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Protein

MAPK-interacting and spindle-stabilizing protein-like

Gene

MAPK1IP1L

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Recommended name:
MAPK-interacting and spindle-stabilizing protein-like
Alternative name(s):
Mitogen-activated protein kinase 1-interacting protein 1-like
Gene namesi
Name:MAPK1IP1L
Synonyms:C14orf32
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 14

Organism-specific databases

EuPathDBiHostDB:ENSG00000168175.14
HGNCiHGNC:19840 MAPK1IP1L
neXtProtiNX_Q8NDC0

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000168175
PharmGKBiPA162395015

Polymorphism and mutation databases

BioMutaiMAPK1IP1L

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemovedCombined sources1 Publication
ChainiPRO_00002098902 – 245MAPK-interacting and spindle-stabilizing protein-likeAdd BLAST244

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei2N-acetylserineCombined sources1 Publication1
Modified residuei2PhosphoserineCombined sources1
Modified residuei6PhosphoserineCombined sources1
Modified residuei15PhosphoserineCombined sources1

Keywords - PTMi

Acetylation, Phosphoprotein

Proteomic databases

EPDiQ8NDC0
MaxQBiQ8NDC0
PaxDbiQ8NDC0
PeptideAtlasiQ8NDC0
PRIDEiQ8NDC0
ProteomicsDBi73012

PTM databases

iPTMnetiQ8NDC0
PhosphoSitePlusiQ8NDC0

Expressioni

Gene expression databases

BgeeiENSG00000168175 Expressed in 239 organ(s), highest expression level in cauda epididymis
CleanExiHS_MAPK1IP1L
GenevisibleiQ8NDC0 HS

Organism-specific databases

HPAiHPA034506

Interactioni

Binary interactionsi

Protein-protein interaction databases

BioGridi125030, 29 interactors
IntActiQ8NDC0, 27 interactors
STRINGi9606.ENSP00000378851

Structurei

3D structure databases

ProteinModelPortaliQ8NDC0
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi27 – 241Pro-richAdd BLAST215

Sequence similaritiesi

Belongs to the MISS family.Curated

Phylogenomic databases

eggNOGiENOG410IX7N Eukaryota
ENOG4111CPI LUCA
GeneTreeiENSGT00730000111340
HOGENOMiHOG000059660
HOVERGENiHBG039557
InParanoidiQ8NDC0
OMAiGPWGSMP
OrthoDBiEOG091G15C3
PhylomeDBiQ8NDC0

Family and domain databases

InterProiView protein in InterPro
IPR031653 MISS
PANTHERiPTHR35973 PTHR35973, 1 hit
PfamiView protein in Pfam
PF15822 MISS, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q8NDC0-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSDEFSLADA LPEHSPAKTS AVSNTKPGQP PQGWPGSNPW NNPSAPSSVP
60 70 80 90 100
SGLPPSATPS TVPFGPAPTG MYPSVPPTGP PPGPPAPFPP SGPSCPPPGG
110 120 130 140 150
PYPAPTVPGP GPTGPYPTPN MPFPELPRPY GAPTDPAAAG PLGPWGSMSS
160 170 180 190 200
GPWAPGMGGQ YPTPNMPYPS PGPYPAPPPP QAPGAAPPVP WGTVPPGAWG
210 220 230 240
PPAPYPAPTG SYPTPGLYPT PSNPFQVPSG PSGAPPMPGG PHSYH
Length:245
Mass (Da):24,269
Last modified:January 23, 2007 - v4
Checksum:i8B03ADFE2581D5C5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK315501 mRNA Translation: BAG37885.1
AL834285 mRNA Translation: CAD38959.2
AL139316 Genomic DNA No translation available.
CH471061 Genomic DNA Translation: EAW80657.1
BC015621 mRNA Translation: AAH15621.1
CCDSiCCDS32085.1
RefSeqiNP_653179.1, NM_144578.3
UniGeneiHs.594338

Genome annotation databases

EnsembliENST00000395468; ENSP00000378851; ENSG00000168175
ENST00000622254; ENSP00000481882; ENSG00000168175
GeneIDi93487
KEGGihsa:93487
UCSCiuc001xbq.2 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK315501 mRNA Translation: BAG37885.1
AL834285 mRNA Translation: CAD38959.2
AL139316 Genomic DNA No translation available.
CH471061 Genomic DNA Translation: EAW80657.1
BC015621 mRNA Translation: AAH15621.1
CCDSiCCDS32085.1
RefSeqiNP_653179.1, NM_144578.3
UniGeneiHs.594338

3D structure databases

ProteinModelPortaliQ8NDC0
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi125030, 29 interactors
IntActiQ8NDC0, 27 interactors
STRINGi9606.ENSP00000378851

PTM databases

iPTMnetiQ8NDC0
PhosphoSitePlusiQ8NDC0

Polymorphism and mutation databases

BioMutaiMAPK1IP1L

Proteomic databases

EPDiQ8NDC0
MaxQBiQ8NDC0
PaxDbiQ8NDC0
PeptideAtlasiQ8NDC0
PRIDEiQ8NDC0
ProteomicsDBi73012

Protocols and materials databases

DNASUi93487
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000395468; ENSP00000378851; ENSG00000168175
ENST00000622254; ENSP00000481882; ENSG00000168175
GeneIDi93487
KEGGihsa:93487
UCSCiuc001xbq.2 human

Organism-specific databases

CTDi93487
EuPathDBiHostDB:ENSG00000168175.14
GeneCardsiMAPK1IP1L
HGNCiHGNC:19840 MAPK1IP1L
HPAiHPA034506
neXtProtiNX_Q8NDC0
OpenTargetsiENSG00000168175
PharmGKBiPA162395015
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410IX7N Eukaryota
ENOG4111CPI LUCA
GeneTreeiENSGT00730000111340
HOGENOMiHOG000059660
HOVERGENiHBG039557
InParanoidiQ8NDC0
OMAiGPWGSMP
OrthoDBiEOG091G15C3
PhylomeDBiQ8NDC0

Miscellaneous databases

ChiTaRSiMAPK1IP1L human
GeneWikiiC14orf32
GenomeRNAii93487
PROiPR:Q8NDC0

Gene expression databases

BgeeiENSG00000168175 Expressed in 239 organ(s), highest expression level in cauda epididymis
CleanExiHS_MAPK1IP1L
GenevisibleiQ8NDC0 HS

Family and domain databases

InterProiView protein in InterPro
IPR031653 MISS
PANTHERiPTHR35973 PTHR35973, 1 hit
PfamiView protein in Pfam
PF15822 MISS, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiMISSL_HUMAN
AccessioniPrimary (citable) accession number: Q8NDC0
Secondary accession number(s): B2RDD8, Q96BG5
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 11, 2003
Last sequence update: January 23, 2007
Last modified: November 7, 2018
This is version 122 of the entry and version 4 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Human chromosome 14
    Human chromosome 14: entries, gene names and cross-references to MIM
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Main funding by: National Institutes of Health

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