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Protein

Putative olfactory receptor 10J6

Gene

OR10J6P

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: -Protein uncertaini

Functioni

Odorant receptor.Curated

Caution

Could be the product of a pseudogene.Curated

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionG-protein coupled receptor, Receptor, Transducer
Biological processOlfaction, Sensory transduction

Enzyme and pathway databases

ReactomeiR-HSA-381753 Olfactory Signaling Pathway

Names & Taxonomyi

Protein namesi
Recommended name:
Putative olfactory receptor 10J6
Gene namesi
Name:OR10J6P
Synonyms:OR10J6
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Unplaced

Organism-specific databases

HGNCiHGNC:14994 OR10J6P
neXtProtiNX_Q8NGY7

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 25ExtracellularSequence analysisAdd BLAST25
Transmembranei26 – 46Helical; Name=1Sequence analysisAdd BLAST21
Topological domaini47 – 54CytoplasmicSequence analysis8
Transmembranei55 – 75Helical; Name=2Sequence analysisAdd BLAST21
Topological domaini76 – 99ExtracellularSequence analysisAdd BLAST24
Transmembranei100 – 120Helical; Name=3Sequence analysisAdd BLAST21
Topological domaini121 – 139CytoplasmicSequence analysisAdd BLAST19
Transmembranei140 – 160Helical; Name=4Sequence analysisAdd BLAST21
Topological domaini161 – 196ExtracellularSequence analysisAdd BLAST36
Transmembranei197 – 216Helical; Name=5Sequence analysisAdd BLAST20
Topological domaini217 – 236CytoplasmicSequence analysisAdd BLAST20
Transmembranei237 – 257Helical; Name=6Sequence analysisAdd BLAST21
Topological domaini258 – 270ExtracellularSequence analysisAdd BLAST13
Transmembranei271 – 276Helical; Name=7Sequence analysis6

Keywords - Cellular componenti

Cell membrane, Membrane

Pathology & Biotechi

Polymorphism and mutation databases

DMDMi38372790

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001507101 – 276Putative olfactory receptor 10J6Add BLAST276

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi5N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi97 ↔ 188PROSITE-ProRule annotation
Glycosylationi190N-linked (GlcNAc...) asparagineSequence analysis1

Keywords - PTMi

Disulfide bond, Glycoprotein

Proteomic databases

PRIDEiQ8NGY7
ProteomicsDBi73627

Structurei

3D structure databases

ProteinModelPortaliQ8NGY7
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the G-protein coupled receptor 1 family.PROSITE-ProRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

HOVERGENiHBG017625
InParanoidiQ8NGY7
PhylomeDBiQ8NGY7

Family and domain databases

InterProiView protein in InterPro
IPR000276 GPCR_Rhodpsn
IPR017452 GPCR_Rhodpsn_7TM
IPR000725 Olfact_rcpt
PfamiView protein in Pfam
PF13853 7tm_4, 1 hit
PRINTSiPR00237 GPCRRHODOPSN
PR00245 OLFACTORYR
PROSITEiView protein in PROSITE
PS50262 G_PROTEIN_RECEP_F1_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q8NGY7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MRRKNLTEVT EFVFLGFSRF HKHHITLFVV FLILYTLTVA GNAIIMTIIC
60 70 80 90 100
IDRHLHTPMY FFLSMLASSK TVYTLFIIPQ MLSSFVTQTQ PISLAGCTTQ
110 120 130 140 150
TFFFVTLAIN NCFLLTVMGY DHYMAICNPL RYRVITSKKV CVQLVCGAFS
160 170 180 190 200
IGLAMAAVQV TSIFTLPFCH TVVGHFFCDI LPVMKLSCIN TTINEIINFV
210 220 230 240 250
VRLFVILVPM GLVFISYVLI ISTVLKIASA EGWKKTFATC AFHLTVVIVH
260 270
YGCASIAYLM PKSENSIEQD LLLSVT
Length:276
Mass (Da):31,021
Last modified:October 1, 2002 - v1
Checksum:iB2B9A88B8FBA1126
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB065629 Genomic DNA Translation: BAC05855.1
AF399588 Genomic DNA Translation: AAK95073.1

Similar proteinsi

Cross-referencesi

Web resourcesi

Human Olfactory Receptor Data Exploratorium (HORDE)

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB065629 Genomic DNA Translation: BAC05855.1
AF399588 Genomic DNA Translation: AAK95073.1

3D structure databases

ProteinModelPortaliQ8NGY7
ModBaseiSearch...
MobiDBiSearch...

Protein family/group databases

GPCRDBiSearch...

Polymorphism and mutation databases

DMDMi38372790

Proteomic databases

PRIDEiQ8NGY7
ProteomicsDBi73627

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Organism-specific databases

GeneCardsiOR10J6P
HGNCiHGNC:14994 OR10J6P
neXtProtiNX_Q8NGY7
GenAtlasiSearch...

Phylogenomic databases

HOVERGENiHBG017625
InParanoidiQ8NGY7
PhylomeDBiQ8NGY7

Enzyme and pathway databases

ReactomeiR-HSA-381753 Olfactory Signaling Pathway

Family and domain databases

InterProiView protein in InterPro
IPR000276 GPCR_Rhodpsn
IPR017452 GPCR_Rhodpsn_7TM
IPR000725 Olfact_rcpt
PfamiView protein in Pfam
PF13853 7tm_4, 1 hit
PRINTSiPR00237 GPCRRHODOPSN
PR00245 OLFACTORYR
PROSITEiView protein in PROSITE
PS50262 G_PROTEIN_RECEP_F1_2, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiO10J6_HUMAN
AccessioniPrimary (citable) accession number: Q8NGY7
Secondary accession number(s): Q96R55
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 10, 2003
Last sequence update: October 1, 2002
Last modified: November 7, 2018
This is version 94 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Human chromosome 1
    Human chromosome 1: entries, gene names and cross-references to MIM
  3. 7-transmembrane G-linked receptors
    List of 7-transmembrane G-linked receptor entries
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