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Protein

Spermatogenesis-associated protein 22

Gene

SPATA22

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Meiosis-specific protein required for homologous recombination in meiosis I.By similarity

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processMeiosis

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Spermatogenesis-associated protein 22
Alternative name(s):
Testis development protein NYD-SP20
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:SPATA22
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 17

Organism-specific databases

Eukaryotic Pathogen Database Resources

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EuPathDBi
HostDB:ENSG00000141255.12

Human Gene Nomenclature Database

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HGNCi
HGNC:30705 SPATA22

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
617673 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q8NHS9

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Chromosome

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
84690

Open Targets

More...
OpenTargetsi
ENSG00000141255

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA142670887

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
SPATA22

Domain mapping of disease mutations (DMDM)

More...
DMDMi
296452914

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002516051 – 363Spermatogenesis-associated protein 22Add BLAST363

Proteomic databases

Encyclopedia of Proteome Dynamics

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EPDi
Q8NHS9

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q8NHS9

PeptideAtlas

More...
PeptideAtlasi
Q8NHS9

PRoteomics IDEntifications database

More...
PRIDEi
Q8NHS9

ProteomicsDB human proteome resource

More...
ProteomicsDBi
73750
73751 [Q8NHS9-2]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q8NHS9

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q8NHS9

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Highly expressed in adult testis.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

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Bgeei
ENSG00000141255 Expressed in 90 organ(s), highest expression level in testis

CleanEx database of gene expression profiles

More...
CleanExi
HS_SPATA22

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q8NHS9 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q8NHS9 HS

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Component of a multiprotein complex with MEIOB and SPATA22.By similarity

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction_section%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="http://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated on a monthly basis. Each binary interaction is displayed on a separate line.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
124205, 9 interactors

Protein interaction database and analysis system

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IntActi
Q8NHS9, 6 interactors

Molecular INTeraction database

More...
MINTi
Q8NHS9

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000380354

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

More...
ProteinModelPortali
Q8NHS9

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410IVC3 Eukaryota
ENOG4111W26 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000018151

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000038032

The HOVERGEN Database of Homologous Vertebrate Genes

More...
HOVERGENi
HBG093993

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q8NHS9

KEGG Orthology (KO)

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KOi
K22421

Identification of Orthologs from Complete Genome Data

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OMAi
WEAMNPE

Database of Orthologous Groups

More...
OrthoDBi
938712at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q8NHS9

TreeFam database of animal gene trees

More...
TreeFami
TF332549

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR033536 Spata22

The PANTHER Classification System

More...
PANTHERi
PTHR35258 PTHR35258, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (3+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 3 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 3 described isoforms and 7 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q8NHS9-1) [UniParc]FASTAAdd to basket
Also known as: NYD-SP20C, NYD-SP20D

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MKRSLNENSA RSTAGCLPVP LFNQKKRNRQ PLTSNPLKDD SGISTPSDNY
60 70 80 90 100
DFPPLPTDWA WEAVNPELAP VMKTVDTGQI PHSVSRPLRS QDSVFNSIQS
110 120 130 140 150
NTGRSQGGWS YRDGNKNTSL KTWNKNDFKP QCKRTNLVAN DGKNSCPVSS
160 170 180 190 200
GAQQQKQLRI PEPPNLSRNK ETELLRQTHS SKISGCTMRG LDKNSALQTL
210 220 230 240 250
KPNFQQNQYK KQMLDDIPED NTLKETSLYQ LQFKEKASSL RIISAVIESM
260 270 280 290 300
KYWREHAQKT VLLFEVLAVL DSAVTPGPYY SKTFLMRDGK NTLPCVFYEI
310 320 330 340 350
DRELPRLIRG RVHRCVGNYD QKKNIFQCVS VRPASVSEQK TFQAFVKIAD
360
VEMQYYINVM NET
Length:363
Mass (Da):41,318
Last modified:May 18, 2010 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i71E6C8E4BF2526B8
GO
Isoform 2 (identifier: Q8NHS9-2) [UniParc]FASTAAdd to basket
Also known as: NYD-SP20B

The sequence of this isoform differs from the canonical sequence as follows:
     15-57: Missing.

Show »
Length:320
Mass (Da):36,566
Checksum:iBF3BF821DB381707
GO
Isoform 3 (identifier: Q8NHS9-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     268-363: AVLDSAVTPG...QYYINVMNET → GS

Note: No experimental confirmation available.
Show »
Length:269
Mass (Da):30,380
Checksum:iC77EE4552F17BCC2
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 7 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
F5GWB9F5GWB9_HUMAN
Spermatogenesis-associated protein ...
SPATA22
347Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
I3L2B9I3L2B9_HUMAN
Spermatogenesis-associated protein ...
SPATA22
168Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
I3L4D7I3L4D7_HUMAN
Spermatogenesis-associated protein ...
SPATA22
164Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
I3L517I3L517_HUMAN
Spermatogenesis-associated protein ...
SPATA22
148Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
I3L4R7I3L4R7_HUMAN
Spermatogenesis-associated protein ...
SPATA22
209Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
I3L3S6I3L3S6_HUMAN
Spermatogenesis-associated protein ...
SPATA22
49Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
I3L1L5I3L1L5_HUMAN
Spermatogenesis-associated protein ...
SPATA22
85Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti6N → S in AAK51120 (PubMed:15713825).Curated1
Sequence conflicti6N → S in AAK53408 (PubMed:15713825).Curated1
Sequence conflicti6N → S in AAK61373 (PubMed:15713825).Curated1
Sequence conflicti6N → S in AAK61374 (PubMed:15713825).Curated1
Sequence conflicti84V → A in AAK53408 (PubMed:15713825).Curated1
Sequence conflicti84V → A in AAK61373 (PubMed:15713825).Curated1
Sequence conflicti84V → A in AAK61374 (PubMed:15713825).Curated1
Sequence conflicti106Q → R in BAG63323 (PubMed:14702039).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_027693112R → T. Corresponds to variant dbSNP:rs2291604Ensembl.1
Natural variantiVAR_027694148V → M1 PublicationCorresponds to variant dbSNP:rs1488690Ensembl.1
Natural variantiVAR_027695155Q → R. Corresponds to variant dbSNP:rs11556563Ensembl.1
Natural variantiVAR_027696160I → T1 PublicationCorresponds to variant dbSNP:rs1488689Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting. The information stored in this subsection is used to automatically construct alternative protein sequence(s) for display.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_02076315 – 57Missing in isoform 2. 1 PublicationAdd BLAST43
Alternative sequenceiVSP_044858268 – 363AVLDS…VMNET → GS in isoform 3. 1 PublicationAdd BLAST96

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AF367472 mRNA Translation: AAK53408.1
AY032684 mRNA Translation: AAK51120.1
AY035867 mRNA Translation: AAK61373.1
AY035868 mRNA Translation: AAK61374.1
AK301892 mRNA Translation: BAG63323.1
AC025125 Genomic DNA No translation available.
CH471108 Genomic DNA Translation: EAW90508.1
CH471108 Genomic DNA Translation: EAW90509.1
CH471108 Genomic DNA Translation: EAW90510.1
CH471108 Genomic DNA Translation: EAW90511.1
BC029483 mRNA Translation: AAH29483.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS11027.1 [Q8NHS9-1]
CCDS54066.1 [Q8NHS9-2]
CCDS54067.1 [Q8NHS9-3]

NCBI Reference Sequences

More...
RefSeqi
NP_001164166.1, NM_001170695.1 [Q8NHS9-1]
NP_001164167.1, NM_001170696.1 [Q8NHS9-2]
NP_001164168.1, NM_001170697.1 [Q8NHS9-1]
NP_001164169.1, NM_001170698.1 [Q8NHS9-1]
NP_001164170.1, NM_001170699.1 [Q8NHS9-3]
NP_001308265.1, NM_001321336.1
NP_001308266.1, NM_001321337.1 [Q8NHS9-1]
NP_115987.2, NM_032598.4 [Q8NHS9-1]

UniGene gene-oriented nucleotide sequence clusters

More...
UniGenei
Hs.351068

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000268981; ENSP00000268981; ENSG00000141255 [Q8NHS9-3]
ENST00000355380; ENSP00000347541; ENSG00000141255 [Q8NHS9-2]
ENST00000397168; ENSP00000380354; ENSG00000141255 [Q8NHS9-1]
ENST00000572969; ENSP00000460187; ENSG00000141255 [Q8NHS9-1]
ENST00000573128; ENSP00000459580; ENSG00000141255 [Q8NHS9-1]
ENST00000575375; ENSP00000459329; ENSG00000141255 [Q8NHS9-1]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
84690

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:84690

UCSC genome browser

More...
UCSCi
uc002fvm.5 human [Q8NHS9-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF367472 mRNA Translation: AAK53408.1
AY032684 mRNA Translation: AAK51120.1
AY035867 mRNA Translation: AAK61373.1
AY035868 mRNA Translation: AAK61374.1
AK301892 mRNA Translation: BAG63323.1
AC025125 Genomic DNA No translation available.
CH471108 Genomic DNA Translation: EAW90508.1
CH471108 Genomic DNA Translation: EAW90509.1
CH471108 Genomic DNA Translation: EAW90510.1
CH471108 Genomic DNA Translation: EAW90511.1
BC029483 mRNA Translation: AAH29483.1
CCDSiCCDS11027.1 [Q8NHS9-1]
CCDS54066.1 [Q8NHS9-2]
CCDS54067.1 [Q8NHS9-3]
RefSeqiNP_001164166.1, NM_001170695.1 [Q8NHS9-1]
NP_001164167.1, NM_001170696.1 [Q8NHS9-2]
NP_001164168.1, NM_001170697.1 [Q8NHS9-1]
NP_001164169.1, NM_001170698.1 [Q8NHS9-1]
NP_001164170.1, NM_001170699.1 [Q8NHS9-3]
NP_001308265.1, NM_001321336.1
NP_001308266.1, NM_001321337.1 [Q8NHS9-1]
NP_115987.2, NM_032598.4 [Q8NHS9-1]
UniGeneiHs.351068

3D structure databases

ProteinModelPortaliQ8NHS9
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi124205, 9 interactors
IntActiQ8NHS9, 6 interactors
MINTiQ8NHS9
STRINGi9606.ENSP00000380354

PTM databases

iPTMnetiQ8NHS9
PhosphoSitePlusiQ8NHS9

Polymorphism and mutation databases

BioMutaiSPATA22
DMDMi296452914

Proteomic databases

EPDiQ8NHS9
PaxDbiQ8NHS9
PeptideAtlasiQ8NHS9
PRIDEiQ8NHS9
ProteomicsDBi73750
73751 [Q8NHS9-2]

Protocols and materials databases

The DNASU plasmid repository

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DNASUi
84690
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000268981; ENSP00000268981; ENSG00000141255 [Q8NHS9-3]
ENST00000355380; ENSP00000347541; ENSG00000141255 [Q8NHS9-2]
ENST00000397168; ENSP00000380354; ENSG00000141255 [Q8NHS9-1]
ENST00000572969; ENSP00000460187; ENSG00000141255 [Q8NHS9-1]
ENST00000573128; ENSP00000459580; ENSG00000141255 [Q8NHS9-1]
ENST00000575375; ENSP00000459329; ENSG00000141255 [Q8NHS9-1]
GeneIDi84690
KEGGihsa:84690
UCSCiuc002fvm.5 human [Q8NHS9-1]

Organism-specific databases

Comparative Toxicogenomics Database

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CTDi
84690
DisGeNETi84690
EuPathDBiHostDB:ENSG00000141255.12

GeneCards: human genes, protein and diseases

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GeneCardsi
SPATA22
HGNCiHGNC:30705 SPATA22
MIMi617673 gene
neXtProtiNX_Q8NHS9
OpenTargetsiENSG00000141255
PharmGKBiPA142670887

GenAtlas: human gene database

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GenAtlasi
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Phylogenomic databases

eggNOGiENOG410IVC3 Eukaryota
ENOG4111W26 LUCA
GeneTreeiENSGT00390000018151
HOGENOMiHOG000038032
HOVERGENiHBG093993
InParanoidiQ8NHS9
KOiK22421
OMAiWEAMNPE
OrthoDBi938712at2759
PhylomeDBiQ8NHS9
TreeFamiTF332549

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

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ChiTaRSi
SPATA22 human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

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GenomeRNAii
84690

Protein Ontology

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PROi
PR:Q8NHS9

The Stanford Online Universal Resource for Clones and ESTs

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SOURCEi
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Gene expression databases

BgeeiENSG00000141255 Expressed in 90 organ(s), highest expression level in testis
CleanExiHS_SPATA22
ExpressionAtlasiQ8NHS9 baseline and differential
GenevisibleiQ8NHS9 HS

Family and domain databases

InterProiView protein in InterPro
IPR033536 Spata22
PANTHERiPTHR35258 PTHR35258, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiSPT22_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q8NHS9
Secondary accession number(s): B4DXB1
, D3DTI9, J3KN63, Q969H3, Q96JT4
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 3, 2006
Last sequence update: May 18, 2010
Last modified: January 16, 2019
This is version 116 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  2. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  3. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  4. Human chromosome 17
    Human chromosome 17: entries, gene names and cross-references to MIM
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