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Entry version 144 (08 May 2019)
Sequence version 3 (03 Nov 2009)
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Protein

RNA-binding protein 12

Gene

Rbm12

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionRNA-binding

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
RNA-binding protein 12
Alternative name(s):
RNA-binding motif protein 12
SH3/WW domain anchor protein in the nucleus
Short name:
SWAN
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Rbm12
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 2

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:1922960 Rbm12

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000817721 – 992RNA-binding protein 12Add BLAST992

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei352PhosphoserineBy similarity1
Modified residuei375PhosphoserineBy similarity1
Modified residuei420PhosphoserineBy similarity1
Modified residuei422PhosphoserineBy similarity1
Modified residuei424PhosphoserineBy similarity1
Modified residuei525PhosphoserineBy similarity1

Keywords - PTMi

Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q8R4X3

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q8R4X3

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q8R4X3

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q8R4X3

PeptideAtlas

More...
PeptideAtlasi
Q8R4X3

PRoteomics IDEntifications database

More...
PRIDEi
Q8R4X3

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q8R4X3

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q8R4X3

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000089824 Expressed in 269 organ(s), highest expression level in primitive streak

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q8R4X3 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q8R4X3 MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

Protein interaction database and analysis system

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IntActi
Q8R4X3, 2 interactors

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000050461

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

1992
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

Select the link destinations:

Protein Data Bank Europe

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PDBei

Protein Data Bank RCSB

More...
RCSB PDBi

Protein Data Bank Japan

More...
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2CQPNMR-A908-992[»]

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q8R4X3

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

Miscellaneous databases

Relative evolutionary importance of amino acids within a protein sequence

More...
EvolutionaryTracei
Q8R4X3

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini304 – 379RRM 1PROSITE-ProRule annotationAdd BLAST76
Domaini430 – 507RRM 2PROSITE-ProRule annotationAdd BLAST78
Domaini916 – 992RRM 3PROSITE-ProRule annotationAdd BLAST77

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi159 – 256Pro-richAdd BLAST98
Compositional biasi656 – 914Gly-richAdd BLAST259

Keywords - Domaini

Repeat

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG4307 Eukaryota
ENOG4111WZ9 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000160611

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q8R4X3

Identification of Orthologs from Complete Genome Data

More...
OMAi
VKLMAHC

Database of Orthologous Groups

More...
OrthoDBi
1067545at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q8R4X3

TreeFam database of animal gene trees

More...
TreeFami
TF331899

Family and domain databases

Conserved Domains Database

More...
CDDi
cd12745 RRM1_RBM12, 1 hit
cd12747 RRM2_RBM12, 1 hit
cd12512 RRM3_RBM12, 1 hit
cd12749 RRM4_RBM12, 1 hit
cd12751 RRM5_RBM12, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.30.70.330, 5 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR012677 Nucleotide-bd_a/b_plait_sf
IPR035979 RBD_domain_sf
IPR034591 RBM12_RRM1
IPR034594 RBM12_RRM2
IPR034855 RBM12_RRM3
IPR034856 RBM12_RRM4
IPR034854 RBM12_RRM5
IPR000504 RRM_dom

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00076 RRM_1, 3 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00360 RRM, 4 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF54928 SSF54928, 4 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50102 RRM, 3 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.Show allAlign All

Q8R4X3-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAVVIRLQGL PIVAGTMDIR HFFSGLTIPD GGVHIVGGEL GEAFIVFATD
60 70 80 90 100
EDARLGMMRT GGTIKGSKVT LLLSSKTEMQ NMIELSRRRF ETANLDIPPA
110 120 130 140 150
NASRSGPPPS SGMSSRVNLP AIVPNFNNPS PSVVTATTSV HESNKNIQTF
160 170 180 190 200
STASVGTAPP SMGTSFGSPT FSSTIPSTAS PMNTVPPPPI PPIPAMPSLP
210 220 230 240 250
PLPSIPPIPV PPPVPTLPPV PPVPPIPPVP SVPPMTTLPP MSGMPPLNPP
260 270 280 290 300
PVAPLPAGMN GSGAPIGLNN NMNPVFLGPL NPVNSIQMNS QSSVKSLPIN
310 320 330 340 350
PDDLYVSVHG MPFSAMENDV REFFHGLRVD AVHLLKDHVG RNNGNGLVKF
360 370 380 390 400
LSPQDTFEAL KRNRMLMIQR YVEVSPATER QWVAAGGHIT FKQSMGPSGQ
410 420 430 440 450
AHPPPQTLPR SKSPSGQKRS RSRSPHEAGF CVYLKGLPFE AENKHVIDFF
460 470 480 490 500
KKLDIVEDSI YIAYGPNGKA TGEGFVEFRN DADYKAALCR HKQYMGNRFI
510 520 530 540 550
QVHPITKKGM LEKIDMIRKR LQNFSYDQRE LVLNPEGEVS SAKVCAHITN
560 570 580 590 600
IPFSITKMDV LQFLEGIPVD ESAVHVLVDN NGQGLGQALV QFKTEDDAHK
610 620 630 640 650
SEHLHRKKLN GREAFVHIVT LEDMREIEKN PPAQGKKGLK ISVPGNPAVP
660 670 680 690 700
VIPSAGMPAA GIPTAGIPGA GLPSAGMPGA GMPSSGMPGP GMPGPGIPGA
710 720 730 740 750
GIPGPAMPGP AMPGPAMPGP AMPGPAMPGP AMPGPAMPGP AMPGPAIPGP
760 770 780 790 800
AIPGPAIPGA GIPSAGGEEH VFLTVGSKEA NNGPPFNFPG NFGGPNAFGP
810 820 830 840 850
PLPPPGLGGA FGDVRPVMPS VGNSGLPGLG LEVPGFGGAP NNISGPSGFG
860 870 880 890 900
GIPQNFGNGP GSLNAPPGFG SGPPGLGSVP GHLSGPPAFG PGPGPGPIHI
910 920 930 940 950
GGPPGFGASS GKPGPTIIKV QNMPFTVSID EILDFFYGYQ VIPGSVCLKY
960 970 980 990
NEKGMPTGEA MVAFESRDEA TAAVIDLNDR PIGSRKVKLV LG
Length:992
Mass (Da):102,796
Last modified:November 3, 2009 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i80FEBFDF17EE564F
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
B7ZCP9B7ZCP9_MOUSE
RNA-binding protein 12
Rbm12
288Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
B7ZCQ0B7ZCQ0_MOUSE
RNA-binding protein 12
Rbm12
143Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
B7ZCQ1B7ZCQ1_MOUSE
RNA-binding protein 12
Rbm12
133Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAH27810 differs from that shown. Reason: Erroneous initiation.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti122I → T in AAL83754 (Ref. 1) Curated1
Sequence conflicti122I → T in AAM73683 (Ref. 1) Curated1
Sequence conflicti122I → T in AAM73684 (Ref. 1) Curated1
Sequence conflicti122I → T in AAH26891 (PubMed:15489334).Curated1
Sequence conflicti572S → N in AAL83754 (Ref. 1) Curated1
Sequence conflicti572S → N in AAM73683 (Ref. 1) Curated1
Sequence conflicti572S → N in AAM73684 (Ref. 1) Curated1
Sequence conflicti572S → N in AAH26891 (PubMed:15489334).Curated1
Sequence conflicti719G → S in BAC28911 (PubMed:16141072).Curated1
Sequence conflicti729G → S in BAB30825 (PubMed:16141072).Curated1
Sequence conflicti739G → C in BAB30825 (PubMed:16141072).Curated1
Sequence conflicti756A → AIPGPA in BAC26338 (PubMed:16141072).Curated1
Sequence conflicti756A → AIPGPAIPGPT in AAL83754 (Ref. 1) Curated1
Sequence conflicti756A → AIPGPAIPGPT in AAM73683 (Ref. 1) Curated1
Sequence conflicti756A → AIPGPAIPGPT in AAM73684 (Ref. 1) Curated1
Sequence conflicti756A → AIPGPAIPGPT in AAH26891 (PubMed:15489334).Curated1
Sequence conflicti756A → AIPGPAIPGPT in AAH27810 (PubMed:15489334).Curated1
Sequence conflicti808G → GGG in AAL83754 (Ref. 1) Curated1
Sequence conflicti808G → GGG in AAM73683 (Ref. 1) Curated1
Sequence conflicti808G → GGG in AAM73684 (Ref. 1) Curated1
Sequence conflicti814V → A in AAL83754 (Ref. 1) Curated1
Sequence conflicti814V → A in AAM73683 (Ref. 1) Curated1
Sequence conflicti814V → A in AAM73684 (Ref. 1) Curated1
Sequence conflicti817V → G in AAL83754 (Ref. 1) Curated1
Sequence conflicti817V → G in AAM73683 (Ref. 1) Curated1
Sequence conflicti817V → G in AAM73684 (Ref. 1) Curated1
Sequence conflicti832E → D in AAL83754 (Ref. 1) Curated1
Sequence conflicti832E → D in AAM73683 (Ref. 1) Curated1
Sequence conflicti832E → D in AAM73684 (Ref. 1) Curated1
Sequence conflicti839 – 840AP → G in AAL83754 (Ref. 1) Curated2
Sequence conflicti839 – 840AP → G in AAM73683 (Ref. 1) Curated2
Sequence conflicti839 – 840AP → G in AAM73684 (Ref. 1) Curated2
Sequence conflicti897P → L in AAL83754 (Ref. 1) Curated1
Sequence conflicti897P → L in AAM73683 (Ref. 1) Curated1
Sequence conflicti897P → L in AAM73684 (Ref. 1) Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AF345334 mRNA Translation: AAL83754.1
AF393215 mRNA Translation: AAM73683.1
AF393216 mRNA Translation: AAM73684.1
AK017591 mRNA Translation: BAB30825.1
AK029180 mRNA Translation: BAC26338.1
AK035014 mRNA Translation: BAC28911.1
AK080772 mRNA Translation: BAC38017.1
AK166833 mRNA Translation: BAE39056.1
AL833786 Genomic DNA No translation available.
BC026891 mRNA Translation: AAH26891.2
BC027810 mRNA Translation: AAH27810.2 Different initiation.
BC052473 mRNA Translation: AAH52473.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS16961.1

NCBI Reference Sequences

More...
RefSeqi
NP_083673.3, NM_029397.3
NP_733486.2, NM_170598.2

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000059647; ENSMUSP00000050461; ENSMUSG00000089824
ENSMUST00000109604; ENSMUSP00000105233; ENSMUSG00000089824

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
75710

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mmu:75710

UCSC genome browser

More...
UCSCi
uc008nmh.1 mouse

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF345334 mRNA Translation: AAL83754.1
AF393215 mRNA Translation: AAM73683.1
AF393216 mRNA Translation: AAM73684.1
AK017591 mRNA Translation: BAB30825.1
AK029180 mRNA Translation: BAC26338.1
AK035014 mRNA Translation: BAC28911.1
AK080772 mRNA Translation: BAC38017.1
AK166833 mRNA Translation: BAE39056.1
AL833786 Genomic DNA No translation available.
BC026891 mRNA Translation: AAH26891.2
BC027810 mRNA Translation: AAH27810.2 Different initiation.
BC052473 mRNA Translation: AAH52473.1
CCDSiCCDS16961.1
RefSeqiNP_083673.3, NM_029397.3
NP_733486.2, NM_170598.2

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2CQPNMR-A908-992[»]
SMRiQ8R4X3
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiQ8R4X3, 2 interactors
STRINGi10090.ENSMUSP00000050461

PTM databases

iPTMnetiQ8R4X3
PhosphoSitePlusiQ8R4X3

Proteomic databases

EPDiQ8R4X3
jPOSTiQ8R4X3
MaxQBiQ8R4X3
PaxDbiQ8R4X3
PeptideAtlasiQ8R4X3
PRIDEiQ8R4X3

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000059647; ENSMUSP00000050461; ENSMUSG00000089824
ENSMUST00000109604; ENSMUSP00000105233; ENSMUSG00000089824
GeneIDi75710
KEGGimmu:75710
UCSCiuc008nmh.1 mouse

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
10137
MGIiMGI:1922960 Rbm12

Phylogenomic databases

eggNOGiKOG4307 Eukaryota
ENOG4111WZ9 LUCA
GeneTreeiENSGT00940000160611
InParanoidiQ8R4X3
OMAiVKLMAHC
OrthoDBi1067545at2759
PhylomeDBiQ8R4X3
TreeFamiTF331899

Miscellaneous databases

EvolutionaryTraceiQ8R4X3

Protein Ontology

More...
PROi
PR:Q8R4X3

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
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Gene expression databases

BgeeiENSMUSG00000089824 Expressed in 269 organ(s), highest expression level in primitive streak
ExpressionAtlasiQ8R4X3 baseline and differential
GenevisibleiQ8R4X3 MM

Family and domain databases

CDDicd12745 RRM1_RBM12, 1 hit
cd12747 RRM2_RBM12, 1 hit
cd12512 RRM3_RBM12, 1 hit
cd12749 RRM4_RBM12, 1 hit
cd12751 RRM5_RBM12, 1 hit
Gene3Di3.30.70.330, 5 hits
InterProiView protein in InterPro
IPR012677 Nucleotide-bd_a/b_plait_sf
IPR035979 RBD_domain_sf
IPR034591 RBM12_RRM1
IPR034594 RBM12_RRM2
IPR034855 RBM12_RRM3
IPR034856 RBM12_RRM4
IPR034854 RBM12_RRM5
IPR000504 RRM_dom
PfamiView protein in Pfam
PF00076 RRM_1, 3 hits
SMARTiView protein in SMART
SM00360 RRM, 4 hits
SUPFAMiSSF54928 SSF54928, 4 hits
PROSITEiView protein in PROSITE
PS50102 RRM, 3 hits

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiRBM12_MOUSE
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q8R4X3
Secondary accession number(s): B6ICZ5
, Q3TKT7, Q7TT14, Q8K373, Q8R302, Q9CS80
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 23, 2003
Last sequence update: November 3, 2009
Last modified: May 8, 2019
This is version 144 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
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