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Protein

Ribonuclease H

Gene

rnhA

Organism
Xanthomonas axonopodis pv. citri (strain 306)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.UniRule annotation

Catalytic activityi

Endonucleolytic cleavage to 5'-phosphomonoester.UniRule annotation

Cofactori

Mg2+UniRule annotationNote: Binds 1 Mg2+ ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi9Magnesium 1UniRule annotation1
Metal bindingi9Magnesium 2UniRule annotation1
Metal bindingi47Magnesium 1UniRule annotation1
Metal bindingi69Magnesium 1UniRule annotation1
Metal bindingi133Magnesium 2UniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionEndonuclease, Hydrolase, Nuclease
LigandMagnesium, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Ribonuclease HUniRule annotation (EC:3.1.26.4UniRule annotation)
Short name:
RNase HUniRule annotation
Gene namesi
Name:rnhAUniRule annotation
Ordered Locus Names:XAC1089
OrganismiXanthomonas axonopodis pv. citri (strain 306)
Taxonomic identifieri190486 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaXanthomonadalesXanthomonadaceaeXanthomonas
Proteomesi
  • UP000000576 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001954221 – 150Ribonuclease HAdd BLAST150

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi190486.XAC1089

Structurei

3D structure databases

ProteinModelPortaliQ8PNH8
SMRiQ8PNH8
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 141RNase HUniRule annotationAdd BLAST141

Sequence similaritiesi

Belongs to the RNase H family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4108UMW Bacteria
COG0328 LUCA
HOGENOMiHOG000040465
KOiK03469
OMAiMQEIEIF
OrthoDBiPOG091H04XT

Family and domain databases

CDDicd09278 RNase_HI_prokaryote_like, 1 hit
Gene3Di3.30.420.10, 1 hit
HAMAPiMF_00042 RNase_H, 1 hit
InterProiView protein in InterPro
IPR012337 RNaseH-like_sf
IPR002156 RNaseH_domain
IPR036397 RNaseH_sf
IPR022892 RNaseHI
PfamiView protein in Pfam
PF00075 RNase_H, 1 hit
SUPFAMiSSF53098 SSF53098, 1 hit
PROSITEiView protein in PROSITE
PS50879 RNASE_H, 1 hit

Sequencei

Sequence statusi: Complete.

Q8PNH8-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MKSIEVHTDG SCLGNPGPGG WAALLRYNGR EKELAGGEAV STNNRMELMA
60 70 80 90 100
AIMALETLTE PCQIVLHTDS QYVRQGITEW MPGWVRRNWK TAGCDPVKNR
110 120 130 140 150
ELWERLHAAT QRHRIDWRWV KGHNGDPDNE RVDVLARNQA IAQRGGLATS
Length:150
Mass (Da):16,856
Last modified:October 1, 2002 - v1
Checksum:i1DED947AD1EDE5F0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE008923 Genomic DNA Translation: AAM35964.1
RefSeqiWP_011050697.1, NC_003919.1

Genome annotation databases

EnsemblBacteriaiAAM35964; AAM35964; XAC1089
KEGGixac:XAC1089

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE008923 Genomic DNA Translation: AAM35964.1
RefSeqiWP_011050697.1, NC_003919.1

3D structure databases

ProteinModelPortaliQ8PNH8
SMRiQ8PNH8
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi190486.XAC1089

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAM35964; AAM35964; XAC1089
KEGGixac:XAC1089

Phylogenomic databases

eggNOGiENOG4108UMW Bacteria
COG0328 LUCA
HOGENOMiHOG000040465
KOiK03469
OMAiMQEIEIF
OrthoDBiPOG091H04XT

Family and domain databases

CDDicd09278 RNase_HI_prokaryote_like, 1 hit
Gene3Di3.30.420.10, 1 hit
HAMAPiMF_00042 RNase_H, 1 hit
InterProiView protein in InterPro
IPR012337 RNaseH-like_sf
IPR002156 RNaseH_domain
IPR036397 RNaseH_sf
IPR022892 RNaseHI
PfamiView protein in Pfam
PF00075 RNase_H, 1 hit
SUPFAMiSSF53098 SSF53098, 1 hit
PROSITEiView protein in PROSITE
PS50879 RNASE_H, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiRNH_XANAC
AccessioniPrimary (citable) accession number: Q8PNH8
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 8, 2002
Last sequence update: October 1, 2002
Last modified: October 10, 2018
This is version 94 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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