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UniProtKB - Q8RUW5 (SCP8_ARATH)

Entry version 119 (12 Aug 2020)
Sequence version 2 (06 Feb 2007)
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Protein

Serine carboxypeptidase-like 8

Gene

SCPL8

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Involved in plants secondary metabolism. Functions as acyltransferase to form the sinapate ester sinapoylmalate. Also capable of catalyzing the formation of 1,2-bis-O-sinapoyl beta-D-glucoside.5 Publications

Miscellaneous

In cv. Pna-10, this protein SCP8 and the adjacent SCP10 are not present due to a natural 13-kb deletion (PubMed:19969522).1 Publication

Caution

Was classified as a serine carboxypeptidase-like (SCPL) protein solely on the basis of the overall sequence similarity (PubMed:15908604) but it has been shown that it belongs to a class of enzymes that catalyze acyltransferase reactions (PubMed:17600138).2 Publications

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes regulatory mechanisms for enzymes, transporters or microbial transcription factors, and reports the components which regulate (by activation or inhibition) the reaction.<p><a href='/help/activity_regulation' target='_top'>More...</a></p>Activity regulationi

95% inhibition by diisopropyl fluorophosphate (DFP) and 30% by phenylmethylsulfonyl fluoride (PMSF).2 Publications

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section is used for enzymes and indicates the residues directly involved in catalysis.<p><a href='/help/act_site' target='_top'>More...</a></p>Active sitei173By similarity1
Active sitei358By similarity1
Active sitei411By similarity1

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionAcyltransferase, Transferase

Enzyme and pathway databases

BioCyc Collection of Pathway/Genome Databases

More...BioCyci		ARA:AT2G22990-MONOMER

BRENDA Comprehensive Enzyme Information System

More...BRENDAi		2.3.1.92, 399

Protein family/group databases

ESTHER database of the Alpha/Beta-hydrolase fold superfamily of proteins

More...ESTHERi		arath-SCP8, Carboxypeptidase_S10

MEROPS protease database

More...MEROPSi		S10.A14

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Serine carboxypeptidase-like 8
Alternative name(s):
Protein SINAPOYLGLUCOSE ACCUMULATOR 1
Sinapoylglucose--malate O-sinapoyltransferase (EC:2.3.1.92)
Short name:
SMT
Sinapoylglucose--sinapoylglucose O-sinapoyltransferase (EC:2.3.1.103)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:SCPL8
Synonyms:SMT, SNG1
Ordered Locus Names:At2g22990
ORF Names:F21P24.5, T20K9.18
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiArabidopsis thaliana (Mouse-ear cress)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri3702 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliopsida › eudicotyledons › Gunneridae › Pentapetalae › rosids › malvids › Brassicales › Brassicaceae › Camelineae › Arabidopsis
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000006548 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 2

Organism-specific databases

Arabidopsis Information Portal

More...Araporti		AT2G22990

The Arabidopsis Information Resource

More...TAIRi		locus:2045374, AT2G22990

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Vacuole

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

<p>This subsection of the 'Pathology and Biotech' section describes the in vivo effects caused by ablation of the gene (or one or more transcripts) coding for the protein described in the entry. This includes gene knockout and knockdown, provided experiments have been performed in the context of a whole organism or a specific tissue, and not at the single-cell level.<p><a href='/help/disruption_phenotype' target='_top'>More...</a></p>Disruption phenotypei

Plants do not contain sinapoylmalate and accumulate its biosynthetic precursor, sinapoylglucose.1 Publication

Mutagenesis

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/manual/pathology%5Fand%5Fbiotech%5Fsection">'Pathology and Biotech'</a> section describes the effect of the experimental mutation of one or more amino acid(s) on the biological properties of the protein.<p><a href='/help/mutagen' target='_top'>More...</a></p>Mutagenesisi73N → A: 87% reduction of activity. 1 Publication1
Mutagenesisi172 – 175DSYS → ESYA: 85% reduction of activity. 1 Publication4
Mutagenesisi173S → A: Total loss of activity. 1 Publication1
Mutagenesisi268K → E: 25% reduction of activity. 1 Publication1
Mutagenesisi272H → D: 78% reduction of activity. 1 Publication1
Mutagenesisi322R → E: 99% reduction of activity. 1 Publication1
Mutagenesisi358D → A: 80% reduction of activity. 1 Publication1
Mutagenesisi411H → A: Total loss of activity. 1 Publication1

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 192 PublicationsAdd BLAST19
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_000027462220 – 433Serine carboxypeptidase-like 8Add BLAST414

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi78 ↔ 323By similarity
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi99N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi241 ↔ 255By similarity
Disulfide bondi279 ↔ 289By similarity
Glycosylationi283N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi324N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi342N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi418N-linked (GlcNAc...) asparagineSequence analysis1

<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM/processing</a> section describes post-translational modifications (PTMs). This subsection <strong>complements</strong> the information provided at the sequence level or describes modifications for which <strong>position-specific data is not yet available</strong>.<p><a href='/help/post-translational_modification' target='_top'>More...</a></p>Post-translational modificationi

N-glycosylated.1 Publication

Keywords - PTMi

Disulfide bond, Glycoprotein

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		Q8RUW5

PRoteomics IDEntifications database

More...PRIDEi		Q8RUW5

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		232855 [Q8RUW5-1]

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Highly expressed in seedlings. Expressed in leaves, stems, flowers and siliques, and at low levels in roots.3 Publications

Gene expression databases

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		Q8RUW5, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		Q8RUW5, AT

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...STRINGi		3702.AT2G22990.3

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		Q8RUW5

Database of comparative protein structure models

More...ModBasei		Search...

Protein Data Bank in Europe - Knowledge Base

More...PDBe-KBi		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the peptidase S10 family.Curated

Keywords - Domaini

Signal

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG1282, Eukaryota

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_008523_0_1_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q8RUW5

KEGG Orthology (KO)

More...KOi		K09757

Database of Orthologous Groups

More...OrthoDBi		607679at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		Q8RUW5

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		3.40.50.1820, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR029058, AB_hydrolase
IPR001563, Peptidase_S10

The PANTHER Classification System

More...PANTHERi		PTHR11802, PTHR11802, 1 hit

Pfam protein domain database

More...Pfami		View protein in Pfam
PF00450, Peptidase_S10, 1 hit

Protein Motif fingerprint database; a protein domain database

More...PRINTSi		PR00724, CRBOXYPTASEC

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF53474, SSF53474, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

This entry describes 2 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform. This section is only present in reviewed entries, i.e. in UniProtKB/Swiss-Prot.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 4 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q8RUW5-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MSLKIKFLLL LVLYHHVDSA SIVKFLPGFE GPLPFELETG YIGIGEDENV 
        60         70         80         90        100
QFFYYFIKSE NNPKEDPLLI WLNGGPGCSC LGGIIFENGP VGLKFEVFNG 
       110        120        130        140        150
SAPSLFSTTY SWTKMANIIF LDQPVGSGFS YSKTPIDKTG DISEVKRTHE 
       160        170        180        190        200
FLQKWLSRHP QYFSNPLYVV GDSYSGMIVP ALVQEISQGN YICCEPPINL 
       210        220        230        240        250
QGYMLGNPVT YMDFEQNFRI PYAYGMGLIS DEIYEPMKRI CNGNYYNVDP 
       260        270        280        290        300
SNTQCLKLTE EYHKCTAKIN IHHILTPDCD VTNVTSPDCY YYPYHLIECW 
       310        320        330        340        350
ANDESVREAL HIEKGSKGKW ARCNRTIPYN HDIVSSIPYH MNNSISGYRS 
       360        370        380        390        400
LIYSGDHDIA VPFLATQAWI RSLNYSPIHN WRPWMINNQI AGYTRAYSNK 
       410        420        430 
MTFATIKGGG HTAEYRPNET FIMFQRWISG QPL
Length:433
Mass (Da):49,439
Last modified:February 6, 2007 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i67234085A5FBAF0C
GO
Isoform 2 (identifier: Q8RUW5-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     408-433: GGGHTAEYRPNETFIMFQRWISGQPL → ASVDTRQSID...NIHVKRSCLC

Note: May be due to a competing donor splice site.Curated
Show »
Length:458
Mass (Da):52,122
Checksum:iDC1C8BB0FF1E94E8
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A8MQW0A8MQW0_ARATH
Sinapoylglucose 1
SNG1 MALATE SINAPOYLTRANSFERASE, SCPL8, SERINE CARBOXYPEPTIDASE-LIKE 8, sinapoylglucose 1, At2g22990
424Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A8MR78A8MR78_ARATH
Sinapoylglucose 1
SNG1 MALATE SINAPOYLTRANSFERASE, SCPL8, SERINE CARBOXYPEPTIDASE-LIKE 8, sinapoylglucose 1, At2g22990
416Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F4IKK4F4IKK4_ARATH
Sinapoylglucose 1
SNG1 MALATE SINAPOYLTRANSFERASE, SCPL8, SERINE CARBOXYPEPTIDASE-LIKE 8, sinapoylglucose 1, At2g22990
319Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
Q3EBW0Q3EBW0_ARATH
Sinapoylglucose 1
SNG1 MALATE SINAPOYLTRANSFERASE, SCPL8, SERINE CARBOXYPEPTIDASE-LIKE 8, sinapoylglucose 1, At2g22990
319Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAC17816 differs from that shown. Reason: Erroneous gene model prediction.Curated
The sequence AAK32769 differs from that shown. Reason: Frameshift.Curated
The sequence AAM15006 differs from that shown. Reason: Erroneous gene model prediction.Curated
The sequence AAN28819 differs from that shown. Reason: Erroneous termination. Truncated C-terminus.Curated

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_027464408 – 433GGGHT…SGQPL → ASVDTRQSIDQTRPLSCSKG GSVANPCNKRLMTFTYNYLP TNIHVKRSCLC in isoform 2. CuratedAdd BLAST26

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AF275313 mRNA Translation: AAF78760.1
AC004401 Genomic DNA Translation: AAC17816.2 Sequence problems.
AC004786 Genomic DNA Translation: AAM15006.1 Sequence problems.
CP002685 Genomic DNA Translation: AEC07390.1
CP002685 Genomic DNA Translation: AEC07393.1
AF361601 mRNA Translation: AAK32769.1 Frameshift.
AY035052 mRNA Translation: AAK59557.1
AY051060 mRNA Translation: AAK93737.1
AY143880 mRNA Translation: AAN28819.1 Sequence problems.

Protein sequence database of the Protein Information Resource

More...PIRi		C84619

NCBI Reference Sequences

More...RefSeqi		NP_850034.1, NM_179703.2 [Q8RUW5-1]
NP_850035.1, NM_179704.1 [Q8RUW5-2]

Genome annotation databases

Ensembl plant genome annotation project

More...EnsemblPlantsi		AT2G22990.1; AT2G22990.1; AT2G22990 [Q8RUW5-1]
AT2G22990.3; AT2G22990.3; AT2G22990 [Q8RUW5-2]

Database of genes from NCBI RefSeq genomes

More...GeneIDi		816830

Gramene; a comparative resource for plants

More...Gramenei		AT2G22990.1; AT2G22990.1; AT2G22990 [Q8RUW5-1]
AT2G22990.3; AT2G22990.3; AT2G22990 [Q8RUW5-2]

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		ath:AT2G22990

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF275313 mRNA Translation: AAF78760.1
AC004401 Genomic DNA Translation: AAC17816.2 Sequence problems.
AC004786 Genomic DNA Translation: AAM15006.1 Sequence problems.
CP002685 Genomic DNA Translation: AEC07390.1
CP002685 Genomic DNA Translation: AEC07393.1
AF361601 mRNA Translation: AAK32769.1 Frameshift.
AY035052 mRNA Translation: AAK59557.1
AY051060 mRNA Translation: AAK93737.1
AY143880 mRNA Translation: AAN28819.1 Sequence problems.
PIRiC84619
RefSeqiNP_850034.1, NM_179703.2 [Q8RUW5-1]
NP_850035.1, NM_179704.1 [Q8RUW5-2]

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...PDBei

Protein Data Bank RCSB

More...RCSB PDBi

Protein Data Bank Japan

More...PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2DRFmodel-B20-433[»]
SMRiQ8RUW5
ModBaseiSearch...
PDBe-KBiSearch...

Protein-protein interaction databases

STRINGi3702.AT2G22990.3

Protein family/group databases

ESTHERiarath-SCP8, Carboxypeptidase_S10
MEROPSiS10.A14

Proteomic databases

PaxDbiQ8RUW5
PRIDEiQ8RUW5
ProteomicsDBi232855 [Q8RUW5-1]

Genome annotation databases

EnsemblPlantsiAT2G22990.1; AT2G22990.1; AT2G22990 [Q8RUW5-1]
AT2G22990.3; AT2G22990.3; AT2G22990 [Q8RUW5-2]
GeneIDi816830
GrameneiAT2G22990.1; AT2G22990.1; AT2G22990 [Q8RUW5-1]
AT2G22990.3; AT2G22990.3; AT2G22990 [Q8RUW5-2]
KEGGiath:AT2G22990

Organism-specific databases

AraportiAT2G22990
TAIRilocus:2045374, AT2G22990

Phylogenomic databases

eggNOGiKOG1282, Eukaryota
HOGENOMiCLU_008523_0_1_1
InParanoidiQ8RUW5
KOiK09757
OrthoDBi607679at2759
PhylomeDBiQ8RUW5

Enzyme and pathway databases

BioCyciARA:AT2G22990-MONOMER
BRENDAi2.3.1.92, 399

Miscellaneous databases

Protein Ontology

More...PROi		PR:Q8RUW5

Gene expression databases

ExpressionAtlasiQ8RUW5, baseline and differential
GenevisibleiQ8RUW5, AT

Family and domain databases

Gene3Di3.40.50.1820, 1 hit
InterProiView protein in InterPro
IPR029058, AB_hydrolase
IPR001563, Peptidase_S10
PANTHERiPTHR11802, PTHR11802, 1 hit
PfamiView protein in Pfam
PF00450, Peptidase_S10, 1 hit
PRINTSiPR00724, CRBOXYPTASEC
SUPFAMiSSF53474, SSF53474, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiSCP8_ARATH
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q8RUW5
Secondary accession number(s): O64809, Q3EBV9, Q9ASY4
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 6, 2007
Last sequence update: February 6, 2007
Last modified: August 12, 2020
This is version 119 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Direct protein sequencing, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. SIMILARITY comments
    Index of protein domains and families
  4. Peptidase families
    Classification of peptidase families and list of entries
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