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UniProtKB - Q8NBP0 (TTC13_HUMAN)

Entry version 152 (23 Feb 2022)
Sequence version 3 (04 Nov 2008)
Previous versions | rss
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Protein

Tetratricopeptide repeat protein 13

Gene

TTC13

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...PathwayCommonsi		Q8NBP0

SignaLink: a signaling pathway resource with multi-layered regulatory networks

More...SignaLinki		Q8NBP0

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Tetratricopeptide repeat protein 13
Short name:
TPR repeat protein 13
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:TTC13
ORF Names:PSEC0076
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 1

Organism-specific databases

Human Gene Nomenclature Database

More...HGNCi		HGNC:26204, TTC13

neXtProt; the human protein knowledge platform

More...neXtProti		NX_Q8NBP0

Eukaryotic Pathogen, Vector and Host Database Resources

More...VEuPathDBi		HostDB:ENSG00000143643

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...DisGeNETi		79573

Open Targets

More...OpenTargetsi		ENSG00000143643

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...PharmGKBi		PA134931681

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...Pharosi		Q8NBP0, Tdark

Genetic variation databases

BioMuta curated single-nucleotide variation and disease association database

More...BioMutai		TTC13

Domain mapping of disease mutations (DMDM)

More...DMDMi		212276494

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001063981 – 860Tetratricopeptide repeat protein 13Add BLAST860

Proteomic databases

Encyclopedia of Proteome Dynamics

More...EPDi		Q8NBP0

jPOST - Japan Proteome Standard Repository/Database

More...jPOSTi		Q8NBP0

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...MassIVEi		Q8NBP0

MaxQB - The MaxQuant DataBase

More...MaxQBi		Q8NBP0

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		Q8NBP0

PeptideAtlas

More...PeptideAtlasi		Q8NBP0

PRoteomics IDEntifications database

More...PRIDEi		Q8NBP0

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		72804 [Q8NBP0-1]
72805 [Q8NBP0-2]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		Q8NBP0

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		Q8NBP0

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSG00000143643, Expressed in granulocyte and 213 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		Q8NBP0, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		Q8NBP0, HS

Organism-specific databases

Human Protein Atlas

More...HPAi		ENSG00000143643, Low tissue specificity

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		122720, 67 interactors

Protein interaction database and analysis system

More...IntActi		Q8NBP0, 7 interactors

Molecular INTeraction database

More...MINTi		Q8NBP0

STRING: functional protein association networks

More...STRINGi		9606.ENSP00000355621

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		Q8NBP0, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		Q8NBP0

Database of comparative protein structure models

More...ModBasei		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati143 – 176TPR 1Add BLAST34
Repeati216 – 248TPR 2Add BLAST33
Repeati249 – 282TPR 3Add BLAST34
Repeati284 – 316TPR 4Add BLAST33
Repeati317 – 350TPR 5Add BLAST34
Repeati352 – 384TPR 6Add BLAST33
Repeati386 – 418TPR 7Add BLAST33

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

Repeat, TPR repeat

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG4626, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00940000158461

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_014101_1_0_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q8NBP0

Identification of Orthologs from Complete Genome Data

More...OMAi		SWHDVYS

Database of Orthologous Groups

More...OrthoDBi		118570at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		Q8NBP0

TreeFam database of animal gene trees

More...TreeFami		TF332283

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		1.25.40.10, 2 hits

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR011990, TPR-like_helical_dom_sf
IPR001440, TPR_1
IPR019734, TPR_repeat

Pfam protein domain database

More...Pfami		View protein in Pfam
PF00515, TPR_1, 1 hit
PF13181, TPR_8, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00028, TPR, 6 hits

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF48452, SSF48452, 2 hits

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS50005, TPR, 6 hits
PS50293, TPR_REGION, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 5 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q8NBP0-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <p><strong>What is the canonical sequence?</strong><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MAPAGCCCCC CFWGGAVAAA GAARRVLLLL LLGVLSAGLR PGALATEHYS 
        60         70         80         90        100
PLSLLKQELQ HRQQQEAPAG GGGCSPQSGD WGDQYSAECG ESSFLNFHDS 
       110        120        130        140        150
DCEPKGSSPC DSLLSLNTEK ILSQAKSIAE QKRFPFATDN DSTNEELAIA 
       160        170        180        190        200
YVLIGSGLYD EAIRHFSTML QEEPDLVSAI YGRGIAYGKK GLHDIKNAEL 
       210        220        230        240        250
ALFELSRVIT LEPDRPEVFE QRAEILSPLG RINEAVNDLT KAIQLQPSAR 
       260        270        280        290        300
LYRHRGTLYF ISEDYATAHE DFQQSLELNK NQPIAMLYKG LTFFHRGLLK 
       310        320        330        340        350
EAIESFKEAL KQKVDFIDAY KSLGQAYREL GNFEAATESF QKALLLNQNH 
       360        370        380        390        400
VQTLQLRGMM LYHHGSLQEA LKNFKRCLQL EPYNEVCQYM KGLSHVAMGQ 
       410        420        430        440        450
FYEGIKAQTK VMLNDPLPGQ KASPEYLKVK YLREYSRYLH AHLDTPLTEY 
       460        470        480        490        500
NIDVDLPGSF KDHWAKNLPF LIEDYEEQPG LQPHIKDVLH QNFESYKPEV 
       510        520        530        540        550
QELICVADRL GSLMQYETPG FLPNKRIHRA MGLAALEVMQ AVQRTWTNSK 
       560        570        580        590        600
VRMNGKTRLM QWRDMFDIAV KWRRIADPDQ PVLWLDQMPA RSLSRGFNNH 
       610        620        630        640        650
INLIRGQVIN MRYLEYFEKI LHFIKDRILV YHGANNPKGL LEVREALEKV 
       660        670        680        690        700
HKVEDLLPIM KQFNTKTKDG FTVNTKVPSL KDQGKEYDGF TITITGDKVG 
       710        720        730        740        750
NILFSVETQT TEERTQLYHA EIDALYKDLT AKGKVLILSS EFGEADAVCN 
       760        770        780        790        800
LILSLVYYFY NLMPLSRGSS VIAYSVIVGA LMASGKEVAG KIPKGKLVDF 
       810        820        830        840        850
EAMTAPGSEA FSKVAKSWMN LKSISPSYKT LPSVSETFPT LRSMIEVLNT 
       860
DSSPRCLKKL
Length:860
Mass (Da):96,813
Last modified:November 4, 2008 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i75747278086D7160
GO
Isoform 2 (identifier: Q8NBP0-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     172-224: Missing.
     662-662: Missing.

Show »
Length:806
Mass (Da):90,718
Checksum:i158BE03F91CBB8B0
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 5 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
H0YBV3H0YBV3_HUMAN
Tetratricopeptide repeat protein 13
TTC13
186Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
E5RJP6E5RJP6_HUMAN
Tetratricopeptide repeat protein 13
TTC13
150Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
E5RHB3E5RHB3_HUMAN
Tetratricopeptide repeat protein 13
TTC13
166Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
E5RG15E5RG15_HUMAN
Tetratricopeptide repeat protein 13
TTC13
255Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H0YB10H0YB10_HUMAN
Tetratricopeptide repeat protein 13
TTC13
123Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti38G → R in BAC11700 (PubMed:16303743).Curated1
Sequence conflicti438Y → H in BAC11586 (PubMed:16303743).Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_011644172 – 224Missing in isoform 2. 3 PublicationsAdd BLAST53
Alternative sequenceiVSP_035660662Missing in isoform 2. 3 Publications1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AK075386 mRNA Translation: BAC11586.1
AK075561 mRNA Translation: BAC11700.1
AL834453 mRNA Translation: CAD39113.1
AL844165 Genomic DNA No translation available.
FO393421 Genomic DNA No translation available.
BC042683 mRNA Translation: AAH42683.1

The Consensus CDS (CCDS) project

More...CCDSi		CCDS1588.1 [Q8NBP0-1]
CCDS44332.2 [Q8NBP0-2]

NCBI Reference Sequences

More...RefSeqi		NP_001116307.2, NM_001122835.2 [Q8NBP0-2]
NP_078801.3, NM_024525.4 [Q8NBP0-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000366661; ENSP00000355621; ENSG00000143643
ENST00000366662; ENSP00000355622; ENSG00000143643 [Q8NBP0-2]

Database of genes from NCBI RefSeq genomes

More...GeneIDi		79573

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hsa:79573

Matched Annotation from NCBI and EMBL-EBI (MANE) - Phase one

More...MANE-Selecti		ENST00000366661.9; ENSP00000355621.4; NM_024525.5; NP_078801.3

UCSC genome browser

More...UCSCi		uc001huf.5, human [Q8NBP0-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK075386 mRNA Translation: BAC11586.1
AK075561 mRNA Translation: BAC11700.1
AL834453 mRNA Translation: CAD39113.1
AL844165 Genomic DNA No translation available.
FO393421 Genomic DNA No translation available.
BC042683 mRNA Translation: AAH42683.1
CCDSiCCDS1588.1 [Q8NBP0-1]
CCDS44332.2 [Q8NBP0-2]
RefSeqiNP_001116307.2, NM_001122835.2 [Q8NBP0-2]
NP_078801.3, NM_024525.4 [Q8NBP0-1]

3D structure databases

SMRiQ8NBP0
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi122720, 67 interactors
IntActiQ8NBP0, 7 interactors
MINTiQ8NBP0
STRINGi9606.ENSP00000355621

PTM databases

iPTMnetiQ8NBP0
PhosphoSitePlusiQ8NBP0

Genetic variation databases

BioMutaiTTC13
DMDMi212276494

Proteomic databases

EPDiQ8NBP0
jPOSTiQ8NBP0
MassIVEiQ8NBP0
MaxQBiQ8NBP0
PaxDbiQ8NBP0
PeptideAtlasiQ8NBP0
PRIDEiQ8NBP0
ProteomicsDBi72804 [Q8NBP0-1]
72805 [Q8NBP0-2]

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...Antibodypediai		2494, 62 antibodies from 13 providers

The DNASU plasmid repository

More...DNASUi		79573

Genome annotation databases

EnsembliENST00000366661; ENSP00000355621; ENSG00000143643
ENST00000366662; ENSP00000355622; ENSG00000143643 [Q8NBP0-2]
GeneIDi79573
KEGGihsa:79573
MANE-SelectiENST00000366661.9; ENSP00000355621.4; NM_024525.5; NP_078801.3
UCSCiuc001huf.5, human [Q8NBP0-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		79573
DisGeNETi79573

GeneCards: human genes, protein and diseases

More...GeneCardsi		TTC13
HGNCiHGNC:26204, TTC13
HPAiENSG00000143643, Low tissue specificity
neXtProtiNX_Q8NBP0
OpenTargetsiENSG00000143643
PharmGKBiPA134931681
VEuPathDBiHostDB:ENSG00000143643

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

eggNOGiKOG4626, Eukaryota
GeneTreeiENSGT00940000158461
HOGENOMiCLU_014101_1_0_1
InParanoidiQ8NBP0
OMAiSWHDVYS
OrthoDBi118570at2759
PhylomeDBiQ8NBP0
TreeFamiTF332283

Enzyme and pathway databases

PathwayCommonsiQ8NBP0
SignaLinkiQ8NBP0

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		79573, 6 hits in 1045 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		TTC13, human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		79573
PharosiQ8NBP0, Tdark

Protein Ontology

More...PROi		PR:Q8NBP0
RNActiQ8NBP0, protein

Gene expression databases

BgeeiENSG00000143643, Expressed in granulocyte and 213 other tissues
ExpressionAtlasiQ8NBP0, baseline and differential
GenevisibleiQ8NBP0, HS

Family and domain databases

Gene3Di1.25.40.10, 2 hits
InterProiView protein in InterPro
IPR011990, TPR-like_helical_dom_sf
IPR001440, TPR_1
IPR019734, TPR_repeat
PfamiView protein in Pfam
PF00515, TPR_1, 1 hit
PF13181, TPR_8, 1 hit
SMARTiView protein in SMART
SM00028, TPR, 6 hits
SUPFAMiSSF48452, SSF48452, 2 hits
PROSITEiView protein in PROSITE
PS50005, TPR, 6 hits
PS50293, TPR_REGION, 1 hit

MobiDB: a database of protein disorder and mobility annotations

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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiTTC13_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q8NBP0
Secondary accession number(s): B1AQI1
, B1AQI2, Q8IVP8, Q8NBI0, Q8ND20
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 27, 2004
Last sequence update: November 4, 2008
Last modified: February 23, 2022
This is version 152 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human chromosome 1
    Human chromosome 1: entries, gene names and cross-references to MIM
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