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Protein

Protein HID1

Gene

Hid1

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Recommended name:
Protein HID1
Alternative name(s):
HID1 domain-containing protein
Protein hid-1 homolog
Gene namesi
Name:Hid1
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 11

Organism-specific databases

MGIiMGI:2445087 Hid1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Golgi apparatus, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemovedBy similarity
ChainiPRO_00000792972 – 788Protein HID1Add BLAST787

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Lipidationi2N-myristoyl glycineBy similarity1
Modified residuei653PhosphoserineBy similarity1
Modified residuei670PhosphoserineCombined sources1

Keywords - PTMi

Lipoprotein, Myristate, Phosphoprotein

Proteomic databases

PaxDbiQ8R1F6
PRIDEiQ8R1F6

PTM databases

iPTMnetiQ8R1F6
PhosphoSitePlusiQ8R1F6

Expressioni

Gene expression databases

BgeeiENSMUSG00000034586 Expressed in 181 organ(s), highest expression level in lacrimal gland
CleanExiMM_C630004H02RIK
ExpressionAtlasiQ8R1F6 baseline and differential
GenevisibleiQ8R1F6 MM

Interactioni

Protein-protein interaction databases

BioGridi229885, 1 interactor
STRINGi10090.ENSMUSP00000102152

Structurei

3D structure databases

ProteinModelPortaliQ8R1F6
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the hid-1 family.Curated

Phylogenomic databases

eggNOGiKOG2226 Eukaryota
ENOG410XPB2 LUCA
GeneTreeiENSGT00390000003070
HOGENOMiHOG000231062
HOVERGENiHBG061276
InParanoidiQ8R1F6
OMAiFWKICDY
OrthoDBiEOG091G02BK
PhylomeDBiQ8R1F6
TreeFamiTF314291

Family and domain databases

InterProiView protein in InterPro
IPR026705 Hid-1/Ecm30
PANTHERiPTHR21575 PTHR21575, 1 hit
PfamiView protein in Pfam
PF12722 Hid1, 1 hit

Sequences (2+)i

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

This entry describes 2 isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 1 potential isoform that is computationally mapped.Show allAlign All

Isoform 1 (identifier: Q8R1F6-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MGSADSKLNF RKAVIQLTTK TQPVEATDNA FWDQFWADTA TSVQDVFALV
60 70 80 90 100
PAAEIRAVRE ESPSNLATLC YKAVEKLVQG AEGGCHSEKE KQVVLNCSRL
110 120 130 140 150
LTRVLPYIFE DPDWRGFFWS TVPGAGRGGQ GEEEDENARP LAESLLLAIA
160 170 180 190 200
DLLFCPDFTV QNHRRNDVDS AEDVHSLDSC EYIWEAGVGF AHSPQPNYIH
210 220 230 240 250
DMNRMELLKL LLTCFSEAMY LPPSPESGST NPWVQFFCST ENRHALPLFT
260 270 280 290 300
SLLNTVCAYD PVGYGIPYNH LLFSDYREPL VEEAAQVLIV TLDHDSATST
310 320 330 340 350
SPTVDGTTTG TAMDDADPPG PENLFVNYLS RIHREEDFQF ILKGIARLLS
360 370 380 390 400
NPLLQTYLPN STKKIQFHQE LLVLFWKLCD FNKKFLFFVL KSSDVLDILV
410 420 430 440 450
PILYFLNDAR ADQSRVGLMH IGVFILLLLS GERNFGVRLN KPYSVRVPMD
460 470 480 490 500
IPVFTGTHAD LLIVVFHKII TSGHQRLQPL FDCLLTIVVN VSPYLKSLSM
510 520 530 540 550
VTANKLLHLL EAFSTTWFLF SASQNHHLVF FLLEVFNNII QYQFDGNSNL
560 570 580 590 600
VYAIIRKRAV FHQLANLPTD PPSIHKALQR RRRTPEPLSR TGSQEGTSME
610 620 630 640 650
GSRPAAPAEP GTLKTSLVAT PGIDKLTEKS QVSEDGTLRS LEPESQQSSA
660 670 680 690 700
ENSPSDGESS QTWREQRRLS NASASGQWSP TSDWILSWKS KLPLQTIMRL
710 720 730 740 750
LQVLVPQVEK ICIDKGLTDE SEILRFLQHG TLVGLLPVPH PILIRKYQAN
760 770 780
SGTAMWFRTY MWGVIYLRNV DPPIWYDTDV KLFEIQRV
Length:788
Mass (Da):88,779
Last modified:June 1, 2002 - v1
Checksum:i1C9212C1CD7DDCAA
GO
Isoform 2 (identifier: Q8R1F6-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     130-130: Missing.

Note: No experimental confirmation available.
Show »
Length:787
Mass (Da):88,651
Checksum:i3384643CB93198A3
GO

Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
F6RGN1F6RGN1_MOUSE
Protein HID1
Hid1
273Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti332I → F in BAC31902 (PubMed:16141072).Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Alternative sequenceiVSP_014474130Missing in isoform 2. 1 Publication1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB087506 mRNA Translation: BAC67686.1
AK044395 mRNA Translation: BAC31902.1
AL603828 Genomic DNA No translation available.
BC024617 mRNA Translation: AAH24617.1
CCDSiCCDS25630.1 [Q8R1F6-1]
CCDS83927.1 [Q8R1F6-2]
RefSeqiNP_780663.1, NM_175454.2 [Q8R1F6-1]
UniGeneiMm.205707

Genome annotation databases

EnsembliENSMUST00000044152; ENSMUSP00000043789; ENSMUSG00000034586 [Q8R1F6-2]
ENSMUST00000106542; ENSMUSP00000102152; ENSMUSG00000034586 [Q8R1F6-1]
GeneIDi217310
KEGGimmu:217310
UCSCiuc007mhg.1 mouse [Q8R1F6-1]

Keywords - Coding sequence diversityi

Alternative splicing

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB087506 mRNA Translation: BAC67686.1
AK044395 mRNA Translation: BAC31902.1
AL603828 Genomic DNA No translation available.
BC024617 mRNA Translation: AAH24617.1
CCDSiCCDS25630.1 [Q8R1F6-1]
CCDS83927.1 [Q8R1F6-2]
RefSeqiNP_780663.1, NM_175454.2 [Q8R1F6-1]
UniGeneiMm.205707

3D structure databases

ProteinModelPortaliQ8R1F6
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi229885, 1 interactor
STRINGi10090.ENSMUSP00000102152

PTM databases

iPTMnetiQ8R1F6
PhosphoSitePlusiQ8R1F6

Proteomic databases

PaxDbiQ8R1F6
PRIDEiQ8R1F6

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000044152; ENSMUSP00000043789; ENSMUSG00000034586 [Q8R1F6-2]
ENSMUST00000106542; ENSMUSP00000102152; ENSMUSG00000034586 [Q8R1F6-1]
GeneIDi217310
KEGGimmu:217310
UCSCiuc007mhg.1 mouse [Q8R1F6-1]

Organism-specific databases

CTDi283987
MGIiMGI:2445087 Hid1

Phylogenomic databases

eggNOGiKOG2226 Eukaryota
ENOG410XPB2 LUCA
GeneTreeiENSGT00390000003070
HOGENOMiHOG000231062
HOVERGENiHBG061276
InParanoidiQ8R1F6
OMAiFWKICDY
OrthoDBiEOG091G02BK
PhylomeDBiQ8R1F6
TreeFamiTF314291

Miscellaneous databases

PROiPR:Q8R1F6
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000034586 Expressed in 181 organ(s), highest expression level in lacrimal gland
CleanExiMM_C630004H02RIK
ExpressionAtlasiQ8R1F6 baseline and differential
GenevisibleiQ8R1F6 MM

Family and domain databases

InterProiView protein in InterPro
IPR026705 Hid-1/Ecm30
PANTHERiPTHR21575 PTHR21575, 1 hit
PfamiView protein in Pfam
PF12722 Hid1, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiHID1_MOUSE
AccessioniPrimary (citable) accession number: Q8R1F6
Secondary accession number(s): A2A6S8, Q8C8V6
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 5, 2005
Last sequence update: June 1, 2002
Last modified: September 12, 2018
This is version 114 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
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