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UniProtKB - Q8QTG5 (Q8QTG5_WSSV)

Entry version 87 (19 Jan 2022)
Sequence version 1 (01 Jun 2002)
Previous versions | rss
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Protein

DNA-directed DNA polymerase

Gene
N/A
Organism
White spot syndrome virus (WSSV) (White spot bacilliform virus)
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDNA-directed DNA polymeraseARBA annotation, Nucleotidyltransferase, Transferase
Biological processDNA replication, Viral DNA replicationARBA annotation

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
DNA-directed DNA polymeraseARBA annotation (EC:2.7.7.7ARBA annotation)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiWhite spot syndrome virus (WSSV) (White spot bacilliform virus)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri92652 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiViruses › Naldaviricetes › Nimaviridae › Whispovirus ›
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section only exists in viral entries and indicates the host(s) either as a specific organism or taxonomic group of organisms that are susceptible to be infected by a virus.<p><a href='/help/virus_host' target='_top'>More...</a></p>Virus hostiCrustacea [TaxID: 6657]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000281246 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Genome

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini665 – 803DNA_pol_B_exo1InterPro annotationAdd BLAST139

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1950 – 2025DisorderedSequence analysisAdd BLAST76

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili1257 – 1277Sequence analysisAdd BLAST21
Coiled coili2087 – 2107Sequence analysisAdd BLAST21

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi1953 – 1975Acidic residuesSequence analysisAdd BLAST23
Compositional biasi1976 – 2018Basic and acidic residuesSequence analysisAdd BLAST43

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the DNA polymerase type-B family.ARBA annotation

Keywords - Domaini

Coiled coilSequence analysis

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		3.30.420.10, 1 hit
3.90.1600.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR006172, DNA-dir_DNA_pol_B
IPR017964, DNA-dir_DNA_pol_B_CS
IPR006133, DNA-dir_DNA_pol_B_exonuc
IPR043502, DNA/RNA_pol_sf
IPR023211, DNA_pol_palm_dom_sf
IPR012337, RNaseH-like_sf
IPR036397, RNaseH_sf

Pfam protein domain database

More...Pfami		View protein in Pfam
PF03104, DNA_pol_B_exo1, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00486, POLBc, 1 hit

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF53098, SSF53098, 1 hit
SSF56672, SSF56672, 1 hit

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS00116, DNA_POLYMERASE_B, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q8QTG5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MTSPAPSPSS TPKSSCTTIV NRCGFLLDNN KEVVIYDTNS KFKCEPKNLE 
        60         70         80         90        100
LIGVLSGVSD NVVTQISPDQ IFVGTYMVKY NWSKSGHERF SDMSNNCLDN 
       110        120        130        140        150
ITRPSEVIES VIKKTSSDFK MKYTRSLMDH TEKYYFSGDQ KLSKISSWCT 
       160        170        180        190        200
TPITTVGMQL RLENFVKEEH ETVVVHNPSG MTGFNIFNSS PVYFEVHNEM 
       210        220        230        240        250
DALIFMAAFL KHNSLWGEIN ANMDLYTFDY AGAFLDERWC HHEKSFSVVR 
       260        270        280        290        300
AQLINSYYKC RRKIMQALDN NYNNKNKKRK NVGGAPAFTF MSGDGEGGKE 
       310        320        330        340        350
ALEASFDVIG GTRGGRFGVD STPCPHSSAM QLKLDNEGNY GCIACFASMF 
       360        370        380        390        400
FVLENPGDES SFISTDASKI GQAQAWIDER LRNNENGGEE NNVFKKTFHM 
       410        420        430        440        450
LADITQKAHE TAYSNTIPLG PNGRQWNWPT HTVEPIAHEF VTHSLVNTLK 
       460        470        480        490        500
NLGDRKLPRF NFDILYNLLN PFGKMLLVFI QNCHILTGHK NNENVVPRGS 
       510        520        530        540        550
ASGKWWTINF VGVNMWTFQV TKCKVEKDRK ISDLACMETL PRLPNPGSTT 
       560        570        580        590        600
VDDRIVFKGF CRGENLGSVG EVVSDITQSV KNFCLMVENR KFSVDKETGF 
       610        620        630        640        650
ISSESIVSDP FFSLEVTGCR SNRAQDTINN GRVSARVMRI LKSREGARVW 
       660        670        680        690        700
LAKDENAIIF ENVNHDTAIS TDAMERAIGQ HKILYYDIET TDKDFTDKKS 
       710        720        730        740        750
VITSIGFCLC TGGDMTHGGE RGVFGLVAPG SDVEKVKETI INSYDPEEKE 
       760        770        780        790        800
DIMKQCPQVI EIFTNEFEML LGFGKYIDKV KPHVISGWNN VAFDDPFVFT 
       810        820        830        840        850
RIVKHLSDHT KDMSYCVADA STAESVLPRA TEGGGGETPY RLSTPQERIQ 
       860        870        880        890        900
LASTGIFNKL GKFVDKKTGM LKPEMTADLL AGAESQANTK FKERNKLSSS 
       910        920        930        940        950
NKGSAGWFQK IIGGMCSAIR LDLMKVCEKA YKESLSEFNL NAVLAKVSSV 
       960        970        980        990       1000
GDKVKNVKDE VDLHFHLLGF LKLKKAQDQA KVHVYCCKDA YLTGIVSTSI 
      1010       1020       1030       1040       1050
NKEGEIFRLC MDSALTEAVV TANLATPLCI GEGAICRNMG EERADRRGVG 
      1060       1070       1080       1090       1100
VRRHSIATDT KGGMVSQPIV NHVPYQTIDM TSLYPMTMCQ NNLCTTTFVT 
      1110       1120       1130       1140       1150
HRQIMQLRDR LVLEKMKNKT TDSLLLLDVI DECNQIVLSE YRPIDIAVAS 
      1160       1170       1180       1190       1200
WKNSNSNRQT PITRIEESLG LRFIENLDAE KTNNKTWCTN TSPNMNVTAA 
      1210       1220       1230       1240       1250
GMDYFPEIVC DINMQFAAKV NDDMHIAPAS LEYMLQVLPI MLIDRPYIGA 
      1260       1270       1280       1290       1300
HITAGKCRTL EDILSELEKD FSVEKDEEII RTHWTFKGQK QYDFCHSPVT 
      1310       1320       1330       1340       1350
QMARHIIEST GRNIRDYEGN EKFERLVSLS DRIYRRVGAF DSANDPAVRL 
      1360       1370       1380       1390       1400
WSSRLINVGM LVRTWNVKTD ILKGIIPQMQ ATYRAGRVVM QNKAKEFAKM 
      1410       1420       1430       1440       1450
GDMKRAGLNK VGQNIMKLGM NSMYGHLALR ARSSRKEFAS GSANTASSIS 
      1460       1470       1480       1490       1500
NMSATGGIGG GTRHSVTANQ ITENARCVFG NIGCGLQMAL PGTKQTYGDT 
      1510       1520       1530       1540       1550
DSVFCVHNIV GDGGMIPEYD EQTGKYYYVM DIALKNKMAA IIPILVNSLT 
      1560       1570       1580       1590       1600
KGIQFVERRD AGVGMMNIAH ERLAVAGLLF AKKTYHMLHF NENSAAFNDM 
      1610       1620       1630       1640       1650
IKLKSTDNNN KFASFIKRPS HADGYVVPHN PSLILRAAEG PAGKKLKSFL 
      1660       1670       1680       1690       1700
EEEGIHDEKS MEEWFTSSPT WMAMDASVIS NLYASQIVGV EKGNWIDAMT 
      1710       1720       1730       1740       1750
SRPIEAGTEM MEAVTQANAA FTPYKKGAFV KKGITPTTKL KGLQSLIARF 
      1760       1770       1780       1790       1800
LPKIEEKKSC YLDVMKNHVE NFASHITNPA MMITSSRVNK FDTSKEQSRP 
      1810       1820       1830       1840       1850
NPLALAINNH LNPSSEISLG QKFKTVTSVS SWSLSAEEGE VPAGYFNAGS 
      1860       1870       1880       1890       1900
VRWDATNMKG SVPAFSVKNL SVVPNAITSV YKMVESDKTA IKSMIAKNVE 
      1910       1920       1930       1940       1950
VLCSTSANTG FSLRRGALSF NTGVIVTKDV AMACIRSLNN KQMLLFVGGG 
      1960       1970       1980       1990       2000
KDYGEDDDDD DEEAEEEDEE NGENEENKGD CVTEKKIPGR STNKDVGEET 
      2010       2020       2030       2040       2050
KTSEKTEGER KGSKTAKGKT EEIASSLSKC GKKDARDVIL DRLLKATHSS 
      2060       2070       2080       2090       2100
CTNNEERTRV LQQYSNCTLS SYITSVMKLD QRVADQMENL ISQLDQIRNL 
      2110       2120       2130       2140       2150
SNKKRQEKGG PFKSELDAMV AAVKVKFFPV LDASRKLTQD HWKKCPVSIP 
      2160       2170       2180       2190       2200
ETREEKPLMG VPFEVALNSL IGKHKCTDTC DMACCQSLYF VLLYTLALKF 
      2210       2220       2230       2240       2250
ENERLARQIG LDDSVDLMAE MLFGGDKLLA QEVLKRVKDA QDRKLVKSLL 
      2260       2270       2280       2290       2300
PLNYNHDTNT IIFLFESLRF AQKPVAGMSV SEIKDAVRGL AFSTTTGTVW 
      2310       2320       2330       2340       2350
NYTDERFFGP LYNMDELCNE RVNGNCKLSF ITGIYHTAAV ELAAACLSCV 

L
Length:2,351
Mass (Da):261,884
Last modified:June 1, 2002 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i4BC38F31C1210979
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AF440570 Genomic DNA Translation: AAL88907.1

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF440570 Genomic DNA Translation: AAL88907.1

3D structure databases

Database of comparative protein structure models

More...ModBasei		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

Family and domain databases

Gene3Di3.30.420.10, 1 hit
3.90.1600.10, 1 hit
InterProiView protein in InterPro
IPR006172, DNA-dir_DNA_pol_B
IPR017964, DNA-dir_DNA_pol_B_CS
IPR006133, DNA-dir_DNA_pol_B_exonuc
IPR043502, DNA/RNA_pol_sf
IPR023211, DNA_pol_palm_dom_sf
IPR012337, RNaseH-like_sf
IPR036397, RNaseH_sf
PfamiView protein in Pfam
PF03104, DNA_pol_B_exo1, 1 hit
SMARTiView protein in SMART
SM00486, POLBc, 1 hit
SUPFAMiSSF53098, SSF53098, 1 hit
SSF56672, SSF56672, 1 hit
PROSITEiView protein in PROSITE
PS00116, DNA_POLYMERASE_B, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiQ8QTG5_WSSV
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q8QTG5
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: June 1, 2002
Last sequence update: June 1, 2002
Last modified: January 19, 2022
This is version 87 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
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