UniProtKB - Q8NDC0 (MISSL_HUMAN)
Protein
MAPK-interacting and spindle-stabilizing protein-like
Gene
MAPK1IP1L
Organism
Homo sapiens (Human)
Status
Names & Taxonomyi
Protein namesi | Recommended name: MAPK-interacting and spindle-stabilizing protein-likeAlternative name(s): Mitogen-activated protein kinase 1-interacting protein 1-like |
Gene namesi | Name:MAPK1IP1L Synonyms:C14orf32 |
Organismi | Homo sapiens (Human) |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:19840, MAPK1IP1L |
neXtProti | NX_Q8NDC0 |
VEuPathDBi | HostDB:ENSG00000168175.14 |
Pathology & Biotechi
Organism-specific databases
DisGeNETi | 93487 |
OpenTargetsi | ENSG00000168175 |
PharmGKBi | PA162395015 |
Miscellaneous databases
Pharosi | Q8NDC0, Tbio |
Genetic variation databases
BioMutai | MAPK1IP1L |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Initiator methioninei | RemovedCombined sources1 Publication | |||
ChainiPRO_0000209890 | 2 – 245 | MAPK-interacting and spindle-stabilizing protein-likeAdd BLAST | 244 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Modified residuei | 2 | N-acetylserineCombined sources1 Publication | 1 | |
Modified residuei | 2 | PhosphoserineCombined sources | 1 | |
Modified residuei | 6 | PhosphoserineCombined sources | 1 | |
Modified residuei | 15 | PhosphoserineCombined sources | 1 |
Keywords - PTMi
Acetylation, PhosphoproteinProteomic databases
EPDi | Q8NDC0 |
jPOSTi | Q8NDC0 |
MassIVEi | Q8NDC0 |
MaxQBi | Q8NDC0 |
PaxDbi | Q8NDC0 |
PeptideAtlasi | Q8NDC0 |
PRIDEi | Q8NDC0 |
ProteomicsDBi | 73012 |
PTM databases
GlyGeni | Q8NDC0, 1 site, 1 O-linked glycan (1 site) |
iPTMneti | Q8NDC0 |
PhosphoSitePlusi | Q8NDC0 |
Expressioni
Gene expression databases
Bgeei | ENSG00000168175, Expressed in cauda epididymis and 251 other tissues |
Genevisiblei | Q8NDC0, HS |
Organism-specific databases
HPAi | ENSG00000168175, Low tissue specificity |
Interactioni
Binary interactionsi
Hide detailsQ8NDC0
Protein-protein interaction databases
BioGRIDi | 125030, 41 interactors |
IntActi | Q8NDC0, 30 interactors |
STRINGi | 9606.ENSP00000378851 |
Miscellaneous databases
RNActi | Q8NDC0, protein |
Family & Domainsi
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 27 – 241 | Pro-richAdd BLAST | 215 |
Sequence similaritiesi
Belongs to the MISS family.Curated
Phylogenomic databases
eggNOGi | ENOG502RYAB, Eukaryota |
GeneTreei | ENSGT00730000111340 |
HOGENOMi | CLU_063887_0_0_1 |
InParanoidi | Q8NDC0 |
OMAi | TWGPSPP |
OrthoDBi | 1626851at2759 |
PhylomeDBi | Q8NDC0 |
Family and domain databases
InterProi | View protein in InterPro IPR031653, MISS |
PANTHERi | PTHR35973, PTHR35973, 1 hit |
Pfami | View protein in Pfam PF15822, MISS, 1 hit |
i Sequence
Sequence statusi: Complete.
: The displayed sequence is further processed into a mature form. Sequence processingi
Q8NDC0-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MSDEFSLADA LPEHSPAKTS AVSNTKPGQP PQGWPGSNPW NNPSAPSSVP
60 70 80 90 100
SGLPPSATPS TVPFGPAPTG MYPSVPPTGP PPGPPAPFPP SGPSCPPPGG
110 120 130 140 150
PYPAPTVPGP GPTGPYPTPN MPFPELPRPY GAPTDPAAAG PLGPWGSMSS
160 170 180 190 200
GPWAPGMGGQ YPTPNMPYPS PGPYPAPPPP QAPGAAPPVP WGTVPPGAWG
210 220 230 240
PPAPYPAPTG SYPTPGLYPT PSNPFQVPSG PSGAPPMPGG PHSYH
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AK315501 mRNA Translation: BAG37885.1 AL834285 mRNA Translation: CAD38959.2 AL139316 Genomic DNA No translation available. CH471061 Genomic DNA Translation: EAW80657.1 BC015621 mRNA Translation: AAH15621.1 |
CCDSi | CCDS32085.1 |
RefSeqi | NP_653179.1, NM_144578.3 |
Genome annotation databases
Ensembli | ENST00000395468; ENSP00000378851; ENSG00000168175 ENST00000622254; ENSP00000481882; ENSG00000168175 |
GeneIDi | 93487 |
KEGGi | hsa:93487 |
UCSCi | uc001xbq.2, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AK315501 mRNA Translation: BAG37885.1 AL834285 mRNA Translation: CAD38959.2 AL139316 Genomic DNA No translation available. CH471061 Genomic DNA Translation: EAW80657.1 BC015621 mRNA Translation: AAH15621.1 |
CCDSi | CCDS32085.1 |
RefSeqi | NP_653179.1, NM_144578.3 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
BioGRIDi | 125030, 41 interactors |
IntActi | Q8NDC0, 30 interactors |
STRINGi | 9606.ENSP00000378851 |
PTM databases
GlyGeni | Q8NDC0, 1 site, 1 O-linked glycan (1 site) |
iPTMneti | Q8NDC0 |
PhosphoSitePlusi | Q8NDC0 |
Genetic variation databases
BioMutai | MAPK1IP1L |
Proteomic databases
EPDi | Q8NDC0 |
jPOSTi | Q8NDC0 |
MassIVEi | Q8NDC0 |
MaxQBi | Q8NDC0 |
PaxDbi | Q8NDC0 |
PeptideAtlasi | Q8NDC0 |
PRIDEi | Q8NDC0 |
ProteomicsDBi | 73012 |
Protocols and materials databases
Antibodypediai | 49801, 79 antibodies |
DNASUi | 93487 |
Genome annotation databases
Ensembli | ENST00000395468; ENSP00000378851; ENSG00000168175 ENST00000622254; ENSP00000481882; ENSG00000168175 |
GeneIDi | 93487 |
KEGGi | hsa:93487 |
UCSCi | uc001xbq.2, human |
Organism-specific databases
CTDi | 93487 |
DisGeNETi | 93487 |
GeneCardsi | MAPK1IP1L |
HGNCi | HGNC:19840, MAPK1IP1L |
HPAi | ENSG00000168175, Low tissue specificity |
neXtProti | NX_Q8NDC0 |
OpenTargetsi | ENSG00000168175 |
PharmGKBi | PA162395015 |
VEuPathDBi | HostDB:ENSG00000168175.14 |
GenAtlasi | Search... |
Phylogenomic databases
eggNOGi | ENOG502RYAB, Eukaryota |
GeneTreei | ENSGT00730000111340 |
HOGENOMi | CLU_063887_0_0_1 |
InParanoidi | Q8NDC0 |
OMAi | TWGPSPP |
OrthoDBi | 1626851at2759 |
PhylomeDBi | Q8NDC0 |
Enzyme and pathway databases
PathwayCommonsi | Q8NDC0 |
Miscellaneous databases
BioGRID-ORCSi | 93487, 13 hits in 996 CRISPR screens |
ChiTaRSi | MAPK1IP1L, human |
GeneWikii | C14orf32 |
GenomeRNAii | 93487 |
Pharosi | Q8NDC0, Tbio |
PROi | PR:Q8NDC0 |
RNActi | Q8NDC0, protein |
Gene expression databases
Bgeei | ENSG00000168175, Expressed in cauda epididymis and 251 other tissues |
Genevisiblei | Q8NDC0, HS |
Family and domain databases
InterProi | View protein in InterPro IPR031653, MISS |
PANTHERi | PTHR35973, PTHR35973, 1 hit |
Pfami | View protein in Pfam PF15822, MISS, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | MISSL_HUMAN | |
Accessioni | Q8NDC0Primary (citable) accession number: Q8NDC0 Secondary accession number(s): B2RDD8, Q96BG5 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | July 11, 2003 |
Last sequence update: | January 23, 2007 | |
Last modified: | April 7, 2021 | |
This is version 136 of the entry and version 4 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |
Miscellaneousi
Keywords - Technical termi
Direct protein sequencing, Reference proteomeDocuments
- Human chromosome 14
Human chromosome 14: entries, gene names and cross-references to MIM - SIMILARITY comments
Index of protein domains and families