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1 to 25 of 27  Show
  1. 1
    "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Category: Sequences.
    Tissue: Lung.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 50481 other entries.

  2. 2
    Category: Sequences.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 3288 other entries.

  3. 3
    Category: Expression.
    Source: UniProtKB/Swiss-Prot (reviewed).
  4. 4
    "Recombinant enzymes overexpressed in bacteria show broad catalytic specificity of human cytochrome P450 2W1 and limited activity of human cytochrome P450 2S1."
    Wu Z.L., Sohl C.D., Shimada T., Guengerich F.P.
    Mol. Pharmacol. 69:2007-2014(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION.
    Category: Function.
    Source: UniProtKB/Swiss-Prot (reviewed).
  5. 5
    "Colorectal cancer-specific cytochrome P450 2W1: intracellular localization, glycosylation, and catalytic activity."
    Gomez A., Nekvindova J., Travica S., Lee M.Y., Johansson I., Edler D., Mkrtchian S., Ingelman-Sundberg M.
    Mol. Pharmacol. 78:1004-1011(2010) [PubMed] [Europe PMC] [Abstract]
    Category: Function, Subcellular Location, Pathology & Biotech, PTM / Processing.
    Source: UniProtKB/Swiss-Prot (reviewed).
  6. 6
    "Bioactivation of aromatic amines by human CYP2W1, an orphan cytochrome P450 enzyme."
    Eun C.Y., Han S., Lim Y.R., Park H.G., Han J.S., Cho K.S., Chun Y.J., Kim D.
    Toxicol. Res. 26:171-175(2010) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Source: UniProtKB/Swiss-Prot (reviewed).
  7. 7
    "Metabolomic analysis and identification of a role for the orphan human cytochrome P450 2W1 in selective oxidation of lysophospholipids."
    Xiao Y., Guengerich F.P.
    J. Lipid Res. 53:1610-1617(2012) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Source: UniProtKB/Swiss-Prot (reviewed).
  8. 8
    "CYP2W1 variant alleles in Caucasians and association of the CYP2W1 G541A (Ala181Thr) polymorphism with increased colorectal cancer risk."
    Gervasini G., de Murillo S.G., Ladero J.M., Agundez J.A.
    Pharmacogenomics 11:919-925(2010) [PubMed] [Europe PMC] [Abstract]
    Cited for: VARIANTS ALA-58; THR-181; ILE-432; HIS-482 AND LEU-488.
    Category: Sequences.
    Source: UniProtKB/Swiss-Prot (reviewed).
  9. 9
    "Enzymatic properties of human CYP2W1 expressed in Escherichia coli."
    Yoshioka H., Kasai N., Ikushiro S., Shinkyo R., Kamakura M., Ohta M., Inouye K., Sakaki T.
    Biochem. Biophys. Res. Commun. 345:169-174(2006) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Annotation: PathwayImported.
    Source: Reactome:R-HSA-211032.

    This publication is mapped to 1 other entry.

  10. 10
    "Expression of CYP2W1 in colon tumors: regulation by gene methylation."
    Gomez A., Karlgren M., Edler D., Bernal M.L., Mkrtchian S., Ingelman-Sundberg M.
    Pharmacogenomics 8:1315-1325(2007) [PubMed] [Europe PMC] [Abstract]
    Annotation: The expression of CYP2W1 is colon tumor-specific and is associated with methylation status of the CYP2W1 gene suggesting a potential causal link between the gene hypomethylation and its enhanced expression.Imported.
    Source: GeneRIF:54905.
  11. 11
    "Genetic polymorphisms and haplotype structures of the human CYP2W1 gene in a Japanese population."
    Hanzawa Y., Sasaki T., Mizugaki M., Ishikawa M., Hiratsuka M.
    Drug Metab. Dispos. 36:349-352(2008) [PubMed] [Europe PMC] [Abstract]
    Annotation: Six single nucleotide polymorphisms of CYP2W1 were identified in a Japanese population; Observational study of genotype prevalence. (HuGE Navigator)Imported.
    Source: GeneRIF:54905.
  12. 12
    "Toward an understanding of the protein interaction network of the human liver."
    Wang J., Huo K., Ma L., Tang L., Li D., Huang X., Yuan Y., Li C., Wang W., Guan W., Chen H., Jin C., Wei J., Zhang W., Yang Y., Liu Q., Zhou Y., Zhang C.
    , Wu Z., Xu W., Zhang Y., Liu T., Yu D., Zhang Y., Chen L., Zhu D., Zhong X., Kang L., Gan X., Yu X., Ma Q., Yan J., Zhou L., Liu Z., Zhu Y., Zhou T., He F., Yang X.
    Mol. Syst. Biol. 7:536-536(2011) [PubMed] [Europe PMC] [Abstract]
    Category: Interaction.
    Source: IntAct:Q8TAV3.

    This publication is mapped to 2554 other entries.

  13. 13
    "CYP2W1, CYP4F11 and CYP8A1 polymorphisms and interaction of CYP2W1 genotypes with risk factors in Mexican women with breast cancer."
    Cardenas-Rodriguez N., Lara-Padilla E., Bandala C., Lopez-Cruz J., Uscanga-Carmona C., Lucio-Monter P.F., Floriano-Sanchez E.
    Asian Pac. J. Cancer Prev. 13:837-846(2012) [PubMed] [Europe PMC] [Abstract]
    Annotation: study did not detect an association between the CYP2W1 4F11 and 8A1 genes polymorphisms and breast cancer risk in a Mexican population; however some clinico-pathological risk factors interact with CYP2W1 genotypes and modifies susceptibility to breast cancerImported.
    Source: GeneRIF:54905.
  14. 14
    "The expression of CYP2W1: a prognostic marker in colon cancer."
    Stenstedt K., Hallstrom M., Johansson I., Ingelman-Sundberg M., Ragnhammar P., Edler D.
    Anticancer Res. 32:3869-3874(2012) [PubMed] [Europe PMC] [Abstract]
    Annotation: Results of the current study were in agreement with those of the previous pilot study and show that higher expression of CYP2W1 seems to be of prognostic value in colon cancer.Imported.
    Source: GeneRIF:54905.
  15. 15
    "CYP2W1 polymorphism: functional aspects and relation to risk for colorectal cancer."
    Stenstedt K., Travica S., Guo J., Barragan I., Pors K., Patterson L., Edler D., Mkrtchian S., Johansson I., Ingelman-Sundberg M.
    Pharmacogenomics 14:1615-1622(2013) [PubMed] [Europe PMC] [Abstract]
    Annotation: No significant differences in the distribution of CYP2W1*1 CYP2W1*2 and CYP2W1*6 alleles were found between CRC patients and controls.Imported.
    Source: GeneRIF:54905.
  16. 16
    "The expression of CYP2W1 in colorectal primary tumors, corresponding lymph node metastases and liver metastases."
    Stenstedt K., Hallstrom M., Ledel F., Ragnhammar P., Ingelman-Sundberg M., Johansson I., Edler D.
    Acta Oncol 53:885-891(2014) [PubMed] [Europe PMC] [Abstract]
    Annotation: High CYP2W1 expression is seen in 26% of primary colorectal tumors and in 48% of corresponding liver metastases.Imported.
    Source: GeneRIF:54905.
  17. 17
    "Prognostic value of CYP2W1 expression in patients with human hepatocellular carcinoma."
    Zhang K., Jiang L., He R., Li B.L., Jia Z., Huang R.H., Mu Y.
    Tumour Biol. 35:7669-7673(2014) [PubMed] [Europe PMC] [Abstract]
    Annotation: CYP2W1 could play an important role in hepatocellular carcinoma (HCC) and might serve as a valuable prognostic marker and potential target for gene therapy in the treatment of HCC.Imported.
    Source: GeneRIF:54905.
  18. 18
    "CYP2W1 is highly expressed in adrenal glands and is positively associated with the response to mitotane in adrenocortical carcinoma."
    Ronchi C.L., Sbiera S., Volante M., Steinhauer S., Scott-Wild V., Altieri B., Kroiss M., Bala M., Papotti M., Deutschbein T., Terzolo M., Fassnacht M., Allolio B.
    PLoS ONE 9:e105855-e105855(2014) [PubMed] [Europe PMC] [Abstract]
    Annotation: CYP2W1 is highly expressed in both normal and neoplastic adrenal glands making it a promising tool for targeted therapy in ACCImported.
    Source: GeneRIF:54905.
  19. 19
    "KRT13, FAIM2 and CYP2W1 mRNA expression in oral squamous cell carcinoma patients with risk habits."
    Hartanto F.K., Karen-Ng L.P., Vincent-Chong V.K., Ismail S.M., Mustafa W.M., Abraham M.T., Tay K.K., Zain R.B.
    Asian Pac. J. Cancer Prev. 16:953-958(2015) [PubMed] [Europe PMC] [Abstract]
    Annotation: Low KRT13 mRNA expression is associated with oral squamous cell carcinoma.Imported.
    Source: GeneRIF:54905.

    This publication is mapped to 5 other entries.

  20. 20
    "Developmental regulation and induction of cytochrome P450 2W1, an enzyme expressed in colon tumors."
    Choong E., Guo J., Persson A., Virding S., Johansson I., Mkrtchian S., Ingelman-Sundberg M.
    PLoS ONE 10:e0122820-e0122820(2015) [PubMed] [Europe PMC] [Abstract]
    Annotation: Results show the developmental expression of CYP2W1 in the GI tract mediated by epigenetic modifications its specific location and regulation by anticancer drugs which can be considered as an adjuvant therapy of colon and hepatic cancers.Imported.
    Source: GeneRIF:54905.

    This publication is mapped to 1 other entry.

  21. 21
    "Novel single nucleotide polymorphisms (SNPs) of CYP2W1 gene in Chinese Uygur and Han populations."
    Qi G.Z., Wang X., Miao X.J., Yin S.J., Ren H., Lou Y.Q., Zhang G.L.
    Drug Metab. Pharmacokinet. 30:449-452(2015) [PubMed] [Europe PMC] [Abstract]
    Annotation: Report novel SNPs of CYP2W1 gene in Chinese Uygur and Han populations.Imported.
    Source: GeneRIF:54905.
  22. 22
    "Membrane topology and search for potential redox partners of colon cancer-specific cytochrome P450 2W1."
    Guo J., Thiess S., Johansson I., Mkrtchian S., Ingelman-Sundberg M.
    FEBS Lett. 590:330-339(2016) [PubMed] [Europe PMC] [Abstract]
    Annotation: Data suggest that canonical cytochrome P-450 reductants (cytochrome P450 reductase; cytochrome b5) cannot serve as electron donors for CYP2W1 a colon tumor-specific enzyme; glycosylation of CYP2W1 at Asn177 is required for full catalytic activity.Imported.
    Source: GeneRIF:54905.
  23. 23
    "The CYP2W1 enzyme: regulation, properties and activation of prodrugs."
    Guo J., Johansson I., Mkrtchian S., Ingelman-Sundberg M.
    Drug Metab. Rev. 48:369-378(2016) [PubMed] [Europe PMC] [Abstract]
    Annotation: summarizes the history distribution polymorphism membrane topology function and possible role in cancer therapy of CYP2W1.Imported.
    Source: GeneRIF:54905.
  24. 24
    "Identification of Genetic Polymorphisms of CYP2W1 in the Three Main Chinese Ethnicities: Han, Tibetan, and Uighur."
    Li Y., Kang X., Yang G., Dai P., Chen C., Wang H.
    Drug Metab. Dispos. 44:1510-1515(2016) [PubMed] [Europe PMC] [Abstract]
    Annotation: showed that the genetic pattern of CYP2W1 is interethnically different among the three Chinese populations and this finding can extend our understanding of population genetics of CYP2W1 in the Chinese populationImported.
    Source: GeneRIF:54905.
  25. 25
    "Human Cytochrome P450 2W1 Is Not Expressed in Adrenal Cortex and Is Only Rarely Expressed in Adrenocortical Carcinomas."
    Nole P., Duijndam B., Stenman A., Juhlin C.C., Kozyra M., Larsson C., Ingelman-Sundberg M., Johansson I.
    PLoS ONE 11:e0162379-e0162379(2016) [PubMed] [Europe PMC] [Abstract]
    Annotation: Normal adrenal tissue lacks CYP2W1 enzyme expression; adrenocortical carcinomas generally do not express the enzyme as well.Imported.
    Source: GeneRIF:54905.
1 to 25 of 27  Show

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