNP:rs17852104Ensembl.1
Natural variantiVAR_047139138V → I. Corresponds to variant dbSNP:rs10037485Ensembl.1
Natural variantiVAR_047140166P → A. Corresponds to variant dbSNP:rs17054522Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AK289701 mRNA Translation: BAF82390.1
AC016571 Genomic DNA No translation available.
CH471062 Genomic DNA Translation: EAW61607.1
BC022570 mRNA Translation: AAH22570.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS4337.1

NCBI Reference Sequences

More...
RefSeqi
NP_001001343.2, NM_001001343.3

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000312349; ENSP00000310594; ENSG00000172568

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
408263

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:408263

UCSC genome browser

More...
UCSCi
uc003lwu.3, human

Keywords - Coding sequence diversityi

Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK289701 mRNA Translation: BAF82390.1
AC016571 Genomic DNA No translation available.
CH471062 Genomic DNA Translation: EAW61607.1
BC022570 mRNA Translation: AAH22570.1
CCDSiCCDS4337.1
RefSeqiNP_001001343.2, NM_001001343.3

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

BioGRIDi135924, 1 interactor
IntActiQ8TBE3, 93 interactors
STRINGi9606.ENSP00000310594

PTM databases

iPTMnetiQ8TBE3
PhosphoSitePlusiQ8TBE3

Polymorphism and mutation databases

BioMutaiFNDC9
DMDMi212276424

Proteomic databases

PaxDbiQ8TBE3
PRIDEiQ8TBE3
ProteomicsDBi74000

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
2636, 34 antibodies

The DNASU plasmid repository

More...
DNASUi
408263

Genome annotation databases

EnsembliENST00000312349; ENSP00000310594; ENSG00000172568
GeneIDi408263
KEGGihsa:408263
UCSCiuc003lwu.3, human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
408263
DisGeNETi408263
EuPathDBiHostDB:ENSG00000172568.4

GeneCards: human genes, protein and diseases

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GeneCardsi
FNDC9
HGNCiHGNC:33547, FNDC9
HPAiENSG00000172568, Group enriched (adrenal gland, brain, pituitary gland)
neXtProtiNX_Q8TBE3
OpenTargetsiENSG00000172568
PharmGKBiPA162380178

GenAtlas: human gene database

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GenAtlasi
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Phylogenomic databases

eggNOGiENOG502RYGM, Eukaryota
GeneTreeiENSGT00390000013517
InParanoidiQ8TBE3
OMAiHVMYRPN
OrthoDBi1299680at2759
PhylomeDBiQ8TBE3
TreeFamiTF335961

Enzyme and pathway databases

PathwayCommonsiQ8TBE3

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

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BioGRID-ORCSi
408263, 4 hits in 864 CRISPR screens

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

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GenomeRNAii
408263
PharosiQ8TBE3, Tdark

Protein Ontology

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PROi
PR:Q8TBE3
RNActiQ8TBE3, protein

Gene expression databases

BgeeiENSG00000172568, Expressed in cerebellar vermis and 94 other tissues
ExpressionAtlasiQ8TBE3, baseline and differential
GenevisibleiQ8TBE3, HS

Family and domain databases

CDDicd00063, FN3, 1 hit
Gene3Di2.60.40.10, 1 hit
InterProiView protein in InterPro
IPR003961, FN3_dom
IPR036116, FN3_sf
IPR013783, Ig-like_fold
SUPFAMiSSF49265, SSF49265, 1 hit
PROSITEiView protein in PROSITE
PS50853, FN3, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiFNDC9_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q8TBE3
Secondary accession number(s): A8K0Y6
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 11, 2007
Last sequence update: November 4, 2008
Last modified: August 12, 2020
This is version 127 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  2. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  3. Human chromosome 5
    Human chromosome 5: entries, gene names and cross-references to MIM
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