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Protein

Transmembrane protein 161B

Gene

TMEM161B

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Transmembrane protein 161B
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
ORF Names:UNQ679/PRO1313
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 5

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000164180.13

Human Gene Nomenclature Database

More...
HGNCi
HGNC:28483 TMEM161B

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q8NDZ6

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei107 – 127HelicalSequence analysisAdd BLAST21
Transmembranei136 – 156HelicalSequence analysisAdd BLAST21
Transmembranei169 – 189HelicalSequence analysisAdd BLAST21
Transmembranei228 – 248HelicalSequence analysisAdd BLAST21
Transmembranei265 – 285HelicalSequence analysisAdd BLAST21
Transmembranei305 – 325HelicalSequence analysisAdd BLAST21
Transmembranei367 – 387HelicalSequence analysisAdd BLAST21
Transmembranei459 – 479HelicalSequence analysisAdd BLAST21

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

More...
OpenTargetsi
ENSG00000164180

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA145147987

Polymorphism and mutation databases

Domain mapping of disease mutations (DMDM)

More...
DMDMi
74730190

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002880891 – 487Transmembrane protein 161BAdd BLAST487

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi34N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi135N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi203N-linked (GlcNAc...) asparagineSequence analysis1

Keywords - PTMi

Glycoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q8NDZ6

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q8NDZ6

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q8NDZ6

PeptideAtlas

More...
PeptideAtlasi
Q8NDZ6

PRoteomics IDEntifications database

More...
PRIDEi
Q8NDZ6

ProteomicsDB human proteome resource

More...
ProteomicsDBi
73102
73103 [Q8NDZ6-2]
73104 [Q8NDZ6-3]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q8NDZ6

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q8NDZ6

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000164180 Expressed in 194 organ(s), highest expression level in epithelial cell of pancreas

CleanEx database of gene expression profiles

More...
CleanExi
HS_TMEM161B

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q8NDZ6 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q8NDZ6 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA044562

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
127493, 7 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000296595

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

More...
ProteinModelPortali
Q8NDZ6

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q8NDZ6

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the TMEM161 family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG3978 Eukaryota
ENOG410XPZC LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000000672

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000273873

The HOVERGEN Database of Homologous Vertebrate Genes

More...
HOVERGENi
HBG063501

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q8NDZ6

Identification of Orthologs from Complete Genome Data

More...
OMAi
SIFYYLC

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q8NDZ6

TreeFam database of animal gene trees

More...
TreeFami
TF314570

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR019395 Transmembrane_161A/B

The PANTHER Classification System

More...
PANTHERi
PTHR13624 PTHR13624, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF10268 Tmemb_161AB, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (3+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 3 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 3 described isoforms and 7 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q8NDZ6-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MGVIGIQLVV TMVMASVMQK IIPHYSLARW LLCNGSLRWY QHPTEEELRI
60 70 80 90 100
LAGKQQKGKT KKDRKYNGHI ESKPLTIPKD IDLHLETKSV TEVDTLALHY
110 120 130 140 150
FPEYQWLVDF TVAATVVYLV TEVYYNFMKP TQEMNISLVW CLLVLSFAIK
160 170 180 190 200
VLFSLTTHYF KVEDGGERSV CVTFGFFFFV KAMAVLIVTE NYLEFGLETG
210 220 230 240 250
FTNFSDSAMQ FLEKQGLESQ SPVSKLTFKF FLAIFCSFIG AFLTFPGLRL
260 270 280 290 300
AQMHLDALNL ATEKITQTLL HINFLAPLFM VLLWVKPITK DYIMNPPLGK
310 320 330 340 350
ESIPLMTEAT FDTLRLWLII LLCALRLAMM RSHLQAYLNL AQKCVDQMKK
360 370 380 390 400
EAGRISTVEL QKMVARVFYY LCVIALQYVA PLVMLLHTTL LLKTLGNHSW
410 420 430 440 450
GIYPESISTL PVDNSLLSNS VYSELPSAEG KMKVTVTQIT VALSSLKNIF
460 470 480
TPLLFRGLLS FLTWWIAACL FSTSLFGLFY HQYLTVA
Length:487
Mass (Da):55,482
Last modified:October 1, 2002 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i18A1D716F7F87369
GO
Isoform 2 (identifier: Q8NDZ6-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     302-307: SIPLMT → ISPSGR
     308-487: Missing.

Show »
Length:307
Mass (Da):35,098
Checksum:iEBFA6C6EE6BA762B
GO
Isoform 3 (identifier: Q8NDZ6-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-127: Missing.
     268-487: Missing.

Note: No experimental confirmation available.
Show »
Length:140
Mass (Da):15,828
Checksum:iDDA3640E2DFBAD67
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 7 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
E9PCX5E9PCX5_HUMAN
Transmembrane protein 161B
TMEM161B
502Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
B7Z6T3B7Z6T3_HUMAN
Transmembrane protein 161B
TMEM161B
476Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
D6RAK4D6RAK4_HUMAN
Transmembrane protein 161B
TMEM161B
217Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
B7Z6A5B7Z6A5_HUMAN
Transmembrane protein 161B
TMEM161B
278Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
D6RBE8D6RBE8_HUMAN
Transmembrane protein 161B
TMEM161B
178Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
E9PFW6E9PFW6_HUMAN
Transmembrane protein 161B
TMEM161B
153Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
D6RAR3D6RAR3_HUMAN
Transmembrane protein 161B
TMEM161B
121Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting. The information stored in this subsection is used to automatically construct alternative protein sequence(s) for display.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0256471 – 127Missing in isoform 3. 1 PublicationAdd BLAST127
Alternative sequenceiVSP_025648268 – 487Missing in isoform 3. 1 PublicationAdd BLAST220
Alternative sequenceiVSP_025649302 – 307SIPLMT → ISPSGR in isoform 2. 1 Publication6
Alternative sequenceiVSP_025650308 – 487Missing in isoform 2. 1 PublicationAdd BLAST180

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AY358693 mRNA Translation: AAQ89056.1
BX648757 mRNA Translation: CAI56713.1
BC037287 mRNA Translation: AAH37287.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS4065.1 [Q8NDZ6-1]

NCBI Reference Sequences

More...
RefSeqi
NP_699185.1, NM_153354.4 [Q8NDZ6-1]

UniGene gene-oriented nucleotide sequence clusters

More...
UniGenei
Hs.379972

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000296595; ENSP00000296595; ENSG00000164180 [Q8NDZ6-1]
ENST00000510089; ENSP00000423380; ENSG00000164180 [Q8NDZ6-3]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
153396

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:153396

UCSC genome browser

More...
UCSCi
uc003kjc.5 human [Q8NDZ6-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY358693 mRNA Translation: AAQ89056.1
BX648757 mRNA Translation: CAI56713.1
BC037287 mRNA Translation: AAH37287.1
CCDSiCCDS4065.1 [Q8NDZ6-1]
RefSeqiNP_699185.1, NM_153354.4 [Q8NDZ6-1]
UniGeneiHs.379972

3D structure databases

ProteinModelPortaliQ8NDZ6
SMRiQ8NDZ6
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi127493, 7 interactors
STRINGi9606.ENSP00000296595

PTM databases

iPTMnetiQ8NDZ6
PhosphoSitePlusiQ8NDZ6

Polymorphism and mutation databases

DMDMi74730190

Proteomic databases

EPDiQ8NDZ6
MaxQBiQ8NDZ6
PaxDbiQ8NDZ6
PeptideAtlasiQ8NDZ6
PRIDEiQ8NDZ6
ProteomicsDBi73102
73103 [Q8NDZ6-2]
73104 [Q8NDZ6-3]

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
153396
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000296595; ENSP00000296595; ENSG00000164180 [Q8NDZ6-1]
ENST00000510089; ENSP00000423380; ENSG00000164180 [Q8NDZ6-3]
GeneIDi153396
KEGGihsa:153396
UCSCiuc003kjc.5 human [Q8NDZ6-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
153396
EuPathDBiHostDB:ENSG00000164180.13

GeneCards: human genes, protein and diseases

More...
GeneCardsi
TMEM161B

H-Invitational Database, human transcriptome db

More...
H-InvDBi
HIX0024841
HGNCiHGNC:28483 TMEM161B
HPAiHPA044562
neXtProtiNX_Q8NDZ6
OpenTargetsiENSG00000164180
PharmGKBiPA145147987

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG3978 Eukaryota
ENOG410XPZC LUCA
GeneTreeiENSGT00390000000672
HOGENOMiHOG000273873
HOVERGENiHBG063501
InParanoidiQ8NDZ6
OMAiSIFYYLC
PhylomeDBiQ8NDZ6
TreeFamiTF314570

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
TMEM161B human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
153396

Protein Ontology

More...
PROi
PR:Q8NDZ6

Gene expression databases

BgeeiENSG00000164180 Expressed in 194 organ(s), highest expression level in epithelial cell of pancreas
CleanExiHS_TMEM161B
ExpressionAtlasiQ8NDZ6 baseline and differential
GenevisibleiQ8NDZ6 HS

Family and domain databases

InterProiView protein in InterPro
IPR019395 Transmembrane_161A/B
PANTHERiPTHR13624 PTHR13624, 1 hit
PfamiView protein in Pfam
PF10268 Tmemb_161AB, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiT161B_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q8NDZ6
Secondary accession number(s): Q5CZH7, Q6UWQ6
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 29, 2007
Last sequence update: October 1, 2002
Last modified: September 12, 2018
This is version 100 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Human chromosome 5
    Human chromosome 5: entries, gene names and cross-references to MIM
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