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Entry version 120 (13 Feb 2019)
Sequence version 2 (18 May 2010)
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Protein

Probable G-protein coupled receptor 156

Gene

GPR156

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Orphan receptor.

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

  • G protein-coupled GABA receptor activity Source: GO_Central

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionG-protein coupled receptor, Receptor, Transducer

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Probable G-protein coupled receptor 156
Alternative name(s):
G-protein coupled receptor PGR28
GABAB-related G-protein coupled receptor
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:GPR156
Synonyms:GABABL, PGR28
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 3

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000175697.10

Human Gene Nomenclature Database

More...
HGNCi
HGNC:20844 GPR156

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
610464 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q8NFN8

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini1 – 47ExtracellularSequence analysisAdd BLAST47
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei48 – 68HelicalSequence analysisAdd BLAST21
Topological domaini69 – 86CytoplasmicSequence analysisAdd BLAST18
Transmembranei87 – 107HelicalSequence analysisAdd BLAST21
Topological domaini108 – 118ExtracellularSequence analysisAdd BLAST11
Transmembranei119 – 139HelicalSequence analysisAdd BLAST21
Topological domaini140 – 164CytoplasmicSequence analysisAdd BLAST25
Transmembranei165 – 185HelicalSequence analysisAdd BLAST21
Topological domaini186 – 222ExtracellularSequence analysisAdd BLAST37
Transmembranei223 – 243HelicalSequence analysisAdd BLAST21
Topological domaini244 – 257CytoplasmicSequence analysisAdd BLAST14
Transmembranei258 – 278HelicalSequence analysisAdd BLAST21
Topological domaini279 – 288ExtracellularSequence analysis10
Transmembranei289 – 309HelicalSequence analysisAdd BLAST21
Topological domaini310 – 814CytoplasmicSequence analysisAdd BLAST505

Keywords - Cellular componenti

Cell membrane, Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
165829

Open Targets

More...
OpenTargetsi
ENSG00000175697

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA134918005

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
GPR156

Domain mapping of disease mutations (DMDM)

More...
DMDMi
296434518

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002068991 – 814Probable G-protein coupled receptor 156Add BLAST814

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi6N-linked (GlcNAc...) asparagineSequence analysis1

Keywords - PTMi

Glycoprotein

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q8NFN8

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q8NFN8

PeptideAtlas

More...
PeptideAtlasi
Q8NFN8

PRoteomics IDEntifications database

More...
PRIDEi
Q8NFN8

ProteomicsDB human proteome resource

More...
ProteomicsDBi
73328

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q8NFN8

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q8NFN8

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Ubiquitous expression both in the CNS and in peripheral tissues. Very high expression in fetal brain and testis relative to expression in other tissues.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000175697 Expressed in 99 organ(s), highest expression level in quadriceps femoris

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q8NFN8 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q8NFN8 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA028642
HPA028644

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
127920, 70 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000324553

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

More...
ProteinModelPortali
Q8NFN8

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili354 – 390Sequence analysisAdd BLAST37

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi600 – 603Poly-Arg4
Compositional biasi748 – 751Poly-Ser4

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Keywords - Domaini

Coiled coil, Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1055 Eukaryota
ENOG410XNN1 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000159755

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000168413

The HOVERGEN Database of Homologous Vertebrate Genes

More...
HOVERGENi
HBG081567

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q8NFN8

KEGG Orthology (KO)

More...
KOi
K04617

Identification of Orthologs from Complete Genome Data

More...
OMAi
CHRPYCE

Database of Orthologous Groups

More...
OrthoDBi
336447at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q8NFN8

TreeFam database of animal gene trees

More...
TreeFami
TF313965

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR002455 GPCR3_GABA-B
IPR017978 GPCR_3_C

The PANTHER Classification System

More...
PANTHERi
PTHR10519 PTHR10519, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00003 7tm_3, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50259 G_PROTEIN_RECEP_F3_4, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 1 potential isoform that is computationally mapped.Show allAlign All

Isoform 1 (identifier: Q8NFN8-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MEPEINCSEL CDSFPGQELD RRPLHDLCKT TITSSHHSSK TISSLSPVLL
60 70 80 90 100
GIVWTFLSCG LLLILFFLAF TIHCRKNRIV KMSSPNLNIV TLLGSCLTYS
110 120 130 140 150
SAYLFGIQDV LVGSSMETLI QTRLSMLCIG TSLVFGPILG KSWRLYKVFT
160 170 180 190 200
QRVPDKRVII KDLQLLGLVA ALLMADVILL MTWVLTDPIQ CLQILSVSMT
210 220 230 240 250
VTGKDVSCTS TSTHFCASRY SDVWIALIWG CKGLLLLYGA YLAGLTGHVS
260 270 280 290 300
SPPVNQSLTI MVGVNLLVLA AGLLFVVTRY LHSWPNLVFG LTSGGIFVCT
310 320 330 340 350
TTINCFIFIP QLKQWKAFEE ENQTIRRMAK YFSTPNKSFH TQYGEEENCH
360 370 380 390 400
PRGEKSSMER LLTEKNAVIE SLQEQVNNAK EKIVRLMSAE CTYDLPEGAA
410 420 430 440 450
PPASSPNKDV QAVASVHTLA AAQGPSGHLS DFQNDPGMAA RDSQCTSGPS
460 470 480 490 500
SYAQSLEGPG KDSSFSPGKE EKISDSKDFS DHLDSGCSQK PWTEQSLGPE
510 520 530 540 550
RGDQVPMNPS QSLLPERGGS DPQRQRHLEN SEEPPERRSR VSSVIREKLQ
560 570 580 590 600
EVLQDLGLGP EASLSTAPSC HQQTWKNSAA FSPQKMPLSK ELGFSPYMVR
610 620 630 640 650
RRRAAQRARS HFPGSAPSSV GHRANRTVPG AHSRLHVQNG DSPSLAPQTT
660 670 680 690 700
DSRVRRPSSR KPSLPSDPQD RPGTLEGSKQ SQTEPEGARG SKAAFLRQPS
710 720 730 740 750
GSGRAPSPAA PCLSKASPDL PEQWQLWPPV PSGCASLSSQ HSYFDTESSS
760 770 780 790 800
SDEFFCRCHR PYCEICFQSS SDSSDSGTSD TDPEPTGGLA SWEKLWARSK
810
PIVNFKDDLK PTLV
Length:814
Mass (Da):89,097
Last modified:May 18, 2010 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i496B0654A26B4ADB
GO
Isoform 2 (identifier: Q8NFN8-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     197-200: Missing.

Note: No experimental confirmation available.
Show »
Length:810
Mass (Da):88,679
Checksum:iCB7A2A4E901E04D3
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
F8WAW3F8WAW3_HUMAN
Probable G-protein-coupled receptor...
GPR156
78Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_049284516E → D2 PublicationsCorresponds to variant dbSNP:rs902790Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_044603197 – 200Missing in isoform 2. 1 Publication4

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AF488739 mRNA Translation: AAN03795.1
AC063952 Genomic DNA No translation available.
AC092897 Genomic DNA No translation available.
BC113701 mRNA Translation: AAI13702.1
BC143606 mRNA Translation: AAI43607.1
AY255565 mRNA Translation: AAO85077.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS2997.1 [Q8NFN8-1]
CCDS54629.1 [Q8NFN8-2]

NCBI Reference Sequences

More...
RefSeqi
NP_001161743.1, NM_001168271.1 [Q8NFN8-2]
NP_694547.2, NM_153002.2 [Q8NFN8-1]
XP_005247222.1, XM_005247165.2 [Q8NFN8-1]
XP_016861284.1, XM_017005795.1 [Q8NFN8-1]
XP_016861285.1, XM_017005796.1 [Q8NFN8-1]
XP_016861286.1, XM_017005797.1 [Q8NFN8-2]

UniGene gene-oriented nucleotide sequence clusters

More...
UniGenei
Hs.333358

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000315843; ENSP00000324553; ENSG00000175697 [Q8NFN8-1]
ENST00000461057; ENSP00000418758; ENSG00000175697 [Q8NFN8-2]
ENST00000464295; ENSP00000417261; ENSG00000175697 [Q8NFN8-1]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
165829

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:165829

UCSC genome browser

More...
UCSCi
uc011bjf.3 human [Q8NFN8-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF488739 mRNA Translation: AAN03795.1
AC063952 Genomic DNA No translation available.
AC092897 Genomic DNA No translation available.
BC113701 mRNA Translation: AAI13702.1
BC143606 mRNA Translation: AAI43607.1
AY255565 mRNA Translation: AAO85077.1
CCDSiCCDS2997.1 [Q8NFN8-1]
CCDS54629.1 [Q8NFN8-2]
RefSeqiNP_001161743.1, NM_001168271.1 [Q8NFN8-2]
NP_694547.2, NM_153002.2 [Q8NFN8-1]
XP_005247222.1, XM_005247165.2 [Q8NFN8-1]
XP_016861284.1, XM_017005795.1 [Q8NFN8-1]
XP_016861285.1, XM_017005796.1 [Q8NFN8-1]
XP_016861286.1, XM_017005797.1 [Q8NFN8-2]
UniGeneiHs.333358

3D structure databases

ProteinModelPortaliQ8NFN8
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi127920, 70 interactors
STRINGi9606.ENSP00000324553

Protein family/group databases

Information system for G protein-coupled receptors (GPCRs)

More...
GPCRDBi
Search...

PTM databases

iPTMnetiQ8NFN8
PhosphoSitePlusiQ8NFN8

Polymorphism and mutation databases

BioMutaiGPR156
DMDMi296434518

Proteomic databases

jPOSTiQ8NFN8
PaxDbiQ8NFN8
PeptideAtlasiQ8NFN8
PRIDEiQ8NFN8
ProteomicsDBi73328

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
165829
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000315843; ENSP00000324553; ENSG00000175697 [Q8NFN8-1]
ENST00000461057; ENSP00000418758; ENSG00000175697 [Q8NFN8-2]
ENST00000464295; ENSP00000417261; ENSG00000175697 [Q8NFN8-1]
GeneIDi165829
KEGGihsa:165829
UCSCiuc011bjf.3 human [Q8NFN8-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
165829
DisGeNETi165829
EuPathDBiHostDB:ENSG00000175697.10

GeneCards: human genes, protein and diseases

More...
GeneCardsi
GPR156
HGNCiHGNC:20844 GPR156
HPAiHPA028642
HPA028644
MIMi610464 gene
neXtProtiNX_Q8NFN8
OpenTargetsiENSG00000175697
PharmGKBiPA134918005

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG1055 Eukaryota
ENOG410XNN1 LUCA
GeneTreeiENSGT00940000159755
HOGENOMiHOG000168413
HOVERGENiHBG081567
InParanoidiQ8NFN8
KOiK04617
OMAiCHRPYCE
OrthoDBi336447at2759
PhylomeDBiQ8NFN8
TreeFamiTF313965

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
GPR156 human

The Gene Wiki collection of pages on human genes and proteins

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GeneWikii
GPR156

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

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GenomeRNAii
165829

Protein Ontology

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PROi
PR:Q8NFN8

The Stanford Online Universal Resource for Clones and ESTs

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SOURCEi
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Gene expression databases

BgeeiENSG00000175697 Expressed in 99 organ(s), highest expression level in quadriceps femoris
ExpressionAtlasiQ8NFN8 baseline and differential
GenevisibleiQ8NFN8 HS

Family and domain databases

InterProiView protein in InterPro
IPR002455 GPCR3_GABA-B
IPR017978 GPCR_3_C
PANTHERiPTHR10519 PTHR10519, 1 hit
PfamiView protein in Pfam
PF00003 7tm_3, 1 hit
PROSITEiView protein in PROSITE
PS50259 G_PROTEIN_RECEP_F3_4, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiGP156_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q8NFN8
Secondary accession number(s): B7ZL66
, E9PFZ4, Q14CM1, Q86SN6
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 16, 2005
Last sequence update: May 18, 2010
Last modified: February 13, 2019
This is version 120 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Human chromosome 3
    Human chromosome 3: entries, gene names and cross-references to MIM
  3. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  4. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  5. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  6. 7-transmembrane G-linked receptors
    List of 7-transmembrane G-linked receptor entries
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