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Protein

Histone H2A

Gene

H2afv

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionDNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Histone H2AUniRule annotation
Gene namesi
Name:H2afvImported
ORF Names:mCG_121516Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 11

Organism-specific databases

MGIiMGI:1924855 H2afv

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Chromosome, Nucleosome coreUniRule annotation, NucleusUniRule annotation

Expressioni

Gene expression databases

BgeeiENSMUSG00000041126

Interactioni

Subunit structurei

The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.UniRule annotation

GO - Molecular functioni

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini57 – 89Histone_H2A_CInterPro annotationAdd BLAST33

Sequence similaritiesi

Belongs to the histone H2A family.UniRule annotationSAAS annotation

Phylogenomic databases

GeneTreeiENSGT00900000140979
HOGENOMiHOG000234652
HOVERGENiHBG009342

Family and domain databases

Gene3Di1.10.20.10, 1 hit
InterProiView protein in InterPro
IPR009072 Histone-fold
IPR002119 Histone_H2A
IPR032454 Histone_H2A_C
PfamiView protein in Pfam
PF16211 Histone_H2A_C, 1 hit
PRINTSiPR00620 HISTONEH2A
SMARTiView protein in SMART
SM00414 H2A, 1 hit
SUPFAMiSSF47113 SSF47113, 1 hit

Sequencei

Sequence statusi: Complete.

Q8R029-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAGGKAGKDS GKAKAKAVSR SQRAGLQVLE LAGNASKDLK VKRITPRHLQ
60 70 80 90
LAIRGDEELD SLIKATIAGG GVIPHIHKSL IGKKGQQKTA
Length:90
Mass (Da):9,375
Last modified:June 1, 2002 - v1
Checksum:i34DA01283B7A93F1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL646020 Genomic DNA No translation available.
BC028539 mRNA Translation: AAH28539.1
CH466574 Genomic DNA Translation: EDL40595.1
RefSeqiNP_001333993.1, NM_001347064.1
UniGeneiMm.27624

Genome annotation databases

EnsembliENSMUST00000093346; ENSMUSP00000091037; ENSMUSG00000041126
GeneIDi77605
UCSCiuc007hyq.2 mouse

Similar proteinsi

Entry informationi

Entry nameiQ8R029_MOUSE
AccessioniPrimary (citable) accession number: Q8R029
Secondary accession number(s): Q5NC91
Entry historyiIntegrated into UniProtKB/TrEMBL: June 1, 2002
Last sequence update: June 1, 2002
Last modified: March 28, 2018
This is version 113 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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