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Protein

Olfactory receptor 13C9

Gene

OR13C9

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Odorant receptor.Curated

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionG-protein coupled receptor, Receptor, Transducer
Biological processOlfaction, Sensory transduction

Enzyme and pathway databases

ReactomeiR-HSA-381753 Olfactory Signaling Pathway

Names & Taxonomyi

Protein namesi
Recommended name:
Olfactory receptor 13C9
Alternative name(s):
Olfactory receptor OR9-13
Gene namesi
Name:OR13C9
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 9

Organism-specific databases

EuPathDBiHostDB:ENSG00000136839.1
HGNCiHGNC:15104 OR13C9
neXtProtiNX_Q8NGT0

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 25ExtracellularSequence analysisAdd BLAST25
Transmembranei26 – 46Helical; Name=1Sequence analysisAdd BLAST21
Topological domaini47 – 54CytoplasmicSequence analysis8
Transmembranei55 – 75Helical; Name=2Sequence analysisAdd BLAST21
Topological domaini76 – 99ExtracellularSequence analysisAdd BLAST24
Transmembranei100 – 120Helical; Name=3Sequence analysisAdd BLAST21
Topological domaini121 – 139CytoplasmicSequence analysisAdd BLAST19
Transmembranei140 – 160Helical; Name=4Sequence analysisAdd BLAST21
Topological domaini161 – 197ExtracellularSequence analysisAdd BLAST37
Transmembranei198 – 217Helical; Name=5Sequence analysisAdd BLAST20
Topological domaini218 – 237CytoplasmicSequence analysisAdd BLAST20
Transmembranei238 – 258Helical; Name=6Sequence analysisAdd BLAST21
Topological domaini259 – 277ExtracellularSequence analysisAdd BLAST19
Transmembranei278 – 298Helical; Name=7Sequence analysisAdd BLAST21
Topological domaini299 – 318CytoplasmicSequence analysisAdd BLAST20

Keywords - Cellular componenti

Cell membrane, Membrane

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA32039

Polymorphism and mutation databases

BioMutaiOR13C9
DMDMi38372767

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001507361 – 318Olfactory receptor 13C9Add BLAST318

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi5N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi97 ↔ 189PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bond, Glycoprotein

Proteomic databases

PaxDbiQ8NGT0
PeptideAtlasiQ8NGT0
PRIDEiQ8NGT0
ProteomicsDBi73597

Expressioni

Gene expression databases

BgeeiENSG00000136839
CleanExiHS_OR13C9

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000259362

Structurei

3D structure databases

ProteinModelPortaliQ8NGT0
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the G-protein coupled receptor 1 family.PROSITE-ProRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG410IENR Eukaryota
ENOG4111CQX LUCA
GeneTreeiENSGT00760000119058
HOGENOMiHOG000041362
HOVERGENiHBG017625
InParanoidiQ8NGT0
KOiK04257
OMAiMKMACAD
OrthoDBiEOG091G0CU6
PhylomeDBiQ8NGT0
TreeFamiTF352686

Family and domain databases

InterProiView protein in InterPro
IPR000276 GPCR_Rhodpsn
IPR017452 GPCR_Rhodpsn_7TM
IPR000725 Olfact_rcpt
PfamiView protein in Pfam
PF13853 7tm_4, 1 hit
PRINTSiPR00237 GPCRRHODOPSN
PR00245 OLFACTORYR
PROSITEiView protein in PROSITE
PS00237 G_PROTEIN_RECEP_F1_1, 1 hit
PS50262 G_PROTEIN_RECEP_F1_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q8NGT0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEWENQTILV EFFLKGHSVH PRLELLFFVL IFIMYVVILL GNGTLILISI
60 70 80 90 100
LDPHLHTPMY FFLGNLSFLD ICYTTTSIPS TLVSFLSERK TISFSGCAVQ
110 120 130 140 150
MFLGLAMGTT ECVLLGMMAF DRYVAICNPL RYPIIMSKNA YVPMAVGSWF
160 170 180 190 200
AGIVNSAVQT TFVVQLPFCR KNVINHFSCE ILAVMKLACA DISGNEFLML
210 220 230 240 250
VATILFTLMP LLLIVISYSL IISSILKIHS SEGRSKAFST CSAHLTVVII
260 270 280 290 300
FYGTILFMYM KPKSKETLNS DDLDATDKII SMFYGVMTPM MNPLIYSLRN
310
KDVKEAVKHL PNRRFFSK
Length:318
Mass (Da):35,854
Last modified:October 1, 2002 - v1
Checksum:i318CA874691F8A7D
GO

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Natural variantiVAR_02413624E → D. Corresponds to variant dbSNP:rs2900373Ensembl.1
Natural variantiVAR_03430891T → S. Corresponds to variant dbSNP:rs993658Ensembl.1
Natural variantiVAR_053301197F → L. Corresponds to variant dbSNP:rs10761054Ensembl.1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB065708 Genomic DNA Translation: BAC05930.1
AL359846 Genomic DNA No translation available.
CH471105 Genomic DNA Translation: EAW58988.1
BK004250 Genomic DNA Translation: DAA04648.1
CCDSiCCDS35093.1
RefSeqiNP_001001956.1, NM_001001956.1
UniGeneiHs.553682

Genome annotation databases

EnsembliENST00000259362; ENSP00000259362; ENSG00000136839
GeneIDi286362
KEGGihsa:286362
UCSCiuc011lvr.2 human

Keywords - Coding sequence diversityi

Polymorphism

Similar proteinsi

Entry informationi

Entry nameiO13C9_HUMAN
AccessioniPrimary (citable) accession number: Q8NGT0
Secondary accession number(s): Q6IFL2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 10, 2003
Last sequence update: October 1, 2002
Last modified: June 20, 2018
This is version 126 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. 7-transmembrane G-linked receptors
    List of 7-transmembrane G-linked receptor entries
  2. Human chromosome 9
    Human chromosome 9: entries, gene names and cross-references to MIM
  3. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  4. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  5. SIMILARITY comments
    Index of protein domains and families

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