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Protein

Olfactory receptor 9I1

Gene

OR9I1

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Odorant receptor.Curated

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionG-protein coupled receptor, Receptor, Transducer
Biological processOlfaction, Sensory transduction

Enzyme and pathway databases

ReactomeiR-HSA-381753 Olfactory Signaling Pathway

Names & Taxonomyi

Protein namesi
Recommended name:
Olfactory receptor 9I1
Alternative name(s):
Olfactory receptor OR11-228
Gene namesi
Name:OR9I1
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 11

Organism-specific databases

EuPathDBiHostDB:ENSG00000172377.1
HGNCiHGNC:14718 OR9I1
neXtProtiNX_Q8NGQ6

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 25ExtracellularSequence analysisAdd BLAST25
Transmembranei26 – 46Helical; Name=1Sequence analysisAdd BLAST21
Topological domaini47 – 54CytoplasmicSequence analysis8
Transmembranei55 – 75Helical; Name=2Sequence analysisAdd BLAST21
Topological domaini76 – 99ExtracellularSequence analysisAdd BLAST24
Transmembranei100 – 120Helical; Name=3Sequence analysisAdd BLAST21
Topological domaini121 – 139CytoplasmicSequence analysisAdd BLAST19
Transmembranei140 – 160Helical; Name=4Sequence analysisAdd BLAST21
Topological domaini161 – 197ExtracellularSequence analysisAdd BLAST37
Transmembranei198 – 217Helical; Name=5Sequence analysisAdd BLAST20
Topological domaini218 – 237CytoplasmicSequence analysisAdd BLAST20
Transmembranei238 – 258Helical; Name=6Sequence analysisAdd BLAST21
Topological domaini259 – 271ExtracellularSequence analysisAdd BLAST13
Transmembranei272 – 292Helical; Name=7Sequence analysisAdd BLAST21
Topological domaini293 – 314CytoplasmicSequence analysisAdd BLAST22

Keywords - Cellular componenti

Cell membrane, Membrane

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA32794

Polymorphism and mutation databases

BioMutaiOR9I1
DMDMi38372750

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001506811 – 314Olfactory receptor 9I1Add BLAST314

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi5N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi97 ↔ 189PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bond, Glycoprotein

Proteomic databases

PaxDbiQ8NGQ6
PRIDEiQ8NGQ6
ProteomicsDBi73578

PTM databases

PhosphoSitePlusiQ8NGQ6

Expressioni

Gene expression databases

BgeeiENSG00000172377
CleanExiHS_OR9I1
ExpressionAtlasiQ8NGQ6 baseline and differential

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000302606

Structurei

3D structure databases

ProteinModelPortaliQ8NGQ6
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the G-protein coupled receptor 1 family.PROSITE-ProRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG410IPDA Eukaryota
ENOG41119U6 LUCA
GeneTreeiENSGT00810000125445
HOGENOMiHOG000041364
HOVERGENiHBG017625
InParanoidiQ8NGQ6
KOiK04257
OMAiMYLQSGS
OrthoDBiEOG091G0AZH
PhylomeDBiQ8NGQ6
TreeFamiTF337111

Family and domain databases

InterProiView protein in InterPro
IPR000276 GPCR_Rhodpsn
IPR017452 GPCR_Rhodpsn_7TM
IPR000725 Olfact_rcpt
PfamiView protein in Pfam
PF13853 7tm_4, 1 hit
PRINTSiPR00237 GPCRRHODOPSN
PR00245 OLFACTORYR
PROSITEiView protein in PROSITE
PS00237 G_PROTEIN_RECEP_F1_1, 1 hit
PS50262 G_PROTEIN_RECEP_F1_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q8NGQ6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAKNNLTRVT EFILMGFMDH PKLEIPLFLV FLSFYLVTLL GNVGMIMLIQ
60 70 80 90 100
VDVKLYTPMY FFLSHLSLLD ACYTSVITPQ ILATLATGKT VISYGHCAAQ
110 120 130 140 150
FFLFTICAGT ECFLLAVMAY DRYAAIRNPL LYTVAMNPRL CWSLVVGAYV
160 170 180 190 200
CGVSGAILRT TCTFTLSFCK DNQINFFFCD LPPLLKLACS DTANIEIVII
210 220 230 240 250
FFGNFVILAN ASVILISYLL IIKTILKVKS SGGRAKTFST CASHITAVAL
260 270 280 290 300
FFGALIFMYL QSGSGKSLEE DKVVSVFYTV VIPMLNPLIY SLRNKDVKDA
310
FRKVARRLQV SLSM
Length:314
Mass (Da):34,908
Last modified:October 1, 2002 - v1
Checksum:iBCB7E6BC6ADA706A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB065733 Genomic DNA Translation: BAC05954.1
CH471076 Genomic DNA Translation: EAW73796.1
AF399531 Genomic DNA Translation: AAK95016.1
BK004292 Genomic DNA Translation: DAA04690.1
CCDSiCCDS31542.1
RefSeqiNP_001005211.1, NM_001005211.1
UniGeneiHs.632122

Genome annotation databases

EnsembliENST00000302610; ENSP00000302606; ENSG00000172377
ENST00000641439; ENSP00000493370; ENSG00000172377
ENST00000641478; ENSP00000493104; ENSG00000172377
GeneIDi219954
KEGGihsa:219954
UCSCiuc001nml.1 human

Similar proteinsi

Entry informationi

Entry nameiOR9I1_HUMAN
AccessioniPrimary (citable) accession number: Q8NGQ6
Secondary accession number(s): Q6IFH0, Q96RA8
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 10, 2003
Last sequence update: October 1, 2002
Last modified: June 20, 2018
This is version 131 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. 7-transmembrane G-linked receptors
    List of 7-transmembrane G-linked receptor entries
  2. Human chromosome 11
    Human chromosome 11: entries, gene names and cross-references to MIM
  3. SIMILARITY comments
    Index of protein domains and families

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