Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Retrotransposon Gag-like protein 9

Gene

RTL9

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Miscellaneous

RTL9 is one of at least 11 genes called Mar or Mart related to long terminal repeat retrotransposons. They do not correspond to functional retrotransposons, but rather to neofunctionalized retrotransposons genes.1 Publication

Names & Taxonomyi

Protein namesi
Recommended name:
Retrotransposon Gag-like protein 9Imported
Alternative name(s):
Retrotransposon gag domain-containing protein 1
Tumor antigen BJ-HCC-23
Gene namesi
Name:RTL9Imported
Synonyms:KIAA1318, RGAG1
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome X

Organism-specific databases

EuPathDBiHostDB:ENSG00000243978.8
HGNCiHGNC:29245 RTL9
neXtProtiNX_Q8NET4

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000243978
PharmGKBiPA134934891

Polymorphism and mutation databases

BioMutaiRGAG1
DMDMi74715429

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002596271 – 1388Retrotransposon Gag-like protein 9Add BLAST1388

Proteomic databases

PaxDbiQ8NET4
PeptideAtlasiQ8NET4
PRIDEiQ8NET4
ProteomicsDBi73213

PTM databases

iPTMnetiQ8NET4
PhosphoSitePlusiQ8NET4

Expressioni

Gene expression databases

BgeeiENSG00000243978 Expressed in 42 organ(s), highest expression level in testis
CleanExiHS_RGAG1
ExpressionAtlasiQ8NET4 baseline and differential
GenevisibleiQ8NET4 HS

Organism-specific databases

HPAiHPA001242

Interactioni

Protein-protein interaction databases

BioGridi121588, 7 interactors
IntActiQ8NET4, 5 interactors
MINTiQ8NET4
STRINGi9606.ENSP00000419786

Structurei

3D structure databases

ProteinModelPortaliQ8NET4
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiENOG410IRCF Eukaryota
ENOG410ZEBE LUCA
GeneTreeiENSGT00730000111416
HOGENOMiHOG000231451
HOVERGENiHBG080283
InParanoidiQ8NET4
OMAiMGRIFLK
OrthoDBiEOG091G02TH
PhylomeDBiQ8NET4
TreeFamiTF334822

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

Q8NET4-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSIPLHSLRF NNTMREENVE PQNKQMAFCR PMTETRADVQ ILHSHVQLPI
60 70 80 90 100
VSTSASDPGG TSTQLMTSPV FDTMSAPLMG VPNSGALSPP LMPASDSGAL
110 120 130 140 150
SPLLMPASDS GALSPLLMPA LDSGTLSPLL STSEYGVMSP GMMTIPDFGT
160 170 180 190 200
MSATLMVAPD SAEISPLAMP APSSGVVCTP IMSTSSSEAM STPLMLAPDS
210 220 230 240 250
GELSPILMQD MNPGVMSTQP VPAPSSEAMS PLQITDEDTE AMSKVLMTAL
260 270 280 290 300
ASGEISSLLM SGTDSEAISS LIMSAVASGG TSPQPTSTQN SGGIPTPLMS
310 320 330 340 350
DLDSGIMSSL LMSSPGSEVM STPLLSVPDA GEMSTLPKPA PDAEAMSPAL
360 370 380 390 400
MTALPSGVMP TQTMPAPGSG AMSPWSTQNV DSEMMSNPPV RATASGVMSA
410 420 430 440 450
PPVRALDSGA MSTPLMGAPA SGNMSTLQKT VPASGAMTTS LMTVPSSGVM
460 470 480 490 500
STEQMSATAS RVMSAQLTMA KTSGAMPTGS MKAVAKQYKR ATASGKMSTP
510 520 530 540 550
LRRAPTSGAM STQPVTATAS ETMSMPQLTV PASGSMSMLQ MRAPVSEAMS
560 570 580 590 600
MPQMRTMASG LTSAAQMKAM TSGAMSTPLM TAQTSGSTST LLMRDTASGV
610 620 630 640 650
MSCPQMRSLA SGALSKPLMT PKASGTMFTE KMTTTASEAM PTLLMRDTVS
660 670 680 690 700
GALSMPQMTD TASGGLSASL MRDTASGAMS TSQMTATVSG GMSMPLMRAQ
710 720 730 740 750
DPGVMPASLM RAKVSGKMLS QPMSTQDPGG MSMSPMKSMT AGGMQMNSPT
760 770 780 790 800
SDVMSTPTVR AWTSETMSTP LMRTSDPGER PSLLTRASSS GEMSLPLMRA
810 820 830 840 850
PASGEIATPL RSPAYGAMSA PQMTATASGM MSSMPQVKAP ISGAMSMPLT
860 870 880 890 900
RSTASGGMSM PLMRAPDSRV TSTSQMMPTA SGDMCTLPVR APASGGVSSP
910 920 930 940 950
LVRAPASGTM STPLRRPSAC ETVSTELMRA SASGHMSTAQ TTAMVSGGMS
960 970 980 990 1000
KPLMRAPASG TMPMPLMSAM ASGEMSMPLM ETMASGATST LQTSVANSRS
1010 1020 1030 1040 1050
MSLSQTTYTV SGRMATAPIR ASASGARSTS FMRASVSGSM PMPLPRATAS
1060 1070 1080 1090 1100
GCGMGMSMPQ MTATDSRGMS TPLMRASGPG TMSTPQTAFG VMSTPEIKAT
1110 1120 1130 1140 1150
DSGEASTSHI NITASGSKPT SHMTATTPET AKPPPKEVPS FGMLTPALCY
1160 1170 1180 1190 1200
LLEEQEAARG SCSVEEEMEI DEEKQMKGFL DDSERMAFLV SLHLGAAERW
1210 1220 1230 1240 1250
FILQMEVGEP LSHENKSFLR RSQGIYDSLS EIDILSAVLC HPKQGQKSVR
1260 1270 1280 1290 1300
QYATDFLLLA RHLSWSDAIL RTRFLEGLSE AVTTKMGRIF LKVAGSLKEL
1310 1320 1330 1340 1350
IDRSLYTECQ LAEEKDSPGN SSQVLPTACK RNNEEAMGNE LSSQQQTEEH
1360 1370 1380
QHVSKRCYYL KEHGDPQEGL HDHLGQSTGH HQKAHTNK
Length:1,388
Mass (Da):144,280
Last modified:October 1, 2002 - v1
Checksum:i19A18E68DC8C5A06
GO

Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
E5RKA1E5RKA1_HUMAN
Retrotransposon Gag-like protein 9
RTL9
88Annotation score:

Sequence cautioni

The sequence BAA92556 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.Curated

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Natural variantiVAR_051318777P → S. Corresponds to variant dbSNP:rs35495390Ensembl.1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY121804 mRNA Translation: AAM82752.1
AB037739 mRNA Translation: BAA92556.1 Different initiation.
BC113670 mRNA Translation: AAI13671.1
BC117184 mRNA Translation: AAI17185.1
CCDSiCCDS14552.1
RefSeqiNP_065820.1, NM_020769.2
XP_011529300.1, XM_011530998.2
XP_011529301.1, XM_011530999.2
XP_016885183.1, XM_017029694.1
XP_016885184.1, XM_017029695.1
UniGeneiHs.201071

Genome annotation databases

EnsembliENST00000465301; ENSP00000419786; ENSG00000243978
ENST00000540313; ENSP00000441452; ENSG00000243978
GeneIDi57529
KEGGihsa:57529
UCSCiuc004eor.2 human

Keywords - Coding sequence diversityi

Polymorphism

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY121804 mRNA Translation: AAM82752.1
AB037739 mRNA Translation: BAA92556.1 Different initiation.
BC113670 mRNA Translation: AAI13671.1
BC117184 mRNA Translation: AAI17185.1
CCDSiCCDS14552.1
RefSeqiNP_065820.1, NM_020769.2
XP_011529300.1, XM_011530998.2
XP_011529301.1, XM_011530999.2
XP_016885183.1, XM_017029694.1
XP_016885184.1, XM_017029695.1
UniGeneiHs.201071

3D structure databases

ProteinModelPortaliQ8NET4
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi121588, 7 interactors
IntActiQ8NET4, 5 interactors
MINTiQ8NET4
STRINGi9606.ENSP00000419786

PTM databases

iPTMnetiQ8NET4
PhosphoSitePlusiQ8NET4

Polymorphism and mutation databases

BioMutaiRGAG1
DMDMi74715429

Proteomic databases

PaxDbiQ8NET4
PeptideAtlasiQ8NET4
PRIDEiQ8NET4
ProteomicsDBi73213

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000465301; ENSP00000419786; ENSG00000243978
ENST00000540313; ENSP00000441452; ENSG00000243978
GeneIDi57529
KEGGihsa:57529
UCSCiuc004eor.2 human

Organism-specific databases

CTDi57529
EuPathDBiHostDB:ENSG00000243978.8
GeneCardsiRTL9
HGNCiHGNC:29245 RTL9
HPAiHPA001242
neXtProtiNX_Q8NET4
OpenTargetsiENSG00000243978
PharmGKBiPA134934891
HUGEiSearch...
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410IRCF Eukaryota
ENOG410ZEBE LUCA
GeneTreeiENSGT00730000111416
HOGENOMiHOG000231451
HOVERGENiHBG080283
InParanoidiQ8NET4
OMAiMGRIFLK
OrthoDBiEOG091G02TH
PhylomeDBiQ8NET4
TreeFamiTF334822

Miscellaneous databases

GenomeRNAii57529
PROiPR:Q8NET4

Gene expression databases

BgeeiENSG00000243978 Expressed in 42 organ(s), highest expression level in testis
CleanExiHS_RGAG1
ExpressionAtlasiQ8NET4 baseline and differential
GenevisibleiQ8NET4 HS

Family and domain databases

ProtoNetiSearch...

Entry informationi

Entry nameiRTL9_HUMAN
AccessioniPrimary (citable) accession number: Q8NET4
Secondary accession number(s): Q9P2M8
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 31, 2006
Last sequence update: October 1, 2002
Last modified: September 12, 2018
This is version 97 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  2. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  3. Human chromosome X
    Human chromosome X: entries, gene names and cross-references to MIM
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again