MAPK1IP1L

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: MAPK-interacting and spindle-stabilizing protein-like Alternative name(s): Mitogen-activated protein kinase 1-interacting protein 1-like
Gene namesⁱ	Name:MAPK1IP1L Synonyms:C14orf32
Organismⁱ	Homo sapiens (Human)
Taxonomic identifierⁱ	9606 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo
Proteomesⁱ	UP000005640 Componentⁱ: Chromosome 14

Organism-specific databases

EuPathDBⁱ	HostDB:ENSG00000168175.14
Human Gene Nomenclature Database More...HGNCⁱ	HGNC:19840 MAPK1IP1L
neXtProtⁱ	NX_Q8NDC0

Pathology & Biotechⁱ

Organism-specific databases

Open Targets More...OpenTargetsⁱ	ENSG00000168175
PharmGKBⁱ	PA162395015

Polymorphism and mutation databases

BioMutaⁱ	MAPK1IP1L

BioMutaⁱ

MAPK1IP1L

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Initiator methionineⁱ		RemovedCombined sources1 Publication
ChainⁱPRO_0000209890	2 – 245	MAPK-interacting and spindle-stabilizing protein-likeAdd BLAST		244

Amino acid modifications

Feature key	Position(s)	DescriptionActions	Length
Modified residueⁱ	2	N-acetylserineCombined sources1 Publication	1
Modified residueⁱ	2	PhosphoserineCombined sources	1
Modified residueⁱ	6	PhosphoserineCombined sources	1
Modified residueⁱ	15	PhosphoserineCombined sources	1

Keywords - PTMⁱ

Acetylation, Phosphoprotein

Proteomic databases

EPDⁱ	Q8NDC0
MaxQB - The MaxQuant DataBase More...MaxQBⁱ	Q8NDC0
PaxDbⁱ	Q8NDC0
PeptideAtlas More...PeptideAtlasⁱ	Q8NDC0
PRIDEⁱ	Q8NDC0
ProteomicsDBⁱ	73012

PTM databases

iPTMnetⁱ	Q8NDC0
PhosphoSitePlusⁱ	Q8NDC0

Expressionⁱ

Gene expression databases

Bgeeⁱ	ENSG00000168175 Expressed in 239 organ(s), highest expression level in cauda epididymis
CleanExⁱ	HS_MAPK1IP1L
Genevisibleⁱ	Q8NDC0 HS

Organism-specific databases

Human Protein Atlas More...HPAⁱ	HPA034506

HPAⁱ

HPA034506

Interactionⁱ

Binary interactionsⁱ

With	Entry	#Exp.	IntAct
	G2XKQ0	5	EBI-741424,EBI-10175576
ARHGEF16	Q5VV41	3	EBI-741424,EBI-1057448
C1orf94	Q6P1W5	4	EBI-741424,EBI-946029
CEP55	Q53EZ4	3	EBI-741424,EBI-747776
EWSR1	Q01844	5	EBI-741424,EBI-739737
HGS	A0A0S2Z4Q4	3	EBI-741424,EBI-16429135
HGS	O14964	6	EBI-741424,EBI-740220
HNRNPUL1	Q9BUJ2	5	EBI-741424,EBI-1018153
LENG8	Q96PV6	4	EBI-741424,EBI-739546
RBFOX2	O43251	3	EBI-741424,EBI-746056
SS18L1	O75177	3	EBI-741424,EBI-744674
SUMO1	P63165	3	EBI-741424,EBI-80140
TFG	Q92734	7	EBI-741424,EBI-357061
UBE2I	Q7KZS0	5	EBI-741424,EBI-10180829
VPS37C	A5D8V6	5	EBI-741424,EBI-2559305

Protein-protein interaction databases

BioGridⁱ	125030, 29 interactors
IntActⁱ	Q8NDC0, 27 interactors
STRINGⁱ	9606.ENSP00000378851

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	Q8NDC0
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Compositional bias

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Compositional biasⁱ	27 – 241	Pro-richAdd BLAST		215

Sequence similaritiesⁱ

Belongs to the MISS family.Curated

Phylogenomic databases

eggNOGⁱ	ENOG410IX7N Eukaryota ENOG4111CPI LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00730000111340
HOGENOMⁱ	HOG000059660
HOVERGENⁱ	HBG039557
InParanoidⁱ	Q8NDC0
OMAⁱ	GPWGSMP
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G15C3
PhylomeDBⁱ	Q8NDC0

Family and domain databases

InterProⁱ	View protein in InterPro IPR031653 MISS
PANTHERⁱ	PTHR35973 PTHR35973, 1 hit
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF15822 MISS, 1 hit

Sequenceⁱ

Sequence statusⁱ: Complete.

Sequence processingⁱ: The displayed sequence is further processed into a mature form.

Q8NDC0-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MSDEFSLADA LPEHSPAKTS AVSNTKPGQP PQGWPGSNPW NNPSAPSSVP 
        60         70         80         90        100
SGLPPSATPS TVPFGPAPTG MYPSVPPTGP PPGPPAPFPP SGPSCPPPGG 
       110        120        130        140        150
PYPAPTVPGP GPTGPYPTPN MPFPELPRPY GAPTDPAAAG PLGPWGSMSS 
       160        170        180        190        200
GPWAPGMGGQ YPTPNMPYPS PGPYPAPPPP QAPGAAPPVP WGTVPPGAWG 
       210        220        230        240 
PPAPYPAPTG SYPTPGLYPT PSNPFQVPSG PSGAPPMPGG PHSYH

Length:245

Mass (Da):24,269

Last modified:January 23, 2007 - v4

Checksum:ⁱ8B03ADFE2581D5C5

GO

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AK315501 mRNA Translation: BAG37885.1 AL834285 mRNA Translation: CAD38959.2 AL139316 Genomic DNA No translation available. CH471061 Genomic DNA Translation: EAW80657.1 BC015621 mRNA Translation: AAH15621.1
The Consensus CDS (CCDS) project More...CCDSⁱ	CCDS32085.1
NCBI Reference Sequences More...RefSeqⁱ	NP_653179.1, NM_144578.3
UniGeneⁱ	Hs.594338

Genome annotation databases

Ensemblⁱ	ENST00000395468; ENSP00000378851; ENSG00000168175 ENST00000622254; ENSP00000481882; ENSG00000168175
GeneIDⁱ	93487
KEGGⁱ	hsa:93487
UCSC genome browser More...UCSCⁱ	uc001xbq.2 human

Protein	Similar proteins		Species	Score	Length	Source
Q8NDC0	MAPK-interacting and spindle-stabilizing protein-like		PONAB		245	UniRef100_Q8NDC0
MAPK1IP1L isoform 1		PANTR		245
Uncharacterized protein		PANPA		245
Uncharacterized protein		NOMLE		245
Mitogen-activated protein kinase 1 interacting protein 1 like		GORGO		245
+2

Protein	Similar proteins		Species	Score	Length	Source
Q8NDC0	MAPK-interacting and spindle-stabilizing protein-like		PONAB		245	UniRef90_Q8NDC0
MAPK-interacting and spindle-stabilizing protein-like		MACFA		245
MAPK1IP1L isoform 1		PANTR		245
Uncharacterized protein		PANPA		245
Uncharacterized protein		NOMLE		245
+101

Protein	Similar proteins		Species	Score	Length	Source
Q8NDC0	MAPK-interacting and spindle-stabilizing protein-like		PONAB		245	UniRef50_Q8NDC0
MAPK-interacting and spindle-stabilizing protein-like		MACFA		245
MAPK-interacting and spindle-stabilizing protein-like		BOVIN		240
MAPK1IP1L isoform 1		PANTR		245
Uncharacterized protein		PANPA		245
+111

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AK315501 mRNA Translation: BAG37885.1 AL834285 mRNA Translation: CAD38959.2 AL139316 Genomic DNA No translation available. CH471061 Genomic DNA Translation: EAW80657.1 BC015621 mRNA Translation: AAH15621.1
CCDSⁱ	CCDS32085.1
RefSeqⁱ	NP_653179.1, NM_144578.3
UniGeneⁱ	Hs.594338

3D structure databases

ProteinModelPortalⁱ	Q8NDC0
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

BioGridⁱ	125030, 29 interactors
IntActⁱ	Q8NDC0, 27 interactors
STRINGⁱ	9606.ENSP00000378851

PTM databases

iPTMnetⁱ	Q8NDC0
PhosphoSitePlusⁱ	Q8NDC0

Polymorphism and mutation databases

BioMutaⁱ	MAPK1IP1L

BioMutaⁱ

MAPK1IP1L

Proteomic databases

EPDⁱ	Q8NDC0
MaxQBⁱ	Q8NDC0
PaxDbⁱ	Q8NDC0
PeptideAtlasⁱ	Q8NDC0
PRIDEⁱ	Q8NDC0
ProteomicsDBⁱ	73012

Protocols and materials databases

The DNASU plasmid repository More...DNASUⁱ	93487
Structural Biology Knowledgebase	Search...

Genome annotation databases

Ensemblⁱ	ENST00000395468; ENSP00000378851; ENSG00000168175 ENST00000622254; ENSP00000481882; ENSG00000168175
GeneIDⁱ	93487
KEGGⁱ	hsa:93487
UCSCⁱ	uc001xbq.2 human

Organism-specific databases

CTDⁱ	93487
EuPathDBⁱ	HostDB:ENSG00000168175.14
GeneCardsⁱ	MAPK1IP1L
HGNCⁱ	HGNC:19840 MAPK1IP1L
HPAⁱ	HPA034506
neXtProtⁱ	NX_Q8NDC0
OpenTargetsⁱ	ENSG00000168175
PharmGKBⁱ	PA162395015
GenAtlas: human gene database More...GenAtlasⁱ	Search...

Phylogenomic databases

eggNOGⁱ	ENOG410IX7N Eukaryota ENOG4111CPI LUCA
GeneTreeⁱ	ENSGT00730000111340
HOGENOMⁱ	HOG000059660
HOVERGENⁱ	HBG039557
InParanoidⁱ	Q8NDC0
OMAⁱ	GPWGSMP
OrthoDBⁱ	EOG091G15C3
PhylomeDBⁱ	Q8NDC0

Miscellaneous databases

ChiTaRSⁱ	MAPK1IP1L human
GeneWikiⁱ	C14orf32
GenomeRNAiⁱ	93487
Protein Ontology More...PROⁱ	PR:Q8NDC0

Gene expression databases

Bgeeⁱ	ENSG00000168175 Expressed in 239 organ(s), highest expression level in cauda epididymis
CleanExⁱ	HS_MAPK1IP1L
Genevisibleⁱ	Q8NDC0 HS

Family and domain databases

InterProⁱ	View protein in InterPro IPR031653 MISS
PANTHERⁱ	PTHR35973 PTHR35973, 1 hit
Pfamⁱ	View protein in Pfam PF15822 MISS, 1 hit
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	MISSL_HUMAN
Accessionⁱ	Q8NDC0Primary (citable) accession number: Q8NDC0 Secondary accession number(s): B2RDD8, Q96BG5
Entry historyⁱ	Integrated into UniProtKB/Swiss-Prot:	July 11, 2003
	Last sequence update:	January 23, 2007
	Last modified:	November 7, 2018
	This is version 122 of the entry and version 4 of the sequence. See complete history.
Entry statusⁱ	Reviewed (UniProtKB/Swiss-Prot)
Annotation program	Chordata Protein Annotation Program
Disclaimer	Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Direct protein sequencing, Reference proteome

Documents

SIMILARITY comments
Index of protein domains and families
Human chromosome 14
Human chromosome 14: entries, gene names and cross-references to MIM

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - Q8NDC0 (MISSL_HUMAN)

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MAPK-interacting and spindle-stabilizing protein-like

Select a section on the left to see content.

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Polymorphism and mutation databases

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Amino acid modifications

Proteomic databases

PTM databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Organism-specific databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Compositional bias

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Phylogenomic databases

Family and domain databases

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

PTM databases

Polymorphism and mutation databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Documents

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Names & Taxonomyⁱ

Pathology & Biotechⁱ

PTM / Processingⁱ

Expressionⁱ

Interactionⁱ

Structureⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ