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Protein

Uncharacterized protein C9orf43

Gene

C9orf43

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized protein C9orf43
Gene namesi
Name:C9orf43
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 9

Organism-specific databases

EuPathDBiHostDB:ENSG00000157653.11
HGNCiHGNC:23570 C9orf43
neXtProtiNX_Q8TAL5

Pathology & Biotechi

Organism-specific databases

DisGeNETi257169
OpenTargetsiENSG00000157653
PharmGKBiPA134972642

Polymorphism and mutation databases

BioMutaiC9orf43
DMDMi71152406

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000896921 – 461Uncharacterized protein C9orf43Add BLAST461

Proteomic databases

EPDiQ8TAL5
PaxDbiQ8TAL5
PeptideAtlasiQ8TAL5
PRIDEiQ8TAL5
ProteomicsDBi73890

PTM databases

iPTMnetiQ8TAL5
PhosphoSitePlusiQ8TAL5

Expressioni

Gene expression databases

BgeeiENSG00000157653 Expressed in 81 organ(s), highest expression level in testis
CleanExiHS_C9orf43
ExpressionAtlasiQ8TAL5 baseline and differential
GenevisibleiQ8TAL5 HS

Organism-specific databases

HPAiHPA021310

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
RABGAP1LQ5R372-23EBI-10694291,EBI-10692254

Protein-protein interaction databases

BioGridi129203, 5 interactors
IntActiQ8TAL5, 1 interactor
STRINGi9606.ENSP00000288462

Structurei

3D structure databases

ProteinModelPortaliQ8TAL5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi293 – 304Gln-richAdd BLAST12

Phylogenomic databases

eggNOGiENOG410IKP4 Eukaryota
ENOG41115SE LUCA
GeneTreeiENSGT00390000013600
HOGENOMiHOG000111639
HOVERGENiHBG061078
InParanoidiQ8TAL5
OMAiVCQHPQC
OrthoDBiEOG091G0F2U
PhylomeDBiQ8TAL5
TreeFamiTF337505

Family and domain databases

InterProiView protein in InterPro
IPR029134 DUF4647
PANTHERiPTHR36130 PTHR36130, 1 hit
PfamiView protein in Pfam
PF15504 DUF4647, 1 hit
ProDomiView protein in ProDom or Entries sharing at least one domain
PD575093 PD575093, 1 hit

Sequencei

Sequence statusi: Complete.

Q8TAL5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MDLPDESQWD ETTCGLAVCQ HPQCWATIRR IERGHPRILG SSCKTPLDAE
60 70 80 90 100
DKLPVLTVVD ILDSGFAAHH LPECTFTKAH SLLSQSSKFY SKFHGRPPKG
110 120 130 140 150
LPDKSLINCT NRLPKFPVLN LNETQLPCPE DVRNMVVLWI PEETEIHVSQ
160 170 180 190 200
HGKKKRKNSA VKSKSFLGLS GNQSAGTRVG TPGMIVPPPT PVQLSEQFSS
210 220 230 240 250
DFLPLWAQSE ALPQDLLKEL LPGGKQTMLC PEMKIKLAMM KKNLPLEKNR
260 270 280 290 300
PDSVISSKMF LSIHRLTLER PALRYPERLK KLHNLKTEGY RKQQQRQQQQ
310 320 330 340 350
QQQQKKVKTP IKKQEAKKKA KSDPGIQSTS HKHPVTTVHD RLYGYRTLPG
360 370 380 390 400
QNSDMKQQQQ MEKGTTSKQD STERPKMNYY DHADFHHSVK SPELYETEPT
410 420 430 440 450
NKDISAPVDA VPEAQAARQK KISFNFSEIM ASTGWNSELK LLRILQDTDD
460
EDEEDQSSGA E
Length:461
Mass (Da):52,222
Last modified:June 1, 2002 - v1
Checksum:i5091BF1A9AFAD68E
GO

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Natural variantiVAR_061597252D → G. Corresponds to variant dbSNP:rs41313331Ensembl.1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL137066 Genomic DNA No translation available.
BC026884 mRNA Translation: AAH26884.1
BC033037 mRNA Translation: AAH33037.1
CCDSiCCDS6796.1
RefSeqiNP_001265558.1, NM_001278629.1
NP_689999.1, NM_152786.2
UniGeneiHs.632691

Genome annotation databases

EnsembliENST00000288462; ENSP00000288462; ENSG00000157653
ENST00000374165; ENSP00000363280; ENSG00000157653
GeneIDi257169
KEGGihsa:257169
UCSCiuc004bho.6 human

Keywords - Coding sequence diversityi

Polymorphism

Similar proteinsi

Entry informationi

Entry nameiCI043_HUMAN
AccessioniPrimary (citable) accession number: Q8TAL5
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 19, 2005
Last sequence update: June 1, 2002
Last modified: September 12, 2018
This is version 111 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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