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Entry version 146 (07 Apr 2021)
Sequence version 1 (01 Oct 2002)
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Protein
Submitted name:

Polyketide synthase modules and related proteins

Gene

Cgl2871

Organism
Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / BCRC 11384 / JCM 1318 / LMG 3730 / NCIMB 10025)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionMultifunctional enzymeARBA annotation, TransferaseARBA annotation

Enzyme and pathway databases

BioCyc Collection of Pathway/Genome Databases

More...
BioCyci
CORYNE:G18NG-12489-MONOMER

Protein family/group databases

ESTHER database of the Alpha/Beta-hydrolase fold superfamily of proteins

More...
ESTHERi
corgl-CGL2871, Thioesterase

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Polyketide synthase modules and related proteinsImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Ordered Locus Names:Cgl2871Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiCorynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / BCRC 11384 / JCM 1318 / LMG 3730 / NCIMB 10025)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri196627 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteriaActinobacteriaCorynebacterialesCorynebacteriaceaeCorynebacterium
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000582 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei48O-(pantetheine 4'-phosphoryl)serinePROSITE-ProRule annotation1
Modified residuei1173O-(pantetheine 4'-phosphoryl)serinePROSITE-ProRule annotation1

Keywords - PTMi

PhosphopantetheinePROSITE-ProRule annotationARBA annotation, PhosphoproteinARBA annotation

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
196627.cg3178

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q8NLR7

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini11 – 88CarrierInterPro annotationAdd BLAST78
Domaini1139 – 1213CarrierInterPro annotationAdd BLAST75

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1227 – 1250DisorderedSequence analysisAdd BLAST24

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
COG0236, Bacteria
COG3319, Bacteria
COG3321, Bacteria

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_000022_26_1_11

Identification of Orthologs from Complete Genome Data

More...
OMAi
QLYVHGH

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.10.1200.10, 2 hits
3.40.47.10, 1 hit
3.40.50.1820, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR029058, AB_hydrolase
IPR036736, ACP-like_sf
IPR014043, Acyl_transferase
IPR016035, Acyl_Trfase/lysoPLipase
IPR018201, Ketoacyl_synth_AS
IPR014031, Ketoacyl_synth_C
IPR014030, Ketoacyl_synth_N
IPR016036, Malonyl_transacylase_ACP-bd
IPR032821, PKS_assoc
IPR020841, PKS_Beta-ketoAc_synthase_dom
IPR020806, PKS_PP-bd
IPR020802, PKS_thioesterase
IPR009081, PP-bd_ACP
IPR001031, Thioesterase
IPR016039, Thiolase-like

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00698, Acyl_transf_1, 1 hit
PF16197, KAsynt_C_assoc, 1 hit
PF00109, ketoacyl-synt, 1 hit
PF02801, Ketoacyl-synt_C, 1 hit
PF00550, PP-binding, 2 hits
PF00975, Thioesterase, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00827, PKS_AT, 1 hit
SM00825, PKS_KS, 1 hit
SM00823, PKS_PP, 2 hits
SM00824, PKS_TE, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF47336, SSF47336, 2 hits
SSF52151, SSF52151, 1 hit
SSF53474, SSF53474, 1 hit
SSF53901, SSF53901, 1 hit
SSF55048, SSF55048, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00606, B_KETOACYL_SYNTHASE, 1 hit
PS50075, CARRIER, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q8NLR7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MEQSQSSDQK MTVEQVRTWL RDWVVRTTGI PVEEVTDDKA METFGLSSRD
60 70 80 90 100
VVVLSGELEN LLDTSLDATI AYEYPTIRSL AQRLVEGEPR RAHTQRELNF
110 120 130 140 150
SAVSDSPGSH DIAVVGMAAR YPGAESLEDM WKLLVEGRDG ISDLPIGRWS
160 170 180 190 200
EYAGDEVMSR KMEEFSTIGG YLSDISSFDA EFFGLSPLEA ANMDPQQRIL
210 220 230 240 250
LELTWEALEY ARIAPNTLRG EAVGVFIGSS NNDYGMMIAA DPAEAHPYAL
260 270 280 290 300
TGTSSAIVAN RINYAFDFRG PSVNVDTACS SSLVAVHQAV RALRNGEADH
310 320 330 340 350
AIAGGVNILA SPFVTTAFAE LGVISPTGKI HAFSDDADGF VRSDGAGVVV
360 370 380 390 400
LKRVDDAIRD GDKIIGVIKG SAVNSDGHSN GLTAPNPDAQ VDVLQRAYVD
410 420 430 440 450
AQVDPTTVDY VEAHGTGTIL GDPIEATALG AVLGYGRDAS TPTLLGSAKS
460 470 480 490 500
NFGHTESAAG IAGVIKVLLA LQNKTLPPTV NFAGPNRYID FDAERLEVVE
510 520 530 540 550
DPREWPEYNG HAVAGVSAFG FGGTNAHVVI SEYNAEDYET RAPKEALLPD
560 570 580 590 600
QQVALPVSGH LPSRRRQAAA DLADFLEGRK DCDLTPVARA LAGRNHGRSR
610 620 630 640 650
AVVLASTIEE AVKRLRQVAE GKVSVGISAA DSPAANGPVF VYSGFGSQHR
660 670 680 690 700
LMIKELCSIS PQFRERIEEL DEMVKFESGW SIMKLVLDDE QTYDTETAQV
710 720 730 740 750
VITAIQIALT DLLASFGVKP AAVMGMSMGE IAAAYAAGGL SDRDTMLIAS
760 770 780 790 800
HRSRLMGEGE KSLAEDQLGA MAVVEFAAAD LDKFIEENPE YKGIEPAVYA
810 820 830 840 850
GPGMTTVGGP RDAVVQFVEK LESEDKFARL LNVKGAGHTS AVEPLLGELA
860 870 880 890 900
GEIAGIEPLP LQIPLFSSVD QGVTYPVGAV VHDADYMLRC TRQSVYFQDS
910 920 930 940 950
TEAAFAAGHN TLVEISPNPV ALMGMMNTAF TVGKPDAQLL FSLKRKVPEA
960 970 980 990 1000
ESLRDLLAKL YVNGANVDFS ALYGEGETID PPHITWKHQR FWTSARPSSG
1010 1020 1030 1040 1050
ASLDLPGFRV NLPNNTVAFS TAAELAPSAV AIMEAAAMAV TPGSSVDAVD
1060 1070 1080 1090 1100
ERDMLPPSGE ITTIVTRSLG GLSLSVYKIE GTTSTLVAEG FAANPGFAAA
1110 1120 1130 1140 1150
SSFDGPGYDG FNTDYSDQPD PRSDLPLDIE AVRWDPATET VEERMRAIVS
1160 1170 1180 1190 1200
EAMGYDVDDL PRELPLIDLG LDSLMGMRIK NRIENDFQIP PLQVQALRDA
1210 1220 1230 1240 1250
SVADVVIMVE NMVAGRSSET LVDATPQVPA EAAGEAQAAE SSASGEDVQG
1260 1270 1280 1290 1300
VGVAPRDASE RMVFGTWAGL TGAAAAGVTS KLPQIDVDTA TAIAERLTER
1310 1320 1330 1340 1350
SGIEISTEQV LAAETLEPLS DLVREGLETE VQGNIRVLRG RAEGSTKPAV
1360 1370 1380 1390 1400
FMFHPAGGSS VVYQPLMRRL PEDVPVYGVE RLEGDLADRA AAYVDDIKKY
1410 1420 1430 1440 1450
SDGFPVVLGG WSFGGAVAFE VAHQLVGSDV EVATVALLDT VQPSNPAPDT
1460 1470 1480 1490 1500
AEETRARWTR YADFAKKTYG LDFEVPFEIL DTIGEDGMLS MMTDFLANTD
1510 1520 1530 1540 1550
ASEHGLSAGV LEHQRASFVD NRILAKLNFA DWANVEAPVI LFRAERMHDG
1560 1570 1580 1590 1600
AIELEPNYAK IDQDGGWSGI VNDLEIVQLN GDHLAVVDEP EIGTVGAHLS
1610
RRIDEISRKN
Length:1,610
Mass (Da):172,366
Last modified:October 1, 2002 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iBEF38D6C8BF0D694
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
BA000036 Genomic DNA Translation: BAC00265.1

NCBI Reference Sequences

More...
RefSeqi
NP_602063.1, NC_003450.3
WP_011015451.1, NC_006958.1

Genome annotation databases

Ensembl bacterial and archaeal genome annotation project

More...
EnsemblBacteriai
BAC00265; BAC00265; BAC00265

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
cgl:NCgl2773

Pathosystems Resource Integration Center (PATRIC)

More...
PATRICi
fig|196627.13.peg.2803

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000036 Genomic DNA Translation: BAC00265.1
RefSeqiNP_602063.1, NC_003450.3
WP_011015451.1, NC_006958.1

3D structure databases

SMRiQ8NLR7
ModBaseiSearch...

Protein-protein interaction databases

STRINGi196627.cg3178

Protein family/group databases

ESTHERicorgl-CGL2871, Thioesterase

Genome annotation databases

EnsemblBacteriaiBAC00265; BAC00265; BAC00265
KEGGicgl:NCgl2773
PATRICifig|196627.13.peg.2803

Phylogenomic databases

eggNOGiCOG0236, Bacteria
COG3319, Bacteria
COG3321, Bacteria
HOGENOMiCLU_000022_26_1_11
OMAiQLYVHGH

Enzyme and pathway databases

BioCyciCORYNE:G18NG-12489-MONOMER

Family and domain databases

Gene3Di1.10.1200.10, 2 hits
3.40.47.10, 1 hit
3.40.50.1820, 1 hit
InterProiView protein in InterPro
IPR029058, AB_hydrolase
IPR036736, ACP-like_sf
IPR014043, Acyl_transferase
IPR016035, Acyl_Trfase/lysoPLipase
IPR018201, Ketoacyl_synth_AS
IPR014031, Ketoacyl_synth_C
IPR014030, Ketoacyl_synth_N
IPR016036, Malonyl_transacylase_ACP-bd
IPR032821, PKS_assoc
IPR020841, PKS_Beta-ketoAc_synthase_dom
IPR020806, PKS_PP-bd
IPR020802, PKS_thioesterase
IPR009081, PP-bd_ACP
IPR001031, Thioesterase
IPR016039, Thiolase-like
PfamiView protein in Pfam
PF00698, Acyl_transf_1, 1 hit
PF16197, KAsynt_C_assoc, 1 hit
PF00109, ketoacyl-synt, 1 hit
PF02801, Ketoacyl-synt_C, 1 hit
PF00550, PP-binding, 2 hits
PF00975, Thioesterase, 1 hit
SMARTiView protein in SMART
SM00827, PKS_AT, 1 hit
SM00825, PKS_KS, 1 hit
SM00823, PKS_PP, 2 hits
SM00824, PKS_TE, 1 hit
SUPFAMiSSF47336, SSF47336, 2 hits
SSF52151, SSF52151, 1 hit
SSF53474, SSF53474, 1 hit
SSF53901, SSF53901, 1 hit
SSF55048, SSF55048, 1 hit
PROSITEiView protein in PROSITE
PS00606, B_KETOACYL_SYNTHASE, 1 hit
PS50075, CARRIER, 2 hits

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiQ8NLR7_CORGL
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q8NLR7
Secondary accession number(s): Q6M1Y7
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: October 1, 2002
Last sequence update: October 1, 2002
Last modified: April 7, 2021
This is version 146 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
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