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Entry version 127 (16 Oct 2019)
Sequence version 1 (01 Jun 2002)
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Protein

Protein FAM76A

Gene

FAM76A

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Protein FAM76A
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:FAM76A
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 1

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:28530 FAM76A

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q8TAV0

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

More...
OpenTargetsi
ENSG00000009780

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA142671837

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q8TAV0

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
FAM76A

Domain mapping of disease mutations (DMDM)

More...
DMDMi
74751363

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002457601 – 307Protein FAM76AAdd BLAST307

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q8TAV0

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q8TAV0

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q8TAV0

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q8TAV0

PeptideAtlas

More...
PeptideAtlasi
Q8TAV0

PRoteomics IDEntifications database

More...
PRIDEi
Q8TAV0

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
73922 [Q8TAV0-1]
73923 [Q8TAV0-2]
73924 [Q8TAV0-3]
73925 [Q8TAV0-4]
73926 [Q8TAV0-5]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q8TAV0

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q8TAV0

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000009780 Expressed in 195 organ(s), highest expression level in testis

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q8TAV0 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q8TAV0 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA044762

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
128279, 1 interactor

Protein interaction database and analysis system

More...
IntActi
Q8TAV0, 1 interactor

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili217 – 299Sequence analysisAdd BLAST83

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi147 – 150Poly-Ser4

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the FAM76 family.Curated

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

Coiled coil

Phylogenomic databases

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000160073

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000231316

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q8TAV0

Identification of Orthologs from Complete Genome Data

More...
OMAi
TEYQQEX

Database of Orthologous Groups

More...
OrthoDBi
1061935at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q8TAV0

TreeFam database of animal gene trees

More...
TreeFami
TF313644

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR032017 FAM76
IPR029660 FAM76A

The PANTHER Classification System

More...
PANTHERi
PTHR46176 PTHR46176, 1 hit
PTHR46176:SF2 PTHR46176:SF2, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF16046 FAM76, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (5+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 5 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 5 described isoforms and 2 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q8TAV0-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MAALYACTKC HQRFPFEALS QGQQLCKECR IAHPVVKCTY CRTEYQQESK
60 70 80 90 100
TNTICKKCAQ NVQLYGTPKP CQYCNIIAAF IGNKCQRCTN SEKKYGPPYS
110 120 130 140 150
CEQCKQQCAF DRKDDRKKVD GKLLCWLCTL SYKRVLQKTK EQRKHLSSSS
160 170 180 190 200
RAGHQEKEQY SRLSGGGHYN SQKTLSTSSI QNEIPKKKSK FESITTNGDS
210 220 230 240 250
FSPDLALDSP GTDHFVIIAQ LKEEVATLKK MLHQKDQMIL EKEKKITELK
260 270 280 290 300
ADFQYQESQM RAKMNQMEKT HKEVTEQLQA KNRELLKQAA ALSKSKKSEK

SGAITSP
Length:307
Mass (Da):35,049
Last modified:June 1, 2002 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iC6104F177ADF4AF8
GO
Isoform 2 (identifier: Q8TAV0-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     172-200: Missing.

Note: No experimental confirmation available.
Show »
Length:278
Mass (Da):31,870
Checksum:i887AAA81F82E2E1C
GO
Isoform 3 (identifier: Q8TAV0-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     49-49: S → RLECNGTISAHCNLHLPGSSDSPASSSRVAGITGI

Note: No experimental confirmation available.
Show »
Length:341
Mass (Da):38,453
Checksum:iEF7247FD6F734C3F
GO
Isoform 4 (identifier: Q8TAV0-4) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     49-49: S → RLECNGTISAHCNLHLPGSSDSPASSSRVAGITGI
     172-200: Missing.

Note: No experimental confirmation available.
Show »
Length:312
Mass (Da):35,273
Checksum:i02EBED41A423821E
GO
Isoform 5 (identifier: Q8TAV0-5) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     68-118: Missing.
     172-200: Missing.

Note: No experimental confirmation available.
Show »
Length:227
Mass (Da):25,953
Checksum:i3FA9D47BE8A124D4
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
E9PQL1E9PQL1_HUMAN
Protein FAM76A
FAM76A
288Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
B1AJQ5B1AJQ5_HUMAN
Protein FAM76A
FAM76A
124Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_01977149S → RLECNGTISAHCNLHLPGSS DSPASSSRVAGITGI in isoform 3 and isoform 4. 1 Publication1
Alternative sequenceiVSP_04325068 – 118Missing in isoform 5. 1 PublicationAdd BLAST51
Alternative sequenceiVSP_019772172 – 200Missing in isoform 2, isoform 4 and isoform 5. 2 PublicationsAdd BLAST29

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AL035307 mRNA Translation: CAA22912.1
AL035309 mRNA Translation: CAA22914.1
AK098318 mRNA Translation: BAC05285.1
AK301672 mRNA Translation: BAG63145.1
AL020997 Genomic DNA No translation available.
BC025768 mRNA Translation: AAH25768.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS309.1 [Q8TAV0-1]
CCDS44092.1 [Q8TAV0-3]
CCDS44093.1 [Q8TAV0-4]
CCDS44094.1 [Q8TAV0-2]
CCDS44095.1 [Q8TAV0-5]

NCBI Reference Sequences

More...
RefSeqi
NP_001137384.1, NM_001143912.1 [Q8TAV0-3]
NP_001137385.1, NM_001143913.1 [Q8TAV0-4]
NP_001137386.1, NM_001143914.1 [Q8TAV0-2]
NP_001137387.1, NM_001143915.1 [Q8TAV0-5]
NP_689873.1, NM_152660.2 [Q8TAV0-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000010299; ENSP00000010299; ENSG00000009780 [Q8TAV0-3]
ENST00000234549; ENSP00000234549; ENSG00000009780 [Q8TAV0-4]
ENST00000373949; ENSP00000363060; ENSG00000009780 [Q8TAV0-2]
ENST00000373954; ENSP00000363065; ENSG00000009780 [Q8TAV0-1]
ENST00000419687; ENSP00000395150; ENSG00000009780 [Q8TAV0-5]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
199870

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:199870

UCSC genome browser

More...
UCSCi
uc001boq.4 human [Q8TAV0-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL035307 mRNA Translation: CAA22912.1
AL035309 mRNA Translation: CAA22914.1
AK098318 mRNA Translation: BAC05285.1
AK301672 mRNA Translation: BAG63145.1
AL020997 Genomic DNA No translation available.
BC025768 mRNA Translation: AAH25768.1
CCDSiCCDS309.1 [Q8TAV0-1]
CCDS44092.1 [Q8TAV0-3]
CCDS44093.1 [Q8TAV0-4]
CCDS44094.1 [Q8TAV0-2]
CCDS44095.1 [Q8TAV0-5]
RefSeqiNP_001137384.1, NM_001143912.1 [Q8TAV0-3]
NP_001137385.1, NM_001143913.1 [Q8TAV0-4]
NP_001137386.1, NM_001143914.1 [Q8TAV0-2]
NP_001137387.1, NM_001143915.1 [Q8TAV0-5]
NP_689873.1, NM_152660.2 [Q8TAV0-1]

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

BioGridi128279, 1 interactor
IntActiQ8TAV0, 1 interactor

PTM databases

iPTMnetiQ8TAV0
PhosphoSitePlusiQ8TAV0

Polymorphism and mutation databases

BioMutaiFAM76A
DMDMi74751363

Proteomic databases

EPDiQ8TAV0
jPOSTiQ8TAV0
MassIVEiQ8TAV0
MaxQBiQ8TAV0
PeptideAtlasiQ8TAV0
PRIDEiQ8TAV0
ProteomicsDBi73922 [Q8TAV0-1]
73923 [Q8TAV0-2]
73924 [Q8TAV0-3]
73925 [Q8TAV0-4]
73926 [Q8TAV0-5]

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
199870

Genome annotation databases

EnsembliENST00000010299; ENSP00000010299; ENSG00000009780 [Q8TAV0-3]
ENST00000234549; ENSP00000234549; ENSG00000009780 [Q8TAV0-4]
ENST00000373949; ENSP00000363060; ENSG00000009780 [Q8TAV0-2]
ENST00000373954; ENSP00000363065; ENSG00000009780 [Q8TAV0-1]
ENST00000419687; ENSP00000395150; ENSG00000009780 [Q8TAV0-5]
GeneIDi199870
KEGGihsa:199870
UCSCiuc001boq.4 human [Q8TAV0-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
199870

GeneCards: human genes, protein and diseases

More...
GeneCardsi
FAM76A
HGNCiHGNC:28530 FAM76A
HPAiHPA044762
neXtProtiNX_Q8TAV0
OpenTargetsiENSG00000009780
PharmGKBiPA142671837

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

GeneTreeiENSGT00940000160073
HOGENOMiHOG000231316
InParanoidiQ8TAV0
OMAiTEYQQEX
OrthoDBi1061935at2759
PhylomeDBiQ8TAV0
TreeFamiTF313644

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
FAM76A human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
199870
PharosiQ8TAV0

Protein Ontology

More...
PROi
PR:Q8TAV0

Gene expression databases

BgeeiENSG00000009780 Expressed in 195 organ(s), highest expression level in testis
ExpressionAtlasiQ8TAV0 baseline and differential
GenevisibleiQ8TAV0 HS

Family and domain databases

InterProiView protein in InterPro
IPR032017 FAM76
IPR029660 FAM76A
PANTHERiPTHR46176 PTHR46176, 1 hit
PTHR46176:SF2 PTHR46176:SF2, 1 hit
PfamiView protein in Pfam
PF16046 FAM76, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiFA76A_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q8TAV0
Secondary accession number(s): B4DWT3
, O95565, O95566, Q8N7J5
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 11, 2006
Last sequence update: June 1, 2002
Last modified: October 16, 2019
This is version 127 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 1
    Human chromosome 1: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families
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Main funding by: National Institutes of Health

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