UniProtKB - Q8REX0 (Q8REX0_FUSNN)
Protein
Submitted name:
D-3-phosphoglycerate dehydrogenase
Gene
FN0965
Organism
Fusobacterium nucleatum subsp. nucleatum (strain ATCC 25586 / DSM 15643 / BCRC 10681 / CIP 101130 / JCM 8532 / KCTC 2640 / LMG 13131 / VPI 4355)
Status
Functioni
GO - Molecular functioni
- NAD binding Source: InterPro
- phosphoglycerate dehydrogenase activity Source: UniProtKB-EC
Keywordsi
Molecular function | OxidoreductaseUniRule annotationImportedARBA annotation |
Enzyme and pathway databases
BioCyci | FNUC190304:G1FZS-1547-MONOMER |
Names & Taxonomyi
Protein namesi | |
Gene namesi | Ordered Locus Names:FN0965Imported |
Organismi | Fusobacterium nucleatum subsp. nucleatum (strain ATCC 25586 / DSM 15643 / BCRC 10681 / CIP 101130 / JCM 8532 / KCTC 2640 / LMG 13131 / VPI 4355)Imported |
Taxonomic identifieri | 190304 [NCBI] |
Taxonomic lineagei | Bacteria › Fusobacteria › Fusobacteriales › Fusobacteriaceae › Fusobacterium › |
Proteomesi |
|
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 30 – 313 | 2-Hacid_dhInterPro annotationAdd BLAST | 284 | |
Domaini | 111 – 289 | 2-Hacid_dh_CInterPro annotationAdd BLAST | 179 |
Coiled coil
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Coiled coili | 111 – 131 | Sequence analysisAdd BLAST | 21 |
Sequence similaritiesi
Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.UniRule annotation
Keywords - Domaini
Coiled coilSequence analysisPhylogenomic databases
eggNOGi | COG1052, Bacteria |
HOGENOMi | CLU_019796_1_3_0 |
InParanoidi | Q8REX0 |
OMAi | CALTDKI |
Family and domain databases
InterProi | View protein in InterPro IPR006139, D-isomer_2_OHA_DH_cat_dom IPR029753, D-isomer_DH_CS IPR006140, D-isomer_DH_NAD-bd IPR036291, NAD(P)-bd_dom_sf |
Pfami | View protein in Pfam PF00389, 2-Hacid_dh, 1 hit PF02826, 2-Hacid_dh_C, 1 hit |
SUPFAMi | SSF51735, SSF51735, 1 hit |
PROSITEi | View protein in PROSITE PS00670, D_2_HYDROXYACID_DH_2, 1 hit PS00671, D_2_HYDROXYACID_DH_3, 1 hit |
i Sequence
Sequence statusi: Complete.
Q8REX0-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MEKNKLKILF LDRNAVGPYE LKGIFSKYGE YTELNLTNND DIASYLKDYD
60 70 80 90 100
VVILNRIRLG KKEFEKTPHL KLVLLTGTGY NHIDLVAAKE YGVTIANVAN
110 120 130 140 150
YSTNSVSQLT MTLLLNELTR AEKLSQEVKQ NKWEEISNKM DRYYHVDTEG
160 170 180 190 200
KVLGILGHGN IGKKVESYAK SFGMEVMIAK IPGREYTDNL ENRFELDEVL
210 220 230 240 250
EKCDIFSIHA PLTDLTRDLI NLDRMKKMKK SAIILNLGRG PIINEEDLYY
260 270 280 290 300
VLKNKIISSA ATDVMTTEPP QNDCKLLELD NFTVTPHLAW KSLKSVERLF
310 320
AAIENNLNLF LENKLIGLES K
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AE009951 Genomic DNA Translation: AAL95161.1 |
RefSeqi | NP_603862.1, NC_003454.1 |
Genome annotation databases
EnsemblBacteriai | AAL95161; AAL95161; FN0965 |
GeneIDi | 991465 |
KEGGi | fnu:FN0965 |
PATRICi | fig|190304.8.peg.1530 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AE009951 Genomic DNA Translation: AAL95161.1 |
RefSeqi | NP_603862.1, NC_003454.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
STRINGi | 190304.FN0965 |
Genome annotation databases
EnsemblBacteriai | AAL95161; AAL95161; FN0965 |
GeneIDi | 991465 |
KEGGi | fnu:FN0965 |
PATRICi | fig|190304.8.peg.1530 |
Phylogenomic databases
eggNOGi | COG1052, Bacteria |
HOGENOMi | CLU_019796_1_3_0 |
InParanoidi | Q8REX0 |
OMAi | CALTDKI |
Enzyme and pathway databases
BioCyci | FNUC190304:G1FZS-1547-MONOMER |
Family and domain databases
InterProi | View protein in InterPro IPR006139, D-isomer_2_OHA_DH_cat_dom IPR029753, D-isomer_DH_CS IPR006140, D-isomer_DH_NAD-bd IPR036291, NAD(P)-bd_dom_sf |
Pfami | View protein in Pfam PF00389, 2-Hacid_dh, 1 hit PF02826, 2-Hacid_dh_C, 1 hit |
SUPFAMi | SSF51735, SSF51735, 1 hit |
PROSITEi | View protein in PROSITE PS00670, D_2_HYDROXYACID_DH_2, 1 hit PS00671, D_2_HYDROXYACID_DH_3, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | Q8REX0_FUSNN | |
Accessioni | Q8REX0Primary (citable) accession number: Q8REX0 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | June 1, 2002 |
Last sequence update: | June 1, 2002 | |
Last modified: | December 2, 2020 | |
This is version 106 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |