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Entry version 118 (08 May 2019)
Sequence version 2 (25 Nov 2008)
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Protein

Protein FAM13C

Gene

FAM13C

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Protein FAM13C
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:FAM13C
Synonyms:FAM13C1
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 10

Organism-specific databases

Human Gene Nomenclature Database

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HGNCi
HGNC:19371 FAM13C

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q8NE31

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
220965

Open Targets

More...
OpenTargetsi
ENSG00000148541

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA164719657

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
FAM13C

Domain mapping of disease mutations (DMDM)

More...
DMDMi
215273980

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000589221 – 585Protein FAM13CAdd BLAST585

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei131PhosphoserineBy similarity1
Modified residuei238PhosphoserineBy similarity1
Modified residuei385PhosphoserineBy similarity1
Modified residuei386PhosphoserineBy similarity1

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q8NE31

PeptideAtlas

More...
PeptideAtlasi
Q8NE31

PRoteomics IDEntifications database

More...
PRIDEi
Q8NE31

ProteomicsDB human proteome resource

More...
ProteomicsDBi
73121
73122 [Q8NE31-2]
73123 [Q8NE31-3]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q8NE31

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q8NE31

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000148541 Expressed in 189 organ(s), highest expression level in corpus callosum

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q8NE31 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q8NE31 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA037888

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction_section%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="http://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated on a monthly basis. Each binary interaction is displayed on a separate line.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
128665, 17 interactors

Protein interaction database and analysis system

More...
IntActi
Q8NE31, 14 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000481854

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q8NE31

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the FAM13 family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410IJJ8 Eukaryota
ENOG410YAKN LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00950000183033

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000112468

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q8NE31

Database of Orthologous Groups

More...
OrthoDBi
1026411at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q8NE31

TreeFam database of animal gene trees

More...
TreeFami
TF328895

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR039102 FAM13

The PANTHER Classification System

More...
PANTHERi
PTHR15904 PTHR15904, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (5+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 5 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 5 described isoforms and 7 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q8NE31-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MFSCFCFSLQ DNSFSSTTVT ECDEDPVSLH EDQTDCSSLR DENNKENYPD
60 70 80 90 100
AGALVEEHAP PSWEPQQQNV EATVLVDSVL RPSMGNFKSR KPKSIFKAES
110 120 130 140 150
GRSHGESQET EHVVSSQSEC QVRAGTPAHE SPQNNAFKCQ ETVRLQPRID
160 170 180 190 200
QRTAISPKDA FETRQDLNEE EAAQVHGVKD PAPASTQSVL ADGTDSADPS
210 220 230 240 250
PVHKDGQNEA DSAPEDLHSV GTSRLLYHIT DGDNPLLSPR CSIFSQSQRF
260 270 280 290 300
NLDPESAPSP PSTQQFMMPR SSSRCSCGDG KEPQTITQLT KHIQSLKRKI
310 320 330 340 350
RKFEEKFEQE KKYRPSHGDK TSNPEVLKWM NDLAKGRKQL KELKLKLSEE
360 370 380 390 400
QGSAPKGPPR NLLCEQPTVP RENGKPEAAG PEPSSSGEET PDAALTCLKE
410 420 430 440 450
RREQLPPQED SKVTKQDKNL IKPLYDRYRI IKQILSTPSL IPTIQEEEDS
460 470 480 490 500
DEDRPQGSQQ PSLADPASHL PVGDHLTYSN ETEPVRALLP DEKKEVKPPA
510 520 530 540 550
LSMSNLHEAT MPVLLDHLRE TRADKKRLRK ALREFEEQFF KQTGRSPQKE
560 570 580
DRIPMADEYY EYKHIKAKLR LLEVLISKQD VAKTI
Length:585
Mass (Da):65,727
Last modified:November 25, 2008 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i209AA62323588462
GO
Isoform 2 (identifier: Q8NE31-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     445-458: QEEEDSDEDRPQGS → VSQDTCMLLLCTDV
     459-585: Missing.

Show »
Length:458
Mass (Da):50,936
Checksum:i999B283F4CAD11A9
GO
Isoform 3 (identifier: Q8NE31-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     315-412: Missing.

Show »
Length:487
Mass (Da):55,007
Checksum:iA056D4B9E7A78F92
GO
Isoform 4 (identifier: Q8NE31-4) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-83: Missing.

Show »
Length:502
Mass (Da):56,476
Checksum:i1D776CDD6F2D5C81
GO
Isoform 5 (identifier: Q8NE31-5) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-83: Missing.
     445-445: Missing.

Note: No experimental confirmation available.
Show »
Length:501
Mass (Da):56,348
Checksum:i2EE7AD71583AFD64
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 7 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A087X216A0A087X216_HUMAN
Family with sequence similarity 13,...
FAM13C FAM13C1, hCG_41127
605Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
B7Z2K3B7Z2K3_HUMAN
cDNA FLJ54631, highly similar to Pr...
FAM13C
573Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A087X0M7A0A087X0M7_HUMAN
Protein FAM13C
FAM13C
606Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H0YGW3H0YGW3_HUMAN
Protein FAM13C
FAM13C
134Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
D6RIX4D6RIX4_HUMAN
Protein FAM13C
FAM13C
25Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A087X1H9A0A087X1H9_HUMAN
Protein FAM13C
FAM13C
49Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A087X2G4A0A087X2G4_HUMAN
Protein FAM13C
FAM13C
50Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_04766182P → H1 PublicationCorresponds to variant dbSNP:rs17853626Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0442861 – 83Missing in isoform 4 and isoform 5. 1 PublicationAdd BLAST83
Alternative sequenceiVSP_035840315 – 412Missing in isoform 3. 1 PublicationAdd BLAST98
Alternative sequenceiVSP_035841445 – 458QEEED…RPQGS → VSQDTCMLLLCTDV in isoform 2. 1 PublicationAdd BLAST14
Alternative sequenceiVSP_045812445Missing in isoform 5. Curated1
Alternative sequenceiVSP_035842459 – 585Missing in isoform 2. 1 PublicationAdd BLAST127

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AK316542 mRNA Translation: BAH14913.1
AC025038 Genomic DNA No translation available.
AL355474 Genomic DNA No translation available.
CH471083 Genomic DNA Translation: EAW54190.1
BC036453 mRNA Translation: AAH36453.1
BC064431 mRNA Translation: AAH64431.1
U79304 mRNA Translation: AAB50228.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS31207.1 [Q8NE31-3]
CCDS44406.1 [Q8NE31-4]
CCDS53538.1 [Q8NE31-5]
CCDS7255.1 [Q8NE31-1]

NCBI Reference Sequences

More...
RefSeqi
NP_001001971.1, NM_001001971.2 [Q8NE31-3]
NP_001137245.1, NM_001143773.1 [Q8NE31-4]
NP_001160170.1, NM_001166698.1 [Q8NE31-5]
NP_001334769.1, NM_001347840.1 [Q8NE31-4]
NP_001334771.1, NM_001347842.1 [Q8NE31-5]
NP_001334772.1, NM_001347843.1
NP_001334773.1, NM_001347844.1 [Q8NE31-5]
NP_001334774.1, NM_001347845.1
NP_001334776.1, NM_001347847.1 [Q8NE31-4]
NP_001334777.1, NM_001347848.1
NP_001334779.1, NM_001347850.1
NP_937858.2, NM_198215.3 [Q8NE31-1]
XP_006717765.1, XM_006717702.3 [Q8NE31-4]
XP_016871375.1, XM_017015886.1 [Q8NE31-5]
XP_016871378.1, XM_017015889.1 [Q8NE31-5]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000422313; ENSP00000400241; ENSG00000148541 [Q8NE31-2]
ENST00000468840; ENSP00000423896; ENSG00000148541 [Q8NE31-4]
ENST00000611933; ENSP00000481830; ENSG00000148541 [Q8NE31-3]
ENST00000618427; ENSP00000480677; ENSG00000148541 [Q8NE31-5]
ENST00000618804; ENSP00000481854; ENSG00000148541 [Q8NE31-1]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
220965

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:220965

UCSC genome browser

More...
UCSCi
uc001jkp.4 human [Q8NE31-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK316542 mRNA Translation: BAH14913.1
AC025038 Genomic DNA No translation available.
AL355474 Genomic DNA No translation available.
CH471083 Genomic DNA Translation: EAW54190.1
BC036453 mRNA Translation: AAH36453.1
BC064431 mRNA Translation: AAH64431.1
U79304 mRNA Translation: AAB50228.1
CCDSiCCDS31207.1 [Q8NE31-3]
CCDS44406.1 [Q8NE31-4]
CCDS53538.1 [Q8NE31-5]
CCDS7255.1 [Q8NE31-1]
RefSeqiNP_001001971.1, NM_001001971.2 [Q8NE31-3]
NP_001137245.1, NM_001143773.1 [Q8NE31-4]
NP_001160170.1, NM_001166698.1 [Q8NE31-5]
NP_001334769.1, NM_001347840.1 [Q8NE31-4]
NP_001334771.1, NM_001347842.1 [Q8NE31-5]
NP_001334772.1, NM_001347843.1
NP_001334773.1, NM_001347844.1 [Q8NE31-5]
NP_001334774.1, NM_001347845.1
NP_001334776.1, NM_001347847.1 [Q8NE31-4]
NP_001334777.1, NM_001347848.1
NP_001334779.1, NM_001347850.1
NP_937858.2, NM_198215.3 [Q8NE31-1]
XP_006717765.1, XM_006717702.3 [Q8NE31-4]
XP_016871375.1, XM_017015886.1 [Q8NE31-5]
XP_016871378.1, XM_017015889.1 [Q8NE31-5]

3D structure databases

SMRiQ8NE31
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi128665, 17 interactors
IntActiQ8NE31, 14 interactors
STRINGi9606.ENSP00000481854

PTM databases

iPTMnetiQ8NE31
PhosphoSitePlusiQ8NE31

Polymorphism and mutation databases

BioMutaiFAM13C
DMDMi215273980

Proteomic databases

PaxDbiQ8NE31
PeptideAtlasiQ8NE31
PRIDEiQ8NE31
ProteomicsDBi73121
73122 [Q8NE31-2]
73123 [Q8NE31-3]

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
220965
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000422313; ENSP00000400241; ENSG00000148541 [Q8NE31-2]
ENST00000468840; ENSP00000423896; ENSG00000148541 [Q8NE31-4]
ENST00000611933; ENSP00000481830; ENSG00000148541 [Q8NE31-3]
ENST00000618427; ENSP00000480677; ENSG00000148541 [Q8NE31-5]
ENST00000618804; ENSP00000481854; ENSG00000148541 [Q8NE31-1]
GeneIDi220965
KEGGihsa:220965
UCSCiuc001jkp.4 human [Q8NE31-1]

Organism-specific databases

Comparative Toxicogenomics Database

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CTDi
220965
DisGeNETi220965

GeneCards: human genes, protein and diseases

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GeneCardsi
FAM13C

H-Invitational Database, human transcriptome db

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H-InvDBi
HIX0025949
HGNCiHGNC:19371 FAM13C
HPAiHPA037888
neXtProtiNX_Q8NE31
OpenTargetsiENSG00000148541
PharmGKBiPA164719657

GenAtlas: human gene database

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GenAtlasi
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Phylogenomic databases

eggNOGiENOG410IJJ8 Eukaryota
ENOG410YAKN LUCA
GeneTreeiENSGT00950000183033
HOGENOMiHOG000112468
InParanoidiQ8NE31
OrthoDBi1026411at2759
PhylomeDBiQ8NE31
TreeFamiTF328895

Miscellaneous databases

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

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GenomeRNAii
220965

Protein Ontology

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PROi
PR:Q8NE31

Gene expression databases

BgeeiENSG00000148541 Expressed in 189 organ(s), highest expression level in corpus callosum
ExpressionAtlasiQ8NE31 baseline and differential
GenevisibleiQ8NE31 HS

Family and domain databases

InterProiView protein in InterPro
IPR039102 FAM13
PANTHERiPTHR15904 PTHR15904, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiFA13C_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q8NE31
Secondary accession number(s): B7ZB77
, Q5T631, Q6P2M3, Q99787
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 11, 2003
Last sequence update: November 25, 2008
Last modified: May 8, 2019
This is version 118 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Human chromosome 10
    Human chromosome 10: entries, gene names and cross-references to MIM
  3. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  4. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
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