UniProtKB - Q8S3C9 (DRP1D_ARATH)
Protein
Dynamin-related protein 1D
Gene
DRP1D
Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Functioni
Putative microtubule-associated force-producing protein.By similarity
Regions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Nucleotide bindingi | 42 – 49 | GTPSequence analysis | 8 | |
Nucleotide bindingi | 143 – 147 | GTPBy similarity | 5 | |
Nucleotide bindingi | 212 – 215 | GTPBy similarity | 4 |
GO - Molecular functioni
- GTPase activity Source: GO_Central
- GTP binding Source: UniProtKB-KW
- microtubule binding Source: GO_Central
GO - Biological processi
- mitochondrial fission Source: GO_Central
Keywordsi
Molecular function | Hydrolase, Motor protein |
Ligand | GTP-binding, Nucleotide-binding |
Names & Taxonomyi
Protein namesi | Recommended name: Dynamin-related protein 1DAlternative name(s): Dynamin-like protein D Dynamin-like protein DLP3 |
Gene namesi | Name:DRP1D Synonyms:ADL1D, DLP3 Ordered Locus Names:At2g44590 ORF Names:F16B22.8 |
Organismi | Arabidopsis thaliana (Mouse-ear cress) |
Taxonomic identifieri | 3702 [NCBI] |
Taxonomic lineagei | Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliopsida › eudicotyledons › Gunneridae › Pentapetalae › rosids › malvids › Brassicales › Brassicaceae › Camelineae › Arabidopsis |
Proteomesi |
|
Organism-specific databases
Araporti | AT2G44590 |
TAIRi | locus:2042371, AT2G44590 |
Subcellular locationi
Cytoplasm and Cytosol
- Cytoplasm By similarity
Cytoskeleton
- cytoskeleton By similarity
Note: Microtubule-associated.By similarity
Cytoskeleton
- microtubule Source: UniProtKB-KW
Other locations
Keywords - Cellular componenti
Cytoplasm, Cytoskeleton, MicrotubulePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000206580 | 1 – 612 | Dynamin-related protein 1DAdd BLAST | 612 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Modified residuei | 1 | N-acetylmethionineBy similarity | 1 |
Keywords - PTMi
AcetylationProteomic databases
PaxDbi | Q8S3C9 |
PRIDEi | Q8S3C9 |
ProteomicsDBi | 224362 [Q8S3C9-1] |
Expressioni
Gene expression databases
ExpressionAtlasi | Q8S3C9, baseline and differential |
Genevisiblei | Q8S3C9, AT |
Interactioni
GO - Molecular functioni
- microtubule binding Source: GO_Central
Protein-protein interaction databases
STRINGi | 3702.AT2G44590.3 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 32 – 301 | Dynamin-type GPROSITE-ProRule annotationAdd BLAST | 270 | |
Domaini | 520 – 612 | GEDPROSITE-ProRule annotationAdd BLAST | 93 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 42 – 49 | G1 motifPROSITE-ProRule annotation | 8 | |
Regioni | 68 – 70 | G2 motifPROSITE-ProRule annotation | 3 | |
Regioni | 143 – 146 | G3 motifPROSITE-ProRule annotation | 4 | |
Regioni | 212 – 215 | G4 motifPROSITE-ProRule annotation | 4 | |
Regioni | 242 – 245 | G5 motifPROSITE-ProRule annotation | 4 |
Sequence similaritiesi
Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.PROSITE-ProRule annotation
Phylogenomic databases
eggNOGi | KOG0446, Eukaryota |
HOGENOMi | CLU_008964_5_3_1 |
InParanoidi | Q8S3C9 |
OMAi | EHGTDEY |
PhylomeDBi | Q8S3C9 |
Family and domain databases
CDDi | cd08771, DLP_1, 1 hit |
InterProi | View protein in InterPro IPR001401, Dynamin_GTPase IPR019762, Dynamin_GTPase_CS IPR022812, Dynamin_SF IPR000375, Dynamin_stalk IPR030381, G_DYNAMIN_dom IPR003130, GED IPR020850, GED_dom IPR027417, P-loop_NTPase |
PANTHERi | PTHR11566, PTHR11566, 1 hit |
Pfami | View protein in Pfam PF01031, Dynamin_M, 1 hit PF00350, Dynamin_N, 1 hit PF02212, GED, 1 hit |
PRINTSi | PR00195, DYNAMIN |
SMARTi | View protein in SMART SM00053, DYNc, 1 hit SM00302, GED, 1 hit |
SUPFAMi | SSF52540, SSF52540, 1 hit |
PROSITEi | View protein in PROSITE PS00410, G_DYNAMIN_1, 1 hit PS51718, G_DYNAMIN_2, 1 hit PS51388, GED, 1 hit |
s (3)i Sequence
Sequence statusi: Complete.
This entry describes 3 produced by isoformsialternative splicing. AlignAdd to basketIsoform 1 (identifier: Q8S3C9-1) [UniParc]FASTAAdd to basket
Also known as: DLP3a
This isoform has been chosen as the sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry. canonicali
10 20 30 40 50
MESLIVLINT IQRACTVVGD HGGDSNALSS LWEALPSVAV VGGQSSGKSS
60 70 80 90 100
VLESIVGRDF LPRGSGIVTR RPLVLQLHKT ENGTEDNAEF LHLTNKKFTN
110 120 130 140 150
FSLVRKEIED ETDRITGKNK QISSIPIHLS IFSPNVVNLT LIDLPGLTKV
160 170 180 190 200
AVEGQPETIV EDIESMVRSY VEKPNCLILA ISPANQDIAT SDAMKLAKEV
210 220 230 240 250
DPIGDRTFGV LTKLDLMDKG TNALDVINGR SYKLKYPWVG IVNRSQADIN
260 270 280 290 300
KNVDMMVARR KEREYFETSP DYGHLATRMG SEYLAKLLSK LLESVIRSRI
310 320 330 340 350
PSILSLINNN IEELERELDQ LGRPIAIDAG AQLYTILGMC RAFEKIFKEH
360 370 380 390 400
LDGGRPGGAR IYGIFDYNLP TAIKKLPFDR HLSLQSVKRI VSESDGYQPH
410 420 430 440 450
LIAPELGYRR LIEGSLNHFR GPAEASVNAI HLILKELVRK AIAETEELKR
460 470 480 490 500
FPSLQIELVA AANSSLDKFR EESMKSVLRL VDMESSYLTV DFFRKLHVES
510 520 530 540 550
QNMSLSSPTS AIDQYGDGHF RKIASNVAAY IKMVAETLVN TIPKAVVHCQ
560 570 580 590 600
VRQAKLSLLN YFYAQISQSQ GKRLGQLLDE NPALMERRMQ CAKRLELYKK
610
ARDEIDAAVW VR
Alternative sequence
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Alternative sequenceiVSP_012753 | 136 – 152 | Missing in isoform 2 and isoform 3. 2 PublicationsAdd BLAST | 17 | |
Alternative sequenceiVSP_012754 | 570 | Q → QQ in isoform 3. 1 Publication | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AF488807 mRNA Translation: AAL92169.1 AJ304843 mRNA Translation: CAC19658.1 AJ304844 mRNA Translation: CAC19659.1 AC003672 Genomic DNA Translation: AAC27461.1 CP002685 Genomic DNA Translation: AEC10443.1 CP002685 Genomic DNA Translation: AEC10444.1 CP002685 Genomic DNA Translation: AEC10445.1 |
PIRi | T01586 |
RefSeqi | NP_850418.1, NM_180087.1 [Q8S3C9-3] NP_850419.1, NM_180088.3 [Q8S3C9-2] NP_850420.1, NM_180089.2 [Q8S3C9-1] |
Genome annotation databases
EnsemblPlantsi | AT2G44590.1; AT2G44590.1; AT2G44590 [Q8S3C9-3] AT2G44590.2; AT2G44590.2; AT2G44590 [Q8S3C9-2] AT2G44590.3; AT2G44590.3; AT2G44590 [Q8S3C9-1] |
GeneIDi | 819067 |
Gramenei | AT2G44590.1; AT2G44590.1; AT2G44590 [Q8S3C9-3] AT2G44590.2; AT2G44590.2; AT2G44590 [Q8S3C9-2] AT2G44590.3; AT2G44590.3; AT2G44590 [Q8S3C9-1] |
KEGGi | ath:AT2G44590 |
Keywords - Coding sequence diversityi
Alternative splicingSimilar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AF488807 mRNA Translation: AAL92169.1 AJ304843 mRNA Translation: CAC19658.1 AJ304844 mRNA Translation: CAC19659.1 AC003672 Genomic DNA Translation: AAC27461.1 CP002685 Genomic DNA Translation: AEC10443.1 CP002685 Genomic DNA Translation: AEC10444.1 CP002685 Genomic DNA Translation: AEC10445.1 |
PIRi | T01586 |
RefSeqi | NP_850418.1, NM_180087.1 [Q8S3C9-3] NP_850419.1, NM_180088.3 [Q8S3C9-2] NP_850420.1, NM_180089.2 [Q8S3C9-1] |
3D structure databases
SMRi | Q8S3C9 |
ModBasei | Search... |
Protein-protein interaction databases
STRINGi | 3702.AT2G44590.3 |
Proteomic databases
PaxDbi | Q8S3C9 |
PRIDEi | Q8S3C9 |
ProteomicsDBi | 224362 [Q8S3C9-1] |
Genome annotation databases
EnsemblPlantsi | AT2G44590.1; AT2G44590.1; AT2G44590 [Q8S3C9-3] AT2G44590.2; AT2G44590.2; AT2G44590 [Q8S3C9-2] AT2G44590.3; AT2G44590.3; AT2G44590 [Q8S3C9-1] |
GeneIDi | 819067 |
Gramenei | AT2G44590.1; AT2G44590.1; AT2G44590 [Q8S3C9-3] AT2G44590.2; AT2G44590.2; AT2G44590 [Q8S3C9-2] AT2G44590.3; AT2G44590.3; AT2G44590 [Q8S3C9-1] |
KEGGi | ath:AT2G44590 |
Organism-specific databases
Araporti | AT2G44590 |
TAIRi | locus:2042371, AT2G44590 |
Phylogenomic databases
eggNOGi | KOG0446, Eukaryota |
HOGENOMi | CLU_008964_5_3_1 |
InParanoidi | Q8S3C9 |
OMAi | EHGTDEY |
PhylomeDBi | Q8S3C9 |
Miscellaneous databases
PROi | PR:Q8S3C9 |
Gene expression databases
ExpressionAtlasi | Q8S3C9, baseline and differential |
Genevisiblei | Q8S3C9, AT |
Family and domain databases
CDDi | cd08771, DLP_1, 1 hit |
InterProi | View protein in InterPro IPR001401, Dynamin_GTPase IPR019762, Dynamin_GTPase_CS IPR022812, Dynamin_SF IPR000375, Dynamin_stalk IPR030381, G_DYNAMIN_dom IPR003130, GED IPR020850, GED_dom IPR027417, P-loop_NTPase |
PANTHERi | PTHR11566, PTHR11566, 1 hit |
Pfami | View protein in Pfam PF01031, Dynamin_M, 1 hit PF00350, Dynamin_N, 1 hit PF02212, GED, 1 hit |
PRINTSi | PR00195, DYNAMIN |
SMARTi | View protein in SMART SM00053, DYNc, 1 hit SM00302, GED, 1 hit |
SUPFAMi | SSF52540, SSF52540, 1 hit |
PROSITEi | View protein in PROSITE PS00410, G_DYNAMIN_1, 1 hit PS51718, G_DYNAMIN_2, 1 hit PS51388, GED, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | DRP1D_ARATH | |
Accessioni | Q8S3C9Primary (citable) accession number: Q8S3C9 Secondary accession number(s): O80499, Q9FNX3, Q9FNX4 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | February 1, 2005 |
Last sequence update: | February 1, 2005 | |
Last modified: | April 7, 2021 | |
This is version 118 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Plant Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Arabidopsis thaliana
Arabidopsis thaliana: entries and gene names - SIMILARITY comments
Index of protein domains and families