Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 140 (17 Jun 2020)
Sequence version 2 (24 Oct 2003)
Previous versions | rss
Help videoAdd a publicationFeedback
Protein

Paraneoplastic antigen Ma1

Gene

PNMA1

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Miscellaneous

Antibodies against PNMA1 are present in sera from patients suffering of paraneoplastic neurological disorders.

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionTumor antigen

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Paraneoplastic antigen Ma1
Alternative name(s):
37 kDa neuronal protein
Neuron- and testis-specific protein 1
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:PNMA1
Synonyms:MA1
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 14

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000176903.4

Human Gene Nomenclature Database

More...
HGNCi
HGNC:9158 PNMA1

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
604010 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q8ND90

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
9240

Open Targets

More...
OpenTargetsi
ENSG00000176903

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA33481

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q8ND90 Tbio

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
PNMA1

Domain mapping of disease mutations (DMDM)

More...
DMDMi
37999715

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001551991 – 353Paraneoplastic antigen Ma1Add BLAST353

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q8ND90

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q8ND90

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q8ND90

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q8ND90

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q8ND90

PeptideAtlas

More...
PeptideAtlasi
Q8ND90

PRoteomics IDEntifications database

More...
PRIDEi
Q8ND90

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
72992

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q8ND90

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q8ND90

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Testis- and brain-specific. In some cancer patients, specifically expressed by paraneoplastic tumor cells.2 Publications

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000176903 Expressed in nucleus accumbens and 98 other tissues

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q8ND90 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
ENSG00000176903 Low tissue specificity

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Q8ND90
With#Exp.IntAct
ANKRD36BP1 [Q96IX9]3EBI-302345,EBI-744859
APTX [Q7Z2E3]3EBI-302345,EBI-847814
APTX - isoform 7 [Q7Z2E3-7]3EBI-302345,EBI-12298187
ARHGEF6 [Q15052]3EBI-302345,EBI-1642523
ARID5A [Q03989]5EBI-302345,EBI-948603
ASMTL [O95671]3EBI-302345,EBI-743231
ATP5PO [P48047]4EBI-302345,EBI-355815
ATP6V1G1 [O75348]3EBI-302345,EBI-711802
BEX2 [Q9BXY8]3EBI-302345,EBI-745073
BYSL [Q13895]3EBI-302345,EBI-358049
C1orf109 [Q9NX04]3EBI-302345,EBI-8643161
C21orf58 [Q0VAL7]3EBI-302345,EBI-10226774
C8orf33 [Q9H7E9]3EBI-302345,EBI-715389
CARHSP1 [Q9Y2V2]3EBI-302345,EBI-718719
CBX8 [Q9HC52]3EBI-302345,EBI-712912
CCDC146 - isoform 2 [Q8IYE0-2]3EBI-302345,EBI-10247802
CCDC198 [E9PSE9]3EBI-302345,EBI-11748295
CCDC198 [Q9NVL8]3EBI-302345,EBI-10238351
CCNG1 [P51959]3EBI-302345,EBI-3905829
CDK18 [Q07002]3EBI-302345,EBI-746238
CFAP53 [Q96M91]3EBI-302345,EBI-742422
CHIC2 [Q9UKJ5]3EBI-302345,EBI-741528
CNNM3 [Q8NE01]3EBI-302345,EBI-741032
CNNM3 - isoform 3 [Q8NE01-3]3EBI-302345,EBI-10269984
COX5B [P10606]3EBI-302345,EBI-1053725
CTNNA3 - isoform 2 [Q9UI47-2]3EBI-302345,EBI-11962928
DAXX [Q9UER7]5EBI-302345,EBI-77321
DCTN4 [Q9UJW0]3EBI-302345,EBI-2134033
EHHADH [Q08426]3EBI-302345,EBI-2339219
ENKD1 [Q9H0I2]4EBI-302345,EBI-744099
FAM107A - isoform 3 [O95990-3]3EBI-302345,EBI-10192902
FAM110A [Q9BQ89]3EBI-302345,EBI-1752811
FAM161A [Q3B820]3EBI-302345,EBI-719941
FAM161B [Q96MY7]3EBI-302345,EBI-7225287
FBF1 - isoform 6 [Q8TES7-6]3EBI-302345,EBI-10244131
FBXL18 [Q96D16]5EBI-302345,EBI-744419
FEM1C [Q96JP0]3EBI-302345,EBI-2515330
FOXD4L1 [Q9NU39]3EBI-302345,EBI-11320806
FOXD4L3 [Q6VB84]3EBI-302345,EBI-11961494
GADD45GIP1 [Q8TAE8]3EBI-302345,EBI-372506
GEM [P55040]3EBI-302345,EBI-744104
GPANK1 [O95872]4EBI-302345,EBI-751540
GPR25 [O00155]3EBI-302345,EBI-10178951
GTPBP10 [A4D1E9]4EBI-302345,EBI-5453796
HAPLN2 [Q9GZV7]3EBI-302345,EBI-11956675
hCG_1987119 [A0A024R8L2]3EBI-302345,EBI-14103818
HCK - isoform 2 [P08631-2]3EBI-302345,EBI-9834454
HDAC4 [P56524]3EBI-302345,EBI-308629
HGS [A0A0S2Z4Q4]3EBI-302345,EBI-16429135
HOXB9 [P17482]6EBI-302345,EBI-745290
IGFN1 - isoform 5 [Q86VF2-5]3EBI-302345,EBI-11955401
INO80B [Q9C086]3EBI-302345,EBI-715611
KANSL1 [Q7Z3B3]3EBI-302345,EBI-740244
LAGE3 [Q14657]3EBI-302345,EBI-1052105
LIN37 [Q96GY3]3EBI-302345,EBI-748884
LMO3 - isoform 4 [Q8TAP4-4]5EBI-302345,EBI-11742507
LNX1 [Q8TBB1]7EBI-302345,EBI-739832
MAB21L2 [Q9Y586]3EBI-302345,EBI-6659161
MACIR [Q96GV9]3EBI-302345,EBI-2350695
MARK4 [Q96L34]2EBI-302345,EBI-302319
MCM7 [P33993]3EBI-302345,EBI-355924
MED8 - isoform 2 [Q96G25-2]3EBI-302345,EBI-10286267
METTL17 [Q9H7H0]7EBI-302345,EBI-749353
METTL17 - isoform 2 [Q9H7H0-2]6EBI-302345,EBI-11098807
MGC50722 [Q8IVT4]3EBI-302345,EBI-14086479
MRPL10 [Q7Z7H8]3EBI-302345,EBI-723524
MRPL11 [Q9Y3B7]6EBI-302345,EBI-5453723
MRPL23 [Q16540]3EBI-302345,EBI-1046141
MYOZ1 [Q9NP98]3EBI-302345,EBI-744402
NPBWR2 [P48146]3EBI-302345,EBI-10210114
NSMF - isoform 2 [Q6X4W1-2]3EBI-302345,EBI-12028784
NUDT16L1 [Q9BRJ7]3EBI-302345,EBI-2949792
PARD3 [Q8TEW0]4EBI-302345,EBI-81968
PARD6A [Q9NPB6]2EBI-302345,EBI-81876
PARD6B [Q9BYG5]2EBI-302345,EBI-295391
PAUF [C3PTT6]3EBI-302345,EBI-3505892
PER1 [J3QSH9]3EBI-302345,EBI-10178671
PIN1 [Q13526]3EBI-302345,EBI-714158
PIN4 [Q9Y237]3EBI-302345,EBI-714599
PKN1 [Q16512]3EBI-302345,EBI-602382
PKN3 [Q6P5Z2]3EBI-302345,EBI-1384335
PNMA5 [Q96PV4]6EBI-302345,EBI-10171633
PNMA6A [P0CW24]7EBI-302345,EBI-721270
POLDIP3 [Q8WUT1]3EBI-302345,EBI-10276663
POLL - isoform 2 [Q9UGP5-2]3EBI-302345,EBI-10320765
POLM [Q6PIY2]3EBI-302345,EBI-10253863
PRKCI [P41743]2EBI-302345,EBI-286199
PRPF18 [Q99633]3EBI-302345,EBI-2798416
PRPF31 [Q8WWY3]11EBI-302345,EBI-1567797
PSMA1 [P25786]6EBI-302345,EBI-359352
RAD51D [O75771]3EBI-302345,EBI-1055693
RBM41 [Q96IZ5]3EBI-302345,EBI-740773
RPP25 [Q9BUL9]3EBI-302345,EBI-366570
RPP25L [Q8N5L8]3EBI-302345,EBI-10189722
RSPH9 [Q9H1X1]3EBI-302345,EBI-10305303
RSRC2 - isoform 2 [Q7L4I2-2]3EBI-302345,EBI-10256202
RTP5 [Q14D33]6EBI-302345,EBI-10217913
RUSC1 [Q9BVN2]8EBI-302345,EBI-6257312
SCAND1 [P57086]3EBI-302345,EBI-745846
SCNM1 [Q9BWG6]8EBI-302345,EBI-748391
SDCBP [O00560]8EBI-302345,EBI-727004
SEMA4C [Q9C0C4]6EBI-302345,EBI-10303490
SH2D4A [Q9H788]6EBI-302345,EBI-747035
SHC3 [Q92529]3EBI-302345,EBI-79084
SHISA3 [A0PJX4]3EBI-302345,EBI-10171518
SLC25A48 [Q6ZT89]3EBI-302345,EBI-10255185
SLIRP [Q9GZT3]3EBI-302345,EBI-1050793
SMIM3 [Q9BZL3]3EBI-302345,EBI-741850
SNRPB - isoform SM-B [P14678-2]6EBI-302345,EBI-372475
SNRPB2 [P08579]5EBI-302345,EBI-1053651
SPATC1L [Q9H0A9]3EBI-302345,EBI-372911
SPATC1L - isoform 2 [Q9H0A9-2]3EBI-302345,EBI-11995806
SPG7 [Q9UQ90]7EBI-302345,EBI-717201
STAMBPL1 [Q96FJ0]3EBI-302345,EBI-745021
SUV39H2 [Q9H5I1]5EBI-302345,EBI-723127
TASOR2 [Q5VWN6]3EBI-302345,EBI-745958
TCEA2 [Q15560]3EBI-302345,EBI-710310
TCEANC [Q8N8B7]3EBI-302345,EBI-954696
TCEANC - isoform 2 [Q8N8B7-2]3EBI-302345,EBI-11955057
TCL1B [O95988]3EBI-302345,EBI-727338
TEAD4 [A0A0S2Z4F2]3EBI-302345,EBI-16429215
TEAD4 [D3DUQ6]3EBI-302345,EBI-10176734
TEAD4 [Q15561]3EBI-302345,EBI-747736
TMSB4X [Q0P5Q0]3EBI-302345,EBI-10226570
TNNI1 [P19237]6EBI-302345,EBI-746692
TRIM42 [Q8IWZ5]3EBI-302345,EBI-5235829
TRIM74 - isoform 2 [Q86UV6-2]3EBI-302345,EBI-10259086
TRPV6 [Q9Y260]3EBI-302345,EBI-750052
TSHZ2 [Q9NRE2]3EBI-302345,EBI-10687282
TSPYL4 [Q9UJ04]3EBI-302345,EBI-308511
TTC23 - isoform 3 [Q5W5X9-3]3EBI-302345,EBI-9090990
TTC9C [Q8N5M4]3EBI-302345,EBI-2851213
TXNDC9 [O14530]3EBI-302345,EBI-707554
UBQLN1 [Q9UMX0]4EBI-302345,EBI-741480
UBQLN1 - isoform 2 [Q9UMX0-2]3EBI-302345,EBI-10173939
URB1-AS1 [Q96HZ7]3EBI-302345,EBI-10288943
USP2 [O75604]3EBI-302345,EBI-743272
VBP1 [P61758]3EBI-302345,EBI-357430
VPS9D1 [Q9Y2B5]3EBI-302345,EBI-9031083
WDR25 [Q64LD2]3EBI-302345,EBI-744560
WDYHV1 [Q96HA8]6EBI-302345,EBI-741158
WT1-AS [Q06250]3EBI-302345,EBI-10223946
ZC2HC1C [Q53FD0]4EBI-302345,EBI-740767
ZCCHC12 [Q6PEW1]10EBI-302345,EBI-748373
ZFYVE26 - isoform 5 [Q68DK2-5]3EBI-302345,EBI-8656416
ZNF148 - isoform 2 [Q9UQR1-2]3EBI-302345,EBI-11742222
ZNF35 [P13682]3EBI-302345,EBI-11041653
ZNF438 [Q7Z4V0]3EBI-302345,EBI-11962468
ZNF564 [Q8TBZ8]3EBI-302345,EBI-10273713
ZNF581 [Q9P0T4]8EBI-302345,EBI-745520
ZNF688 [A0A0S2Z5X4]3EBI-302345,EBI-16429014
Q6ZN966EBI-302345,EBI-10255097

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
114667, 140 interactors

Protein interaction database and analysis system

More...
IntActi
Q8ND90, 183 interactors

Molecular INTeraction database

More...
MINTi
Q8ND90

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000318914

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q8ND90 protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q8ND90

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi335 – 341Poly-Glu7

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the PNMA family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410IIH9 Eukaryota
ENOG410YK5I LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00950000182785

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_014694_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q8ND90

Identification of Orthologs from Complete Genome Data

More...
OMAi
EHTNEVM

Database of Orthologous Groups

More...
OrthoDBi
820525at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q8ND90

TreeFam database of animal gene trees

More...
TreeFami
TF335054

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR026523 PNMA
IPR026528 PNMA1

The PANTHER Classification System

More...
PANTHERi
PTHR23095 PTHR23095, 1 hit
PTHR23095:SF17 PTHR23095:SF17, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF14893 PNMA, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q8ND90-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAMTLLEDWC RGMDVNSQRA LLVWGIPVNC DEAEIEETLQ AAMPQVSYRM
60 70 80 90 100
LGRMFWREEN AKAALLELTG AVDYAAIPRE MPGKGGVWKV LFKPPTSDAE
110 120 130 140 150
FLERLHLFLA REGWTVQDVA RVLGFQNPTP TPGPEMPAEM LNYILDNVIQ
160 170 180 190 200
PLVESIWYKR LTLFSGRDIP GPGEETFDPW LEHTNEVLEE WQVSDVEKRR
210 220 230 240 250
RLMESLRGPA ADVIRILKSN NPAITTAECL KALEQVFGSV ESSRDAQIKF
260 270 280 290 300
LNTYQNPGEK LSAYVIRLEP LLQKVVEKGA IDKDNVNQAR LEQVIAGANH
310 320 330 340 350
SGAIRRQLWL TGAGEGPAPN LFQLLVQIRE EEAKEEEEEA EATLLQLGLE

GHF
Length:353
Mass (Da):39,761
Last modified:October 24, 2003 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iEB7F5B6AEDA25961
GO

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_05359554M → V. Corresponds to variant dbSNP:rs35129712Ensembl.1
Natural variantiVAR_053596215R → P. Corresponds to variant dbSNP:rs34413931Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AF037364 mRNA Translation: AAD13810.3
AF320308 mRNA Translation: AAN05100.1
AK290980 mRNA Translation: BAF83669.1
CH471061 Genomic DNA Translation: EAW81126.1
BC039577 mRNA Translation: AAH39577.1
AL834327 mRNA Translation: CAD38995.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS9818.1

NCBI Reference Sequences

More...
RefSeqi
NP_006020.4, NM_006029.4

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000316836; ENSP00000318914; ENSG00000176903

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
9240

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:9240

UCSC genome browser

More...
UCSCi
uc001xor.2 human

Keywords - Coding sequence diversityi

Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF037364 mRNA Translation: AAD13810.3
AF320308 mRNA Translation: AAN05100.1
AK290980 mRNA Translation: BAF83669.1
CH471061 Genomic DNA Translation: EAW81126.1
BC039577 mRNA Translation: AAH39577.1
AL834327 mRNA Translation: CAD38995.1
CCDSiCCDS9818.1
RefSeqiNP_006020.4, NM_006029.4

3D structure databases

SMRiQ8ND90
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi114667, 140 interactors
IntActiQ8ND90, 183 interactors
MINTiQ8ND90
STRINGi9606.ENSP00000318914

PTM databases

iPTMnetiQ8ND90
PhosphoSitePlusiQ8ND90

Polymorphism and mutation databases

BioMutaiPNMA1
DMDMi37999715

Proteomic databases

EPDiQ8ND90
jPOSTiQ8ND90
MassIVEiQ8ND90
MaxQBiQ8ND90
PaxDbiQ8ND90
PeptideAtlasiQ8ND90
PRIDEiQ8ND90
ProteomicsDBi72992

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
26 187 antibodies

The DNASU plasmid repository

More...
DNASUi
9240

Genome annotation databases

EnsembliENST00000316836; ENSP00000318914; ENSG00000176903
GeneIDi9240
KEGGihsa:9240
UCSCiuc001xor.2 human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
9240
DisGeNETi9240
EuPathDBiHostDB:ENSG00000176903.4

GeneCards: human genes, protein and diseases

More...
GeneCardsi
PNMA1
HGNCiHGNC:9158 PNMA1
HPAiENSG00000176903 Low tissue specificity
MIMi604010 gene
neXtProtiNX_Q8ND90
OpenTargetsiENSG00000176903
PharmGKBiPA33481

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiENOG410IIH9 Eukaryota
ENOG410YK5I LUCA
GeneTreeiENSGT00950000182785
HOGENOMiCLU_014694_0_0_1
InParanoidiQ8ND90
OMAiEHTNEVM
OrthoDBi820525at2759
PhylomeDBiQ8ND90
TreeFamiTF335054

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
9240 5 hits in 790 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
PNMA1 human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
9240
PharosiQ8ND90 Tbio

Protein Ontology

More...
PROi
PR:Q8ND90
RNActiQ8ND90 protein

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSG00000176903 Expressed in nucleus accumbens and 98 other tissues
GenevisibleiQ8ND90 HS

Family and domain databases

InterProiView protein in InterPro
IPR026523 PNMA
IPR026528 PNMA1
PANTHERiPTHR23095 PTHR23095, 1 hit
PTHR23095:SF17 PTHR23095:SF17, 1 hit
PfamiView protein in Pfam
PF14893 PNMA, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiPNMA1_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q8ND90
Secondary accession number(s): A8K4L5, O95144, Q8NG07
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 24, 2003
Last sequence update: October 24, 2003
Last modified: June 17, 2020
This is version 140 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  5. Human chromosome 14
    Human chromosome 14: entries, gene names and cross-references to MIM
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again