UniProtKB - Q8S341 (PPA7_ARATH)
Protein
Purple acid phosphatase 7
Gene
PAP7
Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Functioni
Catalytic activityi
- EC:3.1.3.2
Cofactori
Protein has several cofactor binding sites:- Fe cationBy similarityNote: Binds 1 Fe cation per subunit.By similarity
- Zn2+By similarityNote: Binds 1 zinc ion per subunit.By similarity
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Metal bindingi | 48 | IronBy similarity | 1 | |
Metal bindingi | 81 | IronBy similarity | 1 | |
Metal bindingi | 81 | ZincBy similarity | 1 | |
Metal bindingi | 84 | IronBy similarity | 1 | |
Metal bindingi | 119 | ZincBy similarity | 1 | |
Metal bindingi | 213 | ZincBy similarity | 1 | |
Active sitei | 222 | Proton donorBy similarity | 1 | |
Metal bindingi | 248 | ZincBy similarity | 1 | |
Metal bindingi | 250 | IronBy similarity | 1 |
GO - Molecular functioni
- acid phosphatase activity Source: TAIR
- ferric iron binding Source: GO_Central
- ferrous iron binding Source: GO_Central
Keywordsi
Molecular function | Hydrolase |
Ligand | Iron, Metal-binding, Zinc |
Enzyme and pathway databases
BioCyci | ARA:AT2G01880-MONOMER |
Names & Taxonomyi
Protein namesi | |
Gene namesi | Name:PAP7 Ordered Locus Names:At2g01880 ORF Names:T23K3.7 |
Organismi | Arabidopsis thaliana (Mouse-ear cress) |
Taxonomic identifieri | 3702 [NCBI] |
Taxonomic lineagei | Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliopsida › eudicotyledons › Gunneridae › Pentapetalae › rosids › malvids › Brassicales › Brassicaceae › Camelineae › Arabidopsis |
Proteomesi |
|
Organism-specific databases
Araporti | AT2G01880 |
TAIRi | locus:2059743, AT2G01880 |
Subcellular locationi
Extracellular region or secreted
- Secreted By similarity
Extracellular region or secreted
- extracellular region Source: UniProtKB-SubCell
Keywords - Cellular componenti
SecretedPTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Signal peptidei | 1 – 24 | Sequence analysisAdd BLAST | 24 | |
ChainiPRO_0000372812 | 25 – 328 | Purple acid phosphatase 7Add BLAST | 304 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Glycosylationi | 56 | N-linked (GlcNAc...) asparagineSequence analysis | 1 |
Keywords - PTMi
GlycoproteinProteomic databases
PaxDbi | Q8S341 |
PRIDEi | Q8S341 |
ProteomicsDBi | 249034 |
Expressioni
Tissue specificityi
Expressed in roots, stems, leaves, flowers and siliques.1 Publication
Gene expression databases
ExpressionAtlasi | Q8S341, baseline and differential |
Genevisiblei | Q8S341, AT |
Interactioni
Subunit structurei
Homodimer.
By similarityProtein-protein interaction databases
BioGRIDi | 122, 1 interactor |
IntActi | Q8S341, 1 interactor |
STRINGi | 3702.AT2G01880.1 |
Family & Domainsi
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 248 – 250 | Substrate bindingBy similarity | 3 |
Sequence similaritiesi
Keywords - Domaini
SignalPhylogenomic databases
eggNOGi | KOG2679, Eukaryota |
HOGENOMi | CLU_043332_3_0_1 |
InParanoidi | Q8S341 |
OMAi | HHPYLNN |
OrthoDBi | 711825at2759 |
PhylomeDBi | Q8S341 |
Family and domain databases
CDDi | cd07378, MPP_ACP5, 1 hit |
Gene3Di | 3.60.21.10, 1 hit |
InterProi | View protein in InterPro IPR024927, Acid_PPase IPR004843, Calcineurin-like_PHP_ApaH IPR029052, Metallo-depent_PP-like |
Pfami | View protein in Pfam PF00149, Metallophos, 1 hit |
PIRSFi | PIRSF000898, Acid_Ptase_5, 1 hit |
i Sequence
Sequence statusi: Complete.
: The displayed sequence is further processed into a mature form. Sequence processingi
Q8S341-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MKMHVCFSVI LMFLSIFFIN GALSKLERLK HPVKKKSDGS LSFLVIGDWG
60 70 80 90 100
RKGGFNQSLV AHQMGVVGEK LDIDFVISVG DNFYDDGLKG VNDPSFEASF
110 120 130 140 150
SHIYTHPSLQ KQWYSVLGNH DYRGNVEAQL SKVLTQKDWR WFCRRSFVLS
160 170 180 190 200
SGMVDFFFAD TNPFVEKYFT EPEDHTYDWR NVLPRNKYIS NLLHDLDLEI
210 220 230 240 250
KKSRATWKFV VGHHGIKTAG NHGVTQELVD QLLPILEENK VDLYINGHDH
260 270 280 290 300
CLQHIGSHGK TQFLTSGGGS KAWRGHVQPW DPKELKLYYD GQGFMSLHIT
310 320
HSKAKFIYYD VSGNVLHRSS LSKRSAHL
Sequence cautioni
The sequence AAD21780 differs from that shown. Reason: Erroneous gene model prediction.Curated
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sequence conflicti | 317 | H → L in BAC43423 (PubMed:11910074).Curated | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AF492659 mRNA Translation: AAM15908.1 AC007069 Genomic DNA Translation: AAD21780.1 Sequence problems. CP002685 Genomic DNA Translation: AEC05511.1 AK118834 mRNA Translation: BAC43423.1 BT026449 mRNA Translation: ABH04556.1 |
PIRi | C84430 |
RefSeqi | NP_178297.2, NM_126249.5 |
Genome annotation databases
EnsemblPlantsi | AT2G01880.1; AT2G01880.1; AT2G01880 |
GeneIDi | 814719 |
Gramenei | AT2G01880.1; AT2G01880.1; AT2G01880 |
KEGGi | ath:AT2G01880 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AF492659 mRNA Translation: AAM15908.1 AC007069 Genomic DNA Translation: AAD21780.1 Sequence problems. CP002685 Genomic DNA Translation: AEC05511.1 AK118834 mRNA Translation: BAC43423.1 BT026449 mRNA Translation: ABH04556.1 |
PIRi | C84430 |
RefSeqi | NP_178297.2, NM_126249.5 |
3D structure databases
SMRi | Q8S341 |
ModBasei | Search... |
Protein-protein interaction databases
BioGRIDi | 122, 1 interactor |
IntActi | Q8S341, 1 interactor |
STRINGi | 3702.AT2G01880.1 |
Proteomic databases
PaxDbi | Q8S341 |
PRIDEi | Q8S341 |
ProteomicsDBi | 249034 |
Genome annotation databases
EnsemblPlantsi | AT2G01880.1; AT2G01880.1; AT2G01880 |
GeneIDi | 814719 |
Gramenei | AT2G01880.1; AT2G01880.1; AT2G01880 |
KEGGi | ath:AT2G01880 |
Organism-specific databases
Araporti | AT2G01880 |
TAIRi | locus:2059743, AT2G01880 |
Phylogenomic databases
eggNOGi | KOG2679, Eukaryota |
HOGENOMi | CLU_043332_3_0_1 |
InParanoidi | Q8S341 |
OMAi | HHPYLNN |
OrthoDBi | 711825at2759 |
PhylomeDBi | Q8S341 |
Enzyme and pathway databases
BioCyci | ARA:AT2G01880-MONOMER |
Miscellaneous databases
PROi | PR:Q8S341 |
Gene expression databases
ExpressionAtlasi | Q8S341, baseline and differential |
Genevisiblei | Q8S341, AT |
Family and domain databases
CDDi | cd07378, MPP_ACP5, 1 hit |
Gene3Di | 3.60.21.10, 1 hit |
InterProi | View protein in InterPro IPR024927, Acid_PPase IPR004843, Calcineurin-like_PHP_ApaH IPR029052, Metallo-depent_PP-like |
Pfami | View protein in Pfam PF00149, Metallophos, 1 hit |
PIRSFi | PIRSF000898, Acid_Ptase_5, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | PPA7_ARATH | |
Accessioni | Q8S341Primary (citable) accession number: Q8S341 Secondary accession number(s): Q8GWH8, Q9SIS6 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | May 5, 2009 |
Last sequence update: | June 1, 2002 | |
Last modified: | December 2, 2020 | |
This is version 122 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Plant Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Arabidopsis thaliana
Arabidopsis thaliana: entries and gene names - SIMILARITY comments
Index of protein domains and families