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Protein

Acrosin-binding protein

Gene

ACRBP

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May be involved in packaging and condensation of the acrosin zymogen in the acrosomal matrix via its association with proacrosin.By similarity

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Acrosin-binding protein
Alternative name(s):
Cancer/testis antigen 23
Short name:
CT23
Cancer/testis antigen OY-TES-1
Proacrosin-binding protein sp32
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ACRBPImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 12

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000111644.7

Human Gene Nomenclature Database

More...
HGNCi
HGNC:17195 ACRBP

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
608352 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q8NEB7

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Cytoplasmic vesicle, Secreted

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
84519

Open Targets

More...
OpenTargetsi
ENSG00000111644

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA24452

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
ACRBP

Domain mapping of disease mutations (DMDM)

More...
DMDMi
74730232

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 25Sequence analysisAdd BLAST25
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_000022751626 – 543Acrosin-binding proteinAdd BLAST518

<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM/processing</a> section describes post-translational modifications (PTMs). This subsection <strong>complements</strong> the information provided at the sequence level or describes modifications for which <strong>position-specific data is not yet available</strong>.<p><a href='/help/post-translational_modification' target='_top'>More...</a></p>Post-translational modificationi

The N-terminus is blocked.By similarity
Phosphorylated on Tyr residues in capacitated sperm.By similarity

Keywords - PTMi

Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q8NEB7

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q8NEB7

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q8NEB7

PeptideAtlas

More...
PeptideAtlasi
Q8NEB7

PRoteomics IDEntifications database

More...
PRIDEi
Q8NEB7

ProteomicsDB human proteome resource

More...
ProteomicsDBi
73146

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q8NEB7

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q8NEB7

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Expression restricted to testis in normal tissue. Expressed in a wide spectrum of cancers, including bladder, breast, liver, lung and colon cancers.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000111644 Expressed in 136 organ(s), highest expression level in right testis

CleanEx database of gene expression profiles

More...
CleanExi
HS_ACRBP

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q8NEB7 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q8NEB7 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA039081
HPA039082

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Binds proacrosin.By similarity

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
124113, 1 interactor

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000229243

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

More...
ProteinModelPortali
Q8NEB7

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Keywords - Domaini

Signal

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410IH17 Eukaryota
ENOG410YFR0 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000000826

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000033789

The HOVERGEN Database of Homologous Vertebrate Genes

More...
HOVERGENi
HBG080819

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q8NEB7

Identification of Orthologs from Complete Genome Data

More...
OMAi
EQCHSEA

Database of Orthologous Groups

More...
OrthoDBi
961418at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q8NEB7

TreeFam database of animal gene trees

More...
TreeFami
TF336597

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR036058 Kazal_dom_sf
IPR009865 Proacrosin-bd

The PANTHER Classification System

More...
PANTHERi
PTHR21362 PTHR21362, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF07222 PBP_sp32, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF100895 SSF100895, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

This entry has 1 described isoform and 4 potential isoforms that are computationally mapped.Show allAlign All

Q8NEB7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MRKPAAGFLP SLLKVLLLPL APAAAQDSTQ ASTPGSPLSP TEYERFFALL
60 70 80 90 100
TPTWKAETTC RLRATHGCRN PTLVQLDQYE NHGLVPDGAV CSNLPYASWF
110 120 130 140 150
ESFCQFTHYR CSNHVYYAKR VLCSQPVSIL SPNTLKEIEA SAEVSPTTMT
160 170 180 190 200
SPISPHFTVT ERQTFQPWPE RLSNNVEELL QSSLSLGGQE QAPEHKQEQG
210 220 230 240 250
VEHRQEPTQE HKQEEGQKQE EQEEEQEEEG KQEEGQGTKE GREAVSQLQT
260 270 280 290 300
DSEPKFHSES LSSNPSSFAP RVREVESTPM IMENIQELIR SAQEIDEMNE
310 320 330 340 350
IYDENSYWRN QNPGSLLQLP HTEALLVLCY SIVENTCIIT PTAKAWKYME
360 370 380 390 400
EEILGFGKSV CDSLGRRHMS TCALCDFCSL KLEQCHSEAS LQRQQCDTSH
410 420 430 440 450
KTPFVSPLLA SQSLSIGNQV GSPESGRFYG LDLYGGLHMD FWCARLATKG
460 470 480 490 500
CEDVRVSGWL QTEFLSFQDG DFPTKICDTD YIQYPNYCSF KSQQCLMRNR
510 520 530 540
NRKVSRMRCL QNETYSALSP GKSEDVVLRW SQEFSTLTLG QFG
Length:543
Mass (Da):61,359
Last modified:October 1, 2002 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i44D0F23583522DD9
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
E7EP66E7EP66_HUMAN
Acrosin-binding protein
ACRBP
510Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F5H5S8F5H5S8_HUMAN
Acrosin-binding protein
ACRBP
319Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F5H2C2F5H2C2_HUMAN
Acrosin-binding protein
ACRBP
173Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F5H3P4F5H3P4_HUMAN
Acrosin-binding protein
ACRBP
100Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti32S → P in BAB39388 (PubMed:11248070).Curated1
Sequence conflicti316L → F in BAB39388 (PubMed:11248070).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_050633336T → A. Corresponds to variant dbSNP:rs3741923Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AB051833 mRNA Translation: BAB39388.1
BC033010 mRNA Translation: AAH33010.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS8554.1

NCBI Reference Sequences

More...
RefSeqi
NP_115878.2, NM_032489.2

UniGene gene-oriented nucleotide sequence clusters

More...
UniGenei
Hs.123239

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000229243; ENSP00000229243; ENSG00000111644

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
84519

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:84519

UCSC genome browser

More...
UCSCi
uc001qpu.2 human

Keywords - Coding sequence diversityi

Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB051833 mRNA Translation: BAB39388.1
BC033010 mRNA Translation: AAH33010.1
CCDSiCCDS8554.1
RefSeqiNP_115878.2, NM_032489.2
UniGeneiHs.123239

3D structure databases

ProteinModelPortaliQ8NEB7
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi124113, 1 interactor
STRINGi9606.ENSP00000229243

PTM databases

iPTMnetiQ8NEB7
PhosphoSitePlusiQ8NEB7

Polymorphism and mutation databases

BioMutaiACRBP
DMDMi74730232

Proteomic databases

EPDiQ8NEB7
jPOSTiQ8NEB7
PaxDbiQ8NEB7
PeptideAtlasiQ8NEB7
PRIDEiQ8NEB7
ProteomicsDBi73146

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
84519
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000229243; ENSP00000229243; ENSG00000111644
GeneIDi84519
KEGGihsa:84519
UCSCiuc001qpu.2 human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
84519
DisGeNETi84519
EuPathDBiHostDB:ENSG00000111644.7

GeneCards: human genes, protein and diseases

More...
GeneCardsi
ACRBP
HGNCiHGNC:17195 ACRBP
HPAiHPA039081
HPA039082
MIMi608352 gene
neXtProtiNX_Q8NEB7
OpenTargetsiENSG00000111644
PharmGKBiPA24452

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiENOG410IH17 Eukaryota
ENOG410YFR0 LUCA
GeneTreeiENSGT00390000000826
HOGENOMiHOG000033789
HOVERGENiHBG080819
InParanoidiQ8NEB7
OMAiEQCHSEA
OrthoDBi961418at2759
PhylomeDBiQ8NEB7
TreeFamiTF336597

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
ACRBP human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
84519

Protein Ontology

More...
PROi
PR:Q8NEB7

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSG00000111644 Expressed in 136 organ(s), highest expression level in right testis
CleanExiHS_ACRBP
ExpressionAtlasiQ8NEB7 baseline and differential
GenevisibleiQ8NEB7 HS

Family and domain databases

InterProiView protein in InterPro
IPR036058 Kazal_dom_sf
IPR009865 Proacrosin-bd
PANTHERiPTHR21362 PTHR21362, 1 hit
PfamiView protein in Pfam
PF07222 PBP_sp32, 1 hit
SUPFAMiSSF100895 SSF100895, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiACRBP_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q8NEB7
Secondary accession number(s): Q9BY87
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 7, 2006
Last sequence update: October 1, 2002
Last modified: January 16, 2019
This is version 118 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 12
    Human chromosome 12: entries, gene names and cross-references to MIM
  2. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  3. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  4. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
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