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Protein

Neurobeachin

Gene

NBEA

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Binds to type II regulatory subunits of protein kinase A and anchors/targets them to the membrane. May anchor the kinase to cytoskeletal and/or organelle-associated proteins (By similarity).By similarity

GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

SignaLinkiQ8NFP9

Names & Taxonomyi

Protein namesi
Recommended name:
Neurobeachin
Alternative name(s):
Lysosomal-trafficking regulator 2
Protein BCL8B
Gene namesi
Name:NBEA
Synonyms:BCL8B, KIAA1544, LYST2
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 13

Organism-specific databases

EuPathDBiHostDB:ENSG00000172915.18
HGNCiHGNC:7648 NBEA
MIMi604889 gene
neXtProtiNX_Q8NFP9

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Membrane

Pathology & Biotechi

Organism-specific databases

DisGeNETi26960
OpenTargetsiENSG00000172915
PharmGKBiPA31454

Polymorphism and mutation databases

BioMutaiNBEA
DMDMi296439289

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000510891 – 2946NeurobeachinAdd BLAST2946

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei1011PhosphoserineBy similarity1
Modified residuei1014PhosphoserineBy similarity1
Modified residuei1529PhosphoserineBy similarity1
Modified residuei1714PhosphoserineBy similarity1
Modified residuei1717PhosphoserineBy similarity1
Modified residuei2138PhosphoserineBy similarity1
Modified residuei2575PhosphoserineBy similarity1

Keywords - PTMi

Phosphoprotein

Proteomic databases

EPDiQ8NFP9
MaxQBiQ8NFP9
PaxDbiQ8NFP9
PeptideAtlasiQ8NFP9
PRIDEiQ8NFP9
ProteomicsDBi73333
73334 [Q8NFP9-2]

PTM databases

iPTMnetiQ8NFP9
PhosphoSitePlusiQ8NFP9

Expressioni

Tissue specificityi

Predominant in many brain structures. Also expressed at medium levels in spleen, thymus, prostate, testis and ovary. Low level expression is seen in heart, kidney, pancreas, skeletal muscle and intestine.1 Publication

Gene expression databases

BgeeiENSG00000172915 Expressed in 212 organ(s), highest expression level in neocortex
CleanExiHS_NBEA
ExpressionAtlasiQ8NFP9 baseline and differential
GenevisibleiQ8NFP9 HS

Organism-specific databases

HPAiHPA039730
HPA040385

Interactioni

Subunit structurei

Interacts with RII subunit of PKA.By similarity

GO - Molecular functioni

Protein-protein interaction databases

BioGridi117928, 17 interactors
IntActiQ8NFP9, 12 interactors
MINTiQ8NFP9
STRINGi9606.ENSP00000383295

Structurei

Secondary structure

12946
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

ProteinModelPortaliQ8NFP9
SMRiQ8NFP9
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ8NFP9

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Repeati1326 – 1368WD 1CuratedAdd BLAST43
Domaini2147 – 2255BEACH-type PHPROSITE-ProRule annotationAdd BLAST109
Domaini2274 – 2563BEACHPROSITE-ProRule annotationCuratedAdd BLAST290
Repeati2718 – 2761WD 2CuratedAdd BLAST44
Repeati2778 – 2818WD 3CuratedAdd BLAST41
Repeati2860 – 2899WD 4CuratedAdd BLAST40
Repeati2902 – 2941WD 5CuratedAdd BLAST40

Domaini

RII-alpha binding site, predicted to form an amphipathic helix, could participate in protein-protein interactions with a complementary surface on the R-subunit dimer.By similarity

Sequence similaritiesi

Belongs to the WD repeat neurobeachin family.Curated

Keywords - Domaini

Repeat, WD repeat

Phylogenomic databases

eggNOGiKOG1786 Eukaryota
ENOG410XNQC LUCA
GeneTreeiENSGT00760000119083
HOGENOMiHOG000082375
HOVERGENiHBG012582
InParanoidiQ8NFP9
PhylomeDBiQ8NFP9
TreeFamiTF313490

Family and domain databases

CDDicd06071 Beach, 1 hit
cd01201 PH_BEACH, 1 hit
Gene3Di1.10.1540.10, 1 hit
InterProiView protein in InterPro
IPR016024 ARM-type_fold
IPR000409 BEACH_dom
IPR036372 BEACH_dom_sf
IPR013320 ConA-like_dom_sf
IPR010508 DUF1088
IPR031570 DUF4704
IPR023362 PH-BEACH_dom
IPR001680 WD40_repeat
IPR017986 WD40_repeat_dom
IPR036322 WD40_repeat_dom_sf
PfamiView protein in Pfam
PF02138 Beach, 1 hit
PF06469 DUF1088, 1 hit
PF15787 DUF4704, 1 hit
PF14844 PH_BEACH, 1 hit
SMARTiView protein in SMART
SM01026 Beach, 1 hit
SM00320 WD40, 5 hits
SUPFAMiSSF48371 SSF48371, 1 hit
SSF49899 SSF49899, 1 hit
SSF50978 SSF50978, 1 hit
SSF81837 SSF81837, 1 hit
PROSITEiView protein in PROSITE
PS50197 BEACH, 1 hit
PS51783 PH_BEACH, 1 hit
PS50294 WD_REPEATS_REGION, 1 hit

Sequences (3+)i

Sequence statusi: Complete.

This entry describes 3 isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 3 described isoforms and 3 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1Curated (identifier: Q8NFP9-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MASEKPGPGP GLEPQPVGLI AVGAAGGGGG GSGGGGTGGS GMGELRGASG
60 70 80 90 100
SGSVMLPAGM INPSVPIRNI RMKFAVLIGL IQVGEVSNRD IVETVLNLLV
110 120 130 140 150
GGEFDLEMNF IIQDAESITC MTELLEHCDV TCQAEIWSMF TAILRKSVRN
160 170 180 190 200
LQTSTEVGLI EQVLLKMSAV DDMIADLLVD MLGVLASYSI TVKELKLLFS
210 220 230 240 250
MLRGESGIWP RHAVKLLSVL NQMPQRHGPD TFFNFPGCSA AAIALPPIAK
260 270 280 290 300
WPYQNGFTLN TWFRMDPLNN INVDKDKPYL YCFRTSKGVG YSAHFVGNCL
310 320 330 340 350
IVTSLKSKGK GFQHCVKYDF QPRKWYMISI VHIYNRWRNS EIRCYVNGQL
360 370 380 390 400
VSYGDMAWHV NTNDSYDKCF LGSSETADAN RVFCGQLGAV YVFSEALNPA
410 420 430 440 450
QIFAIHQLGP GYKSTFKFKS ESDIHLAEHH KQVLYDGKLA SSIAFTYNAK
460 470 480 490 500
ATDAQLCLES SPKENASIFV HSPHALMLQD VKAIVTHSIH SAIHSIGGIQ
510 520 530 540 550
VLFPLFAQLD NRQLNDSQVE TTVCATLLAF LVELLKSSVA MQEQMLGGKG
560 570 580 590 600
FLVIGYLLEK SSRVHITRAV LEQFLSFAKY LDGLSHGAPL LKQLCDHILF
610 620 630 640 650
NPAIWIHTPA KVQLSLYTYL SAEFIGTATI YTTIRRVGTV LQLMHTLKYY
660 670 680 690 700
YWVINPADSS GITPKGLDGP RPSQKEIISL RAFMLLFLKQ LILKDRGVKE
710 720 730 740 750
DELQSILNYL LTMHEDENIH DVLQLLVALM SEHPASMIPA FDQRNGIRVI
760 770 780 790 800
YKLLASKSES IWVQALKVLG YFLKHLGHKR KVEIMHTHSL FTLLGERLML
810 820 830 840 850
HTNTVTVTTY NTLYEILTEQ VCTQVVHKPH PEPDSTVKIQ NPMILKVVAT
860 870 880 890 900
LLKNSTPSAE LMEVRRLFLS DMIKLFSNSR ENRRCLLQCS VWQDWMFSLG
910 920 930 940 950
YINPKNSEEQ KITEMVYNIF RILLYHAIKY EWGGWRVWVD TLSIAHSKVT
960 970 980 990 1000
YEAHKEYLAK MYEEYQRQEE ENIKKGKKGN VSTISGLSSQ TTGAKGGMEI
1010 1020 1030 1040 1050
REIEDLSQSQ SPESETDYPV STDTRDLLMS TKVSDDILGN SDRPGSGVHV
1060 1070 1080 1090 1100
EVHDLLVDIK AEKVEATEVK LDDMDLSPET LVGGENGALV EVESLLDNVY
1110 1120 1130 1140 1150
SAAVEKLQNN VHGSVGIIKK NEEKDNGPLI TLADEKEDLP NSSTSFLFDK
1160 1170 1180 1190 1200
IPKQEEKLLP ELSSNHIIPN IQDTQVHLGV SDDLGLLAHM TGSVDLTCTS
1210 1220 1230 1240 1250
SIIEEKEFKI HTTSDGMSSI SERDLASSTK GLEYAEMTAT TLETESSSSK
1260 1270 1280 1290 1300
IVPNIDAGSI ISDTERSDDG KESGKEIRKI QTTTTTQAVQ GRSITQQDRD
1310 1320 1330 1340 1350
LRVDLGFRGM PMTEEQRRQF SPGPRTTMFR IPEFKWSPMH QRLLTDLLFA
1360 1370 1380 1390 1400
LETDVHVWRS HSTKSVMDFV NSNENIIFVH NTIHLISQMV DNIIIACGGI
1410 1420 1430 1440 1450
LPLLSAATSP TGSKTELENI EVTQGMSAET AVTFLSRLMA MVDVLVFASS
1460 1470 1480 1490 1500
LNFSEIEAEK NMSSGGLMRQ CLRLVCCVAV RNCLECRQRQ RDRGNKSSHG
1510 1520 1530 1540 1550
SSKPQEVPQS VTATAASKTP LENVPGNLSP IKDPDRLLQD VDINRLRAVV
1560 1570 1580 1590 1600
FRDVDDSKQA QFLALAVVYF ISVLMVSKYR DILEPQRETT RTGSQPGRNI
1610 1620 1630 1640 1650
RQEINSPTST VVVIPSIPHP SLNHGFLAKL IPEQSFGHSF YKETPAAFPD
1660 1670 1680 1690 1700
TIKEKETPTP GEDIQVESSI PHTDSGIGEE QVASILNGAE LETSTGPDAM
1710 1720 1730 1740 1750
SELLSTLSSE VKKSQESLTE NPSETLKPAT SISSISQTKG INVKEILKSL
1760 1770 1780 1790 1800
VAAPVEIAEC GPEPIPYPDP ALKRETQAIL PMQFHSFDRS VVVPVKKPPP
1810 1820 1830 1840 1850
GSLAVTTVGA TTAGSGLPTG STSNIFAATG ATPKSMINTT GAVDSGSSSS
1860 1870 1880 1890 1900
SSSSSFVNGA TSKNLPAVQT VAPMPEDSAE NMSITAKLER ALEKVAPLLR
1910 1920 1930 1940 1950
EIFVDFAPFL SRTLLGSHGQ ELLIEGLVCM KSSTSVVELV MLLCSQEWQN
1960 1970 1980 1990 2000
SIQKNAGLAF IELINEGRLL CHAMKDHIVR VANEAEFILN RQRAEDVHKH
2010 2020 2030 2040 2050
AEFESQCAQY AADRREEEKM CDHLISAAKH RDHVTANQLK QKILNILTNK
2060 2070 2080 2090 2100
HGAWGAVSHS QLHDFWRLDY WEDDLRRRRR FVRNAFGSTH AEALLKAAIE
2110 2120 2130 2140 2150
YGTEEDVVKS KKTFRSQAIV NQNAETELML EGDDDAVSLL QEKEIDNLAG
2160 2170 2180 2190 2200
PVVLSTPAQL IAPVVVAKGT LSITTTEIYF EVDEDDSAFK KIDTKVLAYT
2210 2220 2230 2240 2250
EGLHGKWMFS EIRAVFSRRY LLQNTALEVF MANRTSVMFN FPDQATVKKV
2260 2270 2280 2290 2300
VYSLPRVGVG TSYGLPQARR ISLATPRQLY KSSNMTQRWQ RREISNFEYL
2310 2320 2330 2340 2350
MFLNTIAGRT YNDLNQYPVF PWVLTNYESE ELDLTLPGNF RDLSKPIGAL
2360 2370 2380 2390 2400
NPKRAVFYAE RYETWEDDQS PPYHYNTHYS TATSTLSWLV RIEPFTTFFL
2410 2420 2430 2440 2450
NANDGKFDHP DRTFSSVARS WRTSQRDTSD VKELIPEFYY LPEMFVNSNG
2460 2470 2480 2490 2500
YNLGVREDEV VVNDVDLPPW AKKPEDFVRI NRMALESEFV SCQLHQWIDL
2510 2520 2530 2540 2550
IFGYKQRGPE AVRALNVFHY LTYEGSVNLD SITDPVLREA MEAQIQNFGQ
2560 2570 2580 2590 2600
TPSQLLIEPH PPRSSAMHLC FLPQSPLMFK DQMQQDVIMV LKFPSNSPVT
2610 2620 2630 2640 2650
HVAANTLPHL TIPAVVTVTC SRLFAVNRWH NTVGLRGAPG YSLDQAHHLP
2660 2670 2680 2690 2700
IEMDPLIANN SGVNKRQITD LVDQSIQINA HCFVVTADNR YILICGFWDK
2710 2720 2730 2740 2750
SFRVYSTETG KLTQIVFGHW DVVTCLARSE SYIGGDCYIV SGSRDATLLL
2760 2770 2780 2790 2800
WYWSGRHHII GDNPNSSDYP APRAVLTGHD HEVVCVSVCA ELGLVISGAK
2810 2820 2830 2840 2850
EGPCLVHTIT GDLLRALEGP ENCLFPRLIS VSSEGHCIIY YERGRFSNFS
2860 2870 2880 2890 2900
INGKLLAQME INDSTRAILL SSDGQNLVTG GDNGVVEVWQ ACDFKQLYIY
2910 2920 2930 2940
PGCDAGIRAM DLSHDQRTLI TGMASGSIVA FNIDFNRWHY EHQNRY
Length:2,946
Mass (Da):327,822
Last modified:May 18, 2010 - v3
Checksum:i2E371FDA2F00781E
GO
Isoform 2Curated (identifier: Q8NFP9-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-2443: Missing.
     2539-2539: E → EIPEAYFIRDPHTFLLTKDFIK

Note: No experimental confirmation available.Curated
Show »
Length:524
Mass (Da):58,802
Checksum:iF4A38C3EFE58D390
GO
Isoform 3 (identifier: Q8NFP9-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-2207: Missing.

Note: No experimental confirmation available.
Show »
Length:739
Mass (Da):84,001
Checksum:i38BA7126B5FFBBE7
GO

Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q5T321Q5T321_HUMAN
Neurobeachin, isoform CRA_e
NBEA hCG_2019985
2,943Annotation score:
F5GXV7F5GXV7_HUMAN
Neurobeachin
NBEA
2,947Annotation score:
A0A0D9SF28A0A0D9SF28_HUMAN
Neurobeachin
NBEA
2,946Annotation score:

Sequence cautioni

The sequence AAD41633 differs from that shown. Reason: Frameshift at position 2900.Curated
The sequence BAA91485 differs from that shown. Reason: Erroneous termination at position 762. Translated as Trp.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti1658P → S in AAM53531 (PubMed:12160729).Curated1
Sequence conflicti2564S → N in AAD41633 (Ref. 6) Curated1
Sequence conflicti2706S → T in AAD41633 (Ref. 6) Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Natural variantiVAR_047658569A → P. Corresponds to variant dbSNP:rs5011295Ensembl.1
Natural variantiVAR_0476592501I → V. Corresponds to variant dbSNP:rs11538677Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Alternative sequenceiVSP_0505381 – 2443Missing in isoform 2. 1 PublicationAdd BLAST2443
Alternative sequenceiVSP_0463971 – 2207Missing in isoform 3. 1 PublicationAdd BLAST2207
Alternative sequenceiVSP_0505392539E → EIPEAYFIRDPHTFLLTKDF IK in isoform 2. 1 Publication1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF467288 mRNA Translation: AAM53531.1
AL138690 Genomic DNA No translation available.
AK001059 mRNA Translation: BAA91485.1 Sequence problems.
AK294737 mRNA Translation: BAH11865.1
AL139083, AL390071 Genomic DNA Translation: CAH71883.1
AL159160 Genomic DNA No translation available.
AL161718 Genomic DNA No translation available.
AL161902 Genomic DNA No translation available.
AL356430 Genomic DNA No translation available.
AL357083 Genomic DNA No translation available.
AL390071, AL139083 Genomic DNA Translation: CAI17183.1
AB046764 mRNA Translation: BAB13370.1
AL137748 mRNA Translation: CAB70903.2
AF072371 mRNA Translation: AAD41633.1 Frameshift.
CCDSiCCDS45026.1 [Q8NFP9-1]
CCDS55894.1 [Q8NFP9-3]
PIRiT46310
RefSeqiNP_001191126.1, NM_001204197.1 [Q8NFP9-3]
NP_056493.3, NM_015678.4 [Q8NFP9-1]
UniGeneiHs.491172

Genome annotation databases

EnsembliENST00000379922; ENSP00000369254; ENSG00000172915 [Q8NFP9-2]
ENST00000400445; ENSP00000383295; ENSG00000172915 [Q8NFP9-1]
ENST00000537702; ENSP00000440233; ENSG00000172915 [Q8NFP9-3]
GeneIDi26960
KEGGihsa:26960
UCSCiuc058wka.1 human [Q8NFP9-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF467288 mRNA Translation: AAM53531.1
AL138690 Genomic DNA No translation available.
AK001059 mRNA Translation: BAA91485.1 Sequence problems.
AK294737 mRNA Translation: BAH11865.1
AL139083, AL390071 Genomic DNA Translation: CAH71883.1
AL159160 Genomic DNA No translation available.
AL161718 Genomic DNA No translation available.
AL161902 Genomic DNA No translation available.
AL356430 Genomic DNA No translation available.
AL357083 Genomic DNA No translation available.
AL390071, AL139083 Genomic DNA Translation: CAI17183.1
AB046764 mRNA Translation: BAB13370.1
AL137748 mRNA Translation: CAB70903.2
AF072371 mRNA Translation: AAD41633.1 Frameshift.
CCDSiCCDS45026.1 [Q8NFP9-1]
CCDS55894.1 [Q8NFP9-3]
PIRiT46310
RefSeqiNP_001191126.1, NM_001204197.1 [Q8NFP9-3]
NP_056493.3, NM_015678.4 [Q8NFP9-1]
UniGeneiHs.491172

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1MI1X-ray2.90A/B2150-2563[»]
ProteinModelPortaliQ8NFP9
SMRiQ8NFP9
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi117928, 17 interactors
IntActiQ8NFP9, 12 interactors
MINTiQ8NFP9
STRINGi9606.ENSP00000383295

PTM databases

iPTMnetiQ8NFP9
PhosphoSitePlusiQ8NFP9

Polymorphism and mutation databases

BioMutaiNBEA
DMDMi296439289

Proteomic databases

EPDiQ8NFP9
MaxQBiQ8NFP9
PaxDbiQ8NFP9
PeptideAtlasiQ8NFP9
PRIDEiQ8NFP9
ProteomicsDBi73333
73334 [Q8NFP9-2]

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000379922; ENSP00000369254; ENSG00000172915 [Q8NFP9-2]
ENST00000400445; ENSP00000383295; ENSG00000172915 [Q8NFP9-1]
ENST00000537702; ENSP00000440233; ENSG00000172915 [Q8NFP9-3]
GeneIDi26960
KEGGihsa:26960
UCSCiuc058wka.1 human [Q8NFP9-1]

Organism-specific databases

CTDi26960
DisGeNETi26960
EuPathDBiHostDB:ENSG00000172915.18
GeneCardsiNBEA
H-InvDBiHIX0029795
HGNCiHGNC:7648 NBEA
HPAiHPA039730
HPA040385
MIMi604889 gene
neXtProtiNX_Q8NFP9
OpenTargetsiENSG00000172915
PharmGKBiPA31454
HUGEiSearch...
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG1786 Eukaryota
ENOG410XNQC LUCA
GeneTreeiENSGT00760000119083
HOGENOMiHOG000082375
HOVERGENiHBG012582
InParanoidiQ8NFP9
PhylomeDBiQ8NFP9
TreeFamiTF313490

Enzyme and pathway databases

SignaLinkiQ8NFP9

Miscellaneous databases

ChiTaRSiNBEA human
EvolutionaryTraceiQ8NFP9
GenomeRNAii26960
PROiPR:Q8NFP9
SOURCEiSearch...

Gene expression databases

BgeeiENSG00000172915 Expressed in 212 organ(s), highest expression level in neocortex
CleanExiHS_NBEA
ExpressionAtlasiQ8NFP9 baseline and differential
GenevisibleiQ8NFP9 HS

Family and domain databases

CDDicd06071 Beach, 1 hit
cd01201 PH_BEACH, 1 hit
Gene3Di1.10.1540.10, 1 hit
InterProiView protein in InterPro
IPR016024 ARM-type_fold
IPR000409 BEACH_dom
IPR036372 BEACH_dom_sf
IPR013320 ConA-like_dom_sf
IPR010508 DUF1088
IPR031570 DUF4704
IPR023362 PH-BEACH_dom
IPR001680 WD40_repeat
IPR017986 WD40_repeat_dom
IPR036322 WD40_repeat_dom_sf
PfamiView protein in Pfam
PF02138 Beach, 1 hit
PF06469 DUF1088, 1 hit
PF15787 DUF4704, 1 hit
PF14844 PH_BEACH, 1 hit
SMARTiView protein in SMART
SM01026 Beach, 1 hit
SM00320 WD40, 5 hits
SUPFAMiSSF48371 SSF48371, 1 hit
SSF49899 SSF49899, 1 hit
SSF50978 SSF50978, 1 hit
SSF81837 SSF81837, 1 hit
PROSITEiView protein in PROSITE
PS50197 BEACH, 1 hit
PS51783 PH_BEACH, 1 hit
PS50294 WD_REPEATS_REGION, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiNBEA_HUMAN
AccessioniPrimary (citable) accession number: Q8NFP9
Secondary accession number(s): B7Z2H9
, Q5T320, Q9HCM8, Q9NSU1, Q9NW98, Q9Y6J1
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 20, 2003
Last sequence update: May 18, 2010
Last modified: November 7, 2018
This is version 164 of the entry and version 3 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  5. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  6. Human chromosome 13
    Human chromosome 13: entries, gene names and cross-references to MIM
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