Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Glutamine--fructose-6-phosphate aminotransferase [isomerizing]

Gene

glmS

Organism
Xanthomonas axonopodis pv. citri (strain 306)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.UniRule annotation

Catalytic activityi

L-glutamine + D-fructose 6-phosphate = L-glutamate + D-glucosamine 6-phosphate.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei2Nucleophile; for GATase activityUniRule annotation1
Active sitei604For Fru-6P isomerization activityUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminotransferase, Transferase

Enzyme and pathway databases

BioCyciXAXO190486:XAC_RS18390-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamine--fructose-6-phosphate aminotransferase [isomerizing]UniRule annotation (EC:2.6.1.16UniRule annotation)
Alternative name(s):
D-fructose-6-phosphate amidotransferaseUniRule annotation
GFATUniRule annotation
Glucosamine-6-phosphate synthaseUniRule annotation
Hexosephosphate aminotransferaseUniRule annotation
L-glutamine--D-fructose-6-phosphate amidotransferaseUniRule annotation
Gene namesi
Name:glmSUniRule annotation
Ordered Locus Names:XAC3637
OrganismiXanthomonas axonopodis pv. citri (strain 306)
Taxonomic identifieri190486 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaXanthomonadalesXanthomonadaceaeXanthomonas
Proteomesi
  • UP000000576 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemovedUniRule annotation
ChainiPRO_00001354142 – 609Glutamine--fructose-6-phosphate aminotransferase [isomerizing]Add BLAST608

Interactioni

Subunit structurei

Homodimer.UniRule annotation

Protein-protein interaction databases

STRINGi190486.XAC3637

Structurei

3D structure databases

ProteinModelPortaliQ8PGH9
SMRiQ8PGH9
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini2 – 217Glutamine amidotransferase type-2UniRule annotationAdd BLAST216
Domaini285 – 425SIS 1UniRule annotationAdd BLAST141
Domaini458 – 599SIS 2UniRule annotationAdd BLAST142

Keywords - Domaini

Glutamine amidotransferase, Repeat

Phylogenomic databases

eggNOGiENOG4105C46 Bacteria
COG0449 LUCA
HOGENOMiHOG000258896
KOiK00820
OMAiGTSHYAG
OrthoDBiPOG091H0061

Family and domain databases

CDDicd05008 SIS_GlmS_GlmD_1, 1 hit
cd05009 SIS_GlmS_GlmD_2, 1 hit
Gene3Di3.60.20.10, 1 hit
HAMAPiMF_00164 GlmS, 1 hit
InterProiView protein in InterPro
IPR017932 GATase_2_dom
IPR035466 GlmS/AgaS_SIS
IPR035490 GlmS/FrlB_SIS
IPR005855 GlmS_trans
IPR029055 Ntn_hydrolases_N
IPR001347 SIS
PANTHERiPTHR10937:SF0 PTHR10937:SF0, 1 hit
PfamiView protein in Pfam
PF01380 SIS, 2 hits
SUPFAMiSSF56235 SSF56235, 1 hit
TIGRFAMsiTIGR01135 glmS, 1 hit
PROSITEiView protein in PROSITE
PS51278 GATASE_TYPE_2, 1 hit
PS51464 SIS, 2 hits

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q8PGH9-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MCGIVGAIAG RDVVPVLIEG LKRLEYRGYD SSGIAVLDGA QVRRVRRTGR
60 70 80 90 100
VAEMAQAAQA EQLGATLGIG HTRWATHGGV TEANAHPHIS AGVALVHNGI
110 120 130 140 150
IENHEAQREK LRALGYTFES QTDTEVIAHL IHHHLGSAGD LLTALQHTVK
160 170 180 190 200
ELTGAYALAV VSQAEPERFV CARMGCPLLI GVGEGENFVA SDVSAIVQAT
210 220 230 240 250
RQVIFLEEGD TAELRRDGVR IFDGNDAPVE RPLHLSDVSL ASLELGPFRH
260 270 280 290 300
FMQKEIHEQP RALADTIEAA IDAKGFPASL FGANAEAVLR DIEGVQILAC
310 320 330 340 350
GTSYYAGMTA RYWIEAIAGL PCSVEIASEY RYRAAYANPK HLIVTISQSG
360 370 380 390 400
ETLDTMEALK YAKSLGHLHT LSICNVPESA IPRASELVCY TRAGAEIGVA
410 420 430 440 450
STKAFTTQLA VLFQLTMVLG TLQGRISDAE EAEYLEQLRF LPGSVQHALN
460 470 480 490 500
LEPQIMAWAE RFSPKENALF LGRGLHYPIA LEGALKLKEI SYIHAEAYPA
510 520 530 540 550
GELKHGPLAL VDAAMPVVVI APNDRLLEKV KSNMQEVRAR GGELFVFADQ
560 570 580 590 600
DSHFSDSEGV HVIRTPRHAG VLSPVIHTIP VQLLAYHTAL ARGTDVDKPR

NLAKSVTVE
Length:609
Mass (Da):65,875
Last modified:January 23, 2007 - v2
Checksum:iE4F792B4EDE003BC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE008923 Genomic DNA Translation: AAM38480.1
RefSeqiWP_011052419.1, NC_003919.1

Genome annotation databases

EnsemblBacteriaiAAM38480; AAM38480; XAC3637
KEGGixac:XAC3637

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE008923 Genomic DNA Translation: AAM38480.1
RefSeqiWP_011052419.1, NC_003919.1

3D structure databases

ProteinModelPortaliQ8PGH9
SMRiQ8PGH9
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi190486.XAC3637

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAM38480; AAM38480; XAC3637
KEGGixac:XAC3637

Phylogenomic databases

eggNOGiENOG4105C46 Bacteria
COG0449 LUCA
HOGENOMiHOG000258896
KOiK00820
OMAiGTSHYAG
OrthoDBiPOG091H0061

Enzyme and pathway databases

BioCyciXAXO190486:XAC_RS18390-MONOMER

Family and domain databases

CDDicd05008 SIS_GlmS_GlmD_1, 1 hit
cd05009 SIS_GlmS_GlmD_2, 1 hit
Gene3Di3.60.20.10, 1 hit
HAMAPiMF_00164 GlmS, 1 hit
InterProiView protein in InterPro
IPR017932 GATase_2_dom
IPR035466 GlmS/AgaS_SIS
IPR035490 GlmS/FrlB_SIS
IPR005855 GlmS_trans
IPR029055 Ntn_hydrolases_N
IPR001347 SIS
PANTHERiPTHR10937:SF0 PTHR10937:SF0, 1 hit
PfamiView protein in Pfam
PF01380 SIS, 2 hits
SUPFAMiSSF56235 SSF56235, 1 hit
TIGRFAMsiTIGR01135 glmS, 1 hit
PROSITEiView protein in PROSITE
PS51278 GATASE_TYPE_2, 1 hit
PS51464 SIS, 2 hits
ProtoNetiSearch...

Entry informationi

Entry nameiGLMS_XANAC
AccessioniPrimary (citable) accession number: Q8PGH9
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 10, 2002
Last sequence update: January 23, 2007
Last modified: October 10, 2018
This is version 105 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again