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Entry version 107 (16 Oct 2019)
Sequence version 2 (01 Jun 2003)
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Protein

Bifunctional serine/threonine-protein kinase/NEDD4-like E3 ubiquitin-protein ligase

Gene

DDB_G0276527

Organism
Dictyostelium discoideum (Slime mold)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

  • S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine. EC:2.3.2.26

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section describes the metabolic pathway(s) associated with a protein.<p><a href='/help/pathway' target='_top'>More...</a></p>Pathwayi: protein ubiquitination

This protein is involved in the pathway protein ubiquitination, which is part of Protein modification.
View all proteins of this organism that are known to be involved in the pathway protein ubiquitination and in Protein modification.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes the interaction between a single amino acid and another chemical entity. Priority is given to the annotation of physiological ligands.<p><a href='/help/binding' target='_top'>More...</a></p>Binding sitei1184ATPPROSITE-ProRule annotation1
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section is used for enzymes and indicates the residues directly involved in catalysis.<p><a href='/help/act_site' target='_top'>More...</a></p>Active sitei1281Proton acceptorPROSITE-ProRule annotation1
Active sitei1855Glycyl thioester intermediatePROSITE-ProRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes a region in the protein which binds nucleotide phosphates. It always involves more than one amino acid and includes all residues involved in nucleotide-binding.<p><a href='/help/np_bind' target='_top'>More...</a></p>Nucleotide bindingi1164 – 1172ATPPROSITE-ProRule annotation9

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionKinase, Serine/threonine-protein kinase, Transferase
Biological processUbl conjugation pathway
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-DDI-983168 Antigen processing: Ubiquitination & Proteasome degradation

UniPathway: a resource for the exploration and annotation of metabolic pathways

More...
UniPathwayi
UPA00143

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Bifunctional serine/threonine-protein kinase/NEDD4-like E3 ubiquitin-protein ligase
Including the following 2 domains:
Probable serine/threonine-protein kinase DDB_G0276527 (EC:2.7.11.1)
Probable NEDD4-like E3 ubiquitin-protein ligase DDB_G0276527 (EC:2.3.2.26)
Alternative name(s):
HECT-type E3 ubiquitin transferase DDB_G0276527
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
ORF Names:DDB_G0276527
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiDictyostelium discoideum (Slime mold)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri44689 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaAmoebozoaEvoseaEumycetozoaDictyostelidsDictyostelialesDictyosteliaceaeDictyostelium
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002195 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componentsi: Chromosome 2, Unassembled WGS sequence

Organism-specific databases

Dictyostelium discoideum online informatics resource

More...
dictyBasei
DDB_G0276527

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003682271 – 1887Bifunctional serine/threonine-protein kinase/NEDD4-like E3 ubiquitin-protein ligaseAdd BLAST1887

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q8SSY6

PRoteomics IDEntifications database

More...
PRIDEi
Q8SSY6

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
44689.DDB0219986

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q8SSY6

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati206 – 260RCC1 1Add BLAST55
Repeati262 – 314RCC1 2Add BLAST53
Repeati356 – 409RCC1 3Add BLAST54
Repeati411 – 470RCC1 4Add BLAST60
Repeati472 – 528RCC1 5Add BLAST57
Repeati529 – 581RCC1 6Add BLAST53
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini1158 – 1437Protein kinasePROSITE-ProRule annotationAdd BLAST280
Domaini1501 – 1887HECTPROSITE-ProRule annotationAdd BLAST387

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi74 – 94Poly-AsnAdd BLAST21
Compositional biasi131 – 136Poly-Glu6
Compositional biasi281 – 284Poly-Ser4
Compositional biasi299 – 308Poly-Asn10
Compositional biasi311 – 318Poly-Asn8
Compositional biasi446 – 451Poly-Gln6
Compositional biasi644 – 647Poly-Thr4
Compositional biasi791 – 797Poly-Thr7
Compositional biasi800 – 816Poly-ThrAdd BLAST17
Compositional biasi847 – 850Poly-Glu4
Compositional biasi904 – 914Poly-ThrAdd BLAST11
Compositional biasi1029 – 1032Poly-Asp4
Compositional biasi1041 – 1067Poly-AsnAdd BLAST27
Compositional biasi1082 – 1089Poly-Asn8
Compositional biasi1242 – 1250Poly-Asn9
Compositional biasi1358 – 1365Poly-Asn8
Compositional biasi1374 – 1383Poly-Asn10
Compositional biasi1585 – 1591Poly-Asn7
Compositional biasi1594 – 1626Poly-AsnAdd BLAST33

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

In the N-terminal section; belongs to the protein kinase superfamily. Ser/Thr protein kinase family.Curated
In the C-terminal section; belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.Curated

Keywords - Domaini

Repeat

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410INH6 Eukaryota
KOG0586 Eukaryota
KOG0941 Eukaryota
COG5021 LUCA
COG5184 LUCA
ENOG410XNQ0 LUCA

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q8SSY6

Identification of Orthologs from Complete Genome Data

More...
OMAi
NAHFALF

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.130.10.30, 2 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR000569 HECT_dom
IPR035983 Hect_E3_ubiquitin_ligase
IPR011009 Kinase-like_dom_sf
IPR000719 Prot_kinase_dom
IPR009091 RCC1/BLIP-II
IPR000408 Reg_chr_condens
IPR008271 Ser/Thr_kinase_AS

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00632 HECT, 1 hit
PF00069 Pkinase, 1 hit
PF00415 RCC1, 6 hits

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR00633 RCCNDNSATION

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00119 HECTc, 1 hit
SM00220 S_TKc, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF50985 SSF50985, 1 hit
SSF56112 SSF56112, 1 hit
SSF56204 SSF56204, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50237 HECT, 1 hit
PS50011 PROTEIN_KINASE_DOM, 1 hit
PS00108 PROTEIN_KINASE_ST, 1 hit
PS00626 RCC1_2, 2 hits
PS50012 RCC1_3, 6 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q8SSY6-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSLFFKSIKS KIEETLNHTP QVNLFNNSNN GGNNSNNGGN NSTPTLTKTP
60 70 80 90 100
STTNFPYNDY KNYTYKYVYD NTDNYNFNNN NNNNNNNNNN NNNNTKENNF
110 120 130 140 150
KSIRESASIY KNNEEINNDD NNTIINKKKI EEEEDETNFD TSLIPKLGHE
160 170 180 190 200
DKDELESDHY ITIWGNGIRN YKNCNMSSIG FSEMYNQQKI VLISTGAIHS
210 220 230 240 250
SFITDQGNLY TFGDGLLGKL GHGNLESYSS PKLVEFFQTK PSLRVVSIAN
260 270 280 290 300
GGKHSLALTI CGKVYSWGGN DSCQLGLGNG SSSSYYSLPQ LINFNISYNN
310 320 330 340 350
NNNNNNNNST NNNNNNNNDG AQQQFSLSQN SSSNNNKIKI VKLSCGTNRS
360 370 380 390 400
AVITDKGLLF TFGRGDHGRL GLGEQSLLMQ STPKLVQSLQ GHFIIDMSSG
410 420 430 440 450
GGHSLVLTNK GLVFSFGRND QGQLGIGCFS NQQTIPKQIQ WFQTSQQQQQ
460 470 480 490 500
QPINIIKVSA GGYHSIAISD NNDTYAWGRS DYGVLGTSID VQGDRNLPVL
510 520 530 540 550
INSNSVVVDN VKFIDVSSGF QHNVAMSIDG SLYSWGCNAG QRLGFKSDEN
560 570 580 590 600
QLTPKKCFIN SKDSKPLLFT CGEIITIIVE KRFKEPIIKT ELQLPSSTQS
610 620 630 640 650
QQQTELSLPS SVNSSSDSNF NKSIIDNSST TTIIKQTNNN IKSTTTTIIT
660 670 680 690 700
RPSSPTPSFL SLANEGKDLL NSTQSNFIEW MTLISKSKGL LNLIQMKATS
710 720 730 740 750
SLPNLGLSIE KKNKDFDDIN RQLKLLVNSN LSLSPLPDNI QSEIDRLVLS
760 770 780 790 800
RNQLGLGLVS EYQTSIDYWL EIKQQKDLTF LNLSKLLNLS TITTTTTSNT
810 820 830 840 850
TTTTTATTTT TTTTTTNLIN KKVLVHQDEK QQQREKSETE LEEEQDEEEE
860 870 880 890 900
DSEIKNGTLT AIEIQQQSFY LVERLNQGLG NFCNNIMDST TMVQPLTTAT
910 920 930 940 950
ASSTTATATA TTTTANTTNS SGIINKNFGE SLRLSMEEIQ LIVLETQKYA
960 970 980 990 1000
IKYHSLLSQQ LQQCDDLINI HRGKLVEVQD FLNKSKLAQS LLEQREKLKS
1010 1020 1030 1040 1050
DYRFCKRNSI ELSKKIEVIE LDYDQNLCDD DDNNHENNSV NNNSNNNNNN
1060 1070 1080 1090 1100
NNNNNNNNNN NNNNNNNIDN NINSNSINDS SNNNNNNNNI EKLKNELIKL
1110 1120 1130 1140 1150
KKDEQKLLSN QQEINELIIE ILDKYVPEFK IKLRANDKIS SRIKDTGLLV
1160 1170 1180 1190 1200
TDRKFQHYDI IKTLSTHPHN VYLANFNDQL VVLKEFGIGD AFGKQIFERQ
1210 1220 1230 1240 1250
VSLLKQMNHK CIMPIQAVFY DRNAFMQMEY ISGGNLLDWC RNNNNDNENN
1260 1270 1280 1290 1300
KRRQPWEIQK IFQQIIQAIA YMHSNCIIHR DLKLENVLIR QDGTPVISDF
1310 1320 1330 1340 1350
DLSKDISANV NVTVFNINGG TELYKAPEMK EQNVKGSYST DIWAFGVMLY
1360 1370 1380 1390 1400
KCIFQFVNNN NNGNNGKNNN SDGNENDNNN NNNFLIIREP FLLPEENNLP
1410 1420 1430 1440 1450
LPANHSDQRL ISLLSSIFQR NPKLRPTAHQ IAVHPYFVTS LVEDLLSSRT
1460 1470 1480 1490 1500
LIDCREKIAA FRAHISSLSE MAEEMSESLQ LTVRREHLVL DFFQFFFKKI
1510 1520 1530 1540 1550
ESNKLFCRLE VSFQGEKGLD LGGLSSEMYS LLFSDNQIID NSNNSNNSVS
1560 1570 1580 1590 1600
YSIPKNSLFS KKFNLFENSG TESPFYLLNS NDLFNNNNNN NEENNNNNNN
1610 1620 1630 1640 1650
NNNNNNNNNN NNNNNNNNNN NNNNNNEENP LLILKNEFTI FKILGKIFLK
1660 1670 1680 1690 1700
SIIDGKPIPD CFPTSFFKYL LGVKVNLRDL EIYDPQLAQS FKKVLVLDNI
1710 1720 1730 1740 1750
EEYLSTTFEG LIEGGESIPV TDLNKEEFIQ RNIERVLVGC RQSKLEAFKS
1760 1770 1780 1790 1800
GFMSIDSLNA HFALFSPTEL QLLMCGNTLV DSSVLQKNFK FIGFPDTSST
1810 1820 1830 1840 1850
PKDFRRAVDE MNQDEIRLFL RFVTGMVALP LSGFEKSISI IQVPLSQKLP
1860 1870 1880
CAHTCSYQLD LPDYNDFDTT KKKLIKMLEY VDGFAFI
Length:1,887
Mass (Da):213,011
Last modified:June 1, 2003 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i6E0D63ED31793F65
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AAFI02000015 Genomic DNA Translation: EAL69217.1

NCBI Reference Sequences

More...
RefSeqi
XP_643080.1, XM_637988.1

Genome annotation databases

Ensembl protists genome annotation project

More...
EnsemblProtistsi
EAL69217; EAL69217; DDB_G0276527

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
8620484

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
ddi:DDB_G0276527

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAFI02000015 Genomic DNA Translation: EAL69217.1
RefSeqiXP_643080.1, XM_637988.1

3D structure databases

SMRiQ8SSY6
ModBaseiSearch...

Protein-protein interaction databases

STRINGi44689.DDB0219986

Proteomic databases

PaxDbiQ8SSY6
PRIDEiQ8SSY6

Genome annotation databases

EnsemblProtistsiEAL69217; EAL69217; DDB_G0276527
GeneIDi8620484
KEGGiddi:DDB_G0276527

Organism-specific databases

dictyBaseiDDB_G0276527

Phylogenomic databases

eggNOGiENOG410INH6 Eukaryota
KOG0586 Eukaryota
KOG0941 Eukaryota
COG5021 LUCA
COG5184 LUCA
ENOG410XNQ0 LUCA
InParanoidiQ8SSY6
OMAiNAHFALF

Enzyme and pathway databases

UniPathwayiUPA00143
ReactomeiR-DDI-983168 Antigen processing: Ubiquitination & Proteasome degradation

Miscellaneous databases

Protein Ontology

More...
PROi
PR:Q8SSY6

Family and domain databases

Gene3Di2.130.10.30, 2 hits
InterProiView protein in InterPro
IPR000569 HECT_dom
IPR035983 Hect_E3_ubiquitin_ligase
IPR011009 Kinase-like_dom_sf
IPR000719 Prot_kinase_dom
IPR009091 RCC1/BLIP-II
IPR000408 Reg_chr_condens
IPR008271 Ser/Thr_kinase_AS
PfamiView protein in Pfam
PF00632 HECT, 1 hit
PF00069 Pkinase, 1 hit
PF00415 RCC1, 6 hits
PRINTSiPR00633 RCCNDNSATION
SMARTiView protein in SMART
SM00119 HECTc, 1 hit
SM00220 S_TKc, 1 hit
SUPFAMiSSF50985 SSF50985, 1 hit
SSF56112 SSF56112, 1 hit
SSF56204 SSF56204, 1 hit
PROSITEiView protein in PROSITE
PS50237 HECT, 1 hit
PS50011 PROTEIN_KINASE_DOM, 1 hit
PS00108 PROTEIN_KINASE_ST, 1 hit
PS00626 RCC1_2, 2 hits
PS50012 RCC1_3, 6 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiSPKUL_DICDI
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q8SSY6
Secondary accession number(s): Q551N9
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: June 1, 2003
Last modified: October 16, 2019
This is version 107 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Dictyostelium discoideum
    Dictyostelium discoideum: entries, gene names and cross-references to dictyBase
  3. PATHWAY comments
    Index of metabolic and biosynthesis pathways
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