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Entry version 117 (11 Dec 2019)
Sequence version 2 (03 Mar 2009)
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Protein

Putative phospholipase B-like 2

Gene

PLBD2

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Putative phospholipase.By similarity

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionHydrolase
Biological processLipid degradation, Lipid metabolism

Protein family/group databases

MEROPS protease database

More...
MEROPSi
C95.001

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Putative phospholipase B-like 2 (EC:3.1.1.-)
Alternative name(s):
76 kDa protein
Short name:
p76
LAMA-like protein 2
Lamina ancestor homolog 2
Phospholipase B domain-containing protein 2
Cleaved into the following 2 chains:
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:PLBD2
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 12

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000151176.7

Human Gene Nomenclature Database

More...
HGNCi
HGNC:27283 PLBD2

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q8NHP8

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Lysosome

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

More...
OpenTargetsi
ENSG00000151176

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA164724624

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q8NHP8 Tbio

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
PLBD2

Domain mapping of disease mutations (DMDM)

More...
DMDMi
224471847

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 411 PublicationAdd BLAST41
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_000028611042 – 589Putative phospholipase B-like 2Add BLAST548
ChainiPRO_000031407442 – 243Putative phospholipase B-like 2 32 kDa formAdd BLAST202
ChainiPRO_0000314075244 – 589Putative phospholipase B-like 2 45 kDa formAdd BLAST346

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi88N-linked (GlcNAc...) asparagine1 Publication1
Glycosylationi110N-linked (GlcNAc...) asparagine1 Publication1
<p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi142 ↔ 152By similarity
Glycosylationi231N-linked (GlcNAc...) asparagine1 Publication1
Glycosylationi436N-linked (GlcNAc...) asparagine1 Publication1
Glycosylationi465N-linked (GlcNAc...) asparagine2 Publications1
Disulfide bondi492 ↔ 495By similarity
Glycosylationi515N-linked (GlcNAc...) asparagine1 Publication1

<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM/processing</a> section describes post-translational modifications (PTMs). This subsection <strong>complements</strong> the information provided at the sequence level or describes modifications for which <strong>position-specific data is not yet available</strong>.<p><a href='/help/post-translational_modification' target='_top'>More...</a></p>Post-translational modificationi

The p76 protein is synthesized as a 80 kDa precursor which is then processed into a N-terminal 32 kDa form and a C-terminal 45 kDa form.
Glycosylated; contains mannose 6-phosphate sugars.2 Publications

Keywords - PTMi

Disulfide bond, Glycoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q8NHP8

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q8NHP8

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q8NHP8

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q8NHP8

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q8NHP8

PeptideAtlas

More...
PeptideAtlasi
Q8NHP8

PRoteomics IDEntifications database

More...
PRIDEi
Q8NHP8

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
26851
73733 [Q8NHP8-1]

PTM databases

GlyConnect protein glycosylation platform

More...
GlyConnecti
1700

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q8NHP8

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q8NHP8

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Ubiquitously expressed, with highest levels in heart, brain and liver.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000151176 Expressed in 201 organ(s), highest expression level in left adrenal gland

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q8NHP8 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q8NHP8 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA017163

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with IGF2R.

1 Publication

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
128208, 19 interactors

Protein interaction database and analysis system

More...
IntActi
Q8NHP8, 10 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000280800

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q8NHP8 protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q8NHP8

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the phospholipase B-like family.Curated

Keywords - Domaini

Signal

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG3774 Eukaryota
ENOG410XQRV LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00530000063509

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000006903

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q8NHP8

Identification of Orthologs from Complete Genome Data

More...
OMAi
GSAYWHQ

Database of Orthologous Groups

More...
OrthoDBi
724258at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q8NHP8

TreeFam database of animal gene trees

More...
TreeFami
TF315042

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.10.439.20, 1 hit
2.10.70.60, 1 hit
3.60.60.20, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR007000 PLipase_B-like
IPR043040 PLipase_B-like_dom1
IPR043041 PLipase_B-like_dom2
IPR043042 PLipase_B-like_dom3

The PANTHER Classification System

More...
PANTHERi
PTHR12370 PTHR12370, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF04916 Phospholip_B, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

This entry describes 2 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 1 potential isoform that is computationally mapped.Show allAlign All

Isoform 1 (identifier: Q8NHP8-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MVGQMYCYPG SHLARALTRA LALALVLALL VGPFLSGLAG AIPAPGGRWA
60 70 80 90 100
RDGQVPPASR SRSVLLDVSA GQLLMVDGRH PDAVAWANLT NAIRETGWAF
110 120 130 140 150
LELGTSGQYN DSLQAYAAGV VEAAVSEELI YMHWMNTVVN YCGPFEYEVG
160 170 180 190 200
YCERLKSFLE ANLEWMQEEM ESNPDSPYWH QVRLTLLQLK GLEDSYEGRV
210 220 230 240 250
SFPAGKFTIK PLGFLLLQLS GDLEDLELAL NKTKIKPSLG SGSCSALIKL
260 270 280 290 300
LPGQSDLLVA HNTWNNYQHM LRVIKKYWLQ FREGPWGDYP LVPGNKLVFS
310 320 330 340 350
SYPGTIFSCD DFYILGSGLV TLETTIGNKN PALWKYVRPR GCVLEWVRNI
360 370 380 390 400
VANRLASDGA TWADIFKRFN SGTYNNQWMI VDYKAFIPGG PSPGSRVLTI
410 420 430 440 450
LEQIPGMVVV ADKTSELYQK TYWASYNIPS FETVFNASGL QALVAQYGDW
460 470 480 490 500
FSYDGSPRAQ IFRRNQSLVQ DMDSMVRLMR YNDFLHDPLS LCKACNPQPN
510 520 530 540 550
GENAISARSD LNPANGSYPF QALRQRSHGG IDVKVTSMSL ARILSLLAAS
560 570 580
GPTWDQVPPF QWSTSPFSGL LHMGQPDLWK FAPVKVSWD
Length:589
Mass (Da):65,472
Last modified:March 3, 2009 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iD0D1BACCFBF756BB
GO
Isoform 2 (identifier: Q8NHP8-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     374-405: Missing.

Show »
Length:557
Mass (Da):61,885
Checksum:i6F9D325421593760
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
H0YIX0H0YIX0_HUMAN
Putative phospholipase B-like 2
PLBD2
52Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti521Q → K in AAH30618 (PubMed:15489334).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_06218754Q → P. Corresponds to variant dbSNP:rs7965471Ensembl.1
Natural variantiVAR_032075524R → C. Corresponds to variant dbSNP:rs12425042Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_055623374 – 405Missing in isoform 2. 1 PublicationAdd BLAST32

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AC010178 Genomic DNA No translation available.
BC030618 mRNA Translation: AAH30618.1
BC071832 mRNA No translation available.

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS53834.1 [Q8NHP8-2]
CCDS9168.1 [Q8NHP8-1]

NCBI Reference Sequences

More...
RefSeqi
NP_001153199.1, NM_001159727.1 [Q8NHP8-2]
NP_775813.2, NM_173542.3 [Q8NHP8-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000280800; ENSP00000280800; ENSG00000151176 [Q8NHP8-1]
ENST00000545182; ENSP00000443463; ENSG00000151176 [Q8NHP8-2]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
196463

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:196463

UCSC genome browser

More...
UCSCi
uc001tve.3 human [Q8NHP8-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC010178 Genomic DNA No translation available.
BC030618 mRNA Translation: AAH30618.1
BC071832 mRNA No translation available.
CCDSiCCDS53834.1 [Q8NHP8-2]
CCDS9168.1 [Q8NHP8-1]
RefSeqiNP_001153199.1, NM_001159727.1 [Q8NHP8-2]
NP_775813.2, NM_173542.3 [Q8NHP8-1]

3D structure databases

SMRiQ8NHP8
ModBaseiSearch...

Protein-protein interaction databases

BioGridi128208, 19 interactors
IntActiQ8NHP8, 10 interactors
STRINGi9606.ENSP00000280800

Protein family/group databases

MEROPSiC95.001

PTM databases

GlyConnecti1700
iPTMnetiQ8NHP8
PhosphoSitePlusiQ8NHP8

Polymorphism and mutation databases

BioMutaiPLBD2
DMDMi224471847

Proteomic databases

EPDiQ8NHP8
jPOSTiQ8NHP8
MassIVEiQ8NHP8
MaxQBiQ8NHP8
PaxDbiQ8NHP8
PeptideAtlasiQ8NHP8
PRIDEiQ8NHP8
ProteomicsDBi26851
73733 [Q8NHP8-1]

Genome annotation databases

EnsembliENST00000280800; ENSP00000280800; ENSG00000151176 [Q8NHP8-1]
ENST00000545182; ENSP00000443463; ENSG00000151176 [Q8NHP8-2]
GeneIDi196463
KEGGihsa:196463
UCSCiuc001tve.3 human [Q8NHP8-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
196463
EuPathDBiHostDB:ENSG00000151176.7

GeneCards: human genes, protein and diseases

More...
GeneCardsi
PLBD2
HGNCiHGNC:27283 PLBD2
HPAiHPA017163
neXtProtiNX_Q8NHP8
OpenTargetsiENSG00000151176
PharmGKBiPA164724624

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG3774 Eukaryota
ENOG410XQRV LUCA
GeneTreeiENSGT00530000063509
HOGENOMiHOG000006903
InParanoidiQ8NHP8
OMAiGSAYWHQ
OrthoDBi724258at2759
PhylomeDBiQ8NHP8
TreeFamiTF315042

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
PLBD2 human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
196463
PharosiQ8NHP8 Tbio

Protein Ontology

More...
PROi
PR:Q8NHP8
RNActiQ8NHP8 protein

Gene expression databases

BgeeiENSG00000151176 Expressed in 201 organ(s), highest expression level in left adrenal gland
ExpressionAtlasiQ8NHP8 baseline and differential
GenevisibleiQ8NHP8 HS

Family and domain databases

Gene3Di1.10.439.20, 1 hit
2.10.70.60, 1 hit
3.60.60.20, 1 hit
InterProiView protein in InterPro
IPR007000 PLipase_B-like
IPR043040 PLipase_B-like_dom1
IPR043041 PLipase_B-like_dom2
IPR043042 PLipase_B-like_dom3
PANTHERiPTHR12370 PTHR12370, 1 hit
PfamiView protein in Pfam
PF04916 Phospholip_B, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiPLBL2_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q8NHP8
Secondary accession number(s): F5H5E2
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 1, 2007
Last sequence update: March 3, 2009
Last modified: December 11, 2019
This is version 117 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Direct protein sequencing, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. Human chromosome 12
    Human chromosome 12: entries, gene names and cross-references to MIM
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