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Protein
Submitted name:

Phosphatidylinositol 4-kinase alpha type II

Gene

Pi4KIIalpha

Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  • 1-phosphatidylinositol 4-kinase activity Source: FlyBase

GO - Biological processi

Keywordsi

Molecular functionKinaseImported, Transferase

Enzyme and pathway databases

ReactomeiR-DME-1483248 Synthesis of PIPs at the ER membrane
R-DME-1660499 Synthesis of PIPs at the plasma membrane
R-DME-1660514 Synthesis of PIPs at the Golgi membrane
R-DME-1660516 Synthesis of PIPs at the early endosome membrane

Names & Taxonomyi

Protein namesi
Submitted name:
Phosphatidylinositol 4-kinase alpha type IIImported
Submitted name:
Phosphatidylinositol 4-kinase type II alphaImported
Gene namesi
Name:Pi4KIIalphaImported
Synonyms:PI4KII alphaImported, Pi4KII-alphaImported
ORF Names:CG2929Imported
OrganismiDrosophila melanogaster (Fruit fly)Imported
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora

Organism-specific databases

FlyBaseiFBgn0037339 Pi4KIIalpha

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Proteomic databases

PeptideAtlasiQ8STF7
PRIDEiQ8STF7

Expressioni

Gene expression databases

BgeeiFBgn0037339 Expressed in 29 organ(s), highest expression level in cleaving embryo
ExpressionAtlasiQ8STF7 baseline and differential

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini292 – 663PI3K/PI4KInterPro annotationAdd BLAST372

Phylogenomic databases

eggNOGiKOG2381 Eukaryota
ENOG410XP06 LUCA
OrthoDBiEOG091G09F3

Family and domain databases

InterProiView protein in InterPro
IPR000403 PI3/4_kinase_cat_dom
PfamiView protein in Pfam
PF00454 PI3_PI4_kinase, 1 hit

Sequencei

Sequence statusi: Complete.

Q8STF7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSGARDQTDP PLLQLEDEVD LIGDFAKDQP PPRNQLSPLL NGFESTSNQL
60 70 80 90 100
TTKVEINTVG MGKRKTRRRG KKAREPMLLS VDDEDDEEEA QEERNHTNGL
110 120 130 140 150
PPGEESAGGD AVIQKPQLDN LVMHYDDQID DEDGEEAVLL KRSSNPRNQR
160 170 180 190 200
LKGSAEDSID SSSQQPPIIC HIAPAKVASS ALTSPLKTTS HTALARHPHD
210 220 230 240 250
EADDICLVPE IDFEGMSTDA GSDNRESQPL LGGGNASHGS RISELLGGLG
260 270 280 290 300
RGHDHVEFVS NTFGDDPLFS EIVAKAEGAI ENGVLPERIY QGSSGSYFVK
310 320 330 340 350
DASHQCLAVF KPKDEEPYGR LNPKWTKWMH KLCCPCCFGR ACLIPNQGYL
360 370 380 390 400
SESGASLVDQ KLNLNVVPKT RVVRLVAESF NYARIDRQKA KLKKRIKEHY
410 420 430 440 450
PSAHFNRMSL PLKTGSFQLF VEGYKDADYW LRRFESEPLP PSVAKSFQLQ
460 470 480 490 500
FERLVVLDYI IRNTDRGNDN WLIKYVAPKI TTQVGGTGGR TMHGVVTPKL
510 520 530 540 550
PNALGASKIV DLNEPPQASP KPTTGGRPSN HLAGGAATSA QQDSSSLASS
560 570 580 590 600
EDEPSSRSPP TSEPDWNVVN SAFIRIAAID NGLAFPFKHP DSWRAYPYHW
610 620 630 640 650
AWLPQAKIPF SEEIKEQVLP QLSDMNFVEE ICTELLYLFQ QDRGFDKRLF
660 670 680 690 700
ERQMSVMRGQ ILNLTQALRD GKSPVQLVQM PAVIVERSSG SRFFSFTQRF
710
QNKSPFFSWW
Length:710
Mass (Da):79,010
Last modified:June 1, 2002 - v1
Checksum:i42CD737B491D876E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF498318 mRNA Translation: AAM18079.1
AJ440722 mRNA Translation: CAD29429.1

Similar proteinsi

Entry informationi

Entry nameiQ8STF7_DROME
AccessioniPrimary (citable) accession number: Q8STF7
Entry historyiIntegrated into UniProtKB/TrEMBL: June 1, 2002
Last sequence update: June 1, 2002
Last modified: September 12, 2018
This is version 81 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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