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Entry version 126 (12 Aug 2020)
Sequence version 1 (01 Jun 2002)
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Protein

UPF0500 protein C1orf216

Gene

C1orf216

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...
PathwayCommonsi
Q8TAB5

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
UPF0500 protein C1orf216
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 1

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000142686.7

Human Gene Nomenclature Database

More...
HGNCi
HGNC:26800, C1orf216

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q8TAB5

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

More...
OpenTargetsi
ENSG00000142686

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA162378892

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q8TAB5, Tdark

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
C1orf216

Domain mapping of disease mutations (DMDM)

More...
DMDMi
74730336

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003091781 – 229UPF0500 protein C1orf216Add BLAST229

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q8TAB5

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q8TAB5

PeptideAtlas

More...
PeptideAtlasi
Q8TAB5

PRoteomics IDEntifications database

More...
PRIDEi
Q8TAB5

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
73852

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q8TAB5

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q8TAB5

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000142686, Expressed in occipital lobe and 206 other tissues

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q8TAB5, HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
ENSG00000142686, Tissue enhanced (brain)

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Q8TAB5
With#Exp.IntAct
ABI2 - isoform 2 [Q9NYB9-2]3EBI-747505,EBI-11096309
AIMP2 [Q13155]3EBI-747505,EBI-745226
AMOT [A2BDD9]3EBI-747505,EBI-17286414
AMOT - isoform 2 [Q4VCS5-2]3EBI-747505,EBI-3891843
BORCS6 [Q96GS4]3EBI-747505,EBI-10193358
CCDC114 [Q96M63]6EBI-747505,EBI-10173858
CCDC136 - isoform 2 [Q96JN2-2]3EBI-747505,EBI-10171416
CCDC197 [Q8NCU1]8EBI-747505,EBI-750686
CDR2 [Q01850]6EBI-747505,EBI-1181367
CDR2L [Q86X02]3EBI-747505,EBI-11063830
CENPH [Q9H3R5]3EBI-747505,EBI-1003700
CEP55 [Q53EZ4]3EBI-747505,EBI-747776
CMC2 [Q9NRP2]3EBI-747505,EBI-16780661
DES [P17661]3EBI-747505,EBI-1055572
DMAP1 [Q9NPF5]5EBI-747505,EBI-399105
EIF3F [O00303]3EBI-747505,EBI-711990
EXOC5 [O00471]3EBI-747505,EBI-949824
FSD2 [A1L4K1]3EBI-747505,EBI-5661036
GGA1 [Q9UJY5]3EBI-747505,EBI-447141
GGA1 - isoform 4 [Q9UJY5-4]3EBI-747505,EBI-12108696
HAP1 [P54257]3EBI-747505,EBI-712814
HAUS8 [Q9BT25]3EBI-747505,EBI-2558143
IFT20 - isoform 3 [Q8IY31-3]3EBI-747505,EBI-9091197
KLHL20 [Q9BS75]3EBI-747505,EBI-10693436
KRT13 [A1A4E9]3EBI-747505,EBI-10171552
KRT15 [P19012]4EBI-747505,EBI-739566
KRT16 [P08779]3EBI-747505,EBI-356410
KRT24 [Q2M2I5]5EBI-747505,EBI-2952736
KRT27 [Q7Z3Y8]3EBI-747505,EBI-3044087
KRT31 [Q15323]6EBI-747505,EBI-948001
KRT33B [Q14525]3EBI-747505,EBI-1049638
KRT34 [O76011]3EBI-747505,EBI-1047093
KRT36 - isoform 2 [O76013-2]3EBI-747505,EBI-11958506
KRT38 [O76015]6EBI-747505,EBI-1047263
KRT39 [Q6A163]3EBI-747505,EBI-11958242
KRT40 [Q6A162]3EBI-747505,EBI-10171697
KRT75 [O95678]3EBI-747505,EBI-2949715
KRT76 [Q01546]3EBI-747505,EBI-2952745
LRRC61 [Q9BV99]3EBI-747505,EBI-2350424
MAGEA6 [P43360]3EBI-747505,EBI-1045155
MDFI [Q99750]3EBI-747505,EBI-724076
MED4 [Q9NPJ6]3EBI-747505,EBI-394607
MIS18A [Q9NYP9]3EBI-747505,EBI-1104552
MLPH [Q9BV36]3EBI-747505,EBI-7042162
MRFAP1L1 [Q96HT8]3EBI-747505,EBI-748896
MTUS2 [Q5JR59]4EBI-747505,EBI-742948
MTUS2 - isoform 2 [Q5JR59-3]3EBI-747505,EBI-11522433
MYRIP [Q8NFW9]6EBI-747505,EBI-1759414
NECAB2 - isoform 2 [Q7Z6G3-2]3EBI-747505,EBI-10172876
NMI [Q13287]6EBI-747505,EBI-372942
NRBF2 [Q96F24]3EBI-747505,EBI-2362014
NUP62 [P37198]6EBI-747505,EBI-347978
PKNOX2 [Q96KN3]5EBI-747505,EBI-2692890
PPP1R16A [Q96I34]3EBI-747505,EBI-710402
PSMC6 [P62333]4EBI-747505,EBI-357669
RALBP1 [Q15311]6EBI-747505,EBI-749285
SERTAD3 [Q9UJW9]3EBI-747505,EBI-748621
SNW1 [Q13573]3EBI-747505,EBI-632715
THAP1 [Q9NVV9]3EBI-747505,EBI-741515
TLE5 [Q08117]3EBI-747505,EBI-717810
TMCO5A [Q8N6Q1]3EBI-747505,EBI-12821895
TPM1 [P09493]3EBI-747505,EBI-351158
TPM3 [P06753]4EBI-747505,EBI-355607
TPM3 [Q5VU62]3EBI-747505,EBI-10184033
TRAF1 [Q13077]6EBI-747505,EBI-359224
TRIM54 [Q9BYV2]3EBI-747505,EBI-2130429
TRIM72 [Q6ZMU5]3EBI-747505,EBI-2341648
USHBP1 [Q8N6Y0]7EBI-747505,EBI-739895
VPS52 [Q8N1B4]3EBI-747505,EBI-2799833
ZNF620 [Q6ZNG0]3EBI-747505,EBI-4395669

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
126079, 28 interactors

Protein interaction database and analysis system

More...
IntActi
Q8TAB5, 75 interactors

Molecular INTeraction database

More...
MINTi
Q8TAB5

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000425166

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q8TAB5, protein

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the UPF0500 family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG502S1PX, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000001867

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_1156086_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q8TAB5

Identification of Orthologs from Complete Genome Data

More...
OMAi
WHGMPGQ

Database of Orthologous Groups

More...
OrthoDBi
1593675at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q8TAB5

TreeFam database of animal gene trees

More...
TreeFami
TF335932

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR027812, DUF4653

The PANTHER Classification System

More...
PANTHERi
PTHR35673, PTHR35673, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF15546, DUF4653, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q8TAB5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MFAIQPGLAE GGQFLGDPPP GLCQPELQPD SNSNFMASAK DANENWHGMP
60 70 80 90 100
GRVEPILRRS SSESPSDNQA FQAPGSPEEG VRSPPEGAEI PGAEPEKMGG
110 120 130 140 150
AGTVCSPLED NGYASSSLSI DSRSSSPEPA CGTPRGPGPP DPLLPSVAQA
160 170 180 190 200
VQHLQVQERY KEQEKEKHHV HLVMYRRLAL LQWIRGLQHQ LIDQQARLQE
210 220
SFDTILDNRK ELIRCLQQRA APSRPQDQA
Length:229
Mass (Da):24,968
Last modified:June 1, 2002 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i281250E30DC4E730
GO

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence BAC04799 differs from that shown. Reason: Erroneous initiation.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti19P → T in BAC04799 (PubMed:14702039).Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AK096303 mRNA Translation: BAC04755.1
AK096466 mRNA Translation: BAC04799.1 Different initiation.
CH471059 Genomic DNA Translation: EAX07403.1
CH471059 Genomic DNA Translation: EAX07404.1
BC026909 mRNA Translation: AAH26909.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS395.1

NCBI Reference Sequences

More...
RefSeqi
NP_001335620.1, NM_001348691.1
NP_689587.1, NM_152374.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000270815; ENSP00000425166; ENSG00000142686

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
127703

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:127703

UCSC genome browser

More...
UCSCi
uc001bzh.2, human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK096303 mRNA Translation: BAC04755.1
AK096466 mRNA Translation: BAC04799.1 Different initiation.
CH471059 Genomic DNA Translation: EAX07403.1
CH471059 Genomic DNA Translation: EAX07404.1
BC026909 mRNA Translation: AAH26909.1
CCDSiCCDS395.1
RefSeqiNP_001335620.1, NM_001348691.1
NP_689587.1, NM_152374.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

BioGRIDi126079, 28 interactors
IntActiQ8TAB5, 75 interactors
MINTiQ8TAB5
STRINGi9606.ENSP00000425166

PTM databases

iPTMnetiQ8TAB5
PhosphoSitePlusiQ8TAB5

Polymorphism and mutation databases

BioMutaiC1orf216
DMDMi74730336

Proteomic databases

jPOSTiQ8TAB5
PaxDbiQ8TAB5
PeptideAtlasiQ8TAB5
PRIDEiQ8TAB5
ProteomicsDBi73852

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
31583, 84 antibodies

The DNASU plasmid repository

More...
DNASUi
127703

Genome annotation databases

EnsembliENST00000270815; ENSP00000425166; ENSG00000142686
GeneIDi127703
KEGGihsa:127703
UCSCiuc001bzh.2, human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
127703
EuPathDBiHostDB:ENSG00000142686.7

GeneCards: human genes, protein and diseases

More...
GeneCardsi
C1orf216
HGNCiHGNC:26800, C1orf216
HPAiENSG00000142686, Tissue enhanced (brain)
neXtProtiNX_Q8TAB5
OpenTargetsiENSG00000142686
PharmGKBiPA162378892

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiENOG502S1PX, Eukaryota
GeneTreeiENSGT00390000001867
HOGENOMiCLU_1156086_0_0_1
InParanoidiQ8TAB5
OMAiWHGMPGQ
OrthoDBi1593675at2759
PhylomeDBiQ8TAB5
TreeFamiTF335932

Enzyme and pathway databases

PathwayCommonsiQ8TAB5

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
127703, 32 hits in 863 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
C1orf216, human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
127703
PharosiQ8TAB5, Tdark

Protein Ontology

More...
PROi
PR:Q8TAB5
RNActiQ8TAB5, protein

Gene expression databases

BgeeiENSG00000142686, Expressed in occipital lobe and 206 other tissues
GenevisibleiQ8TAB5, HS

Family and domain databases

InterProiView protein in InterPro
IPR027812, DUF4653
PANTHERiPTHR35673, PTHR35673, 1 hit
PfamiView protein in Pfam
PF15546, DUF4653, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiCA216_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q8TAB5
Secondary accession number(s): D3DPS1, Q8N8N6
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 13, 2007
Last sequence update: June 1, 2002
Last modified: August 12, 2020
This is version 126 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Technical termi

Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Uncharacterized protein families (UPF)
    List of uncharacterized protein family (UPF) entries
  3. Human chromosome 1
    Human chromosome 1: entries, gene names and cross-references to MIM
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