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Protein

Putative olfactory receptor 9A1

Gene

OR9A1P

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: -Protein uncertaini

Functioni

Odorant receptor.Curated

Caution

Could be the product of a pseudogene. Much shorter than related proteins.Curated

GO - Molecular functioni

Keywordsi

Molecular functionG-protein coupled receptor, Receptor, Transducer
Biological processOlfaction, Sensory transduction

Enzyme and pathway databases

ReactomeiR-HSA-381753 Olfactory Signaling Pathway

Names & Taxonomyi

Protein namesi
Recommended name:
Putative olfactory receptor 9A1
Alternative name(s):
HSHTPRX06
Gene namesi
Name:OR9A1P
Synonyms:OR9A1
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Unplaced

Organism-specific databases

HGNCiHGNC:8486 OR9A1P
neXtProtiNX_Q8NGU1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 24ExtracellularSequence analysisAdd BLAST24
Transmembranei25 – 45Helical; Name=1Sequence analysisAdd BLAST21
Topological domaini46 – 64CytoplasmicSequence analysisAdd BLAST19
Transmembranei65 – 85Helical; Name=2Sequence analysisAdd BLAST21
Topological domaini86 – 99ExtracellularSequence analysisAdd BLAST14
Transmembranei100 – 120Helical; Name=3Sequence analysisAdd BLAST21
Topological domaini121 – 140CytoplasmicSequence analysisAdd BLAST20
Transmembranei141 – 161Helical; Name=4Sequence analysisAdd BLAST21
Topological domaini162 – 196ExtracellularSequence analysisAdd BLAST35
Transmembranei197 – 217Helical; Name=5Sequence analysisAdd BLAST21
Topological domaini218 – 239CytoplasmicSequence analysisAdd BLAST22
Transmembranei240 – 260Helical; Name=6Sequence analysisAdd BLAST21
Topological domaini261 – 263ExtracellularSequence analysis3

Keywords - Cellular componenti

Cell membrane, Membrane

Pathology & Biotechi

Polymorphism and mutation databases

DMDMi206558310

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003454171 – 263Putative olfactory receptor 9A1Add BLAST263

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi97 ↔ 179PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bond

Proteomic databases

PRIDEiQ8NGU1
ProteomicsDBi73603

Structurei

3D structure databases

ProteinModelPortaliQ8NGU1
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the G-protein coupled receptor 1 family.PROSITE-ProRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

HOVERGENiHBG017625
InParanoidiQ8NGU1
PhylomeDBiQ8NGU1

Family and domain databases

InterProiView protein in InterPro
IPR000276 GPCR_Rhodpsn
IPR017452 GPCR_Rhodpsn_7TM
IPR000725 Olfact_rcpt
PfamiView protein in Pfam
PF13853 7tm_4, 1 hit
PRINTSiPR00237 GPCRRHODOPSN
PR00245 OLFACTORYR
PROSITEiView protein in PROSITE
PS00237 G_PROTEIN_RECEP_F1_1, 1 hit
PS50262 G_PROTEIN_RECEP_F1_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q8NGU1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLGNYSSATE FFLLGFPGSQ EVCRILFATF FLLYAVTVMG NVVIIITVCV
60 70 80 90 100
DKCLQSPIYF FLGHLCVLEI LITSTAVPFM LWGLLLPSTQ IMSLTACAAQ
110 120 130 140 150
LYLYLSLGTL ELALMGVMAV DRYVAVCNPL RYNIIMNSST FIWVIIVSWV
160 170 180 190 200
LGFLSEIWPV YATFQLTFCK SSVLDHFYCD RGQLLKVSCE DTLFREFILF
210 220 230 240 250
LMAVFIIIGS LIPTIVSYTY IISTNLKIPS ASGWRKSFST CASHFTYVVI
260
GYGSCLFLYV KPK
Length:263
Mass (Da):29,546
Last modified:July 22, 2008 - v2
Checksum:iB6BF8FCACC5B2E87
GO

Sequence cautioni

The sequence BAC05913 differs from that shown. Reason: Erroneous initiation.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB065690 Genomic DNA Translation: BAC05913.1 Different initiation.
X64982 mRNA No translation available.
UniGeneiHs.544835

Similar proteinsi

Entry informationi

Entry nameiOR9A1_HUMAN
AccessioniPrimary (citable) accession number: Q8NGU1
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 22, 2008
Last sequence update: July 22, 2008
Last modified: June 20, 2018
This is version 90 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. 7-transmembrane G-linked receptors
    List of 7-transmembrane G-linked receptor entries
  2. Human chromosome 7
    Human chromosome 7: entries, gene names and cross-references to MIM
  3. SIMILARITY comments
    Index of protein domains and families

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