Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Arginine--tRNA ligase

Gene

argS

Organism
Methanosarcina mazei (strain ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM 11833 / OCM 88) (Methanosarcina frisia)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminoacyl-tRNA synthetase, Ligase
Biological processProtein biosynthesis
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Arginine--tRNA ligaseUniRule annotation (EC:6.1.1.19UniRule annotation)
Alternative name(s):
Arginyl-tRNA synthetaseUniRule annotation
Short name:
ArgRSUniRule annotation
Gene namesi
Name:argSUniRule annotation
Ordered Locus Names:MM_1348
OrganismiMethanosarcina mazei (strain ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM 11833 / OCM 88) (Methanosarcina frisia)
Taxonomic identifieri192952 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaMethanomicrobiaMethanosarcinalesMethanosarcinaceaeMethanosarcina
Proteomesi
  • UP000000595 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001516481 – 569Arginine--tRNA ligaseAdd BLAST569

Proteomic databases

PRIDEiQ8PX74

Interactioni

Protein-protein interaction databases

STRINGi192952.MM_1348

Structurei

3D structure databases

ProteinModelPortaliQ8PX74
SMRiQ8PX74
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi123 – 133"HIGH" regionAdd BLAST11

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

eggNOGiarCOG00487 Archaea
COG0018 LUCA
HOGENOMiHOG000247213
KOiK01887
OMAiNKPLHLG
OrthoDBiPOG093Z013U

Family and domain databases

CDDicd00671 ArgRS_core, 1 hit
Gene3Di3.30.1360.70, 1 hit
3.40.50.620, 1 hit
HAMAPiMF_00123 Arg_tRNA_synth, 1 hit
InterProiView protein in InterPro
IPR001412 aa-tRNA-synth_I_CS
IPR001278 Arg-tRNA-ligase
IPR005148 Arg-tRNA-synth_N
IPR036695 Arg-tRNA-synth_N_sf
IPR035684 ArgRS_core
IPR008909 DALR_anticod-bd
IPR014729 Rossmann-like_a/b/a_fold
IPR009080 tRNAsynth_Ia_anticodon-bd
PANTHERiPTHR11956 PTHR11956, 1 hit
PfamiView protein in Pfam
PF03485 Arg_tRNA_synt_N, 1 hit
PF05746 DALR_1, 1 hit
PF00750 tRNA-synt_1d, 1 hit
PRINTSiPR01038 TRNASYNTHARG
SMARTiView protein in SMART
SM01016 Arg_tRNA_synt_N, 1 hit
SM00836 DALR_1, 1 hit
SUPFAMiSSF47323 SSF47323, 1 hit
SSF55190 SSF55190, 1 hit
TIGRFAMsiTIGR00456 argS, 1 hit
PROSITEiView protein in PROSITE
PS00178 AA_TRNA_LIGASE_I, 1 hit

Sequencei

Sequence statusi: Complete.

Q8PX74-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MFLELKAQAT SILKEAIRKA GFEVEDSELQ FETSPHADLA SRAAFRLAGI
60 70 80 90 100
HRQNPKDLAS RIVSAVEIPE GSFIGKVSAA GPYINFFAGK HYLNGTVNAV
110 120 130 140 150
LKEKEKFGCG APKDRILLEH TSANPNGPLH VGHIRNSIIG DTLARILRRA
160 170 180 190 200
GYDVEVQYYV NDMGRQIAVV SWACERFELD LSRKSDSAIA DVYIKANVEL
210 220 230 240 250
DKNPGYIKEI DALMEKVEAG DVRTIEHFDK AVSLAVAGIK ETLLRLNVAH
260 270 280 290 300
DKFVSESTFL KSGAVHDIVE RIKATGRTKT DKGALVVDLS DYGFEKTLVI
310 320 330 340 350
QRSNGTSLYT TRDLAYHEWK AGQADRIIDV FGADHKLISG QLRATLNAIG
360 370 380 390 400
VKEPEVVIFE FVSLPEGSMS TRRGQFISAD DLFDRVTGAA FEQVETRRPE
410 420 430 440 450
TSYEFKKQVA EAVGLGAVRY DIVRVSPEKS TVFNWKEALD FEKQGAPYIQ
460 470 480 490 500
YSHARACSIL EKAKEEAAWN PDKEIDPSLL VEDSEIDLIK KMAMFDSVID
510 520 530 540 550
LGARELKPHV LAIYARELAD AFNQFYRFVP VIAAEDENVR AARLALVDCA
560
RVVLANSLDT LGIIAPESM
Length:569
Mass (Da):63,055
Last modified:October 10, 2002 - v1
Checksum:iD7D56C7A9800FB86
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE008384 Genomic DNA Translation: AAM31044.1
RefSeqiWP_011033294.1, NC_003901.1

Genome annotation databases

EnsemblBacteriaiAAM31044; AAM31044; MM_1348
GeneIDi24879662
KEGGimma:MM_1348
PATRICifig|192952.21.peg.1562

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE008384 Genomic DNA Translation: AAM31044.1
RefSeqiWP_011033294.1, NC_003901.1

3D structure databases

ProteinModelPortaliQ8PX74
SMRiQ8PX74
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi192952.MM_1348

Proteomic databases

PRIDEiQ8PX74

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAM31044; AAM31044; MM_1348
GeneIDi24879662
KEGGimma:MM_1348
PATRICifig|192952.21.peg.1562

Phylogenomic databases

eggNOGiarCOG00487 Archaea
COG0018 LUCA
HOGENOMiHOG000247213
KOiK01887
OMAiNKPLHLG
OrthoDBiPOG093Z013U

Family and domain databases

CDDicd00671 ArgRS_core, 1 hit
Gene3Di3.30.1360.70, 1 hit
3.40.50.620, 1 hit
HAMAPiMF_00123 Arg_tRNA_synth, 1 hit
InterProiView protein in InterPro
IPR001412 aa-tRNA-synth_I_CS
IPR001278 Arg-tRNA-ligase
IPR005148 Arg-tRNA-synth_N
IPR036695 Arg-tRNA-synth_N_sf
IPR035684 ArgRS_core
IPR008909 DALR_anticod-bd
IPR014729 Rossmann-like_a/b/a_fold
IPR009080 tRNAsynth_Ia_anticodon-bd
PANTHERiPTHR11956 PTHR11956, 1 hit
PfamiView protein in Pfam
PF03485 Arg_tRNA_synt_N, 1 hit
PF05746 DALR_1, 1 hit
PF00750 tRNA-synt_1d, 1 hit
PRINTSiPR01038 TRNASYNTHARG
SMARTiView protein in SMART
SM01016 Arg_tRNA_synt_N, 1 hit
SM00836 DALR_1, 1 hit
SUPFAMiSSF47323 SSF47323, 1 hit
SSF55190 SSF55190, 1 hit
TIGRFAMsiTIGR00456 argS, 1 hit
PROSITEiView protein in PROSITE
PS00178 AA_TRNA_LIGASE_I, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiSYR_METMA
AccessioniPrimary (citable) accession number: Q8PX74
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 10, 2002
Last sequence update: October 10, 2002
Last modified: September 12, 2018
This is version 104 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again