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UniProtKB - Q8NCP5 (ZBT44_HUMAN)

Entry version 153 (22 Apr 2020)
Sequence version 1 (01 Oct 2002)
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Protein

Zinc finger and BTB domain-containing protein 44

Gene

ZBTB44

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May be involved in transcriptional regulation.By similarity

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section specifies the position(s) and type(s) of zinc fingers within the protein.<p><a href='/help/zn_fing' target='_top'>More...</a></p>Zinc fingeri399 – 421C2H2-type 1PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri427 – 449C2H2-type 2PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri455 – 479C2H2-type 3PROSITE-ProRule annotationAdd BLAST25
Zinc fingeri487 – 511C2H2-type 4PROSITE-ProRule annotationAdd BLAST25

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDNA-binding
Biological processTranscription, Transcription regulation
LigandMetal-binding, Zinc

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Zinc finger and BTB domain-containing protein 44
Alternative name(s):
BTB/POZ domain-containing protein 15
Zinc finger protein 851
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ZBTB44
Synonyms:BTBD15, ZNF851
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 11

Organism-specific databases

Human Gene Nomenclature Database

More...HGNCi		HGNC:25001 ZBTB44

neXtProt; the human protein knowledge platform

More...neXtProti		NX_Q8NCP5

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

More...OpenTargetsi		ENSG00000196323

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...PharmGKBi		PA162409447

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...Pharosi		Q8NCP5 Tdark

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...BioMutai		ZBTB44

Domain mapping of disease mutations (DMDM)

More...DMDMi		74760158

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002746081 – 570Zinc finger and BTB domain-containing protein 44Add BLAST570

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section describes <strong>covalent linkages</strong> of various types formed <strong>between two proteins (interchain cross-links)</strong> or <strong>between two parts of the same protein (intrachain cross-links)</strong>, except the disulfide bonds that are annotated in the <a href="http://www.uniprot.org/manual/disulfid">'Disulfide bond'</a> subsection.<p><a href='/help/crosslnk' target='_top'>More...</a></p>Cross-linki4Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei135PhosphoserineCombined sources1
Modified residuei159PhosphoserineBy similarity1
Modified residuei161PhosphoserineCombined sources1
Modified residuei165PhosphoserineBy similarity1
Modified residuei191PhosphoserineCombined sources1
Modified residuei194PhosphoserineCombined sources1
Modified residuei200PhosphothreonineBy similarity1
Cross-linki290Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources

Keywords - PTMi

Isopeptide bond, Phosphoprotein, Ubl conjugation

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

More...jPOSTi		Q8NCP5

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...MassIVEi		Q8NCP5

MaxQB - The MaxQuant DataBase

More...MaxQBi		Q8NCP5

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		Q8NCP5

PeptideAtlas

More...PeptideAtlasi		Q8NCP5

PRoteomics IDEntifications database

More...PRIDEi		Q8NCP5

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		72915 [Q8NCP5-1]
72916 [Q8NCP5-2]
72917 [Q8NCP5-3]
72918 [Q8NCP5-4]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		Q8NCP5

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		Q8NCP5

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSG00000196323 Expressed in quadriceps femoris and 216 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		Q8NCP5 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		Q8NCP5 HS

Organism-specific databases

Human Protein Atlas

More...HPAi		ENSG00000196323 Low tissue specificity

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Show more details

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...BioGridi		118842, 28 interactors

Protein interaction database and analysis system

More...IntActi		Q8NCP5, 23 interactors

STRING: functional protein association networks

More...STRINGi		9606.ENSP00000380861

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		Q8NCP5 protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		Q8NCP5

Database of comparative protein structure models

More...ModBasei		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini31 – 98BTBPROSITE-ProRule annotationAdd BLAST68

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi9 – 14Poly-Ser6
Compositional biasi364 – 367Poly-Asp4

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri399 – 421C2H2-type 1PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri427 – 449C2H2-type 2PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri455 – 479C2H2-type 3PROSITE-ProRule annotationAdd BLAST25
Zinc fingeri487 – 511C2H2-type 4PROSITE-ProRule annotationAdd BLAST25

Keywords - Domaini

Repeat, Zinc-finger

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG1721 Eukaryota
COG5048 LUCA

Ensembl GeneTree

More...GeneTreei		ENSGT00940000153306

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_034849_1_0_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q8NCP5

KEGG Orthology (KO)

More...KOi		K10515

Database for complete collections of gene phylogenies

More...PhylomeDBi		Q8NCP5

TreeFam database of animal gene trees

More...TreeFami		TF332673

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR000210 BTB/POZ_dom
IPR011333 SKP1/BTB/POZ_sf
IPR036236 Znf_C2H2_sf
IPR013087 Znf_C2H2_type

Pfam protein domain database

More...Pfami		View protein in Pfam
PF00651 BTB, 1 hit
PF00096 zf-C2H2, 3 hits

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00225 BTB, 1 hit
SM00355 ZnF_C2H2, 4 hits

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF54695 SSF54695, 1 hit
SSF57667 SSF57667, 2 hits

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS50097 BTB, 1 hit
PS00028 ZINC_FINGER_C2H2_1, 4 hits
PS50157 ZINC_FINGER_C2H2_2, 4 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (4+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 4 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform. This section is only present in reviewed entries, i.e. in UniProtKB/Swiss-Prot.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 4 described isoforms and 4 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q8NCP5-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MGVKTFTHSS SSHSQEMLGK LNMLRNDGHF CDITIRVQDK IFRAHKVVLA 
        60         70         80         90        100
ACSDFFRTKL VGQAEDENKN VLDLHHVTVT GFIPLLEYAY TATLSINTEN 
       110        120        130        140        150
IIDVLAAASY MQMFSVASTC SEFMKSSILW NTPNSQPEKG LDAGQENNSN 
       160        170        180        190        200
CNFTSRDGSI SPVSSECSVV ERTIPVCRES RRKRKSYIVM SPESPVKCGT 
       210        220        230        240        250
QTSSPQVLNS SASYSENRNQ PVDSSLAFPW TFPFGIDRRI QPEKVKQAEN 
       260        270        280        290        300
TRTLELPGPS ETGRRMADYV TCESTKTTLP LGTEEDVRVK VERLSDEEVH 
       310        320        330        340        350
EEVSQPVSAS QSSLSDQQTV PGSEQVQEDL LISPQSSSIG SVDEGVSEGL 
       360        370        380        390        400
PTLQSTSSTN APPDDDDRLE NVQYPYQLYI APSTSSTERP SPNGPDRPFQ 
       410        420        430        440        450
CPTCGVRFTR IQNLKQHMLI HSGIKPFQCD RCGKKFTRAY SLKMHRLKHE 
       460        470        480        490        500
GKRCFRCQIC SATFTSFGEY KHHMRVSRHI IRKPRIYECK TCGAMLTNSG 
       510        520        530        540        550
NLIVHLRSLN HEASELANYF QSSDFLVPDY LNQEQEETLV QYDLGEHGFE 
       560        570
SNSSVQMPVI SQYHSKGKEP
Length:570
Mass (Da):63,848
Last modified:October 1, 2002 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i9C0E64DB7D0343DF
GO
Isoform 2 (identifier: Q8NCP5-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     451-570: GKRCFRCQIC...SQYHSKGKEP → VPLQRQGTMIDNSQAVDEMTRNGE

Show »
Length:474
Mass (Da):52,706
Checksum:i81480A579D6847EB
GO
Isoform 3 (identifier: Q8NCP5-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     451-558: Missing.
     562-570: Missing.

Show »
Length:453
Mass (Da):50,333
Checksum:i7EE1FDEDC4452CE0
GO
Isoform 4 (identifier: Q8NCP5-4) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     451-570: GKRCFRCQIC...SQYHSKGKEP → GHPRKSASRSSSATNCC

Show »
Length:467
Mass (Da):51,765
Checksum:iC5E2A4931C6215C8
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
H0YEM9H0YEM9_HUMAN
Zinc finger and BTB domain-containi...
ZBTB44
616Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H0YCZ0H0YCZ0_HUMAN
Zinc finger and BTB domain-containi...
ZBTB44
328Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H7BY22H7BY22_HUMAN
Zinc finger and BTB domain-containi...
ZBTB44
570Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A0A0MTE9A0A0A0MTE9_HUMAN
Zinc finger and BTB domain-containi...
ZBTB44
180Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_030336185K → E1 PublicationCorresponds to variant dbSNP:rs17857365Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_022834451 – 570GKRCF…KGKEP → VPLQRQGTMIDNSQAVDEMT RNGE in isoform 2. 1 PublicationAdd BLAST120
Alternative sequenceiVSP_022835451 – 570GKRCF…KGKEP → GHPRKSASRSSSATNCC in isoform 4. 1 PublicationAdd BLAST120
Alternative sequenceiVSP_022836451 – 558Missing in isoform 3. 1 PublicationAdd BLAST108
Alternative sequenceiVSP_022837562 – 570Missing in isoform 3. 1 Publication9

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
BC030580 mRNA Translation: AAH30580.1
BC049375 mRNA Translation: AAH49375.1
BC050723 mRNA Translation: AAH50723.1
BC071729 mRNA Translation: AAH71729.1

The Consensus CDS (CCDS) project

More...CCDSi		CCDS44776.1 [Q8NCP5-3]
CCDS73414.1 [Q8NCP5-1]
CCDS73415.1 [Q8NCP5-2]

NCBI Reference Sequences

More...RefSeqi		NP_001288027.1, NM_001301098.1
NP_001288028.1, NM_001301099.1 [Q8NCP5-2]
NP_054874.3, NM_014155.4 [Q8NCP5-3]
XP_016873112.1, XM_017017623.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000445008; ENSP00000408079; ENSG00000196323 [Q8NCP5-4]
ENST00000525842; ENSP00000433457; ENSG00000196323 [Q8NCP5-3]
ENST00000530205; ENSP00000434177; ENSG00000196323 [Q8NCP5-2]

Database of genes from NCBI RefSeq genomes

More...GeneIDi		29068

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hsa:29068

UCSC genome browser

More...UCSCi		uc001qfz.4 human [Q8NCP5-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC030580 mRNA Translation: AAH30580.1
BC049375 mRNA Translation: AAH49375.1
BC050723 mRNA Translation: AAH50723.1
BC071729 mRNA Translation: AAH71729.1
CCDSiCCDS44776.1 [Q8NCP5-3]
CCDS73414.1 [Q8NCP5-1]
CCDS73415.1 [Q8NCP5-2]
RefSeqiNP_001288027.1, NM_001301098.1
NP_001288028.1, NM_001301099.1 [Q8NCP5-2]
NP_054874.3, NM_014155.4 [Q8NCP5-3]
XP_016873112.1, XM_017017623.1

3D structure databases

SMRiQ8NCP5
ModBaseiSearch...

Protein-protein interaction databases

BioGridi118842, 28 interactors
IntActiQ8NCP5, 23 interactors
STRINGi9606.ENSP00000380861

PTM databases

iPTMnetiQ8NCP5
PhosphoSitePlusiQ8NCP5

Polymorphism and mutation databases

BioMutaiZBTB44
DMDMi74760158

Proteomic databases

jPOSTiQ8NCP5
MassIVEiQ8NCP5
MaxQBiQ8NCP5
PaxDbiQ8NCP5
PeptideAtlasiQ8NCP5
PRIDEiQ8NCP5
ProteomicsDBi72915 [Q8NCP5-1]
72916 [Q8NCP5-2]
72917 [Q8NCP5-3]
72918 [Q8NCP5-4]

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...Antibodypediai		33097 155 antibodies

The DNASU plasmid repository

More...DNASUi		29068

Genome annotation databases

EnsembliENST00000445008; ENSP00000408079; ENSG00000196323 [Q8NCP5-4]
ENST00000525842; ENSP00000433457; ENSG00000196323 [Q8NCP5-3]
ENST00000530205; ENSP00000434177; ENSG00000196323 [Q8NCP5-2]
GeneIDi29068
KEGGihsa:29068
UCSCiuc001qfz.4 human [Q8NCP5-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		29068

GeneCards: human genes, protein and diseases

More...GeneCardsi		ZBTB44
HGNCiHGNC:25001 ZBTB44
HPAiENSG00000196323 Low tissue specificity
neXtProtiNX_Q8NCP5
OpenTargetsiENSG00000196323
PharmGKBiPA162409447

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

eggNOGiKOG1721 Eukaryota
COG5048 LUCA
GeneTreeiENSGT00940000153306
HOGENOMiCLU_034849_1_0_1
InParanoidiQ8NCP5
KOiK10515
PhylomeDBiQ8NCP5
TreeFamiTF332673

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		ZBTB44 human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		29068
PharosiQ8NCP5 Tdark

Protein Ontology

More...PROi		PR:Q8NCP5
RNActiQ8NCP5 protein

Gene expression databases

BgeeiENSG00000196323 Expressed in quadriceps femoris and 216 other tissues
ExpressionAtlasiQ8NCP5 baseline and differential
GenevisibleiQ8NCP5 HS

Family and domain databases

InterProiView protein in InterPro
IPR000210 BTB/POZ_dom
IPR011333 SKP1/BTB/POZ_sf
IPR036236 Znf_C2H2_sf
IPR013087 Znf_C2H2_type
PfamiView protein in Pfam
PF00651 BTB, 1 hit
PF00096 zf-C2H2, 3 hits
SMARTiView protein in SMART
SM00225 BTB, 1 hit
SM00355 ZnF_C2H2, 4 hits
SUPFAMiSSF54695 SSF54695, 1 hit
SSF57667 SSF57667, 2 hits
PROSITEiView protein in PROSITE
PS50097 BTB, 1 hit
PS00028 ZINC_FINGER_C2H2_1, 4 hits
PS50157 ZINC_FINGER_C2H2_2, 4 hits

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiZBT44_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q8NCP5
Secondary accession number(s): Q6IPT8, Q86VJ7, Q86XX5
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 6, 2007
Last sequence update: October 1, 2002
Last modified: April 22, 2020
This is version 153 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human chromosome 11
    Human chromosome 11: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
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