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UniProtKB - Q8TBE0 (BAHD1_HUMAN)

Entry version 138 (07 Apr 2021)
Sequence version 2 (29 May 2007)
Previous versions | rss
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Protein

Bromo adjacent homology domain-containing 1 protein

Gene

BAHD1

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Heterochromatin protein that acts as a transcription repressor and has the ability to promote the formation of large heterochromatic domains. May act by recruiting heterochromatin proteins such as CBX5 (HP1 alpha), HDAC5 and MBD1. Represses IGF2 expression by binding to its CpG-rich P3 promoter and recruiting heterochromatin proteins. At specific stages of Listeria infection, in complex with TRIM28, corepresses interferon-stimulated genes, including IFNL1, IFNL2 and IFNL3.2 Publications

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionChromatin regulator, Repressor
Biological processTranscription, Transcription regulation

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...PathwayCommonsi		Q8TBE0

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Bromo adjacent homology domain-containing 1 protein
Short name:
BAH domain-containing protein 1
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:BAHD1
Synonyms:KIAA0945
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 15

Organism-specific databases

Human Gene Nomenclature Database

More...HGNCi		HGNC:29153, BAHD1

Online Mendelian Inheritance in Man (OMIM)

More...MIMi		613880, gene

neXtProt; the human protein knowledge platform

More...neXtProti		NX_Q8TBE0

Eukaryotic Pathogen, Vector and Host Database Resources

More...VEuPathDBi		HostDB:ENSG00000140320.11

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Chromosome, Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...DisGeNETi		22893

Open Targets

More...OpenTargetsi		ENSG00000140320

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...PharmGKBi		PA128394592

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...Pharosi		Q8TBE0, Tbio

Genetic variation databases

BioMuta curated single-nucleotide variation and disease association database

More...BioMutai		BAHD1

Domain mapping of disease mutations (DMDM)

More...DMDMi		152040006

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002879181 – 780Bromo adjacent homology domain-containing 1 proteinAdd BLAST780

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei8PhosphoserineCombined sources1
Modified residuei101PhosphoserineCombined sources1
Modified residuei121PhosphoserineCombined sources1
Modified residuei184PhosphoserineCombined sources1
Modified residuei206PhosphoserineCombined sources1
Modified residuei588PhosphothreonineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...EPDi		Q8TBE0

jPOST - Japan Proteome Standard Repository/Database

More...jPOSTi		Q8TBE0

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...MassIVEi		Q8TBE0

MaxQB - The MaxQuant DataBase

More...MaxQBi		Q8TBE0

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		Q8TBE0

PeptideAtlas

More...PeptideAtlasi		Q8TBE0

PRoteomics IDEntifications database

More...PRIDEi		Q8TBE0

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		73996 [Q8TBE0-1]
73997 [Q8TBE0-2]
73998 [Q8TBE0-3]

Consortium for Top Down Proteomics

More...TopDownProteomicsi		Q8TBE0-3 [Q8TBE0-3]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		Q8TBE0

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		Q8TBE0

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSG00000140320, Expressed in right adrenal gland and 236 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		Q8TBE0, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		Q8TBE0, HS

Organism-specific databases

Human Protein Atlas

More...HPAi		ENSG00000140320, Low tissue specificity

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with CBX5 (HP1 alpha), HDAC5, MBD1 and SP1.

Forms a transcription silencing complex with at least CBX3 (HP1 gamma), HDAC1, HDAC2 and TRIM28.

Interacts with L.monocytogenes LntA; this interaction, occurring at a late Listeria infection stage, relieves transcription repression, mostly that of interferon-stimulated genes.

2 Publications

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Q8TBE0
With#Exp.IntAct
ARID5A [Q03989]3EBI-742750,EBI-948603
ATN1 [Q86V38]3EBI-742750,EBI-11954292
BACH2 [Q9BYV9]3EBI-742750,EBI-1642333
BAG6 - isoform 2 [P46379-2]3EBI-742750,EBI-10988864
CALCOCO2 [Q13137]3EBI-742750,EBI-739580
CARD10 [Q9BWT7]3EBI-742750,EBI-3866279
CBX1 [P83916]3EBI-742750,EBI-78129
CBX5 [P45973]3EBI-742750,EBI-78219
CHAT - isoform R [P28329-3]3EBI-742750,EBI-25837549
COL26A1 - isoform 2 [Q96A83-2]3EBI-742750,EBI-21553822
CRYAA2 [A0A140G945]3EBI-742750,EBI-25838900
CYSRT1 [A8MQ03]3EBI-742750,EBI-3867333
DR1 [Q01658]3EBI-742750,EBI-750300
DVL3 [Q92997]4EBI-742750,EBI-739789
EIF2S3 [P41091]3EBI-742750,EBI-1054228
ERN1 - isoform 2 [O75460-2]3EBI-742750,EBI-25852368
FGFR3 [P22607]3EBI-742750,EBI-348399
FKBP1A [Q0VDC6]3EBI-742750,EBI-10226858
GFAP [P14136]3EBI-742750,EBI-744302
GIPC1 - isoform 2 [O14908-2]3EBI-742750,EBI-25913156
GOLGA2 [Q08379]3EBI-742750,EBI-618309
GOLGA6L9 [A6NEM1]3EBI-742750,EBI-5916454
GSN [P06396]3EBI-742750,EBI-351506
GTF2B [Q00403]3EBI-742750,EBI-389564
GTF3C3 [Q9Y5Q9]3EBI-742750,EBI-1054873
HOXA1 [P49639]3EBI-742750,EBI-740785
HSPA2 [P54652]3EBI-742750,EBI-356991
KHDRBS2 [Q5VWX1]3EBI-742750,EBI-742808
KHDRBS3 [O75525]4EBI-742750,EBI-722504
KLF11 [O14901]3EBI-742750,EBI-948266
KLK6 [Q92876]3EBI-742750,EBI-2432309
KPNA3 [O00505]3EBI-742750,EBI-358297
KRT40 [Q6A162]3EBI-742750,EBI-10171697
KRTAP10-7 [P60409]3EBI-742750,EBI-10172290
KRTAP10-8 [P60410]3EBI-742750,EBI-10171774
KRTAP19-1 [Q8IUB9]3EBI-742750,EBI-12811111
KRTAP19-7 [Q3SYF9]3EBI-742750,EBI-10241353
KRTAP2-4 [Q9BYR9]3EBI-742750,EBI-14065470
KRTAP6-1 [Q3LI64]3EBI-742750,EBI-12111050
LASP1 - isoform 2 [Q14847-2]3EBI-742750,EBI-9088686
LMNA [P02545]3EBI-742750,EBI-351935
LZTS2 [Q9BRK4]7EBI-742750,EBI-741037
M1AP [Q8TC57]3EBI-742750,EBI-748182
MDFI [Q99750]7EBI-742750,EBI-724076
MID2 - isoform 2 [Q9UJV3-2]3EBI-742750,EBI-10172526
NUP58 [Q9BVL2]3EBI-742750,EBI-2811583
PICK1 [Q9NRD5]3EBI-742750,EBI-79165
PRDM14 [Q9GZV8]3EBI-742750,EBI-3957793
RBM10 [P98175]3EBI-742750,EBI-721525
SERPINH1 [P50454]3EBI-742750,EBI-350723
SPRED1 [Q7Z699]3EBI-742750,EBI-5235340
TARDBP [Q13148]6EBI-742750,EBI-372899
TGFBR2 [P37173]3EBI-742750,EBI-296151
TLE5 [Q08117]3EBI-742750,EBI-717810
TLE5 - isoform 2 [Q08117-2]3EBI-742750,EBI-11741437
TNS2 [Q63HR2]3EBI-742750,EBI-949753
TRAF2 [Q12933]4EBI-742750,EBI-355744
TRAF4 [Q9BUZ4]6EBI-742750,EBI-3650647
UBQLN1 [Q9UMX0]3EBI-742750,EBI-741480
ZNF275 [Q9NSD4]3EBI-742750,EBI-17263125
ZNF317 [Q96PQ6]3EBI-742750,EBI-1210473
ZNF408 [Q9H9D4]3EBI-742750,EBI-347633
ZNF526 [Q8TF50]3EBI-742750,EBI-11035148
ZNF837 [Q96EG3]3EBI-742750,EBI-11962574
ZRANB1 [Q9UGI0]3EBI-742750,EBI-527853

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		116558, 56 interactors

Protein interaction database and analysis system

More...IntActi		Q8TBE0, 73 interactors

Molecular INTeraction database

More...MINTi		Q8TBE0

STRING: functional protein association networks

More...STRINGi		9606.ENSP00000396976

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		Q8TBE0, protein

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini624 – 779BAHPROSITE-ProRule annotationAdd BLAST156

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi239 – 361Pro-richAdd BLAST123
Compositional biasi556 – 587Arg-richAdd BLAST32

<p>This subsection of the 'Family and domains' section provides general information on the biological role of a domain. The term 'domain' is intended here in its wide acceptation, it may be a structural domain, a transmembrane region or a functional domain. Several domains are described in this subsection.<p><a href='/help/domain_cc' target='_top'>More...</a></p>Domaini

The BAH domain is required for localization at H3K27me3.1 Publication

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG1886, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00390000003967

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_019093_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q8TBE0

Identification of Orthologs from Complete Genome Data

More...OMAi		PRPKWAK

Database of Orthologous Groups

More...OrthoDBi		11077at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		Q8TBE0

TreeFam database of animal gene trees

More...TreeFami		TF350135

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR001025, BAH_dom

Pfam protein domain database

More...Pfami		View protein in Pfam
PF01426, BAH, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00439, BAH, 1 hit

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS51038, BAH, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (3)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 3 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform. This section is only present in reviewed entries, i.e. in UniProtKB/Swiss-Prot.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket
Isoform 1 (identifier: Q8TBE0-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MTHTRRKSLP MLSSGLTGRR EPLQMEDSNM EQGVEGVEPG MPESPGHLTG 
        60         70         80         90        100
RRKNYPLRKR PLVPEKPKAC KVLLTRLENV AGPRSADEAD ELPPDLPKPP 
       110        120        130        140        150
SPAPSSEDPG LAQPRKRRLA SLNAEALNNL LLEREDTSSL AGTRRSRAGD 
       160        170        180        190        200
PHRSRDRDRA TGGWSSSKKR PRLGDLGGGS RDLSPEPAPD EGPRRDGDPA 
       210        220        230        240        250
PKRLASLNAA AFLKLSQERE LPLRLPRAHA EVDGRSTEPP APKAPRPKWP 
       260        270        280        290        300
KVNGKNYPKA WQGASSGEAA GPPGWQGCPD EPWPSATPCG PSVQPSHQPL 
       310        320        330        340        350
SKALESPLGL RPHLPLLMGG QAALKPEPGR PGEESPAPKQ ELHQPSFPTP 
       360        370        380        390        400
QLSPLPMPGN PADYNGLCVG PELTALGSFY LYCGQEGLQC GGYSPCPMLP 
       410        420        430        440        450
EGKLSPVAAP HEEGLLLAPS SVPSGTPFQH PPWGSSRYCS SEDTGVNGYS 
       460        470        480        490        500
ICGVLPLSVT HAGTTCGGCP YKMPFAAEGC RSLGQLEFPL PEAGHPASPA 
       510        520        530        540        550
HPLLGCPVPS VPPAAEPVPH LQTPTSEPQT VARACPQSAK PPSGSKSGLR 
       560        570        580        590        600
TGSSCRHTAR SKAARRPSHP KQPRVQRPRP RRRRRRRTNG WVPVGAACEK 
       610        620        630        640        650
AVYVLDEPEP AIRKSYQAVE RHGETIRVRD TVLLKSGPRK TSTPYVAKIS 
       660        670        680        690        700
ALWENPESGE LMMSLLWYYR PEHLQGGRSP SMHEPLQNEV FASRHQDQNS 
       710        720        730        740        750
VACIEEKCYV LTFAEYCRFC AMAKRRGEGL PSRKTALVPP SADYSTPPHR 
       760        770        780
TVPEDTDPEL VFLCRHVYDF RHGRILKNPQ
Length:780
Mass (Da):84,652
Last modified:May 29, 2007 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iDDCAA05DFAA6D982
GO
Isoform 2 (identifier: Q8TBE0-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     478-478: Missing.

Show »
Length:779
Mass (Da):84,523
Checksum:i025D321FEB463C3B
GO
Isoform 3 (identifier: Q8TBE0-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     685-687: Missing.

Show »
Length:777
Mass (Da):84,314
Checksum:iBFBD1A288566FFA1
GO

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence BAA76789 differs from that shown. Reason: Erroneous initiation. Extended N-terminus.Curated

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_03235926E → G. Corresponds to variant dbSNP:rs3743143Ensembl.1
Natural variantiVAR_032360182D → H1 PublicationCorresponds to variant dbSNP:rs17856679Ensembl.1
Natural variantiVAR_032361298Q → K3 PublicationsCorresponds to variant dbSNP:rs3803357Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_025623478Missing in isoform 2. 1 Publication1
Alternative sequenceiVSP_025624685 – 687Missing in isoform 3. 1 Publication3

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AB023162 mRNA Translation: BAA76789.2 Different initiation.
BC022782 mRNA Translation: AAH22782.1
AC013356 Genomic DNA No translation available.
AL833923 mRNA Translation: CAD38779.1

The Consensus CDS (CCDS) project

More...CCDSi		CCDS10058.1 [Q8TBE0-1]
CCDS73705.1 [Q8TBE0-2]

NCBI Reference Sequences

More...RefSeqi		NP_001288061.1, NM_001301132.1 [Q8TBE0-2]
NP_055767.3, NM_014952.4 [Q8TBE0-1]
XP_011519671.1, XM_011521369.2 [Q8TBE0-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000416165; ENSP00000396976; ENSG00000140320 [Q8TBE0-1]
ENST00000560846; ENSP00000454101; ENSG00000140320 [Q8TBE0-3]
ENST00000561234; ENSP00000454150; ENSG00000140320 [Q8TBE0-2]

Database of genes from NCBI RefSeq genomes

More...GeneIDi		22893

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hsa:22893

UCSC genome browser

More...UCSCi		uc001zlt.3, human [Q8TBE0-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB023162 mRNA Translation: BAA76789.2 Different initiation.
BC022782 mRNA Translation: AAH22782.1
AC013356 Genomic DNA No translation available.
AL833923 mRNA Translation: CAD38779.1
CCDSiCCDS10058.1 [Q8TBE0-1]
CCDS73705.1 [Q8TBE0-2]
RefSeqiNP_001288061.1, NM_001301132.1 [Q8TBE0-2]
NP_055767.3, NM_014952.4 [Q8TBE0-1]
XP_011519671.1, XM_011521369.2 [Q8TBE0-1]

3D structure databases

Database of comparative protein structure models

More...ModBasei		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

Protein-protein interaction databases

BioGRIDi116558, 56 interactors
IntActiQ8TBE0, 73 interactors
MINTiQ8TBE0
STRINGi9606.ENSP00000396976

PTM databases

iPTMnetiQ8TBE0
PhosphoSitePlusiQ8TBE0

Genetic variation databases

BioMutaiBAHD1
DMDMi152040006

Proteomic databases

EPDiQ8TBE0
jPOSTiQ8TBE0
MassIVEiQ8TBE0
MaxQBiQ8TBE0
PaxDbiQ8TBE0
PeptideAtlasiQ8TBE0
PRIDEiQ8TBE0
ProteomicsDBi73996 [Q8TBE0-1]
73997 [Q8TBE0-2]
73998 [Q8TBE0-3]
TopDownProteomicsiQ8TBE0-3 [Q8TBE0-3]

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...Antibodypediai		23102, 72 antibodies

The DNASU plasmid repository

More...DNASUi		22893

Genome annotation databases

EnsembliENST00000416165; ENSP00000396976; ENSG00000140320 [Q8TBE0-1]
ENST00000560846; ENSP00000454101; ENSG00000140320 [Q8TBE0-3]
ENST00000561234; ENSP00000454150; ENSG00000140320 [Q8TBE0-2]
GeneIDi22893
KEGGihsa:22893
UCSCiuc001zlt.3, human [Q8TBE0-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		22893
DisGeNETi22893

GeneCards: human genes, protein and diseases

More...GeneCardsi		BAHD1
HGNCiHGNC:29153, BAHD1
HPAiENSG00000140320, Low tissue specificity
MIMi613880, gene
neXtProtiNX_Q8TBE0
OpenTargetsiENSG00000140320
PharmGKBiPA128394592
VEuPathDBiHostDB:ENSG00000140320.11

Human Unidentified Gene-Encoded large proteins database

More...HUGEi		Search...

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

eggNOGiKOG1886, Eukaryota
GeneTreeiENSGT00390000003967
HOGENOMiCLU_019093_0_0_1
InParanoidiQ8TBE0
OMAiPRPKWAK
OrthoDBi11077at2759
PhylomeDBiQ8TBE0
TreeFamiTF350135

Enzyme and pathway databases

PathwayCommonsiQ8TBE0

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		22893, 12 hits in 996 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		BAHD1, human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		22893
PharosiQ8TBE0, Tbio

Protein Ontology

More...PROi		PR:Q8TBE0
RNActiQ8TBE0, protein

The Stanford Online Universal Resource for Clones and ESTs

More...SOURCEi		Search...

Gene expression databases

BgeeiENSG00000140320, Expressed in right adrenal gland and 236 other tissues
ExpressionAtlasiQ8TBE0, baseline and differential
GenevisibleiQ8TBE0, HS

Family and domain databases

InterProiView protein in InterPro
IPR001025, BAH_dom
PfamiView protein in Pfam
PF01426, BAH, 1 hit
SMARTiView protein in SMART
SM00439, BAH, 1 hit
PROSITEiView protein in PROSITE
PS51038, BAH, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiBAHD1_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q8TBE0
Secondary accession number(s): Q8NDF7, Q9Y2F4
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 29, 2007
Last sequence update: May 29, 2007
Last modified: April 7, 2021
This is version 138 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human chromosome 15
    Human chromosome 15: entries, gene names and cross-references to MIM
  2. Human entries with genetic variants
    List of human entries with genetic variants
  3. Human variants curated from literature reports
    Index of human variants curated from literature reports
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
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