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Entry version 139 (22 Apr 2020)
Sequence version 4 (04 Dec 2007)
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Protein

SUN domain-containing protein 3

Gene

SUN3

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

As a probable component of the LINC (LInker of Nucleoskeleton and Cytoskeleton) complex, involved in the connection between the nuclear lamina and the cytoskeleton. The nucleocytoplasmic interactions established by the LINC complex play an important role in the transmission of mechanical forces across the nuclear envelope and in nuclear movement and positioning. May be involved in nuclear remodeling during sperm head formation in spermatogenenis. A probable SUN3:SYNE1 LINC complex may tether spermatid nuclei to posterior cytoskeletal structures such as the manchette.By similarity

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
SUN domain-containing protein 3
Alternative name(s):
Sad1/unc-84 domain-containing protein 1
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:SUN3
Synonyms:SUNC1
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 7

Organism-specific databases

Human Gene Nomenclature Database

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HGNCi
HGNC:22429 SUN3

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q8TAQ9

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini1 – 47NuclearCuratedAdd BLAST47
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei48 – 64HelicalSequence analysisAdd BLAST17
Topological domaini65 – 357Perinuclear spaceCuratedAdd BLAST293

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Membrane, Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
256979

Open Targets

More...
OpenTargetsi
ENSG00000164744

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA165618375

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q8TAQ9 Tdark

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
SUN3

Domain mapping of disease mutations (DMDM)

More...
DMDMi
162416243

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003122201 – 357SUN domain-containing protein 3Add BLAST357

Proteomic databases

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q8TAQ9

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q8TAQ9

PeptideAtlas

More...
PeptideAtlasi
Q8TAQ9

PRoteomics IDEntifications database

More...
PRIDEi
Q8TAQ9

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
18821
73909 [Q8TAQ9-1]
73910 [Q8TAQ9-2]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q8TAQ9

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q8TAQ9

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000164744 Expressed in right testis and 66 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q8TAQ9 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q8TAQ9 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
ENSG00000164744 Tissue enriched (testis)

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Self-associates.

Interacts with SYNE1 and SPAG4/SUN4. Proposed to form a spermatogenesis-specific LINC complex with SYNE1 during sperm head formation possibly implicating a SUN domain-based heterotrimer with SPAG4/SUN4 associating with SYNE1.

By similarity

GO - Molecular functioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
129187, 1 interactor

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000297325

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q8TAQ9 protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q8TAQ9

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini193 – 354SUNPROSITE-ProRule annotationAdd BLAST162

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili98 – 146Sequence analysisAdd BLAST49

<p>This subsection of the 'Family and domains' section provides general information on the biological role of a domain. The term 'domain' is intended here in its wide acceptation, it may be a structural domain, a transmembrane region or a functional domain. Several domains are described in this subsection.<p><a href='/help/domain_cc' target='_top'>More...</a></p>Domaini

The short coiled coil domain is proposed to be not involved in load-bearing and force transmission from the cytoskeleton but in mere nucleus anchorage instead.

Keywords - Domaini

Coiled coil, Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG2687 Eukaryota
ENOG410YM6S LUCA

Ensembl GeneTree

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GeneTreei
ENSGT00940000161393

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_043737_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q8TAQ9

KEGG Orthology (KO)

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KOi
K21874

Identification of Orthologs from Complete Genome Data

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OMAi
HPNYTCL

Database of Orthologous Groups

More...
OrthoDBi
1569602at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q8TAQ9

TreeFam database of animal gene trees

More...
TreeFami
TF323915

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

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Gene3Di
2.60.120.260, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR008979 Galactose-bd-like_sf
IPR030274 SUN3
IPR012919 SUN_dom

The PANTHER Classification System

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PANTHERi
PTHR12911:SF24 PTHR12911:SF24, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF07738 Sad1_UNC, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51469 SUN, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (3+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 3 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform. This section is only present in reviewed entries, i.e. in UniProtKB/Swiss-Prot.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 3 described isoforms and 4 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q8TAQ9-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MSGKTKARRA AMFFRRCSED ASGSASGNAL LSEDENPDAN GVTRSWKIIL
60 70 80 90 100
STMLTLTFLL VGLLNHQWLK ETDVPQKSRQ LYAIIAEYGS RLYKYQARLR
110 120 130 140 150
MPKEQLELLK KESQNLENNF RQILFLIEQI DVLKALLRDM KDGMDNNHNW
160 170 180 190 200
NTHGDPVEDP DHTEEVSNLV NYVLKKLRED QVEMADYALK SAGASIIEAG
210 220 230 240 250
TSESYKNNKA KLYWHGIGFL NHEMPPDIIL QPDVYPGKCW AFPGSQGHTL
260 270 280 290 300
IKLATKIIPT AVTMEHISEK VSPSGNISSA PKEFSVYGIT KKCEGEEIFL
310 320 330 340 350
GQFIYNKTGT TVQTFELQHA VSEYLLCVKL NIFSNWGHPK YTCLYRFRVH

GTPGKHI
Length:357
Mass (Da):40,503
Last modified:December 4, 2007 - v4
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i5E63D57F1806753B
GO
Isoform 2 (identifier: Q8TAQ9-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-100: Missing.
     287-287: Y → YVQRYMCRFVIQA

Show »
Length:269
Mass (Da):30,703
Checksum:i57908C8B09119E5D
GO
Isoform 3 (identifier: Q8TAQ9-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     2-61: SGKTKARRAA...TMLTLTFLLV → EDYSKYNAYT...ASASRVAGTT

Show »
Length:345
Mass (Da):39,079
Checksum:i712063DFF09C7F05
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
F8WDT4F8WDT4_HUMAN
SUN domain-containing protein 3
SUN3
89Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H7BZA7H7BZA7_HUMAN
SUN domain-containing protein 3
SUN3
281Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H7C2N0H7C2N0_HUMAN
SUN domain-containing protein 3
SUN3
170Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A0A0MSG9A0A0A0MSG9_HUMAN
SUN domain-containing protein 3
SUN3
266Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAP97300 differs from that shown. Reason: Frameshift.Curated
The sequence EAL23808 differs from that shown. Reason: Erroneous gene model prediction.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti231 – 232Missing in AAP97300 (Ref. 1) Curated2
Sequence conflicti292K → R in BAG63413 (PubMed:14702039).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_037458127I → V1 PublicationCorresponds to variant dbSNP:rs17852360Ensembl.1
Natural variantiVAR_037459177L → V. Corresponds to variant dbSNP:rs7797657Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0297481 – 100Missing in isoform 2. 1 PublicationAdd BLAST100
Alternative sequenceiVSP_0556242 – 61SGKTK…TFLLV → EDYSKYNAYTDFSSCRLECS GAILAHCNLHLLGSSISPAS ASRVAGTT in isoform 3. 1 PublicationAdd BLAST60
Alternative sequenceiVSP_029749287Y → YVQRYMCRFVIQA in isoform 2. 1 Publication1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AF429967 mRNA Translation: AAP97300.1 Frameshift.
AK302011 mRNA Translation: BAG63413.1
DQ099386 mRNA Translation: AAZ13762.1
AC069279 Genomic DNA No translation available.
CH236958 Genomic DNA Translation: EAL23808.1 Sequence problems.
CH471128 Genomic DNA Translation: EAW60999.1
CH471128 Genomic DNA Translation: EAW61000.1
BC026189 mRNA Translation: AAH26189.3

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS34636.1 [Q8TAQ9-1]
CCDS64647.1 [Q8TAQ9-3]

NCBI Reference Sequences

More...
RefSeqi
NP_001025190.1, NM_001030019.1 [Q8TAQ9-1]
NP_001271279.1, NM_001284350.1 [Q8TAQ9-3]
NP_689995.3, NM_152782.3 [Q8TAQ9-1]
XP_016867419.1, XM_017011930.1 [Q8TAQ9-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000297325; ENSP00000297325; ENSG00000164744 [Q8TAQ9-1]
ENST00000395572; ENSP00000378939; ENSG00000164744 [Q8TAQ9-1]
ENST00000412142; ENSP00000410204; ENSG00000164744 [Q8TAQ9-3]
ENST00000438771; ENSP00000409077; ENSG00000164744 [Q8TAQ9-2]

Database of genes from NCBI RefSeq genomes

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GeneIDi
256979

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:256979

UCSC genome browser

More...
UCSCi
uc003tof.4 human [Q8TAQ9-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF429967 mRNA Translation: AAP97300.1 Frameshift.
AK302011 mRNA Translation: BAG63413.1
DQ099386 mRNA Translation: AAZ13762.1
AC069279 Genomic DNA No translation available.
CH236958 Genomic DNA Translation: EAL23808.1 Sequence problems.
CH471128 Genomic DNA Translation: EAW60999.1
CH471128 Genomic DNA Translation: EAW61000.1
BC026189 mRNA Translation: AAH26189.3
CCDSiCCDS34636.1 [Q8TAQ9-1]
CCDS64647.1 [Q8TAQ9-3]
RefSeqiNP_001025190.1, NM_001030019.1 [Q8TAQ9-1]
NP_001271279.1, NM_001284350.1 [Q8TAQ9-3]
NP_689995.3, NM_152782.3 [Q8TAQ9-1]
XP_016867419.1, XM_017011930.1 [Q8TAQ9-1]

3D structure databases

SMRiQ8TAQ9
ModBaseiSearch...

Protein-protein interaction databases

BioGridi129187, 1 interactor
STRINGi9606.ENSP00000297325

PTM databases

iPTMnetiQ8TAQ9
PhosphoSitePlusiQ8TAQ9

Polymorphism and mutation databases

BioMutaiSUN3
DMDMi162416243

Proteomic databases

MassIVEiQ8TAQ9
PaxDbiQ8TAQ9
PeptideAtlasiQ8TAQ9
PRIDEiQ8TAQ9
ProteomicsDBi18821
73909 [Q8TAQ9-1]
73910 [Q8TAQ9-2]

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
1892 44 antibodies

Genome annotation databases

EnsembliENST00000297325; ENSP00000297325; ENSG00000164744 [Q8TAQ9-1]
ENST00000395572; ENSP00000378939; ENSG00000164744 [Q8TAQ9-1]
ENST00000412142; ENSP00000410204; ENSG00000164744 [Q8TAQ9-3]
ENST00000438771; ENSP00000409077; ENSG00000164744 [Q8TAQ9-2]
GeneIDi256979
KEGGihsa:256979
UCSCiuc003tof.4 human [Q8TAQ9-1]

Organism-specific databases

Comparative Toxicogenomics Database

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CTDi
256979
DisGeNETi256979

GeneCards: human genes, protein and diseases

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GeneCardsi
SUN3
HGNCiHGNC:22429 SUN3
HPAiENSG00000164744 Tissue enriched (testis)
neXtProtiNX_Q8TAQ9
OpenTargetsiENSG00000164744
PharmGKBiPA165618375

GenAtlas: human gene database

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GenAtlasi
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Phylogenomic databases

eggNOGiKOG2687 Eukaryota
ENOG410YM6S LUCA
GeneTreeiENSGT00940000161393
HOGENOMiCLU_043737_0_0_1
InParanoidiQ8TAQ9
KOiK21874
OMAiHPNYTCL
OrthoDBi1569602at2759
PhylomeDBiQ8TAQ9
TreeFamiTF323915

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

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ChiTaRSi
SUN3 human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

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GenomeRNAii
256979
PharosiQ8TAQ9 Tdark

Protein Ontology

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PROi
PR:Q8TAQ9
RNActiQ8TAQ9 protein

Gene expression databases

BgeeiENSG00000164744 Expressed in right testis and 66 other tissues
ExpressionAtlasiQ8TAQ9 baseline and differential
GenevisibleiQ8TAQ9 HS

Family and domain databases

Gene3Di2.60.120.260, 1 hit
InterProiView protein in InterPro
IPR008979 Galactose-bd-like_sf
IPR030274 SUN3
IPR012919 SUN_dom
PANTHERiPTHR12911:SF24 PTHR12911:SF24, 1 hit
PfamiView protein in Pfam
PF07738 Sad1_UNC, 1 hit
PROSITEiView protein in PROSITE
PS51469 SUN, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiSUN3_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q8TAQ9
Secondary accession number(s): A4D2F3
, B4DXK1, D3DVM3, E7EWC8, Q4F965, Q7Z4U8
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 4, 2007
Last sequence update: December 4, 2007
Last modified: April 22, 2020
This is version 139 of the entry and version 4 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human chromosome 7
    Human chromosome 7: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
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