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Entry version 52 (22 Apr 2020)
Sequence version 1 (01 Oct 2002)
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Protein
Submitted name:

Amylopullulanase

Gene

apu

Organism
Thermococcus litoralis
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

Protein family/group databases

Carbohydrate-Active enZymes

More...
CAZyi
GH57 Glycoside Hydrolase Family 57

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
AmylopullulanaseImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:apuImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiThermococcus litoralisImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri2265 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiArchaeaEuryarchaeotaThermococciThermococcalesThermococcaceaeThermococcus

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini33 – 465Glyco_hydro_57InterPro annotationAdd BLAST433
Domaini788 – 1020Glucodextran_CInterPro annotationAdd BLAST233

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1029 – 1069DisorderedSequence analysisAdd BLAST41

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi1038 – 1066PolarSequence analysisAdd BLAST29

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR027552 CGP_CTERM
IPR019248 Glucodextran_C
IPR011330 Glyco_hydro/deAcase_b/a-brl
IPR004300 Glyco_hydro_57_N

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF09985 Glucodextran_C, 1 hit
PF03065 Glyco_hydro_57, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF88713 SSF88713, 1 hit

TIGRFAMs; a protein family database

More...
TIGRFAMsi
TIGR04288 CGP_CTERM, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q8NKS8-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MKKGLAMFLI FLVALSIAEV GVKAEEPKPL NVIIVWHQHQ PYYYDPIQDI
60 70 80 90 100
YTRPWVRLHA ANNYWKMANY LSKYPDVHVA IDLSGSLIAQ LADYMNGKKD
110 120 130 140 150
TYQIVTEKIA NGEPLTLEDK WFMLQAPGGF FDHTIPWNGE PVADENGNPY
160 170 180 190 200
REQWDRYAEL KDKRNNAFKK YANLPLNEQK VKITAEFTEQ DYIDLAVLFN
210 220 230 240 250
LAWIDYNYII NTPELKALYD KVDVGGYTKE DVATVLKHQM WLLNHTFEEH
260 270 280 290 300
EKINYLLGNG NVEVTVVPYA HPIGPLLNDF GWYEDFDAHV KKAHELYKKY
310 320 330 340 350
LGDNRVEPQG GWAAESALND KTLEILTNNG WKWVMTDQMV LDILGIPNTV
360 370 380 390 400
ENYYKPWVAE FNGKKIYLFP RNHDLSDRVG FRYSGMNQYQ AVEDFVNELL
410 420 430 440 450
KVQKENYDGS LVYVVTLDGE NPWEHYPFDG KIFLEELYKK LTELQKQGLI
460 470 480 490 500
RTVTPSEYIQ MYGDKANKLT PKLMKRLDFT TEERVNALLK AQSLGELYDM
510 520 530 540 550
AGVEENMQWP ESSWVDGTLS TWIGEPQENL GWYWLYLGRK ALFENKNKVV
560 570 580 590 600
DWNTAYEYLL RAEASDWFWW YGSDQDSGQD YTFDRYLKTY LYEMYKFAGL
610 620 630 640 650
EIPSYLFGNY FPNGEPYAIR ELTGLPEGEK KSWSSLSPIA EGVELYFDEQ
660 670 680 690 700
GLHFVVKTTK EFEISIFEPG KVMGNTFTLL QTKPSELRYD IFPFSKDSVG
710 720 730 740 750
LMITKHIIVK EGKAEVYKAT DYENSEKVGE VDVKETDGGV EVIVPFDYLD
760 770 780 790 800
SPSDFYFAVS TVNDQGELEI ITNPIEVKLP KQVEGIVVAE IKDIEWDDHG
810 820 830 840 850
PGTYTYATNK VFVPGHLDLL KVRILEKPSS YVFEYYFKDL GDNSWNGPNG
860 870 880 890 900
FSLQIIEAYF DFKEGGNTSA IKMFPDGPGS NVDLDPEHPW DVALRIAGWD
910 920 930 940 950
YGNIIVLPDG TSYQGEMKIS ADPVKNAIVV EVPKKYLEIS KDYGLYGAIL
960 970 980 990 1000
VGSQDGYEPD KWRPVAVDAE EWKGGGADVN AVIAGVAPRV YDLLVPEDFK
1010 1020 1030 1040 1050
PTQEEQLSSY DAENGKRAIV KMIPLFGVEE KPSETETPTE TESPTPSETS
1060 1070 1080
STVSPSSTSS PSPTETGGIC GPAALVGLAL IPLLLRRRW
Length:1,089
Mass (Da):124,218
Last modified:October 1, 2002 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i82C4808E266EA891
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AB054186 Genomic DNA Translation: BAC10983.1

Genome annotation databases

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
16549640

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB054186 Genomic DNA Translation: BAC10983.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein family/group databases

CAZyiGH57 Glycoside Hydrolase Family 57

Genome annotation databases

GeneIDi16549640

Family and domain databases

InterProiView protein in InterPro
IPR027552 CGP_CTERM
IPR019248 Glucodextran_C
IPR011330 Glyco_hydro/deAcase_b/a-brl
IPR004300 Glyco_hydro_57_N
PfamiView protein in Pfam
PF09985 Glucodextran_C, 1 hit
PF03065 Glyco_hydro_57, 1 hit
SUPFAMiSSF88713 SSF88713, 1 hit
TIGRFAMsiTIGR04288 CGP_CTERM, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiQ8NKS8_THELI
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q8NKS8
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: October 1, 2002
Last sequence update: October 1, 2002
Last modified: April 22, 2020
This is version 52 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
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