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Protein

Metallothionein-1

Gene
N/A
Organism
Tetrahymena thermophila
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

The metallothioneins are involved in the cellular sequestration of toxic metal ions. Binds 12 cadmium ions per molecule (By similarity).By similarity

GO - Molecular functioni

Keywordsi

LigandCadmium, Metal-binding, Metal-thiolate cluster

Names & Taxonomyi

Protein namesi
Recommended name:
Metallothionein-1
Short name:
MT-1
OrganismiTetrahymena thermophila
Taxonomic identifieri5911 [NCBI]
Taxonomic lineageiEukaryotaAlveolataCiliophoraIntramacronucleataOligohymenophoreaHymenostomatidaTetrahymeninaTetrahymenidaeTetrahymena

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001973601 – 107Metallothionein-1Add BLAST107

Structurei

3D structure databases

ProteinModelPortaliQ8T6B3
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Family and domain databases

InterProiView protein in InterPro
IPR012484 Metalthion_7
PfamiView protein in Pfam
PF07846 Metallothio_Cad, 2 hits

Sequencei

Sequence statusi: Complete.

Q8T6B3-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MDKVNNNCCC GENAKPCCTD PNSGCCCVSE TNNCCKSDKK ECCTGTGEGC
60 70 80 90 100
KWTGCKCCQP AKSGCCCGDK AKACCTDPNS GCCCSSKTNK CCDSTNKTEC

KTCECCK
Length:107
Mass (Da):11,179
Last modified:June 1, 2002 - v1
Checksum:i05C848DF1A8E4647
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF479587 Genomic DNA Translation: AAL87688.1

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF479587 Genomic DNA Translation: AAL87688.1

3D structure databases

ProteinModelPortaliQ8T6B3
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

InterProiView protein in InterPro
IPR012484 Metalthion_7
PfamiView protein in Pfam
PF07846 Metallothio_Cad, 2 hits
ProtoNetiSearch...

Entry informationi

Entry nameiMT1_TETTH
AccessioniPrimary (citable) accession number: Q8T6B3
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 25, 2002
Last sequence update: June 1, 2002
Last modified: November 11, 2015
This is version 34 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Metallothioneins
    Classification of metallothioneins and list of entries
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Main funding by: National Institutes of Health

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