UniProtKB - Q8RY67 (WAKLO_ARATH)
Protein
Wall-associated receptor kinase-like 14
Gene
WAKL14
Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Functioni
Serine/threonine-protein kinase that may function as a signaling receptor of extracellular matrix component.
Caution
Lacks the calcium-binding EGF-like domain which is a conserved feature of the wall-associated receptor kinase family.Curated
Catalytic activityi
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Binding sitei | 376 | ATPPROSITE-ProRule annotation | 1 | |
Active sitei | 472 | Proton acceptorPROSITE-ProRule annotation | 1 |
Regions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Nucleotide bindingi | 354 – 362 | ATPPROSITE-ProRule annotation | 9 |
GO - Molecular functioni
- ATP binding Source: UniProtKB-KW
- protein serine/threonine kinase activity Source: GO_Central
GO - Biological processi
- cell surface receptor signaling pathway Source: GO_Central
- protein phosphorylation Source: GO_Central
Keywordsi
Molecular function | Kinase, Serine/threonine-protein kinase, Transferase |
Ligand | ATP-binding, Nucleotide-binding |
Names & Taxonomyi
Protein namesi | |
Gene namesi | Name:WAKL14 Ordered Locus Names:At2g23450 ORF Names:F26B6.10 |
Organismi | Arabidopsis thaliana (Mouse-ear cress) |
Taxonomic identifieri | 3702 [NCBI] |
Taxonomic lineagei | Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliopsida › eudicotyledons › Gunneridae › Pentapetalae › rosids › malvids › Brassicales › Brassicaceae › Camelineae › Arabidopsis |
Proteomesi |
|
Organism-specific databases
Araporti | AT2G23450 |
TAIRi | locus:2046728, AT2G23450 |
Subcellular locationi
Other locations
- Membrane Curated; Single-pass type I membrane protein Curated
Plasma Membrane
- plasma membrane Source: GO_Central
Other locations
- integral component of membrane Source: UniProtKB-KW
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Topological domaini | 43 – 285 | ExtracellularSequence analysisAdd BLAST | 243 | |
Transmembranei | 286 – 306 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 307 – 708 | CytoplasmicSequence analysisAdd BLAST | 402 |
Keywords - Cellular componenti
MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Signal peptidei | 1 – 42 | Sequence analysisAdd BLAST | 42 | |
ChainiPRO_0000253319 | 43 – 708 | Wall-associated receptor kinase-like 14Add BLAST | 666 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Glycosylationi | 43 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Glycosylationi | 88 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Glycosylationi | 101 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Glycosylationi | 131 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Glycosylationi | 158 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Glycosylationi | 167 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Glycosylationi | 184 | N-linked (GlcNAc...) asparagineSequence analysis | 1 |
Keywords - PTMi
GlycoproteinProteomic databases
PaxDbi | Q8RY67 |
PRIDEi | Q8RY67 |
ProteomicsDBi | 242744 |
Expressioni
Gene expression databases
ExpressionAtlasi | Q8RY67, baseline and differential |
Genevisiblei | Q8RY67, AT |
Interactioni
Protein-protein interaction databases
BioGRIDi | 2229, 7 interactors |
IntActi | Q8RY67, 7 interactors |
STRINGi | 3702.AT2G23450.2 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 348 – 629 | Protein kinasePROSITE-ProRule annotationAdd BLAST | 282 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 302 – 305 | Poly-Phe | 4 |
Sequence similaritiesi
Keywords - Domaini
Signal, Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | KOG1187, Eukaryota |
HOGENOMi | CLU_000288_43_5_1 |
InParanoidi | Q8RY67 |
OMAi | GANAMCT |
OrthoDBi | 684563at2759 |
PhylomeDBi | Q8RY67 |
Family and domain databases
InterProi | View protein in InterPro IPR011009, Kinase-like_dom_sf IPR000719, Prot_kinase_dom IPR017441, Protein_kinase_ATP_BS IPR008271, Ser/Thr_kinase_AS |
Pfami | View protein in Pfam PF00069, Pkinase, 1 hit |
SMARTi | View protein in SMART SM00220, S_TKc, 1 hit |
SUPFAMi | SSF56112, SSF56112, 1 hit |
PROSITEi | View protein in PROSITE PS01186, EGF_2, 1 hit PS00107, PROTEIN_KINASE_ATP, 1 hit PS50011, PROTEIN_KINASE_DOM, 1 hit PS00108, PROTEIN_KINASE_ST, 1 hit |
i Sequence
Sequence statusi: Complete.
: The displayed sequence is further processed into a mature form. Sequence processingi
Q8RY67-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MLRSIFDFNQ RSTKMVMISH KLDLILVFII VIGGSIFRRV SANFTVPCNG
60 70 80 90 100
RCGGLTLPYP FGFSNGCSIR FDCSAAEKPM IGDFSVQNVT ENSIFVGLSH
110 120 130 140 150
NCTRKIEDMN PLFGENFAPT SENSFLMENC NRTTDGCSIK QKFLENVLKL
160 170 180 190 200
KSCDATGNIS CFSLDSNSSS KNSAKFFSMK TLRNSSCSLL FSSIAFESVG
210 220 230 240 250
VNAGIALEFE RVRLGWWLKG GCESGTCAAN TDCTDVETPH GYAGHRCSCL
260 270 280 290 300
DGFHGDGYTN PCQRALPECR GSKLVWRHCR SNLITIVGGT VGGAFLLAAL
310 320 330 340 350
AFFFFCKRRR STPLRSHLSA KRLLSEAAGN SSVAFFPYKE IEKATDGFSE
360 370 380 390 400
KQKLGIGAYG TVYRGKLQND EWVAIKRLRH RDSESLDQVM NEIKLLSSVS
410 420 430 440 450
HPNLVRLLGC CIEQGDPVLV YEYMPNGTLS EHLQRDRGSG LPWTLRLTVA
460 470 480 490 500
TQTAKAIAYL HSSMNPPIYH RDIKSTNILL DYDFNSKVAD FGLSRLGMTE
510 520 530 540 550
SSHISTAPQG TPGYLDPQYH QCFHLSDKSD VYSFGVVLAE IITGLKVVDF
560 570 580 590 600
TRPHTEINLA ALAVDKIGSG CIDEIIDPIL DLDLDAWTLS SIHTVAELAF
610 620 630 640 650
RCLAFHSDMR PTMTEVADEL EQIRLSGWIP SMSLDSPAGS LRSSDRGSER
660 670 680 690 700
SVKQSSIGSR RVVIPQKQPD CLASVEEISD SSPISVQDPW LSAQSSPSTN
TLLGNIPR
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sequence conflicti | 89 | V → A in AAL91622 (PubMed:14593172).Curated | 1 | |
Sequence conflicti | 89 | V → A in AAN33192 (PubMed:14593172).Curated | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC003040 Genomic DNA Translation: AAC23760.2 CP002685 Genomic DNA Translation: AEC07456.1 CP002685 Genomic DNA Translation: AEC07457.1 AY075606 mRNA Translation: AAL91622.1 BT000817 mRNA Translation: AAN33192.1 |
PIRi | T01134 |
RefSeqi | NP_565552.1, NM_127909.2 NP_850041.1, NM_179710.3 |
Genome annotation databases
EnsemblPlantsi | AT2G23450.1; AT2G23450.1; AT2G23450 AT2G23450.2; AT2G23450.2; AT2G23450 |
GeneIDi | 816877 |
Gramenei | AT2G23450.1; AT2G23450.1; AT2G23450 AT2G23450.2; AT2G23450.2; AT2G23450 |
KEGGi | ath:AT2G23450 |
Similar proteinsi
Cross-referencesi
Web resourcesi
PlantP kinase Classification PPC |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC003040 Genomic DNA Translation: AAC23760.2 CP002685 Genomic DNA Translation: AEC07456.1 CP002685 Genomic DNA Translation: AEC07457.1 AY075606 mRNA Translation: AAL91622.1 BT000817 mRNA Translation: AAN33192.1 |
PIRi | T01134 |
RefSeqi | NP_565552.1, NM_127909.2 NP_850041.1, NM_179710.3 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
BioGRIDi | 2229, 7 interactors |
IntActi | Q8RY67, 7 interactors |
STRINGi | 3702.AT2G23450.2 |
Proteomic databases
PaxDbi | Q8RY67 |
PRIDEi | Q8RY67 |
ProteomicsDBi | 242744 |
Genome annotation databases
EnsemblPlantsi | AT2G23450.1; AT2G23450.1; AT2G23450 AT2G23450.2; AT2G23450.2; AT2G23450 |
GeneIDi | 816877 |
Gramenei | AT2G23450.1; AT2G23450.1; AT2G23450 AT2G23450.2; AT2G23450.2; AT2G23450 |
KEGGi | ath:AT2G23450 |
Organism-specific databases
Araporti | AT2G23450 |
TAIRi | locus:2046728, AT2G23450 |
Phylogenomic databases
eggNOGi | KOG1187, Eukaryota |
HOGENOMi | CLU_000288_43_5_1 |
InParanoidi | Q8RY67 |
OMAi | GANAMCT |
OrthoDBi | 684563at2759 |
PhylomeDBi | Q8RY67 |
Miscellaneous databases
PROi | PR:Q8RY67 |
Gene expression databases
ExpressionAtlasi | Q8RY67, baseline and differential |
Genevisiblei | Q8RY67, AT |
Family and domain databases
InterProi | View protein in InterPro IPR011009, Kinase-like_dom_sf IPR000719, Prot_kinase_dom IPR017441, Protein_kinase_ATP_BS IPR008271, Ser/Thr_kinase_AS |
Pfami | View protein in Pfam PF00069, Pkinase, 1 hit |
SMARTi | View protein in SMART SM00220, S_TKc, 1 hit |
SUPFAMi | SSF56112, SSF56112, 1 hit |
PROSITEi | View protein in PROSITE PS01186, EGF_2, 1 hit PS00107, PROTEIN_KINASE_ATP, 1 hit PS50011, PROTEIN_KINASE_DOM, 1 hit PS00108, PROTEIN_KINASE_ST, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | WAKLO_ARATH | |
Accessioni | Q8RY67Primary (citable) accession number: Q8RY67 Secondary accession number(s): O80461 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | October 17, 2006 |
Last sequence update: | October 17, 2006 | |
Last modified: | August 12, 2020 | |
This is version 123 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Plant Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Arabidopsis thaliana
Arabidopsis thaliana: entries and gene names - SIMILARITY comments
Index of protein domains and families