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UniProtKB - Q8NMD6 (Q8NMD6_CORGL)
Protein
Submitted name:
Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific
Gene
Cgl2642
Organism
Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / BCRC 11384 / JCM 1318 / LMG 3730 / NCIMB 10025)
Status
Functioni
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Active sitei | 26 | Phosphocysteine intermediate; for EIIB activityPROSITE-ProRule annotation | 1 |
GO - Molecular functioni
- kinase activity Source: UniProtKB-KW
- protein-N(PI)-phosphohistidine-sugar phosphotransferase activity Source: InterPro
GO - Biological processi
- phosphoenolpyruvate-dependent sugar phosphotransferase system Source: UniProtKB-KW
Keywordsi
Molecular function | KinaseARBA annotation, Transferase |
Biological process | Phosphotransferase systemARBA annotation, Sugar transportARBA annotation, Transport |
Enzyme and pathway databases
BioCyci | CORYNE:G18NG-12259-MONOMER |
Protein family/group databases
TCDBi | 4.A.1.2.12, the pts glucose-glucoside (glc) family |
Names & Taxonomyi
Protein namesi | Submitted name: Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specificImported (EC:2.7.1.191Imported) |
Gene namesi | Ordered Locus Names:Cgl2642Imported |
Organismi | Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / BCRC 11384 / JCM 1318 / LMG 3730 / NCIMB 10025)Imported |
Taxonomic identifieri | 196627 [NCBI] |
Taxonomic lineagei | Bacteria › Actinobacteria › Corynebacteriales › Corynebacteriaceae › Corynebacterium › |
Proteomesi |
|
Subcellular locationi
Other locations
- Membrane ARBA annotation; Multi-pass membrane protein ARBA annotation
Plasma Membrane
- plasma membrane Source: UniProtKB-KW
Other locations
- integral component of membrane Source: UniProtKB-KW
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 113 – 135 | HelicalSequence analysisAdd BLAST | 23 | |
Transmembranei | 155 – 176 | HelicalSequence analysisAdd BLAST | 22 | |
Transmembranei | 188 – 209 | HelicalSequence analysisAdd BLAST | 22 | |
Transmembranei | 229 – 248 | HelicalSequence analysisAdd BLAST | 20 | |
Transmembranei | 260 – 282 | HelicalSequence analysisAdd BLAST | 23 | |
Transmembranei | 302 – 320 | HelicalSequence analysisAdd BLAST | 19 | |
Transmembranei | 341 – 364 | HelicalSequence analysisAdd BLAST | 24 | |
Transmembranei | 376 – 396 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 408 – 435 | HelicalSequence analysisAdd BLAST | 28 | |
Transmembranei | 441 – 464 | HelicalSequence analysisAdd BLAST | 24 |
Keywords - Cellular componenti
Cell membraneARBA annotation, MembraneStructurei
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 4 – 87 | PTS EIIB type-1InterPro annotationAdd BLAST | 84 | |
Domaini | 121 – 483 | PTS EIIC type-1InterPro annotationAdd BLAST | 363 | |
Domaini | 519 – 627 | PTS EIIA type-1InterPro annotationAdd BLAST | 109 |
Keywords - Domaini
Transmembrane, Transmembrane helixSequence analysisARBA annotationPhylogenomic databases
eggNOGi | COG1263, Bacteria COG1264, Bacteria COG2190, Bacteria |
HOGENOMi | CLU_012312_2_1_11 |
OMAi | LITHAGW |
Family and domain databases
CDDi | cd00212, PTS_IIB_glc, 1 hit |
Gene3Di | 2.70.70.10, 1 hit 3.30.1360.60, 1 hit |
InterProi | View protein in InterPro IPR011055, Dup_hybrid_motif IPR036878, Glu_permease_IIB IPR018113, PTrfase_EIIB_Cys IPR001127, PTS_EIIA_1_perm IPR003352, PTS_EIIC IPR013013, PTS_EIIC_1 IPR001996, PTS_IIB_1 IPR010973, PTS_IIBC_sucr |
Pfami | View protein in Pfam PF00358, PTS_EIIA_1, 1 hit PF00367, PTS_EIIB, 1 hit PF02378, PTS_EIIC, 1 hit |
SUPFAMi | SSF51261, SSF51261, 1 hit SSF55604, SSF55604, 1 hit |
TIGRFAMsi | TIGR00830, PTBA, 1 hit TIGR01996, PTS-II-BC-sucr, 1 hit |
PROSITEi | View protein in PROSITE PS51093, PTS_EIIA_TYPE_1, 1 hit PS51098, PTS_EIIB_TYPE_1, 1 hit PS01035, PTS_EIIB_TYPE_1_CYS, 1 hit PS51103, PTS_EIIC_TYPE_1, 1 hit |
i Sequence
Sequence statusi: Complete.
Q8NMD6-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MDHKDLAQRI LRDIGGEDNI VAAAHCATRL RLVLKDTKDV DRQSLDDDPD
60 70 80 90 100
LKGTFETGGM FQIIVGPGDV DHVFKELDDA TSKDIAVSTE QLKDVVANNA
110 120 130 140 150
NWFSRAVKVL ADIFVPLIPI LVGGGLLMAI NNVLVAQDLF GPQSLVEMFP
160 170 180 190 200
QISGVAEMIN LMASAPFAFL PVLVGFTATK RFGGNEFLGA GIGMAMVFPS
210 220 230 240 250
LVNGYDVAAT MAAGEMPMWS LFGLDVAQAG YQGTVLPVLV VSWILATIEK
260 270 280 290 300
FLHKRLKGTA DFLITPVLTL LLTGFLTFIA IGPAMRWVGD VLAHGLQGLY
310 320 330 340 350
DFGGPVGGLL FGLVYSPIVI TGLHQSFPPI ELELFNQGGS FIFATASMAN
360 370 380 390 400
IAQGAACLAV FFLAKSEKLK GLAGASGVSA VLGITEPAIF GVNLRLRWPF
410 420 430 440 450
FIGIGTAAIG GALIALFNIK AVALGAAGFL GVVSIDAPDM VMFLVCAVVT
460 470 480 490 500
FFIAFGAAIA YGLYLVRRNG SIDPDATAAP VPAGTTKAEA EAPAEFSNDS
510 520 530 540 550
TIIQAPLTGE AIALSSVSDA MFASGKLGSG VAIVPTKGQL VSPVSGKIVV
560 570 580 590 600
AFPSGHAFAV RTKAEDGSNV DILMHIGFDT VNLNGTHFNP LKKQGDEVKA
610 620 630 640 650
GELLCEFDID AIKAAGYEVT TPIVVSNYKK TGPVNTYGLG EIEAGANLLN
660
VAKKEAVPAT P
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BA000036 Genomic DNA Translation: BAC00036.1 |
RefSeqi | NP_601842.1, NC_003450.3 WP_011015272.1, NC_006958.1 |
Genome annotation databases
EnsemblBacteriai | BAC00036; BAC00036; BAC00036 |
KEGGi | cgl:NCgl2553 |
PATRICi | fig|196627.13.peg.2578 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BA000036 Genomic DNA Translation: BAC00036.1 |
RefSeqi | NP_601842.1, NC_003450.3 WP_011015272.1, NC_006958.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
STRINGi | 196627.cg2925 |
Protein family/group databases
TCDBi | 4.A.1.2.12, the pts glucose-glucoside (glc) family |
Genome annotation databases
EnsemblBacteriai | BAC00036; BAC00036; BAC00036 |
KEGGi | cgl:NCgl2553 |
PATRICi | fig|196627.13.peg.2578 |
Phylogenomic databases
eggNOGi | COG1263, Bacteria COG1264, Bacteria COG2190, Bacteria |
HOGENOMi | CLU_012312_2_1_11 |
OMAi | LITHAGW |
Enzyme and pathway databases
BioCyci | CORYNE:G18NG-12259-MONOMER |
Family and domain databases
CDDi | cd00212, PTS_IIB_glc, 1 hit |
Gene3Di | 2.70.70.10, 1 hit 3.30.1360.60, 1 hit |
InterProi | View protein in InterPro IPR011055, Dup_hybrid_motif IPR036878, Glu_permease_IIB IPR018113, PTrfase_EIIB_Cys IPR001127, PTS_EIIA_1_perm IPR003352, PTS_EIIC IPR013013, PTS_EIIC_1 IPR001996, PTS_IIB_1 IPR010973, PTS_IIBC_sucr |
Pfami | View protein in Pfam PF00358, PTS_EIIA_1, 1 hit PF00367, PTS_EIIB, 1 hit PF02378, PTS_EIIC, 1 hit |
SUPFAMi | SSF51261, SSF51261, 1 hit SSF55604, SSF55604, 1 hit |
TIGRFAMsi | TIGR00830, PTBA, 1 hit TIGR01996, PTS-II-BC-sucr, 1 hit |
PROSITEi | View protein in PROSITE PS51093, PTS_EIIA_TYPE_1, 1 hit PS51098, PTS_EIIB_TYPE_1, 1 hit PS01035, PTS_EIIB_TYPE_1_CYS, 1 hit PS51103, PTS_EIIC_TYPE_1, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | Q8NMD6_CORGL | |
Accessioni | Q8NMD6Primary (citable) accession number: Q8NMD6 Secondary accession number(s): Q6M2J8 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | October 1, 2002 |
Last sequence update: | October 1, 2002 | |
Last modified: | February 10, 2021 | |
This is version 140 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |