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Protein

40S ribosomal protein S23

Gene

RpS23

Organism
Drosophila melanogaster (Fruit fly)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionRibonucleoprotein, Ribosomal protein

Enzyme and pathway databases

ReactomeiR-DME-156827 L13a-mediated translational silencing of Ceruloplasmin expression
R-DME-1799339 SRP-dependent cotranslational protein targeting to membrane
R-DME-6791226 Major pathway of rRNA processing in the nucleolus and cytosol
R-DME-72649 Translation initiation complex formation
R-DME-72689 Formation of a pool of free 40S subunits
R-DME-72695 Formation of the ternary complex, and subsequently, the 43S complex
R-DME-72702 Ribosomal scanning and start codon recognition
R-DME-72706 GTP hydrolysis and joining of the 60S ribosomal subunit
R-DME-975956 Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
R-DME-975957 Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)

Names & Taxonomyi

Protein namesi
Recommended name:
40S ribosomal protein S23
Gene namesi
Name:RpS23
ORF Names:CG8415
OrganismiDrosophila melanogaster (Fruit fly)
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
Proteomesi
  • UP000000803 Componenti: Chromosome 2R

Organism-specific databases

FlyBaseiFBgn0033912 RpS23

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Endoplasmic reticulum

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001464651 – 14340S ribosomal protein S23Add BLAST143

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei623-hydroxyproline1 Publication1

Post-translational modificationi

Hydroxylation at Pro-62 affects translation termination efficiency.1 Publication

Keywords - PTMi

Hydroxylation

Proteomic databases

PaxDbiQ8T3U2
PRIDEiQ8T3U2

Expressioni

Gene expression databases

BgeeiFBgn0033912
ExpressionAtlasiQ8T3U2 baseline and differential
GenevisibleiQ8T3U2 DM

Interactioni

Subunit structurei

Component of the 40S small ribosomal subunit.1 Publication

Protein-protein interaction databases

BioGridi62326, 26 interactors
IntActiQ8T3U2, 20 interactors
MINTiQ8T3U2
STRINGi7227.FBpp0086701

Structurei

3D structure databases

ProteinModelPortaliQ8T3U2
SMRiQ8T3U2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiKOG1749 Eukaryota
COG0048 LUCA
GeneTreeiENSGT00550000074784
InParanoidiQ8T3U2
KOiK02973
OMAiKFRWSQR
OrthoDBiEOG091G0R2G
PhylomeDBiQ8T3U2

Family and domain databases

CDDicd03367 Ribosomal_S23, 1 hit
InterProiView protein in InterPro
IPR012340 NA-bd_OB-fold
IPR006032 Ribosomal_S12/S23
IPR005680 Ribosomal_S23_euk/arc
PANTHERiPTHR11652 PTHR11652, 1 hit
PfamiView protein in Pfam
PF00164 Ribosom_S12_S23, 1 hit
PIRSFiPIRSF002133 Ribosomal_S12/S23, 1 hit
SUPFAMiSSF50249 SSF50249, 1 hit
TIGRFAMsiTIGR00982 uS12_E_A, 1 hit
PROSITEiView protein in PROSITE
PS00055 RIBOSOMAL_S12, 1 hit

Sequencei

Sequence statusi: Complete.

Q8T3U2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGKPRGLRTA RKHVNHRRDQ RWADKDYKKA HLGTRWKANP FGGASHAKGI
60 70 80 90 100
VLEKVGVEAK QPNSAIRKCV RVQLIKNGKK ITAFVPRDGS LNYIEENDEV
110 120 130 140
LVAGFGRKGH AVGDIPGVRF KVVKVANVSL LALYKEKKER PRS
Length:143
Mass (Da):16,017
Last modified:June 1, 2002 - v1
Checksum:iB1B700EC902F2C47
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE013599 Genomic DNA Translation: AAF58277.2
AY089523 mRNA Translation: AAL90261.1
RefSeqiNP_001286410.1, NM_001299481.1
NP_610939.2, NM_137095.3
UniGeneiDm.4964

Genome annotation databases

EnsemblMetazoaiFBtr0087575; FBpp0086701; FBgn0033912
FBtr0339970; FBpp0308991; FBgn0033912
GeneIDi36576
KEGGidme:Dmel_CG8415

Similar proteinsi

Entry informationi

Entry nameiRS23_DROME
AccessioniPrimary (citable) accession number: Q8T3U2
Secondary accession number(s): Q9V6Z0
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 5, 2004
Last sequence update: June 1, 2002
Last modified: July 18, 2018
This is version 124 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programDrosophila annotation project

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. Drosophila
    Drosophila: entries, gene names and cross-references to FlyBase
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. Ribosomal proteins
    Ribosomal proteins families and list of entries
  4. SIMILARITY comments
    Index of protein domains and families

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