Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 102 (17 Jun 2020)
Sequence version 1 (01 Jun 2002)
Previous versions | rss
Help videoAdd a publicationFeedback
Protein
Submitted name:

Calpain-like protein

Gene

dek1

Organism
Zea mays (Maize)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionHydrolase, Protease, Thiol proteaseSAAS annotation

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Calpain-like proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:dek1Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiZea mays (Maize)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri4577 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliopsidaLiliopsidaPoalesPoaceaePACMAD cladePanicoideaeAndropogonodaeAndropogoneaeTripsacinaeZea

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei6 – 34HelicalSequence analysisAdd BLAST29
Transmembranei65 – 90HelicalSequence analysisAdd BLAST26
Transmembranei96 – 119HelicalSequence analysisAdd BLAST24
Transmembranei131 – 152HelicalSequence analysisAdd BLAST22
Transmembranei164 – 186HelicalSequence analysisAdd BLAST23
Transmembranei238 – 258HelicalSequence analysisAdd BLAST21
Transmembranei264 – 282HelicalSequence analysisAdd BLAST19
Transmembranei294 – 315HelicalSequence analysisAdd BLAST22
Transmembranei321 – 341HelicalSequence analysisAdd BLAST21
Transmembranei624 – 644HelicalSequence analysisAdd BLAST21
Transmembranei664 – 684HelicalSequence analysisAdd BLAST21
Transmembranei696 – 714HelicalSequence analysisAdd BLAST19
Transmembranei720 – 742HelicalSequence analysisAdd BLAST23
Transmembranei771 – 791HelicalSequence analysisAdd BLAST21
Transmembranei820 – 846HelicalSequence analysisAdd BLAST27
Transmembranei853 – 874HelicalSequence analysisAdd BLAST22
Transmembranei886 – 909HelicalSequence analysisAdd BLAST24
Transmembranei921 – 941HelicalSequence analysisAdd BLAST21
Transmembranei947 – 970HelicalSequence analysisAdd BLAST24
Transmembranei982 – 1002HelicalSequence analysisAdd BLAST21
Transmembranei1014 – 1036HelicalSequence analysisAdd BLAST23
Transmembranei1057 – 1080HelicalSequence analysisAdd BLAST24

Keywords - Cellular componenti

Membrane

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q8RUQ1 baseline and differential

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini1703 – 2005Calpain catalyticInterPro annotationAdd BLAST303

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni365 – 408DisorderedSequence analysisAdd BLAST44

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi366 – 408PolarSequence analysisAdd BLAST43

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the peptidase C2 family.SAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG0045 Eukaryota
ENOG410XP0B LUCA

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00044 CysPc, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR022682 Calpain_domain_III
IPR022683 Calpain_III
IPR036213 Calpain_III_sf
IPR013320 ConA-like_dom_sf
IPR038765 Papain-like_cys_pep_sf
IPR000169 Pept_cys_AS
IPR001300 Peptidase_C2_calpain_cat

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF01067 Calpain_III, 1 hit
PF00648 Peptidase_C2, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00720 calpain_III, 1 hit
SM00230 CysPc, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF49758 SSF49758, 1 hit
SSF49899 SSF49899, 1 hit
SSF54001 SSF54001, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50203 CALPAIN_CAT, 1 hit
PS00139 THIOL_PROTEASE_CYS, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q8RUQ1-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MEGEGHHGVV LACSICGFLF AVLSPFSFWV LWAVNWRPWR LYSWIYARKW
60 70 80 90 100
PTYVQGPQLS TLCSLLTLCA WLVVISPIAV LLAWGSVLIA LLERNIIGLA
110 120 130 140 150
VIMTGVALLL SFYSIMLWWR TQWQSSKAVA YLLLLAVGLL CAYDFCAIYV
160 170 180 190 200
TAGASASELN SPSGFFFGVS VISLAINMLF ICKILFNVSG FDVDEYVRRS
210 220 230 240 250
YKFAYSDCVE VAPVSCSPEP PDPSELYMTK SSRVKHLGLL YISSLLVLVG
260 270 280 290 300
YSILYGLTSK EARWLGALTS VAVVILDWNL GLCSFRFELL KSRMIVLFVA
310 320 330 340 350
GTSRAFLVSF GVHYWYLGHC ISYAFVASVL LSAAVSSWLS ISNPSVARID
360 370 380 390 400
ALRSTVIKLR EGFRRKGQNS SSNSSEGCGS SVKRSSGSVE AGQNGNATDS
410 420 430 440 450
MYRSNSQSDG VNWSSIPFDR SNSCQEGRSS DKNIDSARAS LAHRSNSCLS
460 470 480 490 500
AVQDSETAVV SVDRHGDPTT SLVCSSSGLE SHGCEPSGSA TTSGNQQLLD
510 520 530 540 550
LNLAAIFQDR LNDPRISSML KKNGGLGDVE LANLLQDKGL DPNFSYMLKD
560 570 580 590 600
KVMDPRILAL LQRSSLDADR EHQDDVDVTA TDSDRLDTTI ANQISLSEEL
610 620 630 640 650
RRSGLEKWLN ISRLIFHHLA GSPIRAFIVF TVMFIIETAT VAIYRPETIK
660 670 680 690 700
VINATHEQFE FGFSILLLSP VVCSIMAFIW SLRAEEMLMT SKPQKYGFIA
710 720 730 740 750
WLLSTCVGLF LSFLSKSSVI LGLSLTVPLM VACLSFAVPI WIRNGYSFWI
760 770 780 790 800
PGREFANREN VSQAPGEKER ALFVITIAVF TASIIGLGAI VSAKPLDALG
810 820 830 840 850
YKGWDADKNS SYSPYATSMY LGWALSSTIA VITTGLIPIV AWFATYRFSP
860 870 880 890 900
SSAICVGLFA TVLVSFCGAS YWGVVNSRED GAPLKADFLA ALLPLLCIPA
910 920 930 940 950
FFSLFTGLYK WKDDDWKISR GVYLFVGMGM LLLFGAVAAV IVTIRPWTVG
960 970 980 990 1000
VACLVAILFL VFVIGVIHYW TSNNFYLTRT QMLLVCSIAF LLALAAFLMG
1010 1020 1030 1040 1050
LFHGKPFVGA SIGYFSFIFL LTGRALTVLL SPPIVVYSPR VLPVYVYDAH
1060 1070 1080 1090 1100
ADSAKNVSYA FLILYGIALA TEVWGVIASL IMNPPFVGAG VSATTLVIAF
1110 1120 1130 1140 1150
SFAVSRPCLT LKMMEDAVHF LSKDTVVQAM SRSANKTRNA ISGTYSAPQR
1160 1170 1180 1190 1200
SASSAALLVG DPALTLDRAG NFVLPRADVM KLRDRLRNEE IAAGSFLCGV
1210 1220 1230 1240 1250
KDCLLICPQS LSNIDYRRNM CAHARILALE EAIDTEWVYM WDKFGGYLLL
1260 1270 1280 1290 1300
LLGLTAKAEQ IQDEVRLRLF LDSIGLSDLS AKEIKKWMPE DRRQFELIQE
1310 1320 1330 1340 1350
SYIREKEMEE EALMQRREEE GKGRERRRAL LEREERKWKE LEISLLSSIP
1360 1370 1380 1390 1400
NTGSRDAAAM AAAVRAVGGD SALEDSFARD RVSSIANHIR KAQLARRAEQ
1410 1420 1430 1440 1450
TGIPGTICIL DDEPRSTGRH CGELDLCLCQ SQKVTLSIAV MVQPVSGPVC
1460 1470 1480 1490 1500
LFGSEFQKVC WEILVAGSEQ GMEAGQVGLR LVTKGERMTT VAKEWNIGAS
1510 1520 1530 1540 1550
SIADGRWHLV TVTLDADLGE ATSFIDGVYD GYQNGLPLPT DNGIWEPGTD
1560 1570 1580 1590 1600
IWVGARPPMD LDAFGRSDSE GSDSKMQIMD AFLWGRCLSE DEVTVLHTAM
1610 1620 1630 1640 1650
SPAEYGFFDL APGDAWHGSY SARVDDWESE EAYELYDQGD VEWDGQYSSG
1660 1670 1680 1690 1700
RKRPVHDAVA IDLDSFARRP RKPRFETRDE VNQRMLSVER AVRDALIAKG
1710 1720 1730 1740 1750
ERNFTDQEFP PEDRSLFVDP MNPPLKLQVV SEWMRPSDIA KEISISCQPC
1760 1770 1780 1790 1800
LFSGSVNSSD VCQGRLGDCW FLSAVAVLTE MSRISEVIIT PEYNDEGIYT
1810 1820 1830 1840 1850
VRFCIQGEWV AVVVDDWIPC ESPGKPAFAT SRKQNELWVS ILEKAYAKLH
1860 1870 1880 1890 1900
GSYEALEGGL VQDALVDLTG GAGEEIDMRS PQAQLDLASG RLWSQLLHFK
1910 1920 1930 1940 1950
QEGFLLGAGS PSGSDAHISS SGIVQGHAYS ILQVREVDGH KLIQIRNPWA
1960 1970 1980 1990 2000
NEVEWNGPWS DSSPEWTERM KHKLMHVPQS KNGVFWMSWQ DFQIHFRSIY
2010 2020 2030 2040 2050
VCRVYPPEMR YSVHGQWRGY NAGGCQDYDS WHQNPQYRLR VTGRDALYPV
2060 2070 2080 2090 2100
HVFITLTQGV GFSRKTNGFR NYQSSHDSSM FYIGMRILKT QGCRAAYNIY
2110 2120 2130 2140 2150
MHESAGGTDY VNSREISCEL VLDPYPKGYT IVPTTIHPGE EAPFVLSVFS

KASIRLEAV
Length:2,159
Mass (Da):238,987
Last modified:June 1, 2002 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i971C1A709BA5F5D4
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AY061804 Genomic DNA Translation: AAL38187.1
AY061805 mRNA Translation: AAL38188.1

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY061804 Genomic DNA Translation: AAL38187.1
AY061805 mRNA Translation: AAL38188.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Phylogenomic databases

eggNOGiKOG0045 Eukaryota
ENOG410XP0B LUCA

Gene expression databases

ExpressionAtlasiQ8RUQ1 baseline and differential

Family and domain databases

CDDicd00044 CysPc, 1 hit
InterProiView protein in InterPro
IPR022682 Calpain_domain_III
IPR022683 Calpain_III
IPR036213 Calpain_III_sf
IPR013320 ConA-like_dom_sf
IPR038765 Papain-like_cys_pep_sf
IPR000169 Pept_cys_AS
IPR001300 Peptidase_C2_calpain_cat
PfamiView protein in Pfam
PF01067 Calpain_III, 1 hit
PF00648 Peptidase_C2, 1 hit
SMARTiView protein in SMART
SM00720 calpain_III, 1 hit
SM00230 CysPc, 1 hit
SUPFAMiSSF49758 SSF49758, 1 hit
SSF49899 SSF49899, 1 hit
SSF54001 SSF54001, 1 hit
PROSITEiView protein in PROSITE
PS50203 CALPAIN_CAT, 1 hit
PS00139 THIOL_PROTEASE_CYS, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiQ8RUQ1_MAIZE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q8RUQ1
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: June 1, 2002
Last sequence update: June 1, 2002
Last modified: June 17, 2020
This is version 102 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again